BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 14-21R
(622 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
368,476 sequences; 112,640,273 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|3879009|emb|CAB03230| (Z81107) Similarity to Human adenosine ... 41 0.007
gi|1749554|dbj|BAA13835| (D89173) similar to Saccharomyces cerev... 36 0.24
gi|3806124 (AF097765) adenosine kinase [Schizophyllum commune] 35 0.41
gi|2983587 (AE000724) histidine kinase sensor protein [Aquifex a... 34 0.70
gi|1906013 (U90340) adenosine kinase [Rattus norvegicus] 34 0.70
gi|1703183|sp|P55262|ADK_CRIGR ADENOSINE KINASE (AK) (ADENOSINE ... 34 0.70
gi|2499492|sp|Q64640|ADK_RAT ADENOSINE KINASE (AK) (ADENOSINE 5'... 34 0.70
gi|3845300 (AE001422) FAD-dependent oxidoreductase (OO) [Plasmod... 33 1.6
gi|1703184|sp|P55263|ADK_HUMAN ADENOSINE KINASE (AK) (ADENOSINE ... 33 2.0
gi|1906009 (U90338) adenosine kinase long form [Homo sapiens] 33 2.0
gi|1224125 (U50196) adenosine kinase [Homo sapiens] >gi|4501943|... 33 2.0
gi|1906011 (U90339) adenosine kinase short form [Homo sapiens] 33 2.0
gi|3915563|sp|O32153|YURL_BACSU HYPOTHETICAL SUGAR KINASE IN HOM... 32 3.5
gi|1353386 (U33936) adenosine kinase [Homo sapiens] 32 4.6
gi|4469011|emb|CAB38272| (AL035602) carbohydrate kinase-like pro... 32 4.6
gi|1703185|sp|P55264|ADK_MOUSE ADENOSINE KINASE (AK) (ADENOSINE ... 31 6.0
gi|1217998 (U26589) adenosine kinase [Mus musculus] 31 6.0
gi|1708626|sp|P50845|KDGK_BACSU 2-DEHYDRO-3-DEOXYGLUCONOKINASE (... 31 6.0
>gi|3879009|emb|CAB03230| (Z81107) Similarity to Human adenosine kinase (SW:P55263); cDNA EST
EMBL:Z14851 comes from this gene; cDNA EST EMBL:M89406
comes from this gene; cDNA EST EMBL:M89090 comes from
this gene; cDNA EST EMBL:M89195 comes from this ge...
Length = 342
Score = 41.0 bits (94), Expect = 0.007
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 8 NSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEGKT 184
++K + ++ T G + +I + + + ++ +++I T GAGDAF G L FI+GK
Sbjct: 253 STKPRLVVFTQGPEPVIVVEGDKVTEFPVTRLPKEEIVDTNGAGDAFVGGFLSQFIQGKG 312
Query: 185 SKNIVENGYKYSYEWIIKK 241
+ V G Y+ + IIKK
Sbjct: 313 VEASVTCG-SYAAQEIIKK 330
>gi|1749554|dbj|BAA13835| (D89173) similar to Saccharomyces cerevisiae hypothetical 36.4KD
protein in SOD1-CPA2 intergenic region, SWISS-PROT
Accession Number P47143 [Schizosaccharomyces pombe]
>gi|3184089|emb|CAA19345| (AL023781) adenosine kinase
[Schizosaccharomyces pombe]
Length = 351
Score = 36.0 bits (81), Expect = 0.24
Identities = 21/77 (27%), Positives = 37/77 (47%), Gaps = 1/77 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
++ +T+ ++ T G I + + KP ++ ++I T GAGDAF G + A +G
Sbjct: 257 VNKKRTRVVVITQGADATIVAKDGKVTTYKPNRVPSEEIVDTNGAGDAFAGGFIAALSQG 316
Query: 179 KTSKNIVENGYKYSYEWI 232
+ V G+ E I
Sbjct: 317 QGIDYAVTLGHWLGQECI 334
>gi|3806124 (AF097765) adenosine kinase [Schizophyllum commune]
Length = 344
Score = 35.2 bits (79), Expect = 0.41
Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 4/68 (5%)
Query: 11 SKTKFLICTDGDKDIIYTDN---NNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
++ + +I T G ++ + ++ + K K+ E +I T GAGDAF G L A + G
Sbjct: 252 ARPRVVIFTHGAEETVVVNSAEPGRVRTFKVDKLAEGEIVDTNGAGDAFAGGFLGALVAG 311
Query: 179 KTSKNIVENGYK 214
+ + VE G+K
Sbjct: 312 RELDDSVEAGHK 323
>gi|2983587 (AE000724) histidine kinase sensor protein [Aquifex aeolicus]
Length = 646
Score = 34.4 bits (77), Expect = 0.70
Identities = 24/76 (31%), Positives = 34/76 (44%)
Query: 41 GDKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEGKTSKNIVENGYKYS 220
G K I+Y + IY L P + Y K++ G +F G+L I + K + EN Y
Sbjct: 224 GGKWIVYAEEPLIYVLSPLENYRKEVILAGLFTSFSGGILCLIIIIRIFKPL-ENFKDYV 282
Query: 221 YEWIIKKTKEYKDNLK 268
W + E NLK
Sbjct: 283 VSWAKENLSE---NLK 295
>gi|1906013 (U90340) adenosine kinase [Rattus norvegicus]
Length = 361
Score = 34.4 bits (77), Expect = 0.70
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDG-DKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I+ T N+ + + E+ + T GAGDAF G L +
Sbjct: 270 VNSKRQRTVIFTQGRDDTIVATGNDVTAFPVLDQNQEEIVDTNGAGDAFVGGFLSQLVSN 329
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 330 KPLTECIRAGH-YAASVIIRRT 350
>gi|1703183|sp|P55262|ADK_CRIGR ADENOSINE KINASE (AK) (ADENOSINE 5'-PHOSPHOTRANSFERASE) >gi|1217996
(U26588) Method: conceptual translation supplied by
author.; purine salvage pathway enzyme [Cricetulus
griseus]
Length = 334
Score = 34.4 bits (77), Expect = 0.70
Identities = 21/81 (25%), Positives = 38/81 (45%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + ++ T G D + N + +K+I T GAGDAF G L +
Sbjct: 243 VNSKRPRTVVFTQGRDDTVVATENEVMAFAVLDQNQKEIIDTNGAGDAFVGGFLSQLVYN 302
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 303 KPLTECIRAGH-YAASVIIRRT 323
>gi|2499492|sp|Q64640|ADK_RAT ADENOSINE KINASE (AK) (ADENOSINE 5'-PHOSPHOTRANSFERASE) >gi|1373230
(U57042) adenosine kinase [Rattus rattus]
Length = 334
Score = 34.4 bits (77), Expect = 0.70
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDG-DKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I+ T N+ + + E+ + T GAGDAF G L +
Sbjct: 243 VNSKRQRTVIFTQGRDDTIVATGNDVTAFPVLDQNQEEIVDTNGAGDAFVGGFLSQLVSN 302
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 303 KPLTECIRAGH-YAASVIIRRT 323
>gi|3845300 (AE001422) FAD-dependent oxidoreductase (OO) [Plasmodium
falciparum]
Length = 426
Score = 33.2 bits (74), Expect = 1.6
Identities = 30/93 (32%), Positives = 47/93 (50%), Gaps = 7/93 (7%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKI-------YEKDIFTCGAGDAFCAGVL 160
I N+ K+ +C D D+ Y + N Y KPK+I YEK+ C D + +
Sbjct: 206 IKNNYHKYYLC-DNKYDVQYKVSGNNYLKKPKEIHTNSFLDYEKEFGYC--FDTSYSNIE 262
Query: 161 DAFIEGKTSKNIVENGYKYSYEWIIKKTKEYKDNLKKSKY 280
+A++ N + N YKY + +I K+Y +L S Y
Sbjct: 263 EAYV---LWSNYLLN-YKYGKDLVI-NYKQYDTHLSTSMY 297
>gi|1703184|sp|P55263|ADK_HUMAN ADENOSINE KINASE (AK) (ADENOSINE 5'-PHOSPHOTRANSFERASE)
Length = 334
Score = 32.8 bits (73), Expect = 2.0
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I + + +K+I T GAGDAF G L +
Sbjct: 243 MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSD 302
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 303 KPLTECIRAGH-YAASIIIRRT 323
>gi|1906009 (U90338) adenosine kinase long form [Homo sapiens]
Length = 362
Score = 32.8 bits (73), Expect = 2.0
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I + + +K+I T GAGDAF G L +
Sbjct: 271 MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSD 330
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 331 KPLTECIRAGH-YAASIIIRRT 351
>gi|1224125 (U50196) adenosine kinase [Homo sapiens]
>gi|4501943|ref|NP_001114.1|pADK| adenosine kinase
Length = 345
Score = 32.8 bits (73), Expect = 2.0
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I + + +K+I T GAGDAF G L +
Sbjct: 254 MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSD 313
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 314 KPLTECIRAGH-YAASIIIRRT 334
>gi|1906011 (U90339) adenosine kinase short form [Homo sapiens]
Length = 345
Score = 32.8 bits (73), Expect = 2.0
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I + + +K+I T GAGDAF G L +
Sbjct: 254 MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSD 313
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 314 KPLTECIRAGH-YAASIIIRRT 334
>gi|3915563|sp|O32153|YURL_BACSU HYPOTHETICAL SUGAR KINASE IN HOM-MRGA INTERGENIC REGION
>gi|2635754|emb|CAB15247| (Z99120) similar to opine
catabolism [Bacillus subtilis]
Length = 284
Score = 32.1 bits (71), Expect = 3.5
Identities = 20/50 (40%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 20 KFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAF 169
K + T G + I + + +Y+ + I E DI T GAGD+F AG L AF
Sbjct: 190 KMVCMTRGGQGAILSAGDRVYH---QPIVEADIIDTLGAGDSFIAGFLTAF 237
>gi|1353386 (U33936) adenosine kinase [Homo sapiens]
Length = 334
Score = 31.7 bits (70), Expect = 4.6
Identities = 21/81 (25%), Positives = 38/81 (45%), Gaps = 1/81 (1%)
Query: 2 ISNSKTKFLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIF-TCGAGDAFCAGVLDAFIEG 178
+++ + + +I T G D I + + +++I T GAGDAF G L +
Sbjct: 243 MNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQREIIDTNGAGDAFVGGFLSQLVSD 302
Query: 179 KTSKNIVENGYKYSYEWIIKKT 244
K + G+ Y+ II++T
Sbjct: 303 KPLTECIRAGH-YAASIIIRRT 323
>gi|4469011|emb|CAB38272| (AL035602) carbohydrate kinase-like protein [Arabidopsis thaliana]
Length = 406
Score = 31.7 bits (70), Expect = 4.6
Identities = 17/52 (32%), Positives = 23/52 (43%)
Query: 23 FLICTDGDKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEG 178
F+ TDG Y+ P D TCGAGDA+ +G+L + G
Sbjct: 304 FVSVTDGINGSYIGVKGEAIYIPPSPCVPVD--TCGAGDAYASGILYGILRG 353
>gi|1703185|sp|P55264|ADK_MOUSE ADENOSINE KINASE (AK) (ADENOSINE 5'-PHOSPHOTRANSFERASE)
Length = 279
Score = 31.3 bits (69), Expect = 6.0
Identities = 20/67 (29%), Positives = 32/67 (46%)
Query: 44 DKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEGKTSKNIVENGYKYSY 223
D I+ T N+ + + E+ + T GAGDAF G L + K + G+ Y+
Sbjct: 203 DDTIVATGNDVTAFPVLDENQEEIVDTNGAGDAFVGGFLSQLVSNKPLTECIRAGH-YAA 261
Query: 224 EWIIKKT 244
II++T
Sbjct: 262 SVIIRRT 268
>gi|1217998 (U26589) adenosine kinase [Mus musculus]
Length = 271
Score = 31.3 bits (69), Expect = 6.0
Identities = 20/67 (29%), Positives = 32/67 (46%)
Query: 44 DKDIIYTDNNNIYYLKPKKIYEKDIFTCGAGDAFCAGVLDAFIEGKTSKNIVENGYKYSY 223
D I+ T N+ + + E+ + T GAGDAF G L + K + G+ Y+
Sbjct: 195 DDTIVATGNDVTAFPVLDENQEEIVDTNGAGDAFVGGFLSQLVSNKPLTECIRAGH-YAA 253
Query: 224 EWIIKKT 244
II++T
Sbjct: 254 SVIIRRT 260
>gi|1708626|sp|P50845|KDGK_BACSU 2-DEHYDRO-3-DEOXYGLUCONOKINASE (2-KETO-3-DEOXYGLUCONOKINASE)
(3-DEOXY-2-OXO-D-GLUCONATE KINASE) (KDG KINASE)
>gi|1146189 (L47838) 2-keto-3-deoxygluconate kinase
[Bacillus subtilis] >gi|2634630|emb|CAB14128| (Z99115)
2-keto-3-deoxygluconate kinase [Bacillus subtilis]
Length = 324
Score = 31.3 bits (69), Expect = 6.0
Identities = 12/34 (35%), Positives = 21/34 (61%)
Query: 107 EKDIFTCGAGDAFCAGVLDAFIEGKTSKNIVENG 208
++ + T GAGD F GV+ ++G + K+ V+ G
Sbjct: 251 DRVVDTVGAGDGFAVGVISGILDGLSYKDAVQRG 284
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 12, 1999 12:54 PM
Number of letters in database: 112,640,273
Number of sequences in database: 368,476
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84182340
Number of Sequences: 368476
Number of extensions: 1366539
Number of successful extensions: 3329
Number of sequences better than 10.0: 36
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3323
Number of HSP's gapped (non-prelim): 22
length of query: 207
length of database: 112640273
effective HSP length: 53
effective length of query: 153
effective length of database: 93111045
effective search space: 14245989885
effective search space used: 14245989885
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 67 (30.5 bits)