BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 12VII19R
(748 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
368,476 sequences; 112,640,273 total letters
Searching...................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|2827086 (AF022778) DNA recombination and repair protein [Homo... 198 3e-50
gi|1388175 (U58987) endo/exonuclease Mre11 [Mus musculus] 198 4e-50
gi|1401337 (U60318) Mre11b [Mus musculus] 198 4e-50
gi|1709095|sp|P49959|MR11_HUMAN MRE11 HOMOLOG 197 9e-50
gi|3912938 (U37359) MRE11 homologue hMre11 [Homo sapiens] 197 9e-50
gi|1172822|sp|Q09683|RA32_SCHPO DNA REPAIR PROTEIN RAD32 >gi|213... 196 2e-49
gi|809603|emb|CAA57765| (X82322) rad32 [Schizosaccharomyces pombe] 193 1e-48
gi|3434965|dbj|BAA32417| (AB002530) mus-23 [Neurospora crassa] 190 8e-48
gi|1709096|sp|P32829|MR11_YEAST MRE11 PROTEIN >gi|1362425|pir||S... 180 9e-45
gi|2209265 (U60829) Mre11p [Saccharomyces cerevisiae] 180 9e-45
gi|3881390|emb|CAA98292| (Z73978) predicted using Genefinder; Si... 171 4e-42
gi|3257343|dbj|BAA30026| (AP000004) 413aa long hypothetical prot... 60 2e-08
gi|2649563 (AE001032) DNA repair protein RAD32 (rad32) [Archaeog... 58 8e-08
gi|2128792|pir||B64465 hypothetical protein MJ1323 - Methanococc... 42 0.005
gi|2621616 (AE000837) Rad32 related protein [Methanobacterium th... 41 0.012
gi|3914943|sp|O51769|SBCD_BORBU EXONUCLEASE SBCD HOMOLOG >gi|268... 36 0.23
gi|1657594 (U73857) exonuclease SbcD [Escherichia coli] 36 0.39
gi|140195|sp|P13457|SBCD_ECOLI EXONUCLEASE SBCD >gi|78529|pir||J... 36 0.39
gi|3257732|dbj|BAA30415| (AP000006) 228aa long hypothetical prot... 33 2.0
gi|4155727 (AE001541) putative role in outermembrane permeabilit... 33 2.0
gi|1170472|sp|P44685|ICC_HAEIN ICC PROTEIN HOMOLOG >gi|1074958|p... 33 2.6
gi|4493965|emb|CAB39024| (AL034559) predicted using hexExon; MAL... 32 5.9
gi|3123089|sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|... 32 5.9
gi|3915647|sp|P05501|CYB_SCHPO CYTOCHROME B >gi|2654247|emb|CAA3... 31 7.7
gi|3845169 (AE001391) phosphatase (acid phosphatase family) [Pla... 31 7.7
>gi|2827086 (AF022778) DNA recombination and repair protein [Homo sapiens]
>gi|3328152 (AF073362) endo/exonuclease Mre11 [Homo
sapiens]
Length = 708
Score = 198 bits (499), Expect = 3e-50
Identities = 93/197 (47%), Positives = 139/197 (70%), Gaps = 13/197 (6%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFN 336
KIL+ +D HLG+ E D ++G D+F+T +EIL++A + VD ++ GGDLFH NKPSR T +
Sbjct: 14 KILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLH 73
Query: 337 RTINLLKKYCLGDKEIKIETNTQ------------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ LL+KYC+GD+ ++ E + + Y D NLNI +P+ +IHGNHDDP
Sbjct: 74 TCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPT 133
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G +L ALDIL +G + + G+ +++KI+I+P+LL T +ALY LG I D RL+R F
Sbjct: 134 GADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMF 193
Query: 661 LEGKISYLRP-NNYKEYFNILVLHQNPSKY 747
+ K++ LRP + +FN+ V+HQN SK+
Sbjct: 194 VNKKVTMLRPKEDENSWFNLFVIHQNRSKH 223
>gi|1388175 (U58987) endo/exonuclease Mre11 [Mus musculus]
Length = 706
Score = 198 bits (498), Expect = 4e-50
Identities = 92/197 (46%), Positives = 140/197 (70%), Gaps = 13/197 (6%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFN 336
KIL+ +D HLG+ E D ++G D+F+TF+EIL++A + VD ++ GGDLFH NKPSR T +
Sbjct: 14 KILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRKTLH 73
Query: 337 RTINLLKKYCLGDKEIKIETNTQ------------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ LL+KYC+GD+ ++ E + + Y D NLNI +P+ +IHGNHDDP
Sbjct: 74 SCLELLRKYCMGDRPVQFEVISDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPT 133
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G +L ALD+L +G + + G+ +++K++I+P+LL T +ALY LG I D RL+R F
Sbjct: 134 GADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDERLYRMF 193
Query: 661 LEGKISYLRP-NNYKEYFNILVLHQNPSKY 747
+ K++ LRP + +FN+ V+HQN SK+
Sbjct: 194 VNKKVTMLRPKEDENSWFNLFVIHQNRSKH 223
>gi|1401337 (U60318) Mre11b [Mus musculus]
Length = 679
Score = 198 bits (498), Expect = 4e-50
Identities = 92/197 (46%), Positives = 140/197 (70%), Gaps = 13/197 (6%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFN 336
KIL+ +D HLG+ E D ++G D+F+TF+EIL++A + VD ++ GGDLFH NKPSR T +
Sbjct: 14 KILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGDLFHENKPSRKTLH 73
Query: 337 RTINLLKKYCLGDKEIKIETNTQ------------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ LL+KYC+GD+ ++ E + + Y D NLNI +P+ +IHGNHDDP
Sbjct: 74 SCLELLRKYCMGDRPVQFEVISDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPT 133
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G +L ALD+L +G + + G+ +++K++I+P+LL T +ALY LG I D RL+R F
Sbjct: 134 GADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYGLGSIPDERLYRMF 193
Query: 661 LEGKISYLRP-NNYKEYFNILVLHQNPSKY 747
+ K++ LRP + +FN+ V+HQN SK+
Sbjct: 194 VNKKVTMLRPKEDENSWFNLFVIHQNRSKH 223
>gi|1709095|sp|P49959|MR11_HUMAN MRE11 HOMOLOG
Length = 708
Score = 197 bits (495), Expect = 9e-50
Identities = 93/197 (47%), Positives = 138/197 (69%), Gaps = 13/197 (6%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFN 336
KIL+ +D HLG+ E D +G D+F+T +EIL++A + VD ++ GGDLFH NKPSR T +
Sbjct: 14 KILVATDIHLGFMEKDAARGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLH 73
Query: 337 RTINLLKKYCLGDKEIKIETNTQ------------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ LL+KYC+GD+ ++ E + + Y D NLNI +P+ +IHGNHDDP
Sbjct: 74 TCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPT 133
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G +L ALDIL +G + + G+ +++KI+I+P+LL T +ALY LG I D RL+R F
Sbjct: 134 GADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMF 193
Query: 661 LEGKISYLRP-NNYKEYFNILVLHQNPSKY 747
+ K++ LRP + +FN+ V+HQN SK+
Sbjct: 194 VNKKVTMLRPKEDENSWFNLFVIHQNRSKH 223
>gi|3912938 (U37359) MRE11 homologue hMre11 [Homo sapiens]
Length = 680
Score = 197 bits (495), Expect = 9e-50
Identities = 93/197 (47%), Positives = 138/197 (69%), Gaps = 13/197 (6%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFN 336
KIL+ +D HLG+ E D +G D+F+T +EIL++A + VD ++ GGDLFH NKPSR T +
Sbjct: 14 KILVATDIHLGFMEKDAARGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLH 73
Query: 337 RTINLLKKYCLGDKEIKIETNTQ------------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ LL+KYC+GD+ ++ E + + Y D NLNI +P+ +IHGNHDDP
Sbjct: 74 TCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPT 133
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G +L ALDIL +G + + G+ +++KI+I+P+LL T +ALY LG I D RL+R F
Sbjct: 134 GADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMF 193
Query: 661 LEGKISYLRP-NNYKEYFNILVLHQNPSKY 747
+ K++ LRP + +FN+ V+HQN SK+
Sbjct: 194 VNKKVTMLRPKEDENSWFNLFVIHQNRSKH 223
>gi|1172822|sp|Q09683|RA32_SCHPO DNA REPAIR PROTEIN RAD32 >gi|2130472|pir||S58097 Rad32 protein -
fission yeast (Schizosaccharomyces pombe)
>gi|908896|emb|CAA90458| (Z50112) Rad32p dna repair
protein [Schizosaccharomyces pombe]
Length = 649
Score = 196 bits (492), Expect = 2e-49
Identities = 96/198 (48%), Positives = 143/198 (71%), Gaps = 13/198 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
++ILI+SD H+GY E DP++G DSF++F EIL+IA + +VD+++ GGD+FH NKPSR
Sbjct: 18 IRILISSDPHVGYGEKDPVRGNDSFVSFNEILEIARERDVDMILLGGDIFHDNKPSRKAL 77
Query: 334 NRTINLLKKYCLGDK--EIKIETNTQLT----------YHDDNLNIKMPIIAIHGNHDDP 477
+ + L+ CLGDK E+++ ++T LT Y D N+N+ +P+ +IHGNHDDP
Sbjct: 78 YQALRSLRLNCLGDKPCELELLSDTSLTTGDTAVCNINYLDPNINVAIPVFSIHGNHDDP 137
Query: 478 CGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRT 657
G G SALDIL +GL+ Y G+ D I ++PILL T +ALY + ++D RL+ +
Sbjct: 138 SGDGRYSALDILQVTGLVNYFGRVPENDNIVVSPILLQKGFTKLALYGISNVRDERLYHS 197
Query: 658 FLEGKISYLRPNNYK-EYFNILVLHQNPSKY 747
F E K+ +LRP+ Y+ E+FN+L +HQN S +
Sbjct: 198 FRENKVKFLRPDLYRDEWFNLLTVHQNHSAH 228
>gi|809603|emb|CAA57765| (X82322) rad32 [Schizosaccharomyces pombe]
Length = 478
Score = 193 bits (485), Expect = 1e-48
Identities = 95/198 (47%), Positives = 142/198 (70%), Gaps = 13/198 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
++ILI+SD H+GY E DP++G DSF++F EIL+IA + +VD+++ GGD+FH NKPSR
Sbjct: 18 IRILISSDPHVGYGEKDPVRGNDSFVSFNEILEIARERDVDMILLGGDIFHDNKPSRKAL 77
Query: 334 NRTINLLKKYCLGDK--EIKIETNTQLT----------YHDDNLNIKMPIIAIHGNHDDP 477
+ + L+ CLGDK E+++ ++T LT Y D N+N+ +P+ +IHGNHDDP
Sbjct: 78 YQALRSLRLNCLGDKPCELELLSDTSLTTGDTAVCNINYLDPNINVAIPVFSIHGNHDDP 137
Query: 478 CGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRT 657
G G SALDIL +GL+ Y G+ D I ++PILL T +ALY + ++D RL+ +
Sbjct: 138 SGDGRYSALDILQVTGLVNYFGRVPENDNIVVSPILLQKGFTKLALYGISNVRDERLYHS 197
Query: 658 FLEGKISYLRPNNYK-EYFNILVLHQNPSKY 747
F E K+ +LRP+ Y+ E+ N+L +HQN S +
Sbjct: 198 FRENKVKFLRPDLYRDEWVNLLTVHQNHSAH 228
>gi|3434965|dbj|BAA32417| (AB002530) mus-23 [Neurospora crassa]
Length = 525
Score = 190 bits (478), Expect = 8e-48
Identities = 88/194 (45%), Positives = 137/194 (70%), Gaps = 12/194 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
++IL+++DNH+GY E P++ +DS+ TF+EI++IA K++VD+++ GGDLFH NKPSR +
Sbjct: 30 IRILVSTDNHVGYAERHPVRKDDSWRTFDEIMQIAKKQDVDMVLLGGDLFHENKPSRKSM 89
Query: 334 NRTINLLKKYCLGDKEIKIETNTQ-----------LTYHDDNLNIKMPIIAIHGNHDDPC 480
+ + L+K+CLG K ++E + + Y D ++N+ +P+ +IHGNHDDP
Sbjct: 90 YQVMRSLRKHCLGMKPCELEFLSDAAEVFEGAFPFVNYEDPDINVAIPVFSIHGNHDDPS 149
Query: 481 GLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTF 660
G G +LD+L +GL+ Y G+ D I + PILL T +ALY L ++D R+HRTF
Sbjct: 150 GDGHYCSLDLLQAAGLVNYFGRVPEADNIHVKPILLQKGRTKMALYGLSNVRDERMHRTF 209
Query: 661 LEGKISYLRPNNYK-EYFNILVLHQN 735
+ K+ + RPN K ++FN+L LHQN
Sbjct: 210 RDNKVRFYRPNQQKNDWFNLLALHQN 235
>gi|1709096|sp|P32829|MR11_YEAST MRE11 PROTEIN >gi|1362425|pir||S57592 MRE11 protein - yeast
(Saccharomyces cerevisiae) >gi|887605|emb|CAA90195|
(Z49939) Mre11p [Saccharomyces cerevisiae]
>gi|1513065|dbj|BAA02017| (D11463) Mre11 [Saccharomyces
cerevisiae]
Length = 692
Score = 180 bits (452), Expect = 9e-45
Identities = 87/194 (44%), Positives = 130/194 (66%), Gaps = 13/194 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
++ILIT+DNH+GY E+DPI G+DS+ TF E++ +A NVD+++Q GDLFH+NKPS+ +
Sbjct: 9 IRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSL 68
Query: 334 NRTINLLKKYCLGDKEIKIE------------TNTQLTYHDDNLNIKMPIIAIHGNHDDP 477
+ + L+ C+GDK ++E T + Y D N NI +P+ I GNHDD
Sbjct: 69 YQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISGNHDDA 128
Query: 478 CGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRT 657
G L +DILH +GLI + GK DKI++ P+L T +ALY L ++D RL RT
Sbjct: 129 SGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRT 188
Query: 658 FLEGKISYLRPNNYK-EYFNILVLHQN 735
F +G +++ P + E+FN++ +HQN
Sbjct: 189 FKDGGVTFEVPTMREGEWFNLMCVHQN 215
>gi|2209265 (U60829) Mre11p [Saccharomyces cerevisiae]
Length = 692
Score = 180 bits (452), Expect = 9e-45
Identities = 87/194 (44%), Positives = 130/194 (66%), Gaps = 13/194 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
++ILIT+DNH+GY E+DPI G+DS+ TF E++ +A NVD+++Q GDLFH+NKPS+ +
Sbjct: 9 IRILITTDNHVGYNENDPITGDDSWKTFHEVMMLAKNNNVDMVVQSGDLFHVNKPSKKSL 68
Query: 334 NRTINLLKKYCLGDKEIKIE------------TNTQLTYHDDNLNIKMPIIAIHGNHDDP 477
+ + L+ C+GDK ++E T + Y D N NI +P+ I GNHDD
Sbjct: 69 YQVLKTLRLCCMGDKPCELELLSDPSQVFHYDEFTNVNYEDPNFNISIPVFGISGNHDDA 128
Query: 478 CGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRT 657
G L +DILH +GLI + GK DKI++ P+L T +ALY L ++D RL RT
Sbjct: 129 SGDSLLCPMDILHATGLINHFGKVIESDKIKVVPLLFQKGSTKLALYGLAAVRDERLFRT 188
Query: 658 FLEGKISYLRPNNYK-EYFNILVLHQN 735
F +G +++ P + E+FN++ +HQN
Sbjct: 189 FKDGGVTFEVPTMREGEWFNLMCVHQN 215
>gi|3881390|emb|CAA98292| (Z73978) predicted using Genefinder; Similarity to Human MRE11
protein (TR:G1049320); cDNA EST EMBL:D65231 comes from
this gene; cDNA EST EMBL:D68586 comes from this gene;
cDNA EST yk323f11.3 comes from this gene; cDNA EST
yk32...
Length = 772
Score = 171 bits (430), Expect = 4e-42
Identities = 92/194 (47%), Positives = 129/194 (66%), Gaps = 13/194 (6%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTF 333
+KIL+ +D H GY E+ D+ TFEE+L+IA ++ VD+++ GGDLFH N PSR
Sbjct: 110 IKILVATDIHCGYGENKANIHMDAVNTFEEVLQIATEQKVDMILLGGDLFHENNPSREVQ 169
Query: 334 NRTINLLKKYCLGDKEIKIETNT------------QLTYHDDNLNIKMPIIAIHGNHDDP 477
+R LL++YCL I +E + + Y+D NLN+ +PI IHGNHDD
Sbjct: 170 HRVTQLLRQYCLNGNPIALEFLSDASVNFNQSVFGHVNYYDQNLNVGLPIFTIHGNHDDL 229
Query: 478 CGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRT 657
G G L+ALD+LH SGL+ GK +N+ + ++PILL ET +ALY +G +D RL R
Sbjct: 230 SGKG-LTALDLLHESGLVNLFGKHSNIQEFIVSPILLRKGETRLALYGIGSQRDDRLVRA 288
Query: 658 FLEGKISYLRPN-NYKEYFNILVLHQN 735
F IS+LRPN +++FN+ VLHQN
Sbjct: 289 FKNNSISFLRPNAGAEDWFNLFVLHQN 315
>gi|3257343|dbj|BAA30026| (AP000004) 413aa long hypothetical protein [Pyrococcus horikoshii]
Length = 413
Score = 59.7 bits (142), Expect = 2e-08
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 7/193 (3%)
Query: 154 MKILITSDNHLGYKE-SDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYT 330
MK +D HLGY++ + P + E+ TF++ L++ KE+VD +I GDLF+ ++PS T
Sbjct: 1 MKFAHLADVHLGYEQFNKPQRAEEFANTFKKALEMCVKESVDFIIIAGDLFNSSRPSPGT 60
Query: 331 FNRTINLLKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHDDPCGLGSLSALDI 510
I LL +I E N +P+ AI GNHD S L +
Sbjct: 61 IKTAIKLL--------QIPKENN-------------IPVFAIEGNHDRT--QRGPSVLHL 97
Query: 511 LHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLH------RTFLEGK 672
L GL+ +G L + + LT E + G + +H + E
Sbjct: 98 LEDLGLLYVIG----LRQERVENEYLTSERVGNYWLVKGVYDNLEIHGMKYMSSAWFEAN 153
Query: 673 ISYLRPNNYKEYFNILVLHQ 732
+++ + + ILVLHQ
Sbjct: 154 LNFFKGIFRPDEDAILVLHQ 173
>gi|2649563 (AE001032) DNA repair protein RAD32 (rad32) [Archaeoglobus
fulgidus]
Length = 443
Score = 57.8 bits (137), Expect = 8e-08
Identities = 53/193 (27%), Positives = 90/193 (46%), Gaps = 10/193 (5%)
Query: 154 MKILITSDNHLGYKE-SDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYT 330
MK +D HLGY++ + P + ED F+ I + A + N D ++ GDLFH + PS T
Sbjct: 1 MKFAHIADVHLGYEQYNQPWRAEDFAKAFKVIAEKAVESNADFVVIAGDLFHRSLPSPRT 60
Query: 331 FNRTINLLKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHDDPCGLGSLSALDI 510
IK T + +N+ P+ A+ GNHD +SA +
Sbjct: 61 -----------------IKEAVETLWMFRKENI----PVFAVEGNHDKTS--RDISAYHL 97
Query: 511 LHTSGLITYVG------KCTNLDKIEINPILL---TIEETNVALYMLGYIKDARLHRTFL 663
L + GL+ +G + N++ + I + L +++ + + D + L
Sbjct: 98 LESLGLLNVLGLRRNPVRGENVESLRIQNVYLVKGVVDDVEI-------LGDRHRSKWQL 150
Query: 664 EGKISYLRPNNYKEYFNILVLHQ 732
E + L+P + K ++LVLHQ
Sbjct: 151 EKVLPLLKPQSDK---SVLVLHQ 170
>gi|2128792|pir||B64465 hypothetical protein MJ1323 - Methanococcus jannaschii >gi|1591963
(U67572) DNA repair protein RAD32 (rad32) [Methanococcus
jannaschii]
Length = 366
Score = 41.8 bits (96), Expect = 0.005
Identities = 53/198 (26%), Positives = 83/198 (41%), Gaps = 1/198 (0%)
Query: 154 MKILITSDNHLGYKESDPIQGE-DSFITFEEILKIADKENVDILIQGGDLFHINKPSRYT 330
M + +DNHLGY++ + E D + +F+ +K + D+++ GDLF+ +P
Sbjct: 1 MMFVHIADNHLGYRQYNLDDREKDIYDSFKLCIKKILEIKPDVVLHSGDLFNDLRPPVKA 60
Query: 331 FNRTINLLKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHDDPCGLGSLSALDI 510
+ KK H++ NIK+ I+A GNH+ P LG S L +
Sbjct: 61 LRIAMQAFKK-----------------LHEN--NIKVYIVA--GNHEMPRRLGEESPLAL 99
Query: 511 LHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTFLEGKISYLRP 690
L YV D I +N + I T Y K ++ + K
Sbjct: 100 LK-----DYVKILDGKDVINVNGEEIFICGTY-------YHKKSKREEMLDKLKNFESEA 147
Query: 691 NNYKEYFNILVLHQNPSKY 747
NYK+ IL+LHQ + Y
Sbjct: 148 KNYKK--KILMLHQGINPY 164
>gi|2621616 (AE000837) Rad32 related protein [Methanobacterium
thermoautotrophicum]
Length = 587
Score = 40.6 bits (93), Expect = 0.012
Identities = 36/123 (29%), Positives = 54/123 (43%)
Query: 172 SDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYTFNRTINL 351
SD HLG ++ ++ E F F L A +++VD +I GDLFH N P+ T R
Sbjct: 177 SDCHLGAQKHPDLR-ELEFEAFRMALDDALQKDVDFMIIAGDLFHSNIPNMETVKRATLE 235
Query: 352 LKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHDDPCGLGSLSALDILHTSGLI 531
L++ +PI +G+HD S S +DIL ++G+I
Sbjct: 236 LRRV---------------------REAGVPIYVNYGSHD--YSPSSTSMIDILESAGVI 272
Query: 532 TYV 540
V
Sbjct: 273 DKV 275
>gi|3914943|sp|O51769|SBCD_BORBU EXONUCLEASE SBCD HOMOLOG >gi|2688778 (AE001181) exonuclease SbcD
(sbcD) [Borrelia burgdorferi]
Length = 413
Score = 36.4 bits (82), Expect = 0.23
Identities = 20/54 (37%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
Query: 157 KILITSDNHLGYKESD--PIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKP 318
KIL TSD H+G K + ++ + +F+ F +L+ KEN+D+L+ GD++ +P
Sbjct: 5 KILHTSDWHIGKKIENFSILKEQKNFLYF--LLEFIKKENIDLLLVAGDVYDSKRP 58
>gi|1657594 (U73857) exonuclease SbcD [Escherichia coli]
Length = 408
Score = 35.6 bits (80), Expect = 0.39
Identities = 24/71 (33%), Positives = 35/71 (48%), Gaps = 4/71 (5%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYT- 330
M+IL TSD HLG + + + +L+ A VD +I GD+F P Y
Sbjct: 9 MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYAR 68
Query: 331 --FNR-TINLLKKYC 366
+NR +NL + C
Sbjct: 69 TLYNRFVVNLQQTGC 83
>gi|140195|sp|P13457|SBCD_ECOLI EXONUCLEASE SBCD >gi|78529|pir||JS0349 hypothetical 45K protein
(sbcC 5' region) - Escherichia coli
>gi|42913|emb|CAA34103| (X15981) ORF 45 peptide (AA
1-400) [Escherichia coli] >gi|1786598 (AE000146)
ATP-dependent dsDNA exonuclease [Escherichia coli]
>gi|1586770|prf||2204364B sbcD gene [Escherichia coli]
Length = 400
Score = 35.6 bits (80), Expect = 0.39
Identities = 24/71 (33%), Positives = 35/71 (48%), Gaps = 4/71 (5%)
Query: 154 MKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKENVDILIQGGDLFHINKPSRYT- 330
M+IL TSD HLG + + + +L+ A VD +I GD+F P Y
Sbjct: 1 MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYAR 60
Query: 331 --FNR-TINLLKKYC 366
+NR +NL + C
Sbjct: 61 TLYNRFVVNLQQTGC 75
>gi|3257732|dbj|BAA30415| (AP000006) 228aa long hypothetical protein [Pyrococcus horikoshii]
Length = 228
Score = 33.2 bits (74), Expect = 2.0
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 157 KILITSDNHLGYKESDPIQGEDSFI------TFEEILKIADKENVDILIQGGDLFHINKP 318
K+L+ +D H+G++ES IQG +I ++ IA EN LI GDL H P
Sbjct: 15 KVLVLADIHIGFEES-AIQG-GMYIPKLLRDVIRDVKSIAMHENAKTLIINGDLKHSFTP 72
Query: 319 SRYTFNRTINLLKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHD 471
+ F L++ KE+ E +I + GNHD
Sbjct: 73 LKREFFEVGTFLREV----KEVVDE-----------------VILVKGNHD 102
>gi|4155727 (AE001541) putative role in outermembrane permeability
[Helicobacter pylori J99]
Length = 766
Score = 33.2 bits (74), Expect = 2.0
Identities = 37/138 (26%), Positives = 57/138 (40%), Gaps = 4/138 (2%)
Query: 334 NRTINLLKK---YCLGDKEIKIETNTQLTYHDDNLN-IKMPIIAIHGNHDDPCGLGSLSA 501
N+T+NL Y LG +E+ +QL DD ++ KMP+ + G L+
Sbjct: 565 NKTVNLTLTQYLYGLGGQELLYFKISQLINLDDKVSPFKMPL-------ESKIGFSPLTG 617
Query: 502 LDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDARLHRTFLEGKISY 681
L+I G + Y L++I +N A R FL +SY
Sbjct: 618 LNIF---GNVFYSFYQNRLEEISVN---------------------ANYQRKFLSFNLSY 653
Query: 682 LRPNNYKEYFNILVLHQNPSKY 747
NN+ N +V +NP+ Y
Sbjct: 654 FLRNNFSSGINSIV--ENPADY 673
>gi|1170472|sp|P44685|ICC_HAEIN ICC PROTEIN HOMOLOG >gi|1074958|pir||E64065 lacZ expression
regulator (icc) homolog - Haemophilus influenzae (strain
Rd KW20) >gi|1573370 (U32723) lacZ expression regulator
(icc) [Haemophilus influenzae Rd]
Length = 274
Score = 32.8 bits (73), Expect = 2.6
Identities = 24/86 (27%), Positives = 44/86 (50%), Gaps = 2/86 (2%)
Query: 106 NVFYF*IKKYIIYAFPMKILITSDNHLGYKESDPIQGEDSFITFEEILKIADKEN--VDI 279
N F + +K +I K+L +D HL ES + G ++ +F ++LK +EN D+
Sbjct: 3 NTFVYQAEKPVI-----KLLQITDPHLFKDESAELLGVNTQASFAQVLKEIQQENNEFDV 57
Query: 280 LIQGGDLFHINKPSRYTFNRTINLLKKY 363
++ GDL + Y R + ++K +
Sbjct: 58 ILATGDLVQDSSDEGYI--RFVEMMKPF 83
>gi|4493965|emb|CAB39024| (AL034559) predicted using hexExon; MAL3P7.4 (PFC0875w),
Hypothetical protein, len: 3004 aa [Plasmodium
falciparum]
Length = 3003
Score = 31.7 bits (70), Expect = 5.9
Identities = 31/130 (23%), Positives = 60/130 (45%), Gaps = 14/130 (10%)
Query: 325 YTFNRTINLLKKY-----CLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGN-------- 465
Y N +N+ K Y CL + + IE ++ + ++L + I+ IH N
Sbjct: 7 YAENNDLNIFKLYNSEEDCLKNLKYAIELKSEDFKNVNSLELNDDILNIHENDKNSLLYN 66
Query: 466 -HDDPCGLGSLSALDILHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLGYIKDA 642
H + L S S +I + + N+ ++INP +L + +K+
Sbjct: 67 LHTNIINLKS-SEFNINDLYKDVYTENEFENIKNLKINPHILKV------------VKNT 113
Query: 643 RLHRTFLEGKISYLRPNNYKEYFN 714
++ F++ + N+Y +YFN
Sbjct: 114 EFYKNFIKDIKNLKNENHYTQYFN 137
>gi|3123089|sp|Q58454|YA54_METJA HYPOTHETICAL PROTEIN MJ1054 >gi|2129344|pir||E64431 UDPglucose
6-dehydrogenase (intein-containing) - Methanococcus
jannaschii >gi|1591706 (U67548) UDP-glucose
dehydrogenase, putative [Methanococcus jannaschii]
Length = 895
Score = 31.7 bits (70), Expect = 5.9
Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 5/71 (7%)
Query: 229 ITFEEILKIADKENVDILIQGGDLFHINK----PSRYTFNRTINLLKKYCLGDKEIKI-E 393
ITF+E+ ++ DK+NV IL G+ + K RY + I L ++ LG +EIKI +
Sbjct: 279 ITFKELFELEDKDNVKILSFDGEKLSLKKLKLASKRYYNDDLITL--RFNLG-REIKITK 335
Query: 394 TNTQLTYHDDNLNIKM 441
+ + D L IK+
Sbjct: 336 DHPVVILEDGELKIKL 351
>gi|3915647|sp|P05501|CYB_SCHPO CYTOCHROME B >gi|2654247|emb|CAA38287| (X54421) cytochrome b
[Schizosaccharomyces pombe] >gi|4379182|emb|CAA26588|
(X02819) apocytochrome b [Schizosaccharomyces pombe]
Length = 387
Score = 31.3 bits (69), Expect = 7.7
Identities = 15/51 (29%), Positives = 30/51 (58%), Gaps = 2/51 (3%)
Query: 475 PCGLGSLSALDI--LHTSGLITYVGKCTNLDKIEINPILLTIEETNVALYMLG 627
P + +LS + + LHT+G +G N+D+I +NP L + + ++++G
Sbjct: 187 PFVIAALSVMHLIALHTNGSSNPLGVTANMDRIPMNPYYLIKDLITIFIFLIG 239
>gi|3845169 (AE001391) phosphatase (acid phosphatase family) [Plasmodium
falciparum]
Length = 2010
Score = 31.3 bits (69), Expect = 7.7
Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 7/50 (14%)
Query: 322 RYTFNRTI-------NLLKKYCLGDKEIKIETNTQLTYHDDNLNIKMPIIAIHGNHD 471
++TFN ++ L+KKY +G+K+ K E N YH+D N I + NHD
Sbjct: 1638 KFTFNNSVPLKLKKNKLIKKYNMGNKKDKEEDN---NYHNDKNNYSDNI--FYDNHD 1689
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 12, 1999 12:54 PM
Number of letters in database: 112,640,273
Number of sequences in database: 368,476
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139396364
Number of Sequences: 368476
Number of extensions: 2860589
Number of successful extensions: 7327
Number of sequences better than 10.0: 50
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 7281
Number of HSP's gapped (non-prelim): 34
length of query: 249
length of database: 112640273
effective HSP length: 53
effective length of query: 195
effective length of database: 93111045
effective search space: 18156653775
effective search space used: 18156653775
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 68 (30.9 bits)