BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 13VII-16F
(808 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
369,800 sequences; 113,023,754 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|3135992|emb|CAA19053| (AL023589) histone deacetylase [Schizos... 299 2e-80
gi|2827430 (AF043328) histone deacetylase 1 [Gallus gallus] 293 8e-79
gi|3023929|sp|P56517|HDA1_CHICK HISTONE DEACETYLASE 1 (HD1) >gi|... 293 8e-79
gi|2498443|sp|Q13547|HDA1_HUMAN HISTONE DEACETYLASE 1 (HD1) >gi|... 290 7e-78
gi|2498444|sp|O09106|HDA1_MOUSE HISTONE DEACETYLASE 1 (HD1) >gi|... 290 7e-78
gi|2347180 (U80780) putative histone deacetylase [Mus musculus] 290 7e-78
gi|3023928|sp|O42227|HD12_XENLA PROBABLE HISTONE DEACETYLASE 1-2... 289 1e-77
gi|3659524 (AF086715) putative histone deacetylase [Drosophila m... 289 1e-77
gi|3023958|sp|Q94517|HDAC_DROME PROBABLE HISTONE DEACETYLASE (HD... 287 6e-77
gi|3023931|sp|P56519|HDA2_CHICK HISTONE DEACETYLASE 2 (HD2) >gi|... 286 1e-76
gi|417699|sp|P32561|RPD3_YEAST HISTONE DEACETYLASE RPD3 (TRANSCR... 285 2e-76
gi|1665723|dbj|BAA08909| (D50405) RPD3 protein [Homo sapiens] 285 3e-76
gi|2583090 (AF026949) putative histone deacetylase HDAC1 [Drosop... 285 3e-76
gi|3023930|sp|P56518|HDA1_STRPU HISTONE DEACETYLASE 1 (HD1) >gi|... 283 9e-76
gi|3023937|sp|Q91695|HD11_XENLA PROBABLE HISTONE DEACETYLASE 1-1... 281 3e-75
gi|3023934|sp|P70288|HDA2_MOUSE HISTONE DEACETYLASE 2 (HD2) (YY1... 281 3e-75
gi|4557641|oth|NP_001518|PHDAC2 histone deacetylase 2 >gi|302393... 281 4e-75
gi|3023945|sp|O22446|HDAC_ARATH HISTONE DEACETYLASE (HD) >gi|231... 275 2e-73
gi|4467119|emb|CAB37553| (AL035538) Histone deacetylase [Arabido... 275 2e-73
gi|4193320 (AF045473) histone deacetylase [Zea mays] 273 1e-72
gi|4545130|gb|AAD22407|AF091326_1 (AF091326) histone deacetylase... 271 4e-72
gi|3023947|sp|P56521|HDAC_MAIZE PROBABLE HISTONE DEACETYLASE (RP... 269 2e-71
gi|3023932|sp|P56520|HDA3_CHICK HISTONE DEACETYLASE 3 (HD3) >gi|... 264 5e-70
gi|4504363|oth|NP_003874|PHDAC3 UNKNOWN >gi|2326173 (U66914) his... 264 6e-70
gi|3023926|sp|O17695|HDA1_CAEEL PROBABLE HISTONE DEACETYLASE C53... 263 1e-69
gi|2661170 (U75696) RPD3-2A [Homo sapiens] 262 2e-69
gi|3639054 (AF074881) histone deacetylase 3 [Mus musculus] >gi|3... 262 2e-69
gi|3334210|sp|O15379|HDA3_HUMAN HISTONE DEACETYLASE 3 (HD3) >gi|... 262 2e-69
gi|2654535 (AF005482) histone deacetylase-3C [Homo sapiens] 262 2e-69
gi|3878853|emb|CAB03224| (Z81106) similar to Histone deacetylase... 257 8e-68
gi|3982757 (AF071559) histone deacetylase dHDAC3 [Drosophila mel... 243 8e-64
gi|1723948|sp|P53096|HOS2_YEAST PROBABLE HISTONE DEACETYLASE HOS... 238 3e-62
gi|2995806 (AF053139) histone deacetylase 3 [Homo sapiens] 233 9e-61
gi|3024397|sp|O13298|PHD1_SCHPO PROBABLE HISTONE DEACETYLASE PHD... 230 8e-60
gi|1177634|emb|CAA62950| (X91837) putative transcriptional regul... 227 7e-59
gi|1176665|sp|Q09440|HDA2_CAEEL PUTATIVE HISTONE DEACETYLASE C08... 201 5e-51
gi|3639056 (AF074882) histone deacetylase 3 [Mus musculus] 147 7e-35
gi|2833221|sp|Q12214|HOS1_YEAST HOS1 PROTEIN >gi|1084790|pir||S5... 108 5e-23
gi|2983524 (AE000719) acetoin utilization protein [Aquifex aeoli... 100 2e-20
gi|3024859|sp|O30107|Y130_ARCFU HYPOTHETICAL PROTEIN AF0130 >gi|... 93 2e-18
gi|3023253|sp|Q56195|ACUC_STAXY ACETOIN UTILIZATION ACUC PROTEIN... 92 6e-18
gi|1730711|sp|P53973|HDA1_YEAST HISTONE DEACETYLASE HDA1 >gi|213... 86 3e-16
gi|3024905|sp|Q57955|Y535_METJA HYPOTHETICAL PROTEIN MJ0535 >gi|... 85 6e-16
gi|2984320 (AE000773) acetoin utilization protein [Aquifex aeoli... 85 7e-16
gi|728801|sp|P39067|ACUC_BACSU ACETOIN UTILIZATION ACUC PROTEIN ... 83 3e-15
gi|3257687|dbj|BAA30370| (AP000005) 335aa long hypothetical prot... 83 3e-15
gi|3023933|sp|P56523|HDA1_SCHPO HYPOTHETICAL 76.8 KD PROTEIN IN ... 80 1e-14
gi|3024889|sp|P56524|Y288_HUMAN HYPOTHETICAL PROTEIN KIAA0288 (H... 76 2e-13
gi|2435529 (AF026202) contains similarity to S. cerevisiae trans... 76 2e-13
gi|4490314|emb|CAB38805| (AL035678) putative protein [Arabidopsi... 75 6e-13
gi|4101722 (AF006602) histone deacetylase mHDA1 [Mus musculus] 73 3e-12
gi|3043724|dbj|BAA25526| (AB011172) KIAA0600 protein [Homo sapiens] 72 4e-12
gi|3170182 (AF039691) antigen NY-CO-9 [Homo sapiens] 72 4e-12
gi|3024979|sp|O27262|YB94_METTH HYPOTHETICAL PROTEIN MTH1194 >gi... 71 1e-11
gi|3881091|emb|CAA21669| (AL032644) similar to Histone deacetyla... 68 8e-11
gi|3025216|sp|Q20296|YLFN_CAEEL HYPOTHETICAL 89.8 KD PROTEIN F41... 68 8e-11
gi|4455131|gb|AAD21090| (AF129433) histone deacetylase HDA2 [Dro... 68 1e-10
gi|4165861 (AF006603) histone deacetylase mHDA2 [Mus musculus] 64 9e-10
gi|3024891|sp|P72702|Y245_SYNY3 HYPOTHETICAL 33.6 KD PROTEIN SLR... 64 9e-10
gi|3776071|emb|CAA09893| (AJ011972) histone deacetylase-like pro... 64 9e-10
gi|4240291|dbj|BAA74924| (AB020708) KIAA0901 protein [Homo sapiens] 64 9e-10
gi|3023317|sp|Q48935|APHA_MYCRA ACETYLPOLYAMINE AMINOHYDROLASE >... 57 1e-07
gi|669045|emb|CAA78369| (Z13965) Portion of hypothetical protein... 57 1e-07
gi|669044|emb|CAA78368| (Z13965) Portion of hypothetical protein... 57 1e-07
gi|140712|sp|P28606|YGLA_SYNP2 HYPOTHETICAL 34.1 KD PROTEIN IN G... 57 1e-07
gi|854536|emb|CAA86368| (Z46259) RPD3 gene [Saccharomyces cerevi... 51 1e-05
gi|3979814|emb|CAA90401| (Z50070) similar to transcriptional reg... 38 0.086
gi|2315555 (AF016657) C16C4.7 [Caenorhabditis elegans] 34 0.97
gi|1076557|pir||S54157 extensin-like protein - cowpea (fragment) 33 2.9
gi|2494726|sp|Q91513|PRLR_ORENI PROLACTIN RECEPTOR PRECURSOR (PR... 32 6.4
gi|3880316|emb|CAB03443| (Z81133) Similarity to C.elegans mechan... 31 8.4
gi|133320|sp|P22138|RPA2_YEAST DNA-DIRECTED RNA POLYMERASE I 135... 31 8.4
>gi|3135992|emb|CAA19053| (AL023589) histone deacetylase [Schizosaccharomyces pombe]
>gi|4159997 (AF064206) putative histone deacetylase
[Schizosaccharomyces pombe]
Length = 405
Score = 299 bits (757), Expect = 2e-80
Identities = 133/220 (60%), Positives = 171/220 (77%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEE FYT+DRVM+ F FPGTG + DTGI GKNYAVNVPL
Sbjct: 166 RVLYIDIDVHHGDGVEEFFYTTDRVMTCSFHKFGEYFPGTGHIKDTGIGTGKNYAVNVPL 225
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE +F V+ ++ F+P ++LQCG DSL+GDRLGCFNLS KGH+ CV V
Sbjct: 226 RDGIDDESYESVFKPVISHIMQWFRPEAVILQCGTDSLAGDRLGCFNLSMKGHSMCVDFV 285
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PM+ +GGGGYT+RNV+R W YETG++ G +L E++PYN+Y +++GPDYK+NVLS
Sbjct: 286 KSFNLPMICVGGGGYTVRNVARVWTYETGLLAGEELDENLPYNDYLQYYGPDYKLNVLSN 345
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAF 135
NM+N+N R+YLD+I + ENLR++ PSVQ+ P F
Sbjct: 346 NMENHNTRQYLDSITSEIIENLRNLSFAPSVQMHKTPGDF 385
>gi|2827430 (AF043328) histone deacetylase 1 [Gallus gallus]
Length = 480
Score = 293 bits (743), Expect = 8e-79
Identities = 141/244 (57%), Positives = 177/244 (71%), Gaps = 6/244 (2%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + TF+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVISKVMETFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFI------DCESDEKLLWSKF 93
NM N N +YL+ I + + ENLR + P VQ+ IP + + E D + S
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQPIPEDAVQEDSGDEEEEDPEKRISIR 408
Query: 92 KEDKGIDSDE 63
DK I DE
Sbjct: 409 NSDKRISCDE 418
>gi|3023929|sp|P56517|HDA1_CHICK HISTONE DEACETYLASE 1 (HD1) >gi|2791684 (AF039751) histone
deacetylase-1; HD-1 [Gallus gallus] >gi|2829214
(AF044169) erythrocyte histone deacetylase [Gallus
gallus]
Length = 480
Score = 293 bits (743), Expect = 8e-79
Identities = 141/244 (57%), Positives = 177/244 (71%), Gaps = 6/244 (2%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + TF+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVISKVMETFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFI------DCESDEKLLWSKF 93
NM N N +YL+ I + + ENLR + P VQ+ IP + + E D + S
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQPIPEDAVQEDSGDEEEEDPEKRISIR 408
Query: 92 KEDKGIDSDE 63
DK I DE
Sbjct: 409 NSDKRISCDE 418
>gi|2498443|sp|Q13547|HDA1_HUMAN HISTONE DEACETYLASE 1 (HD1) >gi|1277084 (U50079) histone
deacetylase HD1 [Homo sapiens]
Length = 482
Score = 290 bits (735), Expect = 7e-78
Identities = 135/228 (59%), Positives = 170/228 (74%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ IP I ES ++
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDE 396
>gi|2498444|sp|O09106|HDA1_MOUSE HISTONE DEACETYLASE 1 (HD1) >gi|1771286|emb|CAA66870| (X98207)
histone deacetylase [Mus musculus]
Length = 482
Score = 290 bits (735), Expect = 7e-78
Identities = 135/228 (59%), Positives = 170/228 (74%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ IP I ES ++
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDE 396
>gi|2347180 (U80780) putative histone deacetylase [Mus musculus]
Length = 482
Score = 290 bits (735), Expect = 7e-78
Identities = 135/228 (59%), Positives = 170/228 (74%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ IP I ES ++
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDE 396
>gi|3023928|sp|O42227|HD12_XENLA PROBABLE HISTONE DEACETYLASE 1-2 (HD1) (RPD3 HOMOLOG) >gi|2444430
(AF020658) deacetylase [Xenopus laevis]
Length = 480
Score = 289 bits (733), Expect = 1e-77
Identities = 134/228 (58%), Positives = 170/228 (73%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVMSV F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVVYIDIDIHHGDGVEEAFYTTDRVMSVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCGADSLSGDRLGCFNL+ KGHA CV+ +
Sbjct: 229 RDGIDDESYEAIFKPVMTKVMEMFQPSAVVLQCGADSLSGDRLGCFNLTIKGHAKCVEFI 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
++N+PML+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KTFNLPMLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ IP + +S E+
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDSVHDDSGEE 396
>gi|3659524 (AF086715) putative histone deacetylase [Drosophila melanogaster]
Length = 521
Score = 289 bits (733), Expect = 1e-77
Identities = 138/244 (56%), Positives = 175/244 (71%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN+PL
Sbjct: 167 RVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPL 226
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DG+DD++YE IF ++ K + TF+P +VLQCGADSL+GDRLGCFNL+ KGH CV+ V
Sbjct: 227 RDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFV 286
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
YN+P L++GGGGYTIRNVSR W YET V V++ ++PYN+YFE+FGPD+K+++
Sbjct: 287 KKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPS 346
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEKLLWSKFKEDKGI 75
NM N N +YL+ I + ENLR + P VQI IP I+ ESD+ EDK +
Sbjct: 347 NMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDD--------EDK-V 397
Query: 74 DSDE 63
D D+
Sbjct: 398 DKDD 401
>gi|3023958|sp|Q94517|HDAC_DROME PROBABLE HISTONE DEACETYLASE (HD) (DRPD3) >gi|1666637|emb|CAA70455|
(Y09258) histone deacetylase [Drosophila melanogaster]
Length = 520
Score = 287 bits (727), Expect = 6e-77
Identities = 137/244 (56%), Positives = 174/244 (71%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN+PL
Sbjct: 166 RVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPL 225
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DG+DD++YE IF ++ K + TF+P +VLQCGADSL+GDRLGCFNL+ KGH CV+ V
Sbjct: 226 RDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFV 285
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
YN+P L++GGGGYTIR VSR W YET V V++ ++PYN+YFE+FGPD+K+++
Sbjct: 286 KKYNLPFLMVGGGGYTIRKVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPS 345
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEKLLWSKFKEDKGI 75
NM N N +YL+ I + ENLR + P VQI IP I+ ESD+ EDK +
Sbjct: 346 NMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDD--------EDK-V 396
Query: 74 DSDE 63
D D+
Sbjct: 397 DKDD 400
>gi|3023931|sp|P56519|HDA2_CHICK HISTONE DEACETYLASE 2 (HD2) >gi|2791686 (AF039752) histone
deacetylase-2; HD-2 [Gallus gallus]
Length = 488
Score = 286 bits (724), Expect = 1e-76
Identities = 128/228 (56%), Positives = 172/228 (75%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V ++M N FPGTG L D G KGK YAVN P+
Sbjct: 170 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSEVSMVNNFPGTGDLRDIGAGKGKYYAVNFPM 229
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESY IF ++ K + ++P+ +VLQCGADSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 230 RDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVV 289
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
++N+P+L+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 290 KTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPS 349
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +Y++ I + + ENLR + P VQ+ IP + +S ++
Sbjct: 350 NMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDE 397
>gi|417699|sp|P32561|RPD3_YEAST HISTONE DEACETYLASE RPD3 (TRANSCRIPTIONAL REGULATORY PROTEIN RPD3)
>gi|83513|pir||S22284 transcription regulator RPD3 -
yeast (Saccharomyces cerevisiae) >gi|238962|bbs|66439
(S66438) RPD3 [Saccharomyces cerevisiae, Peptide, 433
aa] [Saccharomyces cerevisiae] >gi|642338|emb|CAA58228|
(X83226) global transcriptional regulator [Saccharomyces
cerevisiae] >gi|1302451|emb|CAA96263| (Z71606) ORF
YNL330c [Saccharomyces cerevisiae]
Length = 433
Score = 285 bits (722), Expect = 2e-76
Identities = 128/217 (58%), Positives = 164/217 (74%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEEAFYT+DRVM+ F FPGTG L D G+ GKNYAVNVPL
Sbjct: 179 RVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGAGKNYAVNVPL 238
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDD +Y +F V++K + ++P+ +VLQCG DSLSGDRLGCFNLS +GHANCV V
Sbjct: 239 RDGIDDATYRSVFEPVIKKIMEWYQPSAVVLQCGGDSLSGDRLGCFNLSMEGHANCVNYV 298
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+ IPM+V+GGGGYT+RNV+RTW +ETG++ V L +D+PYNEY+E++GPDYK++V
Sbjct: 299 KSFGIPMMVVGGGGYTMRNVARTWCFETGLLNNVVLDKDLPYNEYYEYYGPDYKLSVRPS 358
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
NM N N +YLD ++ + NL + PSVQ+ P
Sbjct: 359 NMFNVNTPEYLDKVMTNIFANLENTKYAPSVQLNHTP 395
>gi|1665723|dbj|BAA08909| (D50405) RPD3 protein [Homo sapiens]
Length = 482
Score = 285 bits (721), Expect = 3e-76
Identities = 134/228 (58%), Positives = 169/228 (73%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 169 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCG+DSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 229 RDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFV 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+PML+LGGGGYTIRNV+R YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KSFNLPMLMLGGGGYTIRNVARCRTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ IP I ES ++
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDE 396
>gi|2583090 (AF026949) putative histone deacetylase HDAC1 [Drosophila
melanogaster]
Length = 522
Score = 285 bits (721), Expect = 3e-76
Identities = 138/244 (56%), Positives = 175/244 (71%), Gaps = 1/244 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN+PL
Sbjct: 167 RVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPL 226
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DG+DD++YE IF ++ K + TF+P +VLQCGADSL+GDRLGCFNL+ KGH CV+ V
Sbjct: 227 RDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFV 286
Query: 434 MSYNIP-MLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLS 258
YN+P ++V+GGGGYTIR VSR W YET V V++ ++PYN+YFE+FGPD+K+++
Sbjct: 287 KKYNLPFLMVVGGGGYTIRKVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISP 346
Query: 257 GNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEKLLWSKFKEDKG 78
NM N N +YL+ I + ENLR V P VQI IP I+ ESD+ EDK
Sbjct: 347 SNMTNQNTSEYLEKIKNRLFENLRMVPHAPGVQIQAIPEDAINDESDD--------EDK- 397
Query: 77 IDSDE 63
+D D+
Sbjct: 398 VDKDD 402
>gi|3023930|sp|P56518|HDA1_STRPU HISTONE DEACETYLASE 1 (HD1) >gi|2654077|gb|AAB87685| (AF032919)
histone deacetylase [Strongylocentrotus purpuratus]
Length = 576
Score = 283 bits (717), Expect = 9e-76
Identities = 130/226 (57%), Positives = 166/226 (72%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN PL
Sbjct: 168 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPL 227
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESY+ IF ++ K + ++P+ I LQCGADSLSGDRLGCFNL+ KGHA CV+ +
Sbjct: 228 RDGIDDESYDKIFKPIMCKVMEMYQPSAICLQCGADSLSGDRLGCFNLTLKGHAKCVEFM 287
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
YN+P+L++GGGGYTIRNV+R W YET GV++ ++PYN+YFE+FGPD+K+++
Sbjct: 288 KQYNLPLLLMGGGGYTIRNVARCWTYETSTALGVEIANELPYNDYFEYFGPDFKLHISPS 347
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESD 117
NM N N +YLD I + EN+R + P VQ+ IP I +SD
Sbjct: 348 NMTNQNTGEYLDKIKTRLYENMRMIPHAPGVQMQPIPEDAIPDDSD 393
>gi|3023937|sp|Q91695|HD11_XENLA PROBABLE HISTONE DEACETYLASE 1-1 (HD1) (MATERNALLY-EXPRESSED
HISTONE DEACETYLASE) (HDM) (AB21)
>gi|2120022|pir||S60381 RPD3 protein homolog - African
clawed frog >gi|602098|emb|CAA55211| (X78454) yeast RPD3
homologue [Xenopus laevis]
Length = 480
Score = 281 bits (712), Expect = 3e-75
Identities = 130/228 (57%), Positives = 168/228 (73%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN L
Sbjct: 169 RVVYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYAL 228
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESYE IF V+ K + F+P+ +VLQCGADSLSGDRLGCFNL+ KGHA CV+ +
Sbjct: 229 RDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGADSLSGDRLGCFNLTIKGHAKCVEFI 288
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
++N+P+L+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 289 KTFNLPLLMLGGGGYTIRNVARCWTYETAVALDSEIPNELPYNDYFEYFGPDFKLHISPS 348
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +YL+ I + + ENLR + P VQ+ + I +S E+
Sbjct: 349 NMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAVAEDSIHDDSGEE 396
>gi|3023934|sp|P70288|HDA2_MOUSE HISTONE DEACETYLASE 2 (HD2) (YY1 TRANSCRIPTION FACTOR BINDING
PROTEIN) >gi|1667396 (U31758) transcriptional regulator
homolog RPD3 [Mus musculus]
Length = 488
Score = 281 bits (712), Expect = 3e-75
Identities = 126/228 (55%), Positives = 168/228 (73%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN P+
Sbjct: 170 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPM 229
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGIDDESY IF ++ K + ++P+ +VLQCGADSLSGDRLGCFNL+ KGHA CV+
Sbjct: 230 RDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVA 289
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
++N+P+L+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 290 KTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPS 349
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +Y++ I + + ENLR + P VQ+ IP + +S ++
Sbjct: 350 NMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDE 397
>gi|4557641|oth|NP_001518|PHDAC2 histone deacetylase 2 >gi|3023939|sp|Q92769|HDA2_HUMAN HISTONE
DEACETYLASE 2 (HD2) >gi|1667394 (U31814) transcriptional
regulator homolog RPD3 [Homo sapiens]
Length = 488
Score = 281 bits (711), Expect = 4e-75
Identities = 127/228 (55%), Positives = 168/228 (72%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGVEEAFYT+DRVM+V F FPGTG L D G KGK YAVN P+
Sbjct: 170 RVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPM 229
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
DGIDDESY IF ++ K + ++P+ +VLQCGADSLSGDRLGCFNL+ KGHA CV+ V
Sbjct: 230 CDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVV 289
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
++N+P+L+LGGGGYTIRNV+R W YET V ++P ++PYN+YFE+FGPD+K+++
Sbjct: 290 KTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPS 349
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEK 111
NM N N +Y++ I + + ENLR + P VQ+ IP + +S ++
Sbjct: 350 NMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDE 397
>gi|3023945|sp|O22446|HDAC_ARATH HISTONE DEACETYLASE (HD) >gi|2318131 (AF014824) histone deacetylase
[Arabidopsis thaliana]
Length = 501
Score = 275 bits (697), Expect = 2e-73
Identities = 127/227 (55%), Positives = 163/227 (70%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+Y+DID+HHGDGVEEAFY +DRVM+V F + FPGTG + D G GK Y++NVPL
Sbjct: 177 RVLYVDIDIHHGDGVEEAFYATDRVMTVSFHKFGDYFPGTGHIQDIGYGSGKYYSLNVPL 236
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
DGIDDESY +F ++ K + F+P +VLQCGADSLSGDRLGCFNLS KGHA CVK +
Sbjct: 237 DDGIDDESYHLLFKPIMGKVMEIFRPGAVVLQCGADSLSGDRLGCFNLSIKGHAECVKFM 296
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+P+L+LGGGGYTIRNV+R W YETGV GV++ + +P +EY+E+FGPDY ++V
Sbjct: 297 RSFNVPLLLLGGGGYTIRNVARCWCYETGVALGVEVEDKMPEHEYYEYFGPDYTLHVAPS 356
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDE 114
NM+N N R+ L+ I + NL + PSV + PP E DE
Sbjct: 357 NMENKNSRQMLEEIRNDLLHNLSKLQHAPSVPFQERPPDTETPEVDE 403
>gi|4467119|emb|CAB37553| (AL035538) Histone deacetylase [Arabidopsis thaliana]
Length = 501
Score = 275 bits (697), Expect = 2e-73
Identities = 127/227 (55%), Positives = 163/227 (70%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+Y+DID+HHGDGVEEAFY +DRVM+V F + FPGTG + D G GK Y++NVPL
Sbjct: 177 RVLYVDIDIHHGDGVEEAFYATDRVMTVSFHKFGDYFPGTGHIQDIGYGSGKYYSLNVPL 236
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
DGIDDESY +F ++ K + F+P +VLQCGADSLSGDRLGCFNLS KGHA CVK +
Sbjct: 237 DDGIDDESYHLLFKPIMGKVMEIFRPGAVVLQCGADSLSGDRLGCFNLSIKGHAECVKFM 296
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+P+L+LGGGGYTIRNV+R W YETGV GV++ + +P +EY+E+FGPDY ++V
Sbjct: 297 RSFNVPLLLLGGGGYTIRNVARCWCYETGVALGVEVEDKMPEHEYYEYFGPDYTLHVAPS 356
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDE 114
NM+N N R+ L+ I + NL + PSV + PP E DE
Sbjct: 357 NMENKNSRQMLEEIRNDLLHNLSKLQHAPSVPFQERPPDTETPEVDE 403
>gi|4193320 (AF045473) histone deacetylase [Zea mays]
Length = 458
Score = 273 bits (690), Expect = 1e-72
Identities = 120/217 (55%), Positives = 164/217 (75%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+Y+DIDVHHGDGVEEAF+T++RVM+V F + FPGTG + D G +GK+YA+NVPL
Sbjct: 182 RVLYVDIDVHHGDGVEEAFFTTNRVMTVSFHKYGDFFPGTGHITDVGAAEGKHYALNVPL 241
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
DGIDD ++ +F +++K + ++P+ +VLQCGADSL+GDRLGCFNLS KGHA+C++ +
Sbjct: 242 SDGIDDTTFRGLFQCIIKKVMEVYQPDVVVLQCGADSLAGDRLGCFNLSVKGHADCLRFL 301
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
SYN+PM+VLGGGGYTIRNV+R W YET V GV+ +PYN+Y+E+FGPDY +++
Sbjct: 302 RSYNVPMMVLGGGGYTIRNVARCWCYETAVAVGVEPDNKLPYNDYYEYFGPDYTLHIQPK 361
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
+++N N K L+NI + ENL + VPS Q D P
Sbjct: 362 SVENLNTTKDLENIKNMILENLSKIEHVPSTQFHDRP 398
>gi|4545130|gb|AAD22407|AF091326_1 (AF091326) histone deacetylase [Plasmodium falciparum]
Length = 449
Score = 271 bits (686), Expect = 4e-72
Identities = 128/240 (53%), Positives = 176/240 (73%), Gaps = 6/240 (2%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVP 618
+RVMYIDIDVHHGDGVEEAFY + RVM+V F + FPGTG + D G+ GK Y+VNVP
Sbjct: 166 ARVMYIDIDVHHGDGVEEAFYVTHRVMTVSFHKFGDYFPGTGDITDVGVNHGKYYSVNVP 225
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L DG+ D+++ +F V++K ++T++P I++QCGADSL+GDRLG FNL+ KGHA CV+
Sbjct: 226 LNDGMTDDAFVDLFKVVIDKCVQTYRPGAIIIQCGADSLTGDRLGRFNLTIKGHARCVEH 285
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGV--KLPEDIPYNEYFEHFGPDYKINV 264
V SYNIP+LVLGGGGYTIRNVSR WAYETGV+ ++P+ I N+Y++++ PD+++++
Sbjct: 286 VRSYNIPLLVLGGGGYTIRNVSRCWAYETGVVLNKHHEMPDQISLNDYYDYYAPDFQLHL 345
Query: 263 LSGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAF----IDCESDEKLLWSK 96
N+ NYN ++L I + ENLR + P VQ + +PP F ID ESD+ +
Sbjct: 346 QPSNIPNYNSPEHLSRIKMKIAENLRHIEHAPGVQFSYVPPDFFNSDIDDESDKNQY--E 403
Query: 95 FKEDKG 78
K+D G
Sbjct: 404 LKDDSG 409
>gi|3023947|sp|P56521|HDAC_MAIZE PROBABLE HISTONE DEACETYLASE (RPD3 HOMOLOG) >gi|2665840 (AF035815)
putative histone deacetylase RPD3 [Zea mays]
Length = 513
Score = 269 bits (680), Expect = 2e-71
Identities = 127/227 (55%), Positives = 162/227 (70%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+Y+DID+HHGDGVEEAFYT+DRVM+V F + FPGTG + D G KGK Y++NVPL
Sbjct: 182 RVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKFGDYFPGTGDIRDIGHSKGKYYSLNVPL 241
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
DGIDDESY+ +F ++ K + F+P +VLQCGADSLSGDRLGCFNLS KGHA CV+ +
Sbjct: 242 DDGIDDESYQSLFKPIMGKVMEVFRPGAVVLQCGADSLSGDRLGCFNLSIKGHAECVRYM 301
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
S+N+P+L+LGGGGYTIRNV+R W YETGV G + + +P NEY+E+FGPDY ++V
Sbjct: 302 RSFNVPLLLLGGGGYTIRNVARCWCYETGVALGQEPEDKMPVNEYYEYFGPDYTLHVAPS 361
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDE 114
NM+N N R+ LD+I L + PSV + P E DE
Sbjct: 362 NMENKNTRQQLDDI----RSKLSKLRHAPSVHFQERVPDTEIPEQDE 404
>gi|3023932|sp|P56520|HDA3_CHICK HISTONE DEACETYLASE 3 (HD3) >gi|2791688 (AF039753) histone
deacetylase-3; HD-3 [Gallus gallus]
Length = 428
Score = 264 bits (668), Expect = 5e-70
Identities = 121/217 (55%), Positives = 165/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ YA+NVP
Sbjct: 163 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYALNVP 222
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 223 LRDGIDDQSYKHLFQPVINQVVDYYQPTCIVLQCGADSLGRDRLGCFNLSIRGHGECVEY 282
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 283 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVDEAISEELPYSEYFEYFAPDFTLHPDV 342
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I +T+ ENL+ + PSVQI D+P
Sbjct: 343 STRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVP 381
>gi|4504363|oth|NP_003874|PHDAC3 UNKNOWN >gi|2326173 (U66914) histone deacetylase 3 [Homo sapiens]
Length = 428
Score = 264 bits (667), Expect = 6e-70
Identities = 120/217 (55%), Positives = 165/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 163 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 222
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 223 LRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 282
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 283 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 342
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I++T+ ENL+ + PSVQI D+P
Sbjct: 343 STRIENQNSRQYLDQILQTIFENLKMLNHAPSVQIHDVP 381
>gi|3023926|sp|O17695|HDA1_CAEEL PROBABLE HISTONE DEACETYLASE C53A5.3 >gi|3875199|emb|CAB03984|
(Z81486) predicted using Genefinder; Similarity to Yeast
RPD3 transcriptional regulatiry protein (SW:P32561);
cDNA EST EMBL:T02368 comes from this gene; cDNA EST
EMBL:D70319 comes from this gene; cDNA EST EMBL:D71057
comes from...
Length = 461
Score = 263 bits (665), Expect = 1e-69
Identities = 122/238 (51%), Positives = 163/238 (68%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+Y+DIDVHHGDGVEEAFYT+DRVM+V F + FPGTG L D G KGK Y+VNVPL
Sbjct: 173 RVLYVDIDVHHGDGVEEAFYTTDRVMTVSFHKYGDFFPGTGDLKDIGAGKGKLYSVNVPL 232
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DGI D SY+ IF ++ K + F P +VLQCGADSL+GDRLG FNL+ KGH C +
Sbjct: 233 RDGITDVSYQSIFKPIMTKVMERFDPCAVVLQCGADSLNGDRLGPFNLTLKGHGECARFF 292
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLSG 255
SYN+P++++GGGGYT RNV+R W YET + ++P ++PYN+YFE+FGP+Y++++ S
Sbjct: 293 RSYNVPLMMVGGGGYTPRNVARCWTYETSIAVDKEVPNELPYNDYFEYFGPNYRLHIESS 352
Query: 254 NMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCESDEKLLWSKFKEDK 81
N N N L + V NL + VPSVQ+ IP + +D+ L+ + DK
Sbjct: 353 NAANENSSDMLAKLQTDVIANLEQLTFVPSVQMRPIPEDALSALNDDSLIADQANPDK 410
>gi|2661170 (U75696) RPD3-2A [Homo sapiens]
Length = 429
Score = 262 bits (662), Expect = 2e-69
Identities = 120/217 (55%), Positives = 164/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 164 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 223
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 224 LRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 283
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 284 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 343
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I +T+ ENL+ + PSVQI D+P
Sbjct: 344 STRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVP 382
>gi|3639054 (AF074881) histone deacetylase 3 [Mus musculus] >gi|3676558
(AF079310) histone deacetylase 3 [Mus musculus]
Length = 424
Score = 262 bits (662), Expect = 2e-69
Identities = 120/217 (55%), Positives = 164/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 163 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 222
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 223 LRDGIDDQSYKHLFQPVISQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 282
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 283 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 342
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I +T+ ENL+ + PSVQI D+P
Sbjct: 343 STRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVP 381
>gi|3334210|sp|O15379|HDA3_HUMAN HISTONE DEACETYLASE 3 (HD3) >gi|2661172 (U75697) RPD3-2B [Homo
sapiens] >gi|2789656 (AF039703) histone deacetylase 3
[Homo sapiens] >gi|3201676|gb|AAC26509| (AF059650)
histone deacetylase 3 [Homo sapiens]
Length = 428
Score = 262 bits (662), Expect = 2e-69
Identities = 120/217 (55%), Positives = 164/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 163 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 222
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 223 LRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 282
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 283 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 342
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I +T+ ENL+ + PSVQI D+P
Sbjct: 343 STRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVP 381
>gi|2654535 (AF005482) histone deacetylase-3C [Homo sapiens]
Length = 371
Score = 262 bits (662), Expect = 2e-69
Identities = 120/217 (55%), Positives = 164/217 (75%), Gaps = 2/217 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 106 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 165
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 166 LRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 225
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 226 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 285
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIP 144
S ++N N R+YLD I +T+ ENL+ + PSVQI D+P
Sbjct: 286 STRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVP 324
>gi|3878853|emb|CAB03224| (Z81106) similar to Histone deacetylase family; cDNA EST
EMBL:M89215 comes from this gene [Caenorhabditis
elegans] >gi|3879019|emb|CAB03240| (Z81108) similar to
Histone deacetylase family; cDNA EST EMBL:M89215 comes
from this gene [Caenorhabditis elegans]
Length = 465
Score = 257 bits (649), Expect = 8e-68
Identities = 123/237 (51%), Positives = 170/237 (70%), Gaps = 6/237 (2%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDIDVHHGDGVEEAFYT+DRVM+V F FPGTG L D G GK YA+NVPL
Sbjct: 168 RVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKHGEYFPGTGDLKDVGAGSGKYYALNVPL 227
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
+DG+DD +YE IF ++ + + F+P +VLQCGADSL+GDRLG FNL+T GH CV+ +
Sbjct: 228 RDGVDDVTYERIFRTIMGEVMARFQPEAVVLQCGADSLAGDRLGVFNLTTYGHGKCVEYM 287
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINVLS- 258
S+N+P+L++GGGGYTIRNVSR W YET + ++ +D+P ++YF++F PDYK+++
Sbjct: 288 KSFNVPLLLVGGGGYTIRNVSRCWLYETAIALNQEVSDDLPLHDYFDYFIPDYKLHIKPL 347
Query: 257 GNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCES-----DEKLLWSKF 93
+ N+N +++D I + ENL+ + VPSVQ+ I + C+S DEKL+
Sbjct: 348 AALSNFNTPEFIDQTIVALLENLKQLPHVPSVQMQSISTS---CDSIVKTFDEKLIRDHQ 404
Query: 92 KED 84
+D
Sbjct: 405 NDD 407
>gi|3982757 (AF071559) histone deacetylase dHDAC3 [Drosophila melanogaster]
Length = 438
Score = 243 bits (615), Expect = 8e-64
Identities = 122/242 (50%), Positives = 166/242 (68%), Gaps = 11/242 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDIDVHHGDGV+EAFY +DRVM+ F N FPGTG + + G G+ Y+VNVP
Sbjct: 168 RVLYIDIDVHHGDGVQEAFYLTDRVMTASFHKYGNYFFPGTGDMYEIGAESGRYYSVNVP 227
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
LK+GIDD+SY +F ++ + ++P IVLQCGADSL+GDRLGCF+LSTKGH CVK
Sbjct: 228 LKEGIDDQSYFQVFKPIISAIMDFYRPTAIVLQCGADSLAGDRLGCFSLSTKGHGECVKF 287
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKIN-VL 261
V N+P LV+GGGGYT+RNV+R W +ET ++ + D+P EY++ F PD+ ++ +
Sbjct: 288 VKELNVPTLVVGGGGYTLRNVARCWTHETSLLVDQDIENDLPATEYYDFFAPDFTLHPEI 347
Query: 260 SGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDCE---------SDEKL 108
+ N N ++YL+ I+K V ENL+ PSVQ+ PP +D E SD +
Sbjct: 348 NSRQDNANSKQYLELIVKHVYENLKMCQHSPSVQMVQTPPD-VDLEELRSNREEASDPDV 406
Query: 107 LWSKFKEDKGIDS 69
S EDK +D+
Sbjct: 407 RISVADEDKLVDA 419
>gi|1723948|sp|P53096|HOS2_YEAST PROBABLE HISTONE DEACETYLASE HOS2 >gi|2133059|pir||S64211 probable
transcription regulator YGL194c - yeast (Saccharomyces
cerevisiae) >gi|1322819|emb|CAA96906| (Z72716) ORF
YGL194c [Saccharomyces cerevisiae]
Length = 452
Score = 238 bits (602), Expect = 3e-62
Identities = 130/242 (53%), Positives = 169/242 (69%), Gaps = 8/242 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
R++YIDID+HHGDGV+EAFYT+DRV +S H N E FPGTG L + G KGK++A+NV
Sbjct: 187 RILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKYNGE-FFPGTGDLTEIGCDKGKHFALNV 245
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVK 441
PL+DGIDD+SY +F +V+ I TFKP IV QCGADSL DRLGCFNL+ K H CVK
Sbjct: 246 PLEDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGECVK 305
Query: 440 TVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYF-EHFGPDYKI-N 267
V S+ +PMLV+GGGGYT RNVSR W YETG++ V LPEDIP + F + FGPDY +
Sbjct: 306 FVKSFGLPMLVVGGGGYTPRNVSRLWTYETGILNDVLLPEDIPEDIPFRDSFGPDYSLYP 365
Query: 266 VLSGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITD--IPPAFIDC--ESDEKLLWS 99
+L +N N +K L++I EN+R + PSV++ IP I E ++K++
Sbjct: 366 MLDDLYENKNSKKLLEDIRIRCLENIRYLQGAPSVRMDAECIPTQDISALTEEEDKII-Q 424
Query: 98 KFKEDKGIDS 69
+ E+ DS
Sbjct: 425 EMNEETEADS 434
>gi|2995806 (AF053139) histone deacetylase 3 [Homo sapiens]
Length = 259
Score = 233 bits (589), Expect = 9e-61
Identities = 105/189 (55%), Positives = 144/189 (75%), Gaps = 2/189 (1%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN-IFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV+EAFY +DRVM+V F N FPGTG + + G G+ Y +NVP
Sbjct: 69 RVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVP 128
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGIDD+SY+++F V+ + + ++P IVLQCGADSL DRLGCFNLS +GH CV+
Sbjct: 129 LRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEY 188
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEHFGPDYKINV-L 261
V S+NIP+LVLGGGGYT+RNV+R W YET ++ + E++PY+EYFE+F PD+ ++ +
Sbjct: 189 VKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDV 248
Query: 260 SGNMKNYNDRK 228
S ++N N R+
Sbjct: 249 STRIENQNSRQ 259
>gi|3024397|sp|O13298|PHD1_SCHPO PROBABLE HISTONE DEACETYLASE PHD1 >gi|2641699|dbj|BAA23598|
(AB008888) Phd1p [Schizosaccharomyces pombe]
>gi|2706458|emb|CAA15916.1| (AL021046) histone
deacetylase [Schizosaccharomyces pombe]
Length = 434
Score = 230 bits (581), Expect = 8e-60
Identities = 115/229 (50%), Positives = 155/229 (67%), Gaps = 5/229 (2%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINME-NIFPGTGALNDTGILKGKNYAVNVP 618
RV+YIDID+HHGDGV++AFY SDRV++V F + FP TG ++ G+ GK +A+NVP
Sbjct: 186 RVLYIDIDIHHGDGVQQAFYESDRVLTVSFHKYNGDFFPATGNFDENGVKGGKYFALNVP 245
Query: 617 LKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKT 438
L+DGI DE Y +F ++E I TF+P+ IVLQCGADSL DRLG FNLS H CV+
Sbjct: 246 LEDGIGDEQYTSLFKSIIEPTINTFQPSAIVLQCGADSLGYDRLGVFNLSIHAHGECVRF 305
Query: 437 VMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNE-YFEHFGPDYKINV- 264
S+NIPMLV+GGGGYT+RNV+R W YET + ++P ++P Y+E F PDY ++
Sbjct: 306 TRSFNIPMLVVGGGGYTLRNVARAWCYETSICVNEQIPSELPRETLYYEFFAPDYTLHPR 365
Query: 263 LSGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFIDC--ESDEKL 108
L+ ++N N K L+++ E LR + PSVQ+ IPP E DE+L
Sbjct: 366 LTTKIENKNTPKALEDLRIRALEQLRYLGGAPSVQMQQIPPDLTGHLEEEDERL 419
>gi|1177634|emb|CAA62950| (X91837) putative transcriptional regulator [Saccharomyces
cerevisiae]
Length = 452
Score = 227 bits (573), Expect = 7e-59
Identities = 127/242 (52%), Positives = 166/242 (68%), Gaps = 8/242 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
R++YIDID+HHGDGV+EAFYT+DRV +S H N E FPGTG L + G KGK++A+NV
Sbjct: 187 RILYIDIDLHHGDGVQEAFYTTDRVFTLSFHKYNGE-FFPGTGDLTEIGCDKGKHFALNV 245
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVK 441
PL+DGIDD+SY +F +V+ I TFKP IV QCGADSL DRLGCFNL+ K H CVK
Sbjct: 246 PLEDGIDDDSYINLFKSIVDPLIMTFKPTLIVQQCGADSLGHDRLGCFNLNIKAHGECVK 305
Query: 440 TVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYF-EHFGP-DYKIN 267
V S+ +PMLV+GGGGYT RNVSR W YETG++ V LPEDIP + + H G + I
Sbjct: 306 FVKSFGLPMLVVGGGGYTPRNVSRLWTYETGILNDVLLPEDIPEDIHSGTHSGRIIHFIP 365
Query: 266 VLSGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITD--IPPAFIDC--ESDEKLLWS 99
+L +N N +K L++I EN+R + PSV++ IP I E ++K++
Sbjct: 366 MLDDLYENKNSKKLLEDIRIRCLENIRYLQGAPSVRMDAECIPTQDISALTEEEDKII-Q 424
Query: 98 KFKEDKGIDS 69
+ E+ DS
Sbjct: 425 EMNEETEADS 434
>gi|1176665|sp|Q09440|HDA2_CAEEL PUTATIVE HISTONE DEACETYLASE C08B11.2 >gi|3874170|emb|CAA86662|
(Z46676) similar to transcriptional regulatory protein
(RPD3) [Caenorhabditis elegans]
Length = 507
Score = 201 bits (506), Expect = 5e-51
Identities = 110/229 (48%), Positives = 141/229 (61%), Gaps = 5/229 (2%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV+YIDID+HHGDGV+EAF SDRVM+V F FPG+G++ D G+ GK +A+NVPL
Sbjct: 190 RVLYIDIDIHHGDGVQEAFNNSDRVMTVSFHRFGQYFPGSGSIMDKGVGPGKYFAINVPL 249
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
I DE Y +F V+ F P IVLQCG+DSL DRLG F LS HA VK V
Sbjct: 250 MAAIRDEPYLKLFESVISGVEENFNPEAIVLQCGSDSLCEDRLGQFALSFNAHARAVKYV 309
Query: 434 MSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIPYNEYFEH-FGPDYKINVLS 258
S P++VLGGGGYT+RNV+R WA ETGVI G+++ ++IP + H F P L
Sbjct: 310 KSLGKPLMVLGGGGYTLRNVARCWALETGVILGLRMDDEIPGTSLYSHYFTPRLLRPNLV 369
Query: 257 GNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQITDIPPAFID----CESDEKL 108
M + N YL +I K LR + PSVQ+ +I +D E +E+L
Sbjct: 370 PKMNDANSAAYLASIEKETLACLRMIRGAPSVQMQNIVGIRLDEIEQIEENERL 423
>gi|3639056 (AF074882) histone deacetylase 3 [Mus musculus]
Length = 233
Score = 147 bits (368), Expect = 7e-35
Identities = 67/122 (54%), Positives = 92/122 (74%), Gaps = 1/122 (0%)
Query: 509 DSLSGDRLGCFNLSTKGHANCVKTVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVK 330
DSL DRLGCFNLS +GH CV+ V S+NIP+LVLGGGGYT+RNV+R W YET ++
Sbjct: 68 DSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEA 127
Query: 329 LPEDIPYNEYFEHFGPDYKINV-LSGNMKNYNDRKYLDNIIKTVTENLRDVIPVPSVQIT 153
+ E++PY+EYFE+F PD+ ++ +S ++N N R+YLD I +T+ ENL+ + PSVQI
Sbjct: 128 ISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIH 187
Query: 152 DIP 144
D+P
Sbjct: 188 DVP 190
>gi|2833221|sp|Q12214|HOS1_YEAST HOS1 PROTEIN >gi|1084790|pir||S54089 hypothetical protein YPR068c -
yeast (Saccharomyces cerevisiae)
>gi|805048|emb|CAA89185| (Z49219) unknown [Saccharomyces
cerevisiae] >gi|1314136|emb|CAA94976| (Z71255) unknown
[Saccharomyces cerevisiae]
Length = 470
Score = 108 bits (267), Expect = 5e-23
Identities = 61/149 (40%), Positives = 92/149 (60%), Gaps = 4/149 (2%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
+++ Y+D D+HHGDGVE+AF S ++ +SVH FPGTG+L+D+ K KN VN
Sbjct: 239 NKITYVDFDLHHGDGVEKAFQYSKQIQTISVHLYE-PGFFPGTGSLSDSR--KDKN-VVN 294
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCV 444
+PLK G DD E I +++V I +P ++++CG D L GDR + L+ +G + +
Sbjct: 295 IPLKHGCDDNYLELIASKIVNPLIERHEPEALIIECGGDGLLGDRFNEWQLTIRGLSRII 354
Query: 443 KTVM-SY-NIPMLVLGGGGYTIRNVSRTWAYET 351
+M SY + +LGGGGY +SR + Y T
Sbjct: 355 INIMKSYPRAHIFLLGGGGYNDLLMSRFYTYLT 387
>gi|2983524 (AE000719) acetoin utilization protein [Aquifex aeolicus]
Length = 375
Score = 99.8 bits (245), Expect = 2e-20
Identities = 65/196 (33%), Positives = 100/196 (50%), Gaps = 14/196 (7%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFP-GTGALNDTGILKGKNYAVN 624
R++YID+D HH DGV+EAFY +D+V +S+H + E FP G L + G KGK Y +N
Sbjct: 161 RILYIDLDAHHCDGVQEAFYDTDQVFVLSLHQ-SPEYAFPFEKGFLEEIGEGKGKGYNLN 219
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCV 444
+PL G++D + + + +E F+P +LQ G D L D L FNLS
Sbjct: 220 IPLPKGLNDNEFLFALEKSLEIVKEVFEPEVYLLQLGTDPLLEDYLSKFNLSNVAFLKAF 279
Query: 443 KTVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPE-----------DIPYNEYF 297
V + LGGGGY ++R W + G ++PE I + E+
Sbjct: 280 NIVREVFGEGVYLGGGGYHPYALARAWTLIWCELSGREVPEKLNNKAKELLKSIDFEEFD 339
Query: 296 EHFGPDYKINVLSGNMKNYNDRKYLDNIIK 207
+ Y + L + RK + + ++
Sbjct: 340 DEVDRSYMLETLKDPWRGGEVRKEVKDTLE 369
>gi|3024859|sp|O30107|Y130_ARCFU HYPOTHETICAL PROTEIN AF0130 >gi|2650515 (AE001097) acetylpolyamine
aminohydrolase (aphA) [Archaeoglobus fulgidus]
Length = 359
Score = 93.2 bits (228), Expect = 2e-18
Identities = 42/122 (34%), Positives = 68/122 (55%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
R+ +D D HHGDG +E FY DRV+ + M ++PGTG + G KG+ Y VN+PL
Sbjct: 155 RIAILDWDAHHGDGTQEIFYNDDRVLFISTHQMP-LYPGTGYPEECGTGKGEGYTVNIPL 213
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
G DE Y + ++++E + FKP I + G D+ D + L+ +G+A ++
Sbjct: 214 PPGTGDEGYMMVIDEIIEPVVNEFKPQFIAISAGQDNHFTDPITSLALTARGYAEMMRRA 273
Query: 434 MS 429
++
Sbjct: 274 VA 275
>gi|3023253|sp|Q56195|ACUC_STAXY ACETOIN UTILIZATION ACUC PROTEIN >gi|1177686|emb|CAA64714| (X95439)
acuC [Staphylococcus xylosus]
Length = 385
Score = 91.7 bits (224), Expect = 6e-18
Identities = 58/157 (36%), Positives = 87/157 (54%), Gaps = 17/157 (10%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
RV+ ID D HHGDG + +FYT+D+ + S+H + +FPG+G + G KG Y VN+
Sbjct: 166 RVLCIDTDAHHGDGTQWSFYTNDQALIYSIHETG-KFLFPGSGHYTERGAEKGFGYTVNI 224
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVK 441
PL+ +D+S+ +F Q +E + +FKP+ IV G D L H +C
Sbjct: 225 PLEPYTEDQSFLDVFKQTIEPVVASFKPDIIVSVHGVD--------VHYLDPLTHMSCTL 276
Query: 440 TVMSYNIPMLV--------------LGGGGYTI-RNVSRTWAYETGVICGVKLP 324
+ Y IP +V GGGGY I + V R W++ + G + P
Sbjct: 277 NTL-YEIPYIVKSLADTYTQGKVIMFGGGGYNIWKVVPRAWSHVFLALIGEQPP 329
>gi|1730711|sp|P53973|HDA1_YEAST HISTONE DEACETYLASE HDA1 >gi|2131864|pir||S62933 hypothetical
protein YNL021w - yeast (Saccharomyces cerevisiae)
>gi|1301851|emb|CAA95883| (Z71297) ORF YNL021w
[Saccharomyces cerevisiae]
Length = 706
Score = 85.8 bits (209), Expect = 3e-16
Identities = 54/161 (33%), Positives = 94/161 (57%), Gaps = 8/161 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGT--GALNDTGILKGKNYAV 627
R+M +D D+HHG+G +++FY D+V+ S+H M +PGT G + TG KG+ +
Sbjct: 238 RIMILDWDIHHGNGTQKSFYQDDQVLYVSLHRFEMGKYYPGTIQGQYDQTGEGKGEGFNC 297
Query: 626 NVPLK-DGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNL--STKGH 456
N+ G+ D Y + F QVV R FKP+ +++ G D+ GD +G ++ S GH
Sbjct: 298 NITWPVGGVGDAEYMWAFEQVVMPMGREFKPDLVIISSGFDAADGDTIGQCHVTPSCYGH 357
Query: 455 -ANCVKTVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPEDIP 312
+ +K++ N + V+ GGY + ++R+ V+ G + P+++P
Sbjct: 358 MTHMLKSLARGN--LCVVLEGGYNLDAIARSALSVAKVLIG-EPPDELP 403
>gi|3024905|sp|Q57955|Y535_METJA HYPOTHETICAL PROTEIN MJ0535 >gi|2127738|pir||G64366 acetylpolyamine
aminohydolase - Methanococcus jannaschii >gi|1591238
(U67502) acetylpolyamine aminohydrolase (aphA)
[Methanococcus jannaschii]
Length = 343
Score = 85.0 bits (207), Expect = 6e-16
Identities = 41/136 (30%), Positives = 73/136 (53%)
Query: 806 NITSRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAV 627
N +V+ ID DVHHG+G +E F+ +RV+ + F + I+PGTG + D G + K +
Sbjct: 154 NYMKKVIIIDFDVHHGNGTQEIFWNDNRVIHIDF-HQRGIYPGTGDILDIGGEEAKGTKI 212
Query: 626 NVPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANC 447
N+P D Y + +N++VE + F P+T+++ G D+ D L +L+ +
Sbjct: 213 NLPFPAHSTDADYIFAWNEIVEPILNYFSPDTVLVSAGFDAFINDGLASMDLTETFYRFV 272
Query: 446 VKTVMSYNIPMLVLGG 399
+ Y++ ++ GG
Sbjct: 273 GAKLSGYSVTAVLEGG 288
>gi|2984320 (AE000773) acetoin utilization protein [Aquifex aeolicus]
Length = 310
Score = 84.7 bits (206), Expect = 7e-16
Identities = 47/139 (33%), Positives = 76/139 (53%), Gaps = 5/139 (3%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIF-PGTGALNDTGILKGKNYAVNV 621
++V ID D HHG+G +++FY D V +F E F PGTG+ ++ G KG Y NV
Sbjct: 154 NKVFIIDFDAHHGNGTQKSFYEDDTVF--YFSTHEYPFYPGTGSEDERGAGKGYGYTYNV 211
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKG----HA 453
P+ G D+ Y ++ +++ + + F P+ +++ G D D L N+S +G
Sbjct: 212 PMSAGAGDDEYIPVYEKLLPELMNRFSPDFVLVSAGYDLHRDDPLTYLNVSNEGVRQIVR 271
Query: 452 NCVKTVMSYNIPMLVLGGGGYTIR 381
N +KT N P+L GGY ++
Sbjct: 272 NIIKTSDELNAPVLFALEGGYNLK 295
>gi|728801|sp|P39067|ACUC_BACSU ACETOIN UTILIZATION ACUC PROTEIN >gi|628994|pir||S39643 acetate
utilization protein acuC - Bacillus subtilis >gi|348050
(L17309) acetoin utilization protein [Bacillus subtilis]
>gi|2293316 (AF008220) acetoin catabolism protein AcuC
[Bacillus subtilis] >gi|2635455|emb|CAB14949| (Z99119)
acetoin dehydrogenase [Bacillus subtilis]
Length = 387
Score = 82.7 bits (201), Expect = 3e-15
Identities = 57/163 (34%), Positives = 85/163 (51%), Gaps = 15/163 (9%)
Query: 800 TSRVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAV 627
++RV+YID D HHGDGV+ FY + V +S+H +FPGTG + + G KG Y+
Sbjct: 160 SARVLYIDTDAHHGDGVQFTFYDNPDVCTLSIHETG-RYLFPGTGQIQEKGSGKGYGYSF 218
Query: 626 NVPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLS------- 468
N+PL +D+S+ + + F+P+ I+ Q GAD+ D L + +
Sbjct: 219 NIPLDAFTEDDSFLEAYRTAASEVAAYFEPDVIISQNGADAHYYDPLTHLSATINIYEEI 278
Query: 467 -----TKGHANCVKTVMSYNIPMLVLGGGGYTI-RNVSRTWAYETGVICGVKLPEDIP 312
T H C + +GGGGY I R V R WA + G+ +IP
Sbjct: 279 PRLAHTLAHQYC-------GGKWIAVGGGGYDIWRVVPRAWARIWLEMKGIDPGHEIP 329
>gi|3257687|dbj|BAA30370| (AP000005) 335aa long hypothetical protein [Pyrococcus horikoshii]
Length = 335
Score = 82.7 bits (201), Expect = 3e-15
Identities = 41/138 (29%), Positives = 72/138 (51%)
Query: 800 TSRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
T + ID D HHG+G +E F+ V+ V ++ +I+PG+G +N+ G + +N+
Sbjct: 154 TGEALIIDFDAHHGNGTQEIFWNDPEVVHVD-LHERDIYPGSGDVNEIGGYNARGSKINI 212
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVK 441
P+ DD Y Y +N++V + KP I++ G D GD L L+ ++
Sbjct: 213 PMPHYSDDGDYIYAWNEIVLPIVERVKPKVIIVSAGFDGFKGDGLTTLKLTEIFYSYAGV 272
Query: 440 TVMSYNIPMLVLGGGGYT 387
T+ Y P++++ GGY+
Sbjct: 273 TLRKY--PLVLILEGGYS 288
>gi|3023933|sp|P56523|HDA1_SCHPO HYPOTHETICAL 76.8 KD PROTEIN IN CHROMOSOME II >gi|4159999
(AF064207) putative histone deacetylase
[Schizosaccharomyces pombe]
Length = 687
Score = 80.4 bits (195), Expect = 1e-14
Identities = 47/141 (33%), Positives = 76/141 (53%), Gaps = 6/141 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMEN--IFPGT--GALNDTGILKGKNYAV 627
RV+ +D D+HHG+G + AFY V+ V EN +PGT G + G G V
Sbjct: 227 RVLIVDWDIHHGNGTQMAFYDDPNVLYVSLHRYENGRFYPGTNYGCAENCGEGPGLGRTV 286
Query: 626 NVPLK-DGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
N+P G+ D Y Y F +VV F P+ +++ CG D+ +GD +G F L+ +A+
Sbjct: 287 NIPWSCAGMGDGDYIYAFQRVVMPVAYEFDPDLVIVSCGFDAAAGDHIGQFLLTPAAYAH 346
Query: 449 CVKTVMSY-NIPMLVLGGGGYTIRNVS 372
+ +M + + + GGY + ++S
Sbjct: 347 MTQMLMGLADGKVFISLEGGYNLDSIS 373
>gi|3024889|sp|P56524|Y288_HUMAN HYPOTHETICAL PROTEIN KIAA0288 (HA6116) >gi|2564324|dbj|BAA22957|
(AB006626) KIAA0288 [Homo sapiens]
Length = 967
Score = 76.5 bits (185), Expect = 2e-13
Identities = 48/138 (34%), Positives = 76/138 (54%), Gaps = 9/138 (6%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
S+++ +D DVHHG+G ++AFY+ V MS+H + N FPG+GA ++ G G + VN
Sbjct: 715 SKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVN 774
Query: 623 VPLKDGID----DESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG--DRLGCFNLSTK 462
+ G+D D Y F VV F P+ +++ G D++ G LG +NLS +
Sbjct: 775 MAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSAR 834
Query: 461 GHANCVKTVMSYNIPMLVLG-GGGYTI 384
K +M +VL GG+ +
Sbjct: 835 CFGYLTKQLMGLAGGRIVLALEGGHDL 861
>gi|2435529 (AF026202) contains similarity to S. cerevisiae transcriptional
regulatory protein RPD3 (SP:P32561) [Caenorhabditis
elegans]
Length = 796
Score = 76.5 bits (185), Expect = 2e-13
Identities = 46/142 (32%), Positives = 80/142 (55%), Gaps = 6/142 (4%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
+++ ID DVHHG+G + +F V MS+H + N FPGTG++ + G K VN
Sbjct: 569 AKIAIIDWDVHHGNGTQLSFENDPNVLYMSLHRHDKGNFFPGTGSVTEVGKNDAKGLTVN 628
Query: 623 VPLK-DGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG--DRLGCFNLSTKGHA 453
VP D + D Y + V+E + +F P+ I++ G D+ G + LG + ++ +
Sbjct: 629 VPFSGDVMRDPEYLAAWRTVIEPVMASFCPDFIIVSAGFDACHGHPNALGGYEVTPEMFG 688
Query: 452 NCVKTVMSYNIPMLVLG-GGGYTIRNVS 372
K++++Y +VL GGY ++++S
Sbjct: 689 YMTKSLLNYASGKVVLALEGGYDLKSIS 716
>gi|4490314|emb|CAB38805| (AL035678) putative protein [Arabidopsis thaliana]
Length = 359
Score = 74.9 bits (181), Expect = 6e-13
Identities = 45/145 (31%), Positives = 76/145 (52%), Gaps = 7/145 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
R+ ID DVHHG+G +AF T D + + + +PGTG ++D G KG+ +N+PL
Sbjct: 168 RIFIIDFDVHHGNGTNDAF-TEDPDIFFLSTHQDGSYPGTGKISDIGKGKGEGTTLNLPL 226
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
G D + +F +++ + FKP+ I++ G D+ D L +T + + K +
Sbjct: 227 PGGSGDIAMRTVFEEIIVPCAQRFKPDIILVSAGYDAHVLDPLANLQFTTATYYSLAKDI 286
Query: 434 MSYNIPMLVLGG-------GGYTIRNVSRTWA 360
+ V GG GGY + ++S + A
Sbjct: 287 K--RLAKEVCGGRCVFFLEGGYNLESLSSSVA 316
>gi|4101722 (AF006602) histone deacetylase mHDA1 [Mus musculus]
Length = 991
Score = 72.6 bits (175), Expect = 3e-12
Identities = 45/133 (33%), Positives = 73/133 (54%), Gaps = 10/133 (7%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
+V+ +D D+HHG+G ++AFY V+ S+H + N FPG+GA + G G Y VNV
Sbjct: 732 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV 791
Query: 620 PLKDGID----DESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG--DRLGCFNLSTK- 462
G+D D Y F VV + F P+ +++ G D++ G LG ++++ +
Sbjct: 792 AWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC 851
Query: 461 -GHANCVKTVMSYNIPMLVLGGG 396
GH ++ +L L GG
Sbjct: 852 FGHLTRQLMTLAGGRVVLALEGG 874
>gi|3043724|dbj|BAA25526| (AB011172) KIAA0600 protein [Homo sapiens]
Length = 716
Score = 72.2 bits (174), Expect = 4e-12
Identities = 45/133 (33%), Positives = 72/133 (53%), Gaps = 10/133 (7%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
+V+ +D D+HHG+G ++AFY V+ S+H + N FPG+GA + G G Y VNV
Sbjct: 457 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV 516
Query: 620 PLKDGID----DESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG--DRLGCFNLSTK- 462
G+D D Y F VV F P+ +++ G D++ G LG ++++ +
Sbjct: 517 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC 576
Query: 461 -GHANCVKTVMSYNIPMLVLGGG 396
GH ++ +L L GG
Sbjct: 577 FGHLTRQLMTLAGGRVVLALEGG 599
>gi|3170182 (AF039691) antigen NY-CO-9 [Homo sapiens]
Length = 897
Score = 72.2 bits (174), Expect = 4e-12
Identities = 45/133 (33%), Positives = 72/133 (53%), Gaps = 10/133 (7%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
+V+ +D D+HHG+G ++AFY V+ S+H + N FPG+GA + G G Y VNV
Sbjct: 675 KVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNV 734
Query: 620 PLKDGID----DESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG--DRLGCFNLSTK- 462
G+D D Y F VV F P+ +++ G D++ G LG ++++ +
Sbjct: 735 AWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARC 794
Query: 461 -GHANCVKTVMSYNIPMLVLGGG 396
GH ++ +L L GG
Sbjct: 795 FGHLTRQLMTLAGGRVVLALEGG 817
>gi|3024979|sp|O27262|YB94_METTH HYPOTHETICAL PROTEIN MTH1194 >gi|2622302 (AE000887) acetylpolyamine
aminohydolase [Methanobacterium thermoautotrophicum]
Length = 331
Score = 70.6 bits (170), Expect = 1e-11
Identities = 35/104 (33%), Positives = 59/104 (56%), Gaps = 2/104 (1%)
Query: 797 SRVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVN 624
SR + +D DVHHG+G FY VM S+H + +FPGTG +++TG +G+ + +N
Sbjct: 147 SRPLVLDFDVHHGNGTSSIFYRDRDVMYISIHQ-DPRTLFPGTGFIDETGSGEGEGFNLN 205
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRL 486
+P+ G + Y +I ++ + F+P+ I + G D+ D L
Sbjct: 206 IPMPRGSGNREYLWILGMILPAVLEGFRPDMIFVSAGFDAHRRDPL 251
>gi|3881091|emb|CAA21669| (AL032644) similar to Histone deacetylase family; cDNA EST
EMBL:C11820 comes from this gene [Caenorhabditis
elegans]
Length = 498
Score = 67.9 bits (163), Expect = 8e-11
Identities = 39/157 (24%), Positives = 77/157 (48%), Gaps = 5/157 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSD----RVMSVHFINMENIFPGTGALNDTGILKGKNYAV 627
+V+ +D DVH G+G +E +++S+H + +P + TGI +
Sbjct: 147 KVLIVDYDVHAGNGTQECVEQMGEGNVQLISIHRYENGHFWPN---MPQTGIYHNYKNTI 203
Query: 626 NVPLKD-GIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
N+PL G+ D Y +F ++ I F+P+ +++ G D+ GD G ++ G A
Sbjct: 204 NLPLNTIGLTDADYHALFTHIILPTIHAFQPDLLLVSSGFDASIGDPEGSMQVTPAGFAT 263
Query: 449 CVKTVMSYNIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLP 324
++ ++ IP+ L GGY + ++ + + G ++P
Sbjct: 264 MIRMLIDTGIPVAALLEGGYFLDALAADSEWVLRALLGEEIP 305
>gi|3025216|sp|Q20296|YLFN_CAEEL HYPOTHETICAL 89.8 KD PROTEIN F41H10.6 IN CHROMOSOME IV >gi|1397334
(U61954) partial CDS, similar to bacillus subtilis
acetoin utilization ACUC protein (SP:P39067)
[Caenorhabditis elegans]
Length = 798
Score = 67.9 bits (163), Expect = 8e-11
Identities = 45/143 (31%), Positives = 75/143 (51%), Gaps = 11/143 (7%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFP--GTGALNDTGILKGKNYAV 627
RV+ +D DVHHG+G +E FY V MS+H + N +P +D G G+ +V
Sbjct: 591 RVLILDWDVHHGNGTQEIFYEDSNVMYMSIHRHDKGNFYPIGEPKDYSDVGEGAGEGMSV 650
Query: 626 NVPLKD-GIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NVP + D Y+ F +V+ F P+ +++ G D+ D LG + ++ + A
Sbjct: 651 NVPFSGVQMGDNEYQMAFQRVIMPIAYQFNPDLVLISAGFDAAVDDPLGEYKVTPETFA- 709
Query: 449 CVKTVMSYNIPMLVLG------GGGYTIRNVSRT 366
+M+Y + L G GGY + ++S +
Sbjct: 710 ----LMTYQLSSLAGGRIITVLEGGYNLTSISNS 739
Score = 62.5 bits (149), Expect = 4e-09
Identities = 44/135 (32%), Positives = 68/135 (49%), Gaps = 6/135 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
R++ +D+DVHHG G + FY RV+ S+H +P + G KG Y
Sbjct: 175 RILIVDLDVHHGHGTQRIFYDDKRVLYFSIHRHEHGLFWPHLPESDFDHIGSGKGLGYNA 234
Query: 626 NVPLKD-GIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
N+ L + G D Y I V+ F P+ +++ G D+L GD LG L+ G+++
Sbjct: 235 NLALNETGCTDSDYLSIIFHVLLPLATQFDPHFVIISAGFDALLGDPLGGMCLTPDGYSH 294
Query: 449 CVKTVMSY-NIPMLVLGGGGY 390
+ + S MLV+ GGY
Sbjct: 295 ILYHLKSLAQGRMLVVLEGGY 315
>gi|4455131|gb|AAD21090| (AF129433) histone deacetylase HDA2 [Drosophila melanogaster]
Length = 883
Score = 67.5 bits (162), Expect = 1e-10
Identities = 44/157 (28%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
RV+ +D DVHHG+G + F ++ +V+ S+H + FP G + G G+ + V
Sbjct: 619 RVLIVDWDVHHGNGTQHIFESNPKVLYISLHRYEHGSFFPKGPDGNFDVVGKGAGRGFNV 678
Query: 626 NVPL-KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
N+P K G+ D Y F Q++ F P +++ G D+ GD LG ++ +G+
Sbjct: 679 NIPWNKKGMGDLEYALAFQQLIMPIAYEFNPQLVLVSAGFDAAIGDPLGGCKVTAEGYGM 738
Query: 449 CVKTVMSY-NIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLP 324
+ + + ++V GGY + ++S T + G +P
Sbjct: 739 LTHWLSALASGRIIVCLEGGYNVNSISYAMTMCTKTLLGDPVP 781
Score = 54.3 bits (128), Expect = 1e-06
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 5/100 (5%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
R++ ID DVHHG G + FY RV+ S+H + +P + G G Y
Sbjct: 192 RILIIDYDVHHGQGTQRFFYNDPRVVYFSIHRFEHGSFWPHLHESDYHAIGSGAGTGYNF 251
Query: 626 NVPLK-DGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSG 495
NVPL G+ + Y IF Q++ F+P I++ G D+ G
Sbjct: 252 NVPLNATGMTNGDYLAIFQQLLLPVALEFQPELIIVSAGYDAALG 296
>gi|4165861 (AF006603) histone deacetylase mHDA2 [Mus musculus]
Length = 1095
Score = 64.4 bits (154), Expect = 9e-10
Identities = 44/158 (27%), Positives = 79/158 (49%), Gaps = 6/158 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
R++ +D DVHHG+G + F V+ S+H + FP GA + G G + V
Sbjct: 587 RILIVDWDVHHGNGTQHIFEDDPSVLYVSLHRYDRGTFFPMGDEGASSQVGRDAGIGFTV 646
Query: 626 NVPLKDG-IDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NVP + D Y ++++V F P +++ G D+ GD LG ++ +G+A+
Sbjct: 647 NVPWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLISAGFDAAQGDPLGGCQVTPEGYAH 706
Query: 449 CVKTVMSY-NIPMLVLGGGGYTIRNVSRTWAYETGVICGVKLPE 321
+M ++++ GGY + ++S + A T + G P+
Sbjct: 707 LTHLLMGLAGGRIILILEGGYNLASISESMAACTHSLLGDPPPQ 750
Score = 61.7 bits (147), Expect = 6e-09
Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 6/142 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALN--DTGILKGKNYAV 627
RV+ +D DVHHG G + F V+ S+H +P A N G +G+ Y +
Sbjct: 191 RVLIVDWDVHHGQGTQFIFDQDPSVLYFSIHRYEHGRFWPHLKASNWSTIGFGQGQGYTI 250
Query: 626 NVPL-KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NVP + G+ D Y F ++ F+P +++ G D+L GD G + G A+
Sbjct: 251 NVPWNQTGMRDADYIAAFLHILLPVASEFQPQLVLVAAGFDALHGDPKGEMAATPAGFAH 310
Query: 449 CVKTVMSYNIPMLVLG-GGGYTIRNVSR 369
+M L+L GGY +R +++
Sbjct: 311 LTHLLMGLAGGKLILSLEGGYNLRALAK 338
>gi|3024891|sp|P72702|Y245_SYNY3 HYPOTHETICAL 33.6 KD PROTEIN SLR0245 >gi|1651782|dbj|BAA16709|
(D90900) acetylpolyamine aminohydolase [Synechocystis
sp.]
Length = 304
Score = 64.4 bits (154), Expect = 9e-10
Identities = 44/143 (30%), Positives = 71/143 (48%), Gaps = 1/143 (0%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVNVPL 615
RV +D DVHHG+G E + R+ ++ +PGTGA D G + +N+PL
Sbjct: 156 RVAILDWDVHHGNGTEALVDHNPRIFYCS-LHQFPCYPGTGAAGDRG---QHDNVLNIPL 211
Query: 614 KDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTV 435
K G D + Y F V +R KP+ +++ G D+ D L NL + + +
Sbjct: 212 KPGGDGKVYREAFEHKVLPFLRQVKPDLLLVSAGYDANHSDPLAYMNLIPEDYGMMTHYL 271
Query: 434 MSYNIPMLVLG-GGGYTIRNVSRT 366
M + P VLG GGY + +++++
Sbjct: 272 MEIS-PYPVLGLEGGYHLPSLAKS 294
>gi|3776071|emb|CAA09893| (AJ011972) histone deacetylase-like protein [Homo sapiens]
Length = 1215
Score = 64.4 bits (154), Expect = 9e-10
Identities = 45/138 (32%), Positives = 65/138 (46%), Gaps = 6/138 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALN--DTGILKGKNYAV 627
RV+ +D DVHHG G + F V+ S+H +P A N TG +G+ Y +
Sbjct: 246 RVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTI 305
Query: 626 NVPLKD-GIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NVP G+ D Y F V+ F+P +++ G D+L GD G + G A
Sbjct: 306 NVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQ 365
Query: 449 CVKTVMSYNIPMLVLG-GGGYTIR 381
+M L+L GGY +R
Sbjct: 366 LTHLLMGLAGGKLILSLEGGYNLR 389
Score = 62.8 bits (150), Expect = 3e-09
Identities = 44/153 (28%), Positives = 75/153 (48%), Gaps = 6/153 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
R++ +D DVHHG+G + F V+ S+H + FP GA + G G + V
Sbjct: 642 RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTV 701
Query: 626 NVPLKDG-IDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NV + D Y ++++V F P +++ G D+ GD LG +S +G+A+
Sbjct: 702 NVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAH 761
Query: 449 CVKTVMSYNIPMLVL-GGGGYTIRNVSRTWAYETGVICG 336
+M ++L GGY + ++S + A T + G
Sbjct: 762 LTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG 800
>gi|4240291|dbj|BAA74924| (AB020708) KIAA0901 protein [Homo sapiens]
Length = 1215
Score = 64.4 bits (154), Expect = 9e-10
Identities = 45/138 (32%), Positives = 65/138 (46%), Gaps = 6/138 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALN--DTGILKGKNYAV 627
RV+ +D DVHHG G + F V+ S+H +P A N TG +G+ Y +
Sbjct: 246 RVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQGQGYTI 305
Query: 626 NVPLKD-GIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NVP G+ D Y F V+ F+P +++ G D+L GD G + G A
Sbjct: 306 NVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATPAGFAQ 365
Query: 449 CVKTVMSYNIPMLVLG-GGGYTIR 381
+M L+L GGY +R
Sbjct: 366 LTHLLMGLAGGKLILSLEGGYNLR 389
Score = 62.8 bits (150), Expect = 3e-09
Identities = 44/153 (28%), Positives = 75/153 (48%), Gaps = 6/153 (3%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFP--GTGALNDTGILKGKNYAV 627
R++ +D DVHHG+G + F V+ S+H + FP GA + G G + V
Sbjct: 642 RILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIGRAAGTGFTV 701
Query: 626 NVPLKDG-IDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHAN 450
NV + D Y ++++V F P +++ G D+ GD LG +S +G+A+
Sbjct: 702 NVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDPLGGCQVSPEGYAH 761
Query: 449 CVKTVMSYNIPMLVL-GGGGYTIRNVSRTWAYETGVICG 336
+M ++L GGY + ++S + A T + G
Sbjct: 762 LTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLG 800
>gi|3023317|sp|Q48935|APHA_MYCRA ACETYLPOLYAMINE AMINOHYDROLASE >gi|520593|dbj|BAA01256| (D10463)
acetylpolyamine aminohydolase [Mycoplana ramosa]
Length = 341
Score = 57.4 bits (136), Expect = 1e-07
Identities = 36/140 (25%), Positives = 62/140 (43%), Gaps = 2/140 (1%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRVM--SVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
++ +D+D HHG+G ++ FY V S+H E G +TG G N
Sbjct: 188 KIAILDVDFHHGNGTQDIFYERGDVFFASLHGDPAEAFPHFLGYAEETGKGAGAGTTANY 247
Query: 620 PLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHANCVK 441
P+ G + + K I F IV+ G D+ D + F L++ + +
Sbjct: 248 PMGRGTPYSVWGEALTDSL-KRIAAFGAEAIVVSLGVDTFEQDPISFFKLTSPDYITMGR 306
Query: 440 TVMSYNIPMLVLGGGGYTIRNV 375
T+ + +P+LV+ GGY + +
Sbjct: 307 TIAASGVPLLVVMEGGYGVPEI 328
>gi|669045|emb|CAA78369| (Z13965) Portion of hypothetical protein [Synechococcus PCC7002]
Length = 278
Score = 57.4 bits (136), Expect = 1e-07
Identities = 37/138 (26%), Positives = 64/138 (45%), Gaps = 4/138 (2%)
Query: 803 ITSRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
+ R++ +D+DVH GDG F V + ++ E FP +D ++
Sbjct: 126 LAQRILIVDLDVHQGDGTAFIFQDDPTVFTFS-MHCEVNFPSQKQRSD----------LD 174
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKG----H 456
+ L +G+DD+ Y I +E + KP+ + G D+ GDRLG ++ G
Sbjct: 175 LGLPEGLDDDGYLQILAHHLEDLLSQVKPDLVFYDAGVDTHVGDRLGKLAMTNTGLYRRE 234
Query: 455 ANCVKTVMSYNIPMLVLGGGGY 390
+ T ++ P+ + GGGY
Sbjct: 235 RLVLSTCLAAGYPVACVIGGGY 256
>gi|669044|emb|CAA78368| (Z13965) Portion of hypothetical protein [Synechococcus PCC7002]
Length = 300
Score = 57.4 bits (136), Expect = 1e-07
Identities = 37/138 (26%), Positives = 64/138 (45%), Gaps = 4/138 (2%)
Query: 803 ITSRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
+ R++ +D+DVH GDG F V + ++ E FP +D ++
Sbjct: 148 LAQRILIVDLDVHQGDGTAFIFQDDPTVFTFS-MHCEVNFPSQKQRSD----------LD 196
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKG----H 456
+ L +G+DD+ Y I +E + KP+ + G D+ GDRLG ++ G
Sbjct: 197 LGLPEGLDDDGYLQILAHHLEDLLSQVKPDLVFYDAGVDTHVGDRLGKLAMTNTGLYRRE 256
Query: 455 ANCVKTVMSYNIPMLVLGGGGY 390
+ T ++ P+ + GGGY
Sbjct: 257 RLVLSTCLAAGYPVACVIGGGY 278
>gi|140712|sp|P28606|YGLA_SYNP2 HYPOTHETICAL 34.1 KD PROTEIN IN GLNA 3'REGION
>gi|1075598|pir||B47050 glnA 3'-region hypothetical
protein - Synechococcus sp >gi|580726|emb|CAA78367|
(Z13965) Portion of hypothetical protein [Synechococcus
PCC7002]
Length = 310
Score = 57.4 bits (136), Expect = 1e-07
Identities = 37/138 (26%), Positives = 64/138 (45%), Gaps = 4/138 (2%)
Query: 803 ITSRVMYIDIDVHHGDGVEEAFYTSDRVMSVHFINMENIFPGTGALNDTGILKGKNYAVN 624
+ R++ +D+DVH GDG F V + ++ E FP +D ++
Sbjct: 158 LAQRILIVDLDVHQGDGTAFIFQDDPTVFTFS-MHCEVNFPSQKQRSD----------LD 206
Query: 623 VPLKDGIDDESYEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKG----H 456
+ L +G+DD+ Y I +E + KP+ + G D+ GDRLG ++ G
Sbjct: 207 LGLPEGLDDDGYLQILAHHLEDLLSQVKPDLVFYDAGVDTHVGDRLGKLAMTNTGLYRRE 266
Query: 455 ANCVKTVMSYNIPMLVLGGGGY 390
+ T ++ P+ + GGGY
Sbjct: 267 RLVLSTCLAAGYPVACVIGGGY 288
>gi|854536|emb|CAA86368| (Z46259) RPD3 gene [Saccharomyces cerevisiae]
>gi|2253190|emb|CAA96262| (Z71605) ORF YNL330c
[Saccharomyces cerevisiae]
Length = 201
Score = 50.8 bits (119), Expect = 1e-05
Identities = 21/23 (91%), Positives = 23/23 (99%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSD 726
RV+YIDIDVHHGDGVEEAFYT+D
Sbjct: 179 RVLYIDIDVHHGDGVEEAFYTTD 201
>gi|3979814|emb|CAA90401| (Z50070) similar to transcriptional regulatory protein (RPD3); cDNA
EST EMBL:D70592 comes from this gene; cDNA EST
EMBL:D66697 comes from this gene; cDNA EST yk443e6.3
comes from this gene; cDNA EST yk443e6.5 comes from this
ge...
Length = 782
Score = 37.9 bits (86), Expect = 0.086
Identities = 40/161 (24%), Positives = 70/161 (42%), Gaps = 7/161 (4%)
Query: 794 RVMYIDIDVHHGDGVEEAFYTSDRV--MSVHFINMENIFPGTGALNDTGILKGKNYAVNV 621
+V +D D H G+G ++ R+ S H + +P + D + V
Sbjct: 438 KVAIVDFDYHAGNGTYQSVKDESRIHLTSFHGHHFGAFWPFS---RDYDYATNSQNTLFV 494
Query: 620 PLKDGIDDES-YEYIFNQVVEKAIRTFKPNTIVLQCGADSLSGDRLGCFNLSTKGHA-NC 447
PL ++ E Y +F+ V+ + F+P I++ G DS D + F K H
Sbjct: 495 PLNGTMNSEGDYVSVFHHVLLPMLEQFQPELILISAGFDSGYYDVMMEFGQGVKAHGYGH 554
Query: 446 VKTVMSYNIP--MLVLGGGGYTIRNVSRTWAYETGVICGVKLPE-DIP 312
+ ++S P +L + GGY N + + + + + LP DIP
Sbjct: 555 MARLLSQICPGKILAILEGGYHPYNYTESASMMVRGLLNLPLPRLDIP 602
>gi|2315555 (AF016657) C16C4.7 [Caenorhabditis elegans]
Length = 361
Score = 34.4 bits (77), Expect = 0.97
Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 460 PFVDKLKQPSLSPDNESAPHWSTMVFGLNVRIAFSTT*LKIYSY----DSSSIPSFNGTF 627
PF KQ NE+ + F LN R FS T +Y Y +SIP FN T
Sbjct: 31 PFCFLHKQQKKKTSNETCKYRENSTFTLNARSNFSKT---LYKYRENVPKNSIPIFNKT- 86
Query: 628 TA*FFPFKIPVSFKAPVPGKIFSI 699
P ++PV+F G+I SI
Sbjct: 87 -----PIRLPVNF-----GRISSI 100
>gi|1076557|pir||S54157 extensin-like protein - cowpea (fragment)
Length = 279
Score = 32.8 bits (73), Expect = 2.9
Identities = 16/61 (26%), Positives = 30/61 (48%)
Query: 590 MIHHQYHLSMEHSQHNFFLLKFLYHSKLPFQGKYSPYL*NEQT*PYRRYKKLLQHHHHGV 769
++HH H+ + H +H+ L+H L F + +L P+ + + +HHHH +
Sbjct: 3 LLHHHLHMCISHHRHHL-----LHHHLLMFTSHHLLHLL-----PHHLHMCISRHHHHLL 52
Query: 770 H 772
H
Sbjct: 53 H 53
>gi|2494726|sp|Q91513|PRLR_ORENI PROLACTIN RECEPTOR PRECURSOR (PRL-R) >gi|2134019|pir||I51086
prolactin receptor - Nile tilapia >gi|903847 (L34783)
prolactin receptor [Tilapia nilotica]
Length = 630
Score = 31.7 bits (70), Expect = 6.4
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 370 LDTFLIVYPPPPSTNIGIL*LITVLTQLAWPFVDKLKQPSLSPDNESAPHWSTMVFGLNV 549
+D IV P PP +TV+ WPF+ +P D S W T+++ L V
Sbjct: 120 IDVVYIVQPHPPEKLE-----VTVMKDQGWPFLRVSWEPPRKADTRSG--WITLIYELRV 172
Query: 550 RI 555
++
Sbjct: 173 KL 174
>gi|3880316|emb|CAB03443| (Z81133) Similarity to C.elegans mechanosensory protein
(WP:E02H4.1) [Caenorhabditis elegans]
Length = 548
Score = 31.3 bits (69), Expect = 8.4
Identities = 15/37 (40%), Positives = 23/37 (61%), Gaps = 7/37 (18%)
Query: 392 YTIRNVSRT-------WAYETGVICGVKLPEDIPYNEYFEHFGP 282
Y +R V RT W +GVI + + ++IPY + F +F P
Sbjct: 227 YGLRMVMRTDQDTYLPWTEASGVIIDIHMQDEIPYPDVFGYFAP 270
>gi|133320|sp|P22138|RPA2_YEAST DNA-DIRECTED RNA POLYMERASE I 135 KD POLYPEPTIDE (A135) (RNA
POLYMERASE I SUBUNIT 2) >gi|101446|pir||A39607
DNA-directed RNA polymerase (EC 2.7.7.6) I 135K chain -
yeast (Saccharomyces cerevisiae) >gi|172464 (M62804) RNA
polymerase I (second largest subunit) [Saccharomyces
cerevisiae] >gi|887587|emb|CAA90154| (Z49919) Rpa2p
[Saccharomyces cerevisiae] >gi|939744 (U31900) Rpa135p
[Saccharomyces cerevisiae] >gi|1314085|emb|CAA95050|
(Z71255) Rpa2p [Saccharomyces cerevisiae]
Length = 1203
Score = 31.3 bits (69), Expect = 8.4
Identities = 27/117 (23%), Positives = 54/117 (46%), Gaps = 3/117 (2%)
Query: 539 PNTIVLQCGADSLSGDRLGCFNLSTKGHANCVKTVMSYNIPMLVLGGGGYTIRNVSRTWA 360
P+ L+ G + L DR+ +L G + + ++ + L G + N T
Sbjct: 342 PDQSDLEVGQEVL--DRIVLVHLGKDGSQDKFRMLLFMIRKLYSLVAGECSPDNPDATQH 399
Query: 359 YET---GVICGVKLPEDIPYNEYFEHFGPDYKINVLSGNMKNYNDRKYLDNIIKTVTENL 189
E G + G+ L E I +EY ++ ++++ G N+ D++Y+ ++ V EN+
Sbjct: 400 QEVLLGGFLYGMILKEKI--DEYLQNIIAQVRMDINRGMAINFKDKRYMSRVLMRVNENI 457
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 17, 1999 5:33 AM
Number of letters in database: 113,023,754
Number of sequences in database: 369,800
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 165104692
Number of Sequences: 369800
Number of extensions: 3627605
Number of successful extensions: 10735
Number of sequences better than 10.0: 144
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 10572
Number of HSP's gapped (non-prelim): 83
length of query: 269
length of database: 113023754
effective HSP length: 54
effective length of query: 214
effective length of database: 93054554
effective search space: 19913674556
effective search space used: 19913674556
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 68 (30.9 bits)