BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 14-25F
(769 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
368,476 sequences; 112,640,273 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|3941720 (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRNA li... 196 1e-49
gi|549037|sp|P36421|SYYC_YEAST TYROSYL-TRNA SYNTHETASE, CYTOPLAS... 196 2e-49
gi|1711657|sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL-... 195 3e-49
gi|2665519 (U89436) tyrosyl-tRNA synthetase [Homo sapiens] >gi|4... 195 3e-49
gi|1584013|prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii] 190 1e-47
gi|3183174|sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLA... 182 2e-45
gi|4128224 (AF096709) tyrosyl-tRNA synthetase [Drosophila virilis] 152 2e-36
gi|3122912|sp|O29482|SYY_ARCFU TYROSYL-TRNA SYNTHETASE (TYROSINE... 121 6e-27
gi|2501079|sp|Q29465|SYY_BOVIN TYROSYL-TRNA SYNTHETASE (TYROSYL-... 119 2e-26
gi|2501077|sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE... 119 2e-26
gi|3334364|sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE... 106 2e-22
gi|2501078|sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE... 85 7e-16
gi|1841468|emb|CAA71881| (Y10990) Tyrosyl-tRNA synthetase [Nicot... 83 3e-15
gi|1707012 (U78721) tyrosyl-tRNA synthetase isolog [Arabidopsis ... 76 2e-13
gi|3257425|dbj|BAA30108| (AP000004) 375aa long hypothetical tyro... 58 8e-08
gi|135188|sp|P21656|SYW_BACSU TRYPTOPHANYL-TRNA SYNTHETASE (TRYP... 51 8e-06
gi|1174554|sp|P43836|SYY_HAEIN TYROSYL-TRNA SYNTHETASE (TYROSINE... 43 0.002
gi|3024674|sp|P56396|SYW_HELPY TRYPTOPHANYL-TRNA SYNTHETASE (TRY... 42 0.004
gi|4155771 (AE001544) TRYPTOPHANYL-TRNA SYNTHETASE [Helicobacter... 41 0.007
gi|135193|sp|P25151|SYY2_BACSU TYROSYL-TRNA SYNTHETASE 2 (TYROSI... 41 0.012
gi|98500|pir||S16426 tyrosine--tRNA ligase (EC 6.1.1.1) TyrZ - B... 41 0.012
gi|730884|sp|P41256|SYY_THIFE TYROSYL-TRNA SYNTHETASE (TYROSINE-... 40 0.021
gi|4454542|gb|AAD20941| (AF055668) apoptosis-linked gene 4, delt... 39 0.027
gi|4454544|gb|AAD20942| (AF055669) apoptosis-linked gene 4, F fo... 39 0.027
gi|2982724|dbj|BAA25288| (AB012222) tryptophan-tRNA synthetase [... 39 0.036
gi|32709|emb|CAA44450| (X62570) IFP53 [Homo sapiens] 39 0.036
gi|837|emb|CAA36356| (X52113) tryptophan tRNA ligase (AA 1-459) ... 38 0.061
gi|88944|pir||JH0533 tryptophan--tRNA ligase (EC 6.1.1.2) - huma... 38 0.061
gi|135191|sp|P23381|SYW_HUMAN TRYPTOPHANYL-TRNA SYNTHETASE (TRYP... 38 0.061
gi|2984054 (AE000754) tyrosyl tRNA synthetase [Aquifex aeolicus] 38 0.061
gi|135189|sp|P17248|SYW_BOVIN TRYPTOPHANYL-TRNA SYNTHETASE (TRYP... 38 0.061
gi|165011 (M33460) eucaryotic release factor (eRF) [Oryctolagus ... 38 0.061
gi|68510|pir||YWRBPR translation releasing factor eRF - rabbit 38 0.061
gi|2851538|sp|P23612|SYW_RABIT TRYPTOPHANYL-TRNA SYNTHETASE (TRY... 38 0.061
gi|2501074|sp|Q12109|SYWC_YEAST TRYPTOPHANYL-TRNA SYNTHETASE, CY... 37 0.14
gi|3024675|sp|P56417|SYY_HELPY TYROSYL-TRNA SYNTHETASE (TYROSINE... 36 0.24
gi|417846|sp|P32921|SYW_MOUSE TRYPTOPHANYL-TRNA SYNTHETASE (TRYP... 36 0.24
gi|55436|emb|CAA49347| (X69656) tryptophan--tRNA ligase [Mus mus... 36 0.24
gi|462693|sp|P80303|NEFA_HUMAN DNA-BINDING PROTEIN NEFA PRECURSO... 36 0.31
gi|2501076|sp|P73141|SYY_SYNY3 TYROSYL-TRNA SYNTHETASE (TYROSINE... 35 0.53
gi|4155267 (AE001502) TYROSYL-TRNA SYNTHETASE [Helicobacter pylo... 34 1.2
gi|4557060|gb|AAD22500|AC007154_4 (AC007154) putative chromosome... 34 1.2
gi|2501072|sp|P73655|SYW_SYNY3 TRYPTOPHANYL-TRNA SYNTHETASE (TRY... 32 4.6
>gi|3941720 (AF087021) tyrosyl-tRNA synthetase; tyrosine--tRNA ligase [Bos
taurus]
Length = 528
Score = 196 bits (494), Expect = 1e-49
Identities = 98/210 (46%), Positives = 145/210 (68%), Gaps = 1/210 (0%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
++QLS +YT+D+Y+ ++ HDA++AG+ VVKQ E L S ++YP LQALDEEYL VD
Sbjct: 122 DYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDA 181
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHI 361
QFGGVDQRKIF +AEK LP +GY KRIHL+NPM+PGL KMS+S+E SKIDLLD + +
Sbjct: 182 QFGGVDQRKIFTFAEKYLPALGYSKRIHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDV 241
Query: 362 TKKMQKPFCEEG-IINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIE 538
KK++K FCE G + N G+ ++H+ P+ E I+ + T ++Y ++E
Sbjct: 242 KKKLKKAFCEPGNVENNGVLAFIRHVLFPLKS----EFVILRDEKWGGNKT-YTAYLDLE 296
Query: 539 EKYKNKNIHPGDFKMALAEIIKRIITPIREE 631
+ + ++ +HPGD K ++ + +++ PIRE+
Sbjct: 297 KDFADEVVHPGDLKNSVEVALNKLLDPIREK 327
>gi|549037|sp|P36421|SYYC_YEAST TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|539380|pir||A45999 tyrosine--tRNA ligase (EC
6.1.1.1) - yeast (Saccharomyces cerevisiae) >gi|173120
(L12221) tyrosyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1323328|emb|CAA97211| (Z72970) ORF
YGR185c [Saccharomyces cerevisiae]
>gi|1430951|emb|CAA67529| (X99074) G7522 [Saccharomyces
cerevisiae]
Length = 394
Score = 196 bits (492), Expect = 2e-49
Identities = 99/215 (46%), Positives = 147/215 (68%), Gaps = 8/215 (3%)
Query: 5 FQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQ 184
+QL+P YTMD+++ I +DA+RAG+ VVKQ + L S ++YPL+QALDE++LDVD Q
Sbjct: 127 YQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQ 186
Query: 185 FGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGL-NSDKMSASDEYSKIDLLDSDKHI 361
FGGVDQRKIF+ AE++LP +GY+KR HL+NPM+PGL KMSASD SKIDLL+ K +
Sbjct: 187 FGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQV 246
Query: 362 TKKMQKPFCEEGIINE-GLFMLLKHIXLPIVDIK------GWEIDIVTNLGSPLRVTGKS 520
KK+ FC G + E GL ++++ PI ++K + ID G P+
Sbjct: 247 KKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITY---K 303
Query: 521 SYDEIEEKYKNKNIHPGDFKMALAEIIKRIITPIREEMFXNQD 649
S++E++ +K + + P D K+ +A+ I ++ PIR+E N++
Sbjct: 304 SFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKE 346
>gi|1711657|sp|P54577|SYY_HUMAN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGASE) (TYRRS) >gi|1184699
(U40714) tyrosyl-tRNA synthetase [Homo sapiens]
Length = 388
Score = 195 bits (490), Expect = 3e-49
Identities = 96/210 (45%), Positives = 144/210 (67%), Gaps = 1/210 (0%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
++QLS +YT+D+Y+ ++ HD+++AG+ VVKQ E L S ++YP LQALDEEYL VD
Sbjct: 122 DYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDA 181
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHI 361
QFGG+DQRKIF +AEK LP +GY KR+HL+NPM+PGL KMS+S+E SKIDLLD + +
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDV 241
Query: 362 TKKMQKPFCEEG-IINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIE 538
KK++K FCE G + N G+ +KH+ P+ E I+ + T ++Y ++E
Sbjct: 242 KKKLKKAFCEPGNVENNGVLSFIKHVLFPLKS----EFVILRDEKWGGNKT-YTAYVDLE 296
Query: 539 EKYKNKNIHPGDFKMALAEIIKRIITPIREE 631
+ + + +HPGD K ++ + +++ PIRE+
Sbjct: 297 KDFAAEVVHPGDLKNSVEVALNKLLDPIREK 327
>gi|2665519 (U89436) tyrosyl-tRNA synthetase [Homo sapiens]
>gi|4507947|ref|NP_003671.1|pYARS| tyrosyl-tRNA
synthetase; tyrosyl tRNA ligase
Length = 528
Score = 195 bits (490), Expect = 3e-49
Identities = 96/210 (45%), Positives = 144/210 (67%), Gaps = 1/210 (0%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
++QLS +YT+D+Y+ ++ HD+++AG+ VVKQ E L S ++YP LQALDEEYL VD
Sbjct: 122 DYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDA 181
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHI 361
QFGG+DQRKIF +AEK LP +GY KR+HL+NPM+PGL KMS+S+E SKIDLLD + +
Sbjct: 182 QFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDV 241
Query: 362 TKKMQKPFCEEG-IINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIE 538
KK++K FCE G + N G+ +KH+ P+ E I+ + T ++Y ++E
Sbjct: 242 KKKLKKAFCEPGNVENNGVLSFIKHVLFPLKS----EFVILRDEKWGGNKT-YTAYVDLE 296
Query: 539 EKYKNKNIHPGDFKMALAEIIKRIITPIREE 631
+ + + +HPGD K ++ + +++ PIRE+
Sbjct: 297 KDFAAEVVHPGDLKNSVEVALNKLLDPIREK 327
>gi|1584013|prf||2122232A Tyr-tRNA synthetase [Pneumocystis carinii]
Length = 370
Score = 190 bits (477), Expect = 1e-47
Identities = 104/221 (47%), Positives = 148/221 (66%), Gaps = 8/221 (3%)
Query: 5 FQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQ 184
+QLS KY MD ++ TI HDA++AG+ VVKQ E+ L S ++YP +QALDEEYLD D Q
Sbjct: 124 YQLSSKYCMDNFRLCTIVTEHDAKKAGAEVVKQVENSLLSGLLYPGMQALDEEYLDSDAQ 183
Query: 185 FGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSAS-DEYSKIDLLDSDKHI 361
FGGVDQRKIF +AEK LP +G +KRIHL++PMIPGL KMSAS +E +KID+LD + +
Sbjct: 184 FGGVDQRKIFTFAEKYLPMLGLKKRIHLMSPMIPGLAGGKMSASGNENNKIDILDDAETV 243
Query: 362 TKKMQKPFCEEGII-NEGLFMLLKHIXLPIVDIKG---WEIDIVTNLGSPLRVTGKSSYD 529
KK+ K C E + N GL L KH+ P++ +KG I+ G P+ +SY+
Sbjct: 244 KKKINKALCVEAAVENNGLLELAKHVIFPVLALKGIPALTINREEKWGGPV---SYNSYE 300
Query: 530 EIEEKYKNKNIHPGDFKMALAEIIKRIITPIREEMFXN---QDLIDNAY 667
+E +Y N+ + P D K+ +++ + ++ IR E N Q+++ AY
Sbjct: 301 LLELEYVNRKLSPQDLKIGISDSLNFLLESIRLEFAENKEFQEILHLAY 349
>gi|3183174|sp|O14055|SYYC_SCHPO TYROSYL-TRNA SYNTHETASE, CYTOPLASMIC (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|3451306|emb|CAA20443| (AL031324) tyrosyl-trna
synthetase cytoplasmic EC 6.1.1.1 [Schizosaccharomyces
pombe]
Length = 401
Score = 182 bits (458), Expect = 2e-45
Identities = 95/216 (43%), Positives = 143/216 (65%), Gaps = 5/216 (2%)
Query: 5 FQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQ 184
+QL YT+D ++ T H A+RAG+ VVKQ S L SS++YP +QALDE+YL VDVQ
Sbjct: 121 YQLKEDYTLDNFRLAASTTEHTARRAGAEVVKQVASPLLSSLIYPGMQALDEQYLGVDVQ 180
Query: 185 FGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSAS-DEYSKIDLLDSDKHI 361
FGGVDQRKIF+ AE+ LP +GY+KR HL+NPM+P L KMS+S +KID+LD K +
Sbjct: 181 FGGVDQRKIFVMAEEVLPVLGYKKRGHLMNPMVPSLAGGKMSSSAAANAKIDILDDPKTV 240
Query: 362 TKKMQKPFCEEGIINE-GLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGK---SSYD 529
KK++ FCE G++ E G LK++ P ++++G E + V + P + G+ +Y+
Sbjct: 241 NKKIRSAFCEPGVVEENGCLAFLKYVSFPAMELRG-ETEFV--IDRPEQFGGRMVFKTYE 297
Query: 530 EIEEKYKNKNIHPGDFKMALAEIIKRIITPIREEMFXNQDL 652
E+E+ YK+ + P D K+ L + ++ ++E++ DL
Sbjct: 298 EVEKAYKDLTLSPQDLKLGLESSVNTLLAGVQEQLKQYPDL 338
>gi|4128224 (AF096709) tyrosyl-tRNA synthetase [Drosophila virilis]
Length = 237
Score = 152 bits (381), Expect = 2e-36
Identities = 72/115 (62%), Positives = 92/115 (79%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
++QLS +YT+D+YK ++ HDA++AG+ VVKQ E L S ++YP LQ LDEEYL VD
Sbjct: 123 DYQLSREYTLDVYKLSSLVTIHDAKKAGAEVVKQVEHPLLSCLLYPGLQGLDEEYLKVDA 182
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLD 346
QFGGVDQRKIF ++EK LP++GYEKRIH +NPM+PGL KMS+S+E SKIDLLD
Sbjct: 183 QFGGVDQRKIFTFSEKYLPQLGYEKRIHFMNPMVPGLAGGKMSSSEEDSKIDLLD 237
>gi|3122912|sp|O29482|SYY_ARCFU TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS) >gi|2649832
(AE001051) tyrosyl-tRNA synthetase (tyrS) [Archaeoglobus
fulgidus]
Length = 323
Score = 121 bits (300), Expect = 6e-27
Identities = 69/211 (32%), Positives = 124/211 (58%), Gaps = 6/211 (2%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
E+QLS Y +D+ K IT + A+R+ V ++ E + S ++YPL+QALD +L VD+
Sbjct: 114 EYQLSRDYVLDVLKMARITTLNRARRSMDEVSRRKEDPMVSQMIYPLMQALDIAHLGVDL 173
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHI 361
GG+DQRKI + A ++LP++GY + L P++ GL+ KMS+S + + I + D + +
Sbjct: 174 AVGGIDQRKIHMLARENLPRLGYSSPVCLHTPILVGLDGQKMSSS-KGNYISVRDPPEEV 232
Query: 362 TKKMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEI-----DIVTNLGSPLRVTGK-SS 523
+K++K +C G++ E PI+DI + I IV + + +S
Sbjct: 233 ERKIRKAYCPAGVVEEN----------PILDIAKYHILPRFGKIVVERDAKFGGDVEYAS 282
Query: 524 YDEIEEKYKNKNIHPGDFKMALAEIIKRIITPIREEM 634
++E+ E +K+ +HP D K+A+A+ + ++ R+ +
Sbjct: 283 FEELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARKRL 319
>gi|2501079|sp|Q29465|SYY_BOVIN TYROSYL-TRNA SYNTHETASE (TYROSYL--TRNA LIGASE) (TYRRS)
>gi|1212808|emb|CAA65245| (X96373) tyrosyl-tRNA
synthetase [Bos taurus]
Length = 196
Score = 119 bits (295), Expect = 2e-26
Identities = 56/91 (61%), Positives = 71/91 (77%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
++QLS +YT+D+Y+ ++ HDA++AG+ VVKQ E L S ++YP LQALDEEYL VD
Sbjct: 106 DYQLSKEYTLDVYRLSSVVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDA 165
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLIN 274
QFGGVDQRKIF +AEK LP GY KRIHL+N
Sbjct: 166 QFGGVDQRKIFTFAEKYLPAPGYSKRIHLMN 196
>gi|2501077|sp|Q57834|SYY_METJA TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|2129341|pir||E64348 tyrosine--tRNA ligase (EC
6.1.1.1) - Methanococcus jannaschii >gi|1591094 (U67491)
tyrosyl-tRNA synthetase (trS) [Methanococcus jannaschii]
Length = 306
Score = 119 bits (295), Expect = 2e-26
Identities = 67/211 (31%), Positives = 120/211 (56%), Gaps = 3/211 (1%)
Query: 2 EFQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDV 181
EFQL YT+++Y+ T A+R+ + ++ E+ + ++YP++Q D YL VDV
Sbjct: 107 EFQLDKDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNDIHYLGVDV 166
Query: 182 QFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHI 361
GG++QRKI + A + LPK K + + NP++ GL+ + +S + + I + DS + I
Sbjct: 167 AVGGMEQRKIHMLARELLPK----KVVCIHNPVLTGLDGEGKMSSSKGNFIAVDDSPEEI 222
Query: 362 TKKMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGK---SSYDE 532
K++K +C G++ PI++I + ++ + P + G +SY+E
Sbjct: 223 RAKIKKAYCPAGVVEGN----------PIMEIAKYFLEYPLTIKRPEKFGGDLTVNSYEE 272
Query: 533 IEEKYKNKNIHPGDFKMALAEIIKRIITPIREEM 634
+E +KNK +HP D K A+AE + +I+ PIR+ +
Sbjct: 273 LESLFKNKELHPMDLKNAVAEELIKILEPIRKRL 306
>gi|3334364|sp|O27795|SYY_METTH TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS) >gi|2622897
(AE000932) tyrosyl-tRNA synthetase [Methanobacterium
thermoautotrophicum]
Length = 319
Score = 106 bits (262), Expect = 2e-22
Identities = 62/210 (29%), Positives = 120/210 (56%), Gaps = 4/210 (1%)
Query: 5 FQLSPKYTMDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQ 184
FQ P+YT +Y+ IT A+R+ + + +++ + ++YPL+Q +D YL VDV
Sbjct: 112 FQTEPEYTDLVYRLALITTLLRAKRSMAQITRESRDHKVAEVIYPLMQVIDMVYLGVDVA 171
Query: 185 FGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHIT 364
GG++QRKI + A ++LP++G++ + + P++ G + + +S + + I + DS I
Sbjct: 172 LGGMEQRKIHMLARENLPRLGFDAPVCIHTPLLHGTDGSEKMSSSKGNFIAVDDSPDEIR 231
Query: 365 KKMQKPFCEEGIINEG--LFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTG--KSSYDE 532
+K++K +C G EG + ++K+ +P E ++T + P + G + DE
Sbjct: 232 EKVKKSYCPMG-ETEGNPIIEIVKYFIMP-------EYGMMT-IRRPEKFGGDLELELDE 282
Query: 533 IEEKYKNKNIHPGDFKMALAEIIKRIITPIREEM 634
+ E Y + +HP D K A+++ + ++ P+RE M
Sbjct: 283 LLEMYSSSELHPLDLKNAVSDYLVDMLEPVREYM 316
>gi|2501078|sp|P95982|SYY_SULSO TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|1707816|emb|CAA69524| (Y08257) tyrosyl tRNA
synthetase [Sulfolobus solfataricus]
Length = 366
Score = 84.7 bits (206), Expect = 7e-16
Identities = 56/171 (32%), Positives = 87/171 (50%), Gaps = 19/171 (11%)
Query: 122 SSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSD 301
S ++YP +Q D YLD+D+ GG DQRK + A K+G +K + + P++ GL
Sbjct: 163 SKLIYPAMQVSDIFYLDLDIALGGTDQRKAHMLARDVAEKMGKKKIVSIHTPLLVGLQGG 222
Query: 302 ------------------KMSASDEYSKIDLLDSDKHITKKMQKPFCEEGII-NEGLFML 424
KMS S S I + DS + + +K+ +C +G+ N + +
Sbjct: 223 QRMNITEGMEEDDIQAEIKMSKSKPESAIFVNDSREDVERKIMGAYCPKGVAENNPILQI 282
Query: 425 LKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDFKMALAEIIK 604
LK+I P + E DI G + Y+E+E Y IHP D K A +
Sbjct: 283 LKYIIFPRYNFVKIERDI--KYGGDVEF---KDYEELERTYIEGKIHPMDLKKTTARKLN 337
Query: 605 RIITPIREEM 634
I+ PIR+ +
Sbjct: 338 EILEPIRKSL 347
>gi|1841468|emb|CAA71881| (Y10990) Tyrosyl-tRNA synthetase [Nicotiana tabacum]
Length = 408
Score = 82.7 bits (201), Expect = 3e-15
Identities = 57/186 (30%), Positives = 99/186 (52%), Gaps = 4/186 (2%)
Query: 101 QTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYE-KRIHLINP 277
+ + L + I YP +Q D +L D+ G+DQRK+ + A + I + K I L +
Sbjct: 212 EQDELTAAQIFYPCMQCADIFFLKADICQLGMDQRKVNVLAREYCDDIRRKNKPIILSHH 271
Query: 278 MIPGLNS--DKMSASDEYSKIDLLDSDKHITKKMQKPFCEEGIINEGLFM-LLKHIXLPI 448
M+PGL +KMS SD S I + D + + K++K FC ++ + + +K+I LP
Sbjct: 272 MLPGLQEGQEKMSKSDPSSSIYMEDEEADVNLKIKKAFCPPKVVEKNPCLEYIKYIVLPW 331
Query: 449 VDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDFKMALAEIIKRIITPIRE 628
+ E I + + T K+ ++E+ Y++ N+HP D K AL++ I +I+ P+R+
Sbjct: 332 FN----EFKIERSAENGADKTYKN-FEELAADYESGNLHPADLKPALSKAINKILQPVRD 386
Query: 629 EMFXNQDLID 658
+Q D
Sbjct: 387 HFKNDQKAKD 396
>gi|1707012 (U78721) tyrosyl-tRNA synthetase isolog [Arabidopsis thaliana]
Length = 460
Score = 76.5 bits (185), Expect = 2e-13
Identities = 54/174 (31%), Positives = 90/174 (51%), Gaps = 4/174 (2%)
Query: 101 QTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYE-KRIHLINP 277
+T+ L + I+YP +Q D +L+ D+ G+DQRK+ + A + I + K I L +
Sbjct: 155 ETDELSAAQILYPCMQCADIFFLEADICQLGMDQRKVNVLAREYCDDIKRKNKPIILSHH 214
Query: 278 MIPGL--NSDKMSASDEYSKIDLLDSDKHITKKMQKPFCEEGII-NEGLFMLLKHIXLPI 448
M+PGL +KMS SD S I + D + + K++K +C ++ +K+I LP
Sbjct: 215 MLPGLQQGQEKMSKSDPLSAIFMEDEEAEVNVKIKKAYCPPKVVKGNPCLEYIKYIILPW 274
Query: 449 VDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDFKMALAEIIKRIITPI 622
D E + N T K S+++I Y++ +HPGD K L + +I+ I
Sbjct: 275 FD----EFTVERNEEYGGNKTYK-SFEDIAADYESGELHPGDLKKGLMNALNKILQVI 327
>gi|3257425|dbj|BAA30108| (AP000004) 375aa long hypothetical tyrosyl-tRNA synthetase
[Pyrococcus horikoshii]
Length = 375
Score = 57.8 bits (137), Expect = 8e-08
Identities = 50/199 (25%), Positives = 98/199 (49%), Gaps = 28/199 (14%)
Query: 29 MDMYKXLTITKAHDAQRAGSAVVKQT-ESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQR 205
+D+ K +T+++ R+ + + +Q E++ + ++YP++Q D Y V + G+DQR
Sbjct: 135 IDISKNVTLSRV---MRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQGVTIAHAGMDQR 191
Query: 206 KIFIYAEKSLPKIGYEKRIHLINPMIP---------GLNSD------------------K 304
K + A + K+ Y +H + P GL K
Sbjct: 192 KAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESEEEFKEIKAQMK 251
Query: 305 MSASDEYSKIDLLDSDKHITKKMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDIVT 484
MS S YS + + DS + I +K++K FC + + + + + +
Sbjct: 252 MSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYIIFREEPTEFTVHRPA 311
Query: 485 NLGSPLRVTGKSSYDEIEEKYKNKNIHPGDFKMALAEIIKRIITPIR 625
G + T +++E++ + +HP D K A+AE + ++ PIR
Sbjct: 312 KFGGDVTYT---TFEELKRDFAEGKLHPLDLKNAVAEYLINLLEPIR 355
>gi|135188|sp|P21656|SYW_BACSU TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
>gi|68508|pir||YWBS tryptophan--tRNA ligase (EC 6.1.1.2)
- Bacillus subtilis >gi|143786 (M24068)
tryptophanyl-tRNA synthetase (EC 6.1.1.2) [Bacillus
subtilis] >gi|2633496|emb|CAB12999| (Z99110)
tryptophanyl-tRNA synthetase [Bacillus subtilis]
Length = 330
Score = 51.2 bits (120), Expect = 8e-06
Identities = 53/180 (29%), Positives = 85/180 (46%), Gaps = 20/180 (11%)
Query: 98 KQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRK------------------IFIYA 223
K E+++ + YP L A D D+ G DQ++ IF
Sbjct: 114 KGNEAVVSGLLTYPPLMAADILLYGTDLVPVGEDQKQHLELTRNLAERFNKKYNDIFTIP 173
Query: 224 EKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSK--IDLLDSDKHITKKMQKPFCEEG 397
E +PK+G RI +N + KMS SD K I LLD K + KK++ +
Sbjct: 174 EVKIPKVG--ARIMSLNDPLK-----KMSKSDPNQKAYITLLDEPKQLEKKIKSAVTD-- 224
Query: 398 IINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDF 577
+EG+ K V+NL + + G ++ +E+E KY+ K G+F
Sbjct: 225 --SEGIVKFDKE-----------NKPGVSNLLTIYSILGNTTIEELEAKYEGKGY--GEF 269
Query: 578 KMALAEIIKRIITPIREEMF 637
K LAE++ + PI++ +
Sbjct: 270 KGDLAEVVVNALKPIQDRYY 289
>gi|1174554|sp|P43836|SYY_HAEIN TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|1075409|pir||D64132 tyrosine--tRNA ligase (EC
6.1.1.1) - Haemophilus influenzae (strain Rd KW20)
>gi|1574452 (U32834) tyrosyl tRNA synthetase (tyrS)
[Haemophilus influenzae Rd]
Length = 401
Score = 43.0 bits (99), Expect = 0.002
Identities = 19/58 (32%), Positives = 32/58 (54%)
Query: 131 VYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDK 304
+YPLLQ D LD DV+ GG DQ+ + + G + ++ + P++ GL+ +K
Sbjct: 168 IYPLLQGYDSVALDADVELGGTDQKFNLLVGRELQKSAGKKPQVAITLPLLVGLDGEK 225
>gi|3024674|sp|P56396|SYW_HELPY TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
>gi|2314417|gb|AAD08297.1| (AE000630) tryptophanyl-tRNA
synthetase (trpS) [Helicobacter pylori 26695]
Length = 339
Score = 42.2 bits (97), Expect = 0.004
Identities = 51/178 (28%), Positives = 76/178 (42%), Gaps = 19/178 (10%)
Query: 95 VKQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGY-------- 250
+K +S+ YP+L A D D+ G DQ++ K
Sbjct: 128 LKNPKSVNVGLFNYPILMASDILLYQSDLVPVGEDQKQHLELTRNIAEKFNRDFGNCFKV 187
Query: 251 -EKRIHLINPMIPGLNSDKMSASDEYS----KIDLLDSDKHITKKMQKPFCEE-GII--- 403
E I + + GL+ K+ S + I LLD I KK++K + G+I
Sbjct: 188 PEPLIAKVGARVMGLDDPKVKMSKSHQGANHAIFLLDEPDIIVKKIKKAATDSMGVIAFD 247
Query: 404 --NEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDF 577
EG+F LL L S + IEE++KNK GDF
Sbjct: 248 EKREGIFNLLNIYML----------------------LSNESPENIEERFKNKGY--GDF 283
Query: 578 KMALAEIIKRIITPIRE 628
K LAE++ + + PI+E
Sbjct: 284 KKELAEVMIQALKPIQE 300
>gi|4155771 (AE001544) TRYPTOPHANYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 326
Score = 41.4 bits (95), Expect = 0.007
Identities = 51/178 (28%), Positives = 81/178 (44%), Gaps = 19/178 (10%)
Query: 95 VKQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGY-------- 250
+K +S+ YP+L A D D+ G DQ++ K
Sbjct: 115 LKNPKSVNVGLFNYPILMASDILLYQSDLVPVGEDQKQHLELTRNVAEKFNRDFGNCFKV 174
Query: 251 -EKRIHLINPMIPGLNSDKMSASDEYS----KIDLLDSDKHITKKMQKPFCEE-GII--- 403
E I + + GL+ K+ S + I LLD I KK++K + G+I
Sbjct: 175 PEPLIAKVGARVMGLDDPKVKMSKSHKGANHAIFLLDEPDVIVKKIKKAATDSMGVIAFD 234
Query: 404 --NEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKYKNKNIHPGDF 577
EG+F LL +I + + D S ++IEE+++NK GDF
Sbjct: 235 ETREGVFNLL-NIYMLLSD---------------------ESPEKIEERFRNKGY--GDF 270
Query: 578 KMALAEIIKRIITPIRE 628
K LAE++ + + PI+E
Sbjct: 271 KKELAEVVIQSLKPIQE 287
>gi|135193|sp|P25151|SYY2_BACSU TYROSYL-TRNA SYNTHETASE 2 (TYROSINE--TRNA LIGASE) (TYRRS 2)
>gi|40242|emb|CAA36724| (X52480) tyrosine tRNA
synthetase [Bacillus subtilis]
Length = 412
Score = 40.6 bits (93), Expect = 0.012
Identities = 20/61 (32%), Positives = 34/61 (54%), Gaps = 1/61 (1%)
Query: 134 YPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS-DKMS 310
YPL+Q D L+ D++ GG DQ + + EK++ ++ P++ GL+ +KMS
Sbjct: 184 YPLMQGYDSVVLESDIELGGTDQHFNVLMGRHFQERYNKEKQVVILMPLLEGLDGVEKMS 243
Query: 311 AS 316
S
Sbjct: 244 KS 245
>gi|98500|pir||S16426 tyrosine--tRNA ligase (EC 6.1.1.1) TyrZ - Bacillus subtilis
>gi|413933|emb|CAA51565| (X73124) ipa-9r [Bacillus
subtilis] >gi|2636381|emb|CAB15872| (Z99123)
tyrosyl-tRNA synthetase [Bacillus subtilis]
Length = 413
Score = 40.6 bits (93), Expect = 0.012
Identities = 20/61 (32%), Positives = 34/61 (54%), Gaps = 1/61 (1%)
Query: 134 YPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS-DKMS 310
YPL+Q D L+ D++ GG DQ + + EK++ ++ P++ GL+ +KMS
Sbjct: 185 YPLMQGYDSVVLESDIELGGTDQHFNVLMGRHFQERYNKEKQVVILMPLLEGLDGVEKMS 244
Query: 311 AS 316
S
Sbjct: 245 KS 246
>gi|730884|sp|P41256|SYY_THIFE TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|1075524|pir||A55515 tyrosine--tRNA ligase (EC
6.1.1.1) - Thiobacillus ferrooxidans
>gi|505366|emb|CAA55643| (X79010) tyrosine--tRNA ligase
[Thiobacillus ferrooxidans]
Length = 407
Score = 39.9 bits (91), Expect = 0.021
Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 131 VYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS-DKM 307
+YPLLQ D + DV+ GG DQR + + + G + ++ L P++ GL+ KM
Sbjct: 173 LYPLLQGYDSVAIKADVELGGTDQRFNLLVGRELQREYGQKPQLVLTMPILEGLDGVQKM 232
Query: 308 SAS 316
S S
Sbjct: 233 SKS 235
>gi|4454542|gb|AAD20941| (AF055668) apoptosis-linked gene 4, deltaC form [Mus musculus]
Length = 768
Score = 39.5 bits (90), Expect = 0.027
Identities = 24/43 (55%), Positives = 32/43 (73%), Gaps = 13/43 (30%)
Query: 387 QKGFCIFLVICLSESNRSILLYSSDALI-----------LSELRPG--IIGFIKCI 259
Q G + V+CLS+S R ILL AL+ LSE++PG +IGF+KCI
Sbjct: 291 QTGDTLHRVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCI 346
>gi|4454544|gb|AAD20942| (AF055669) apoptosis-linked gene 4, F form [Mus musculus]
Length = 225
Score = 39.5 bits (90), Expect = 0.027
Identities = 24/43 (55%), Positives = 32/43 (73%), Gaps = 13/43 (30%)
Query: 387 QKGFCIFLVICLSESNRSILLYSSDALI-----------LSELRPG--IIGFIKCI 259
Q G + V+CLS+S R ILL AL+ LSE++PG +IGF+KCI
Sbjct: 16 QTGDTLHRVLCLSQSERHILLCRKPALVSTVEGGQDPKSLSEIQPGMLLIGFVKCI 71
>gi|2982724|dbj|BAA25288| (AB012222) tryptophan-tRNA synthetase [Cavia porcellus]
Length = 305
Score = 39.1 bits (89), Expect = 0.036
Identities = 26/62 (41%), Positives = 30/62 (47%), Gaps = 2/62 (3%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IGY K L + P L KMSASD S I L DS K I
Sbjct: 145 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDSAKQIKT 204
Query: 368 KMQK 379
K+ K
Sbjct: 205 KVNK 208
>gi|32709|emb|CAA44450| (X62570) IFP53 [Homo sapiens]
Length = 471
Score = 39.1 bits (89), Expect = 0.036
Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 3/140 (2%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IGY K L + P L KMSASD S I L D+ K I
Sbjct: 311 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370
Query: 368 KMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDI-VTNLGSPLRVTGKSSYDEIEEK 544
K+ K + G + +H G D+ V+ + + ++I +
Sbjct: 371 KVNK-----HAFSGGRDTIEEHRQF------GGNCDVDVSFMYLTFFLEDDDKLEQIRKD 419
Query: 545 YKNKNIHPGDFKMALAEIIKRII 613
Y + + G+ K AL E+++ +I
Sbjct: 420 YTSGRMLTGELKKALIEVLQPLI 442
>gi|837|emb|CAA36356| (X52113) tryptophan tRNA ligase (AA 1-459) [Bos taurus]
Length = 459
Score = 38.3 bits (87), Expect = 0.061
Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 13/114 (11%)
Query: 38 YKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQA-------LDEEYLD-VDVQF-- 187
YK + + H + T+S I +P +QA + + D DVQ
Sbjct: 236 YKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDVQCLI 295
Query: 188 -GGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKH 358
+DQ F P+IGY K L + P L KMSASD S I L D+ K
Sbjct: 296 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQ 355
Query: 359 ITKKMQK 379
I K+ K
Sbjct: 356 IKTKVNK 362
>gi|88944|pir||JH0533 tryptophan--tRNA ligase (EC 6.1.1.2) - human >gi|340368 (M61715)
transfer RNA-Trp synthetase [Homo sapiens]
Length = 471
Score = 38.3 bits (87), Expect = 0.061
Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 3/140 (2%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IGY K L + P L KMSASD S I L D+ K I
Sbjct: 311 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370
Query: 368 KMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDI-VTNLGSPLRVTGKSSYDEIEEK 544
K+ K + G + +H G D+ V+ + + ++I +
Sbjct: 371 KVNK-----HAFSGGRDTIEEHRQF------GGNCDVDVSFMYLTFFLEDDDKLEQIRKD 419
Query: 545 YKNKNIHPGDFKMALAEIIKRII 613
Y + + G+ K AL E+++ +I
Sbjct: 420 YTSGAMLTGELKKALIEVLQPLI 442
>gi|135191|sp|P23381|SYW_HUMAN TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
(IFP53) >gi|107990|pir||A41706 tryptophan--tRNA ligase
homolog - human >gi|30821|emb|CAA42545| (X59892) 471 aa
polypeptide (gamma2) [Homo sapiens] >gi|184657 (M77804)
transfer RNA-Trp synthetase [Homo sapiens]
Length = 471
Score = 38.3 bits (87), Expect = 0.061
Identities = 38/140 (27%), Positives = 60/140 (42%), Gaps = 3/140 (2%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IGY K L + P L KMSASD S I L D+ K I
Sbjct: 311 IDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKT 370
Query: 368 KMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDI-VTNLGSPLRVTGKSSYDEIEEK 544
K+ K + G + +H G D+ V+ + + ++I +
Sbjct: 371 KVNK-----HAFSGGRDTIEEHRQF------GGNCDVDVSFMYLTFFLEDDDKLEQIRKD 419
Query: 545 YKNKNIHPGDFKMALAEIIKRII 613
Y + + G+ K AL E+++ +I
Sbjct: 420 YTSGAMLTGELKKALIEVLQPLI 442
>gi|2984054 (AE000754) tyrosyl tRNA synthetase [Aquifex aeolicus]
Length = 392
Score = 38.3 bits (87), Expect = 0.061
Identities = 21/62 (33%), Positives = 33/62 (52%), Gaps = 1/62 (1%)
Query: 131 VYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS-DKM 307
+YPLLQA D + DV+ GG DQ+ + + G E ++ + P++ G + KM
Sbjct: 167 IYPLLQAYDSVAIKADVEIGGTDQKFNLLIGRDIQREYGQEPQVCITLPLLVGTDGVRKM 226
Query: 308 SAS 316
S S
Sbjct: 227 SKS 229
>gi|135189|sp|P17248|SYW_BOVIN TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
>gi|68509|pir||YWBO tryptophan--tRNA ligase (EC 6.1.1.2)
- bovine >gi|825|emb|CAA37872| (X53918) tryptophan-tRNA
ligase [Bos taurus] >gi|163799 (M74074) transfer RNA-Trp
synthetase [Bos taurus]
Length = 475
Score = 38.3 bits (87), Expect = 0.061
Identities = 38/114 (33%), Positives = 51/114 (44%), Gaps = 13/114 (11%)
Query: 38 YKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQA-------LDEEYLD-VDVQF-- 187
YK + + H + T+S I +P +QA + + D DVQ
Sbjct: 252 YKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFRDRTDVQCLI 311
Query: 188 -GGVDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKH 358
+DQ F P+IGY K L + P L KMSASD S I L D+ K
Sbjct: 312 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQ 371
Query: 359 ITKKMQK 379
I K+ K
Sbjct: 372 IKTKVNK 378
>gi|165011 (M33460) eucaryotic release factor (eRF) [Oryctolagus cuniculus]
Length = 475
Score = 38.3 bits (87), Expect = 0.061
Identities = 36/114 (31%), Positives = 47/114 (40%), Gaps = 13/114 (11%)
Query: 38 YKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQFGG-------- 193
YK + + H + T+S I +P +QA F G
Sbjct: 252 YKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFHGQADIQCLI 311
Query: 194 ---VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKH 358
+DQ F P+IGY K L + P L KMSASD S I L D+ K
Sbjct: 312 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQ 371
Query: 359 ITKKMQK 379
I K+ K
Sbjct: 372 IKTKVNK 378
>gi|68510|pir||YWRBPR translation releasing factor eRF - rabbit
Length = 475
Score = 38.3 bits (87), Expect = 0.061
Identities = 36/114 (31%), Positives = 47/114 (40%), Gaps = 13/114 (11%)
Query: 38 YKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQFGG-------- 193
YK + + H + T+S I +P +QA F G
Sbjct: 252 YKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFHGQADIQCLI 311
Query: 194 ---VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKH 358
+DQ F P+IGY K L + P L KMSASD S I L D+ K
Sbjct: 312 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQDAQTKMSASDPNSSIFLTDTAKQ 371
Query: 359 ITKKMQK 379
I K+ K
Sbjct: 372 IKTKVNK 378
>gi|2851538|sp|P23612|SYW_RABIT TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
Length = 475
Score = 38.3 bits (87), Expect = 0.061
Identities = 36/114 (31%), Positives = 47/114 (40%), Gaps = 13/114 (11%)
Query: 38 YKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQFGG-------- 193
YK + + H + T+S I +P +QA F G
Sbjct: 252 YKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFHGQADIQCLI 311
Query: 194 ---VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKH 358
+DQ F P+IGY K L + P L KMSASD S I L D+ K
Sbjct: 312 PCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQ 371
Query: 359 ITKKMQK 379
I K+ K
Sbjct: 372 IKTKVNK 378
>gi|2501074|sp|Q12109|SYWC_YEAST TRYPTOPHANYL-TRNA SYNTHETASE, CYTOPLASMIC (TRYPTOPHAN--TRNA LIGASE)
(TRPRS) >gi|1077305|pir||S51901 hypothetical protein
YOL097c - yeast (Saccharomyces cerevisiae)
>gi|663256|emb|CAA88164| (Z48149) similarity with
H.sapiens tryptophanyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1419948|emb|CAA99110| (Z74839) ORF
YOL097c [Saccharomyces cerevisiae]
Length = 432
Score = 37.1 bits (84), Expect = 0.14
Identities = 37/145 (25%), Positives = 61/145 (41%), Gaps = 2/145 (1%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGL--NSDKMSASDEYSKIDLLDSDKHITK 367
+DQ F K+ Y K L + P L ++ KMSASD+ + I + D+ K I K
Sbjct: 257 IDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDDTTAIFMTDTPKQIQK 316
Query: 368 KMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGSPLRVTGKSSYDEIEEKY 547
K+ K G ++ L L P VD+ + + L+ E +KY
Sbjct: 317 KINKYAFSGGQVSADLHRELG--GNPDVDVAYQYLSFFKDDDVFLK--------ECYDKY 366
Query: 548 KNKNIHPGDFKMALAEIIKRIITPIRE 628
K+ + G+ K E ++ + +E
Sbjct: 367 KSGELLSGEMKKLCIETLQEFVKAFQE 393
>gi|3024675|sp|P56417|SYY_HELPY TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|2313900|gb|AAD07821.1| (AE000589) tyrosyl-tRNA
synthetase (tyrS) [Helicobacter pylori 26695]
Length = 402
Score = 36.4 bits (82), Expect = 0.24
Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 98 KQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLIN- 274
K+ + +YPLLQ D +D D++ GG DQ+ + G K +I
Sbjct: 162 KENRPISIVEFLYPLLQGYDSVAMDADIELGGNDQKFNLLVGRFLQRAYGLNKEQSVITM 221
Query: 275 PMIPGLNS-DKMSAS 316
P++ GL+ KMS S
Sbjct: 222 PLLEGLDGVQKMSKS 236
>gi|417846|sp|P32921|SYW_MOUSE TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
>gi|1085542|pir||S50053 tryptophan--tRNA ligase (EC
6.1.1.2) alpha-2 chain - mouse >gi|55438|emb|CAA49348|
(X69657) tryptophan--tRNA ligase [Mus musculus]
Length = 481
Score = 36.4 bits (82), Expect = 0.24
Identities = 24/62 (38%), Positives = 30/62 (47%), Gaps = 2/62 (3%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IG+ K L + P L KMSASD S I L D+ K I
Sbjct: 315 IDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKS 374
Query: 368 KMQK 379
K+ K
Sbjct: 375 KVNK 378
>gi|55436|emb|CAA49347| (X69656) tryptophan--tRNA ligase [Mus musculus]
Length = 475
Score = 36.4 bits (82), Expect = 0.24
Identities = 24/62 (38%), Positives = 30/62 (47%), Gaps = 2/62 (3%)
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNS--DKMSASDEYSKIDLLDSDKHITK 367
+DQ F P+IG+ K L + P L KMSASD S I L D+ K I
Sbjct: 315 IDQDPYFRMTRDVAPRIGHPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKS 374
Query: 368 KMQK 379
K+ K
Sbjct: 375 KVNK 378
>gi|462693|sp|P80303|NEFA_HUMAN DNA-BINDING PROTEIN NEFA PRECURSOR >gi|1363933|pir||S55272
DNA-binding protein NEFA precursor - human
>gi|436418|emb|CAA54148| (X76732) NEFA protein [Homo
sapiens] >gi|2981454 (AF052642) DNA binding protein NEFA
precursor [Homo sapiens] >gi|2981456 (AF052643) DNA
binding protein NEFA precursor [Homo sapiens]
>gi|2981458 (AF052644) DNA binding protein NEFA
precursor [Homo sapiens]
Length = 420
Score = 36.0 bits (81), Expect = 0.31
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 317 DEYSK--IDLLDSDKHITKKMQKPFCEE---GIINEGLFMLLKHIXLPIVDIKGWEIDIV 481
DEY K ID+L++DKH +K+QK EE G +++ L ++ H+ + ++K E+
Sbjct: 55 DEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEV--- 111
Query: 482 TNLGSPLRVTGKSSYDEIEE 541
LR+ K+ D +++
Sbjct: 112 ----GRLRMLIKAKLDSLQD 127
>gi|2501076|sp|P73141|SYY_SYNY3 TYROSYL-TRNA SYNTHETASE (TYROSINE--TRNA LIGASE) (TYRRS)
>gi|1652244|dbj|BAA17167| (D90904) tyrosyl tRNA
synthetase [Synechocystis sp.]
Length = 404
Score = 35.2 bits (79), Expect = 0.53
Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 5/117 (4%)
Query: 29 MDMYKXL----TITKAHDAQRAGSAVVKQTES-LLXSSIVYPLLQALDEEYLDVDVQFGG 193
+D+ K L T+T + G A Q E+ + +YPL+Q D ++ DV+ GG
Sbjct: 139 LDLNKILELLATMTVGQMLAKEGFAERFQKENPIFLHEFLYPLMQGYDSVAVNADVELGG 198
Query: 194 VDQRKIFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKIDLLDSDKHITKKM 373
DQ+ G + L+ P++ G + + + + + L + + K+
Sbjct: 199 TDQKFNIAVGRDLQRHFGKTPQFGLLLPILLGTDGQQKMSKSLNNYVGLQEDALSMYSKL 258
Query: 374 QK 379
+K
Sbjct: 259 EK 260
>gi|4155267 (AE001502) TYROSYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 402
Score = 34.0 bits (76), Expect = 1.2
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Query: 98 KQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSLPKIGYEKRIHLIN- 274
K+ + +YPLLQ D + D++ GG DQ+ + G K +I
Sbjct: 162 KENRPISIVEFLYPLLQGYDSVAMGADIELGGNDQKFNLLVGRFLQRAYGLNKEQSIITM 221
Query: 275 PMIPGLNS-DKMSAS 316
P++ GL+ KMS S
Sbjct: 222 PLLEGLDGVQKMSKS 236
>gi|4557060|gb|AAD22500|AC007154_4 (AC007154) putative chromosome-associated polypeptide, 5' partial
[Arabidopsis thaliana]
Length = 1192
Score = 34.0 bits (76), Expect = 1.2
Identities = 35/156 (22%), Positives = 72/156 (45%), Gaps = 12/156 (7%)
Query: 29 MDMYKXLTITKAHDAQRAGSAVVKQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRK 208
+D+ K + T+ ++ +R S + Q I+ ++ LDE ++D + + + +
Sbjct: 146 LDLLKEIGGTRVYEERRRESLRIMQETGNKRKQII-EVVHYLDERLRELDEEKEELRKYQ 204
Query: 209 IFIYAEKSLPKIGYEKRIHLINPMIPGLNSDKMSASDEYSKI------------DLLDSD 352
KSL Y+K +H + + + AS+E +K+ L +S
Sbjct: 205 QLDKQRKSLEYTIYDKELHDAREKLEQVEVARTKASEESTKMYDRVEKAQDDSKSLDESL 264
Query: 353 KHITKKMQKPFCEEGIINEGLFMLLKHIXLPIVDIKGWEIDIVTNLGS 496
K +TK++Q + E+ + LK +D+K ++ I N+ S
Sbjct: 265 KELTKELQTLYKEKETVEAQQTKALKKKTKLELDVKDFQDRITGNIQS 312
>gi|2501072|sp|P73655|SYW_SYNY3 TRYPTOPHANYL-TRNA SYNTHETASE (TRYPTOPHAN--TRNA LIGASE) (TRPRS)
>gi|1652781|dbj|BAA17700| (D90908) tryptophanyl-tRNA
synthetase [Synechocystis sp.]
Length = 377
Score = 32.1 bits (71), Expect = 4.6
Identities = 35/95 (36%), Positives = 50/95 (51%), Gaps = 17/95 (17%)
Query: 95 VKQTESLLXSSIVYPLLQALDEEYLDVDVQFGGVDQRKIFIYAEKSL----PKIGYEKR- 259
VKQ E++ + YP+L A D D D G DQ++ + K G E
Sbjct: 155 VKQGENVSVGLLDYPVLMAADILLYDADKVPVGEDQKQHLELTRDIVIRINDKFGREDAP 214
Query: 260 -IHLINPMIP---------GLNSDKMSASD--EYSKIDLLDSDKHITKKMQK 379
+ L P+I + KMS SD E S+I+LLD + I KK++K
Sbjct: 215 VLKLPEPLIRKEGARVMSLADGTKKMSKSDESELSRINLLDPPEMIKKKVKK 266
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 12, 1999 12:54 PM
Number of letters in database: 112,640,273
Number of sequences in database: 368,476
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125048996
Number of Sequences: 368476
Number of extensions: 2156130
Number of successful extensions: 4786
Number of sequences better than 10.0: 86
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 4736
Number of HSP's gapped (non-prelim): 46
length of query: 256
length of database: 112640273
effective HSP length: 54
effective length of query: 201
effective length of database: 92742569
effective search space: 18641256369
effective search space used: 18641256369
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 68 (30.9 bits)