BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 12VII-24R
(814 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
369,800 sequences; 113,023,754 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|1575575 (U66887) RAD50 [Mus musculus] 98 8e-20
gi|2687853|emb|CAA99729| (Z75311) RAD50 homologue hsRAD50 [Homo ... 96 3e-19
gi|1518806 (U63139) Rad50 [Homo sapiens] 96 3e-19
gi|4263721|gb|AAD15407| (AC006223) putative DNA repair protein R... 92 4e-18
gi|131782|sp|P12753|RA50_YEAST DNA REPAIR PROTEIN RAD50 (153 KD ... 91 7e-18
gi|2687855|emb|CAA99730| (Z75312) RAD50 homologue ceRAD50 [Caeno... 65 5e-10
gi|4493978|emb|CAB39037| (AL034559) predicted using hexExon; MAL... 39 0.038
gi|4049717 (AF063866) ORF MSV156 hypothetical protein [Melanoplu... 39 0.038
gi|3845107 (AE001375) hypothetical protein [Plasmodium falciparum] 37 0.15
gi|2129174|pir||A64505 P115 homolog - Methanococcus jannaschii 36 0.25
gi|2826443 (U67604) chromosome segretation protein (smc1) [Metha... 36 0.25
gi|729230|sp|P41004|CUT3_SCHPO CHROMOSOME SEGREGATION PROTEIN CU... 36 0.44
gi|1151158 (U43145) repeat organellar protein [Plasmodium chabaudi] 36 0.44
gi|2952522 (AF051357) golgin-245 [Mus musculus] 36 0.44
gi|2983515 (AE000718) hypothetical protein [Aquifex aeolicus] 34 0.98
gi|2128750|pir||E64456 hypothetical protein MJ1254 - Methanococc... 34 1.3
gi|285152|pir||S28061 SCP1 protein - rat >gi|57213|emb|CAA48006|... 34 1.7
gi|2895538 (AF036485) replication protein [Plasmid pNZ4000] 34 1.7
gi|3041729|sp|Q03410|SCP1_RAT SYNAPTONEMAL COMPLEX PROTEIN 1 (SC... 34 1.7
gi|4092846|dbj|BAA73535| (AB019987) chromosome-associated polype... 34 1.7
gi|2498896|sp|Q60563|SCP1_MESAU SYNAPTONEMAL COMPLEX PROTEIN 1 (... 33 2.2
gi|2496852|sp|Q11102|YL17_CAEEL HYPOTHETICAL 131.5 KD PROTEIN C0... 33 2.2
gi|4503469|oth|NP_003557|PEEA1 early endosome-associated protein... 33 2.9
gi|3256959|dbj|BAA29642| (AP000002) 399aa long hypothetical prot... 33 2.9
gi|2983243 (AE000699) chromosome assembly protein homolog [Aquif... 33 2.9
gi|4493894|emb|CAB39003| (AL034558) predicted using hexExon; MAL... 33 2.9
gi|631129|pir||S44243 endosomal protein - human >gi|475934|emb|C... 33 2.9
gi|3876121|emb|CAA92298| (Z68161) cDNA EST EMBL:C13248 comes fro... 32 3.8
gi|2128791|pir||A64465 hypothetical protein MJ1322 - Methanococc... 32 3.8
gi|2224697|dbj|BAA20832| (AB002376) KIAA0378 [Homo sapiens] 32 5.0
gi|2649562 (AE001032) purine NTPase, putative [Archaeoglobus ful... 32 5.0
gi|4249701 (AF097907) myosin heavy chain [Rana catesbeiana] 32 5.0
gi|4049801 (AF063866) ORF MSV198 MTG motif gene family protein [... 32 5.0
gi|2736153 (AF021936) myotonic dystrophy kinase-related Cdc42-bi... 32 5.0
gi|4506751|oth|NP_002947|PRSN restin (Reed-Steinberg cell-expres... 32 5.0
gi|3660672 (AF055895) nonmuscle myosin II heavy chain A [Xenopus... 32 5.0
gi|420071|pir||A43336 microtubule-vesicle linker CLIP-170 - huma... 32 5.0
gi|3851586 (AF092564) chromosome-associated protein-C [Homo sapi... 32 5.0
gi|1041785 (U36927) rhoptry protein [Plasmodium yoelii] 32 6.5
gi|2498458|sp|P75471|HMW2_MYCPN CYTADHERENCE HIGH MOLECULAR WEIG... 32 6.5
gi|2687959 (AE001120) B. burgdorferi predicted coding region BB0... 32 6.5
gi|2136310|pir||A57041 transcription regulator Staf-50 - human >... 31 8.5
gi|3764008|emb|CAA15601| (AL008970) predicted using hexExon; MAL... 31 8.5
gi|2982915 (AE000677) putative protein [Aquifex aeolicus] 31 8.5
>gi|1575575 (U66887) RAD50 [Mus musculus]
Length = 1312
Score = 97.9 bits (240), Expect = 8e-20
Identities = 54/176 (30%), Positives = 99/176 (55%), Gaps = 7/176 (3%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
S+ +QK+ + KTLE ++++ + + S+S K +ID+ + + +SK ++ N+I C
Sbjct: 99 SMLCSQKNKKTEFKTLEGVITRMKHGEKVSLSSKCAEIDREMISCLGVSKSVLNNVIFCH 158
Query: 587 QEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTK-------QQDLKLIKQEIE 429
QEDS W L+E +K++ D+IF++T+YIKALD L+++++T+ Q +LK +KQ E
Sbjct: 159 QEDSNWPLSEGKALKQKFDEIFSATRYIKALDTLRQVRQTQGQKVKECQTELKYLKQNKE 218
Query: 428 FXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQN 249
+ + ++ Y +E L +++ E E ++ EI LE
Sbjct: 219 KACEIRDQITSKEAQLASSQEIVRSYEDELEPLKNRLKEIEHNLSKIMKLDNEIKALESR 278
Query: 248 KNQ 240
K Q
Sbjct: 279 KKQ 281
>gi|2687853|emb|CAA99729| (Z75311) RAD50 homologue hsRAD50 [Homo sapiens]
Length = 1318
Score = 96.0 bits (235), Expect = 3e-19
Identities = 53/176 (30%), Positives = 99/176 (56%), Gaps = 7/176 (3%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
S+ TQKS + KTLE ++++ + + S+S K +ID+ + + +SK ++ N+I C
Sbjct: 105 SMVCTQKSKKTEFKTLEGVITRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCH 164
Query: 587 QEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTK-------QQDLKLIKQEIE 429
QEDS W L+E +K++ D+IF++T+YIKAL+ L+++++T+ Q +LK +KQ E
Sbjct: 165 QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVEEYQMELKYLKQYKE 224
Query: 428 FXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQN 249
+ + ++ Y ++ L +++ E E ++ EI L+
Sbjct: 225 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSR 284
Query: 248 KNQ 240
K Q
Sbjct: 285 KKQ 287
>gi|1518806 (U63139) Rad50 [Homo sapiens]
Length = 1312
Score = 96.0 bits (235), Expect = 3e-19
Identities = 53/176 (30%), Positives = 99/176 (56%), Gaps = 7/176 (3%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
S+ TQKS + KTLE ++++ + + S+S K +ID+ + + +SK ++ N+I C
Sbjct: 99 SMVCTQKSKKTEFKTLEGVITRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCH 158
Query: 587 QEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTK-------QQDLKLIKQEIE 429
QEDS W L+E +K++ D+IF++T+YIKAL+ L+++++T+ Q +LK +KQ E
Sbjct: 159 QEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKE 218
Query: 428 FXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQN 249
+ + ++ Y ++ L +++ E E ++ EI L+
Sbjct: 219 KACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDSR 278
Query: 248 KNQ 240
K Q
Sbjct: 279 KKQ 281
>gi|4263721|gb|AAD15407| (AC006223) putative DNA repair protein RAD50 [Arabidopsis thaliana]
Length = 1292
Score = 92.1 bits (225), Expect = 4e-18
Identities = 49/171 (28%), Positives = 94/171 (54%), Gaps = 2/171 (1%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESI--SGKIGDIDKSVEAITNISKPLIENIIL 594
S QLTQK++ + K +E++L E + S + D+D+ + A+ +SK ++EN+I
Sbjct: 98 SFQLTQKASKMEYKAIESVLQTINPHTGEKVCLSYRCADMDREIPALMGVSKAILENVIF 157
Query: 593 CSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXX 414
Q++S W L +P +KK+ DDIF++T+Y KAL+ +K+L K + Q++K K ++E
Sbjct: 158 VHQDESNWPLQDPSTLKKKFDDIFSATRYTKALEVIKKLHKDQAQEIKTFKLKLENLQTL 217
Query: 413 XXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLE 255
+++ + EL + + + EV+N + +K++ L+
Sbjct: 218 KDAAYKLRESIAQDQERTESSKVQMLELETSVQKVDAEVHNKEMMLKDLRKLQ 270
>gi|131782|sp|P12753|RA50_YEAST DNA REPAIR PROTEIN RAD50 (153 KD PROTEIN) >gi|73260|pir||BWBYDL
RAD50 protein - yeast (Saccharomyces cerevisiae)
>gi|4273|emb|CAA32919| (X14814) 153 kD protein (AA 1 -
1312) [Saccharomyces cerevisiae]
>gi|1255968|emb|CAA65494| (X96722) ORF N0872
[Saccharomyces cerevisiae] >gi|1302293|emb|CAA96157|
(Z71526) ORF YNL250w [Saccharomyces cerevisiae]
Length = 1312
Score = 91.3 bits (223), Expect = 7e-18
Identities = 52/152 (34%), Positives = 78/152 (51%), Gaps = 1/152 (0%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYES-ISGKIGDIDKSVEAITNISKPLIENIILC 591
++QL K T KTLE L N S +S + ++D V + K ++E +I C
Sbjct: 97 NIQLLMKKTTTTFKTLEGQLVAINNSGDRSTLSTRSLELDAQVPLYLGVPKAILEYVIFC 156
Query: 590 SQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXX 411
QEDS W L+EP +KK+ D+IF + K+ KALD LK +KK D+KL+KQ +E
Sbjct: 157 HQEDSLWPLSEPSNLKKKFDEIFQAMKFTKALDNLKSIKKDMSVDIKLLKQSVEHLKLDK 216
Query: 410 XXXXXXVTEYKNIEKKQNVYNGFVEELTHKILE 312
++ K + YN V E+ ++ E
Sbjct: 217 DRSKAMKLNIHQLQTKIDQYNEEVSEIESQLNE 249
>gi|2687855|emb|CAA99730| (Z75312) RAD50 homologue ceRAD50 [Caenorhabditis elegans]
>gi|4008379|emb|CAB01581| (Z78200) Similarity to Yeast
DNA repair protein RAD50 (SW:RA50_YEAST); cDNA EST
EMBL:D32987 comes from this gene; cDNA EST EMBL:D34349
comes from this gene; cDNA EST EMBL:D35707 comes from
this gene; cDNA EST EMBL:D37392 comes ...
Length = 1298
Score = 65.2 bits (156), Expect = 5e-10
Identities = 32/139 (23%), Positives = 69/139 (49%)
Query: 680 SISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLDDIFNSTKYIK 501
++S K+ D + ++ + + + + +I C QEDS W L+EP +KKR DDIF TK++K
Sbjct: 127 TLSSKVCDFNTALLKHLGVPRAVFKYVIFCHQEDSTWPLSEPKELKKRFDDIFQLTKFVK 186
Query: 500 ALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHK 321
A +++K++ +++++ + + + E+K + +EL +
Sbjct: 187 AQERMKKIVLDFKKEMQTHEMSKQLYETHVRDKLVARQNQEECERKISKRKEETDELKER 246
Query: 320 ILEKEKEVNNFTLKIKEID 264
+K++ I E++
Sbjct: 247 KANGQKKIEEMRTSIHELE 265
>gi|4493978|emb|CAB39037| (AL034559) predicted using hexExon; MAL3P7.21 (PFC0960c),
Hypothetical protein, len: 1929 aa [Plasmodium
falciparum]
Length = 1928
Score = 39.1 bits (89), Expect = 0.038
Identities = 40/164 (24%), Positives = 84/164 (50%), Gaps = 24/164 (14%)
Query: 764 LQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQ 585
++ +K+ TQ+ ++LE+ + Y + + ++ + ++ + N+++ + N
Sbjct: 1562 IEREKKNFTQKVESLEHAFKQ----SYNQLKDQNENLQQQIKQLKNVNQDIKTNSKNLKN 1617
Query: 584 EDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELK---KTKQQDLKL-----IKQEIE 429
+ +IK+ + K+IK L +K+ K + Q LK+ IK++++
Sbjct: 1618 VNEI-------LIKETKNYSQQKEKFIKGLKNIKQAYIKLKNENQQLKINAFEYIKKDVQ 1670
Query: 428 FXXXXXXXXXXXVTEYKN-----------IEKKQNVYNGF---VEELTHKI--LEKEKEV 297
+ E K +++KQN+ N +E++ HKI + KEKE
Sbjct: 1671 DNYVTLNVHNNILNEQKKLFVQIDILKSQVDQKQNIINNMKEQIEDVNHKIASINKEKEE 1730
Query: 296 NNFTLKIK 273
N T+KIK
Sbjct: 1731 LNTTIKIK 1738
Score = 36.4 bits (82), Expect = 0.25
Identities = 33/175 (18%), Positives = 82/175 (46%), Gaps = 11/175 (6%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
++ + +++ ++ +E + ++++K++ I+ + ++ +E + K + +
Sbjct: 1285 NIHIEKETEIKKTNDIEKEKNTKLSNKFDIINKENNNLHNKIETLLKNEKEISTENVKLI 1344
Query: 587 QEDSAWYLAEPGVI---------KKRLDDIFN--STKYIKALDKLKELKKTKQQDLKLIK 441
+ + Y+ + K+++ + +N + ++IK +++L+ K+ K++ +K I
Sbjct: 1345 ETNKTLYIENEKLSNDLKNTLKEKEKIQENYNKINKEHIKIIEELQSYKEIKEKHMKEIT 1404
Query: 440 QEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDV 261
Q E K+I + Q N F E + E EK N K KE+
Sbjct: 1405 QIKEQIHNLD----------KHIAQIQIEKNNFEESYLKEKNENEKMSNILEEKYKELST 1454
Query: 260 LEQNKN 243
E +KN
Sbjct: 1455 YEIDKN 1460
>gi|4049717 (AF063866) ORF MSV156 hypothetical protein [Melanoplus sanguinipes
entomopoxvirus]
Length = 1127
Score = 39.1 bits (89), Expect = 0.038
Identities = 39/152 (25%), Positives = 69/152 (44%), Gaps = 6/152 (3%)
Query: 698 VNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLD---- 531
+ + E+IS KI D+++ + + + SK L++ I Q+ A +K +
Sbjct: 664 ITNNIENISNKIKDLNEFIISNEDSSKELLDEIRKYKQQFDKIKDAMNTEVKSFENTLQK 723
Query: 530 DIFNSTKYIKALDKLKELKKTKQQDL--KLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQN 357
DI + I L ++ TK DL KL EF T KN ++K
Sbjct: 724 DIDSIKSNINELTNAYDIINTKANDLDDKLNNYGSEFKNLYNNASDLLDTIQKNNDEKVK 783
Query: 356 VYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKN 243
N ++E+ ++ +E VNNF ++ + + E NK+
Sbjct: 784 QLNEYLEKNKNQSIEINDIVNNFIKELIKFNNTETNKS 821
>gi|3845107 (AE001375) hypothetical protein [Plasmodium falciparum]
Length = 1979
Score = 37.1 bits (84), Expect = 0.15
Identities = 40/166 (24%), Positives = 77/166 (46%), Gaps = 11/166 (6%)
Query: 734 QQKTLENLLSKRVND------KYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSA 573
Q K L+N K N + +++ ++ +K ++ I N+SK I +I E
Sbjct: 397 QLKDLKNSFVKNNNQLKVYKCEIKNLKTELEKKEKELKDIENVSKEEINKLINQLNEKEK 456
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXX 393
LA K ++I + +K K+ +++ + Q++ IKQ
Sbjct: 457 QILA---FNKNHKEEIHGLKEELKESVKITKIETQELQEMVDIKQ--------------- 498
Query: 392 VTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNF-TLKIKEI----DVLEQNKNQY 237
K +++ Q YN +E ++ ++ +KEKE N + I+EI + LE+ +Y
Sbjct: 499 ----KELDQLQEKYNAQIESISIELSKKEKEYNQYKNTYIEEINNLNEKLEETNKEY 551
Score = 32.8 bits (73), Expect = 2.9
Identities = 39/160 (24%), Positives = 68/160 (42%), Gaps = 3/160 (1%)
Query: 749 KSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAW 570
K+ + LEN L + S+S KI + + +E + K + + I D
Sbjct: 121 KNIIHKDNELENQLKDTLKS-ISSLSNKIVNYESKIEELEKELKEVKDKNI--DNNDYEN 177
Query: 569 YLAEPGVIKKRLDDIFNSTKYI---KALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXX 399
L E K+ D+ N + + K LD K KK +++ +IK+E F
Sbjct: 178 KLKEKEDFVKQKIDMLNEKENLLQEKELDINKREKKINEKEKNIIKKEETFH-------- 229
Query: 398 XXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKE 270
NIEK+ N E ++ +I++ +K + ++IKE
Sbjct: 230 -------NIEKEYLEKNKERETISIEIIDIKKHLEKLKIEIKE 265
>gi|2129174|pir||A64505 P115 homolog - Methanococcus jannaschii
Length = 1169
Score = 36.4 bits (82), Expect = 0.25
Identities = 36/138 (26%), Positives = 58/138 (41%)
Query: 662 GDIDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLK 483
GD+ K + + +I+ I ++ D AE + K R + + + LK
Sbjct: 148 GDLLKIINISPIERRKIIDEISGIAEFDEKKKKAEEELKKARELIEMIDIRISEVENNLK 207
Query: 482 ELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEK 303
+LKK K+ K IK E +Y I KK + N +E + + I E+
Sbjct: 208 KLKKEKEDAEKYIKLNEELKAA----------KYALILKKVSYLNVLLENIQNDIKNLEE 257
Query: 302 EVNNFTLKIKEIDVLEQN 249
N F K++EIDV +N
Sbjct: 258 LKNEFLSKVREIDVEIEN 275
>gi|2826443 (U67604) chromosome segretation protein (smc1) [Methanococcus
jannaschii]
Length = 1169
Score = 36.4 bits (82), Expect = 0.25
Identities = 36/138 (26%), Positives = 58/138 (41%)
Query: 662 GDIDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLK 483
GD+ K + + +I+ I ++ D AE + K R + + + LK
Sbjct: 148 GDLLKIINISPIERRKIIDEISGIAEFDEKKKKAEEELKKARELIEMIDIRISEVENNLK 207
Query: 482 ELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEK 303
+LKK K+ K IK E +Y I KK + N +E + + I E+
Sbjct: 208 KLKKEKEDAEKYIKLNEELKAA----------KYALILKKVSYLNVLLENIQNDIKNLEE 257
Query: 302 EVNNFTLKIKEIDVLEQN 249
N F K++EIDV +N
Sbjct: 258 LKNEFLSKVREIDVEIEN 275
>gi|729230|sp|P41004|CUT3_SCHPO CHROMOSOME SEGREGATION PROTEIN CUT3 >gi|1076872|pir||S51622 cut3
protein - fission yeast (Schizosaccharomyces pombe)
>gi|603501|dbj|BAA06454| (D30788) cut3 protein
[Schizosaccharomyces pombe]
Length = 1324
Score = 35.6 bits (80), Expect = 0.44
Identities = 31/143 (21%), Positives = 61/143 (41%), Gaps = 1/143 (0%)
Query: 695 NDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLDDIFNS 516
N++ ++ KI ++DK VEAI ++ L+ I + + K ++DD+
Sbjct: 888 NERKRNLQNKISNMDKEVEAININNEGLVTEIKTLQDKIMEIGGIRYRIQKSKVDDLHEQ 947
Query: 515 TKYIK-ALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFV 339
K++K L+K+ KK +Q + + E+ + K + N Y V
Sbjct: 948 LKFVKDKLNKMSFKKKKNEQRSQSFQVELSNLTSEYDTTTESIATLKTELQSLNKY---V 1004
Query: 338 EELTHKILEKEKEVNNFTLKIKEI 267
+E ++ E E + + I E+
Sbjct: 1005 DEHKSRLREFENALWDINSSIDEL 1028
>gi|1151158 (U43145) repeat organellar protein [Plasmodium chabaudi]
Length = 1939
Score = 35.6 bits (80), Expect = 0.44
Identities = 54/220 (24%), Positives = 93/220 (41%), Gaps = 19/220 (8%)
Query: 665 IGDIDKSVEAITNISKPLIENIILCSQED---SAWYLAEPGVIKKRLDDIFNSTKYIKAL 495
+ +++K ++ N+ + +N ++ +E+ SA L E + ++ +++ NS I+ L
Sbjct: 1041 VNEVEKKNASLLNMLEENHKNEMIKLKEEHKESASDLVEK--LYQKDEEVKNSNNKIEEL 1098
Query: 494 DK-LKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEY-KNIEKKQNVYNGFVEELTHK 321
+K+L + K I +E+E EY + I K + V N + K
Sbjct: 1099 TNVIKDLNDSIMCYKKQILEEVE-----------KRNEYNEEINKLKIVQNEMKDMNDKK 1147
Query: 320 ILEKEKEVNNFTLKIKEIDVLEQNKNQYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXK 141
ILEKE E+ K+ V E +N Y K
Sbjct: 1148 ILEKENEIKKLNKKLSNYKVFETKENTYKNSEMVVNENKERIIVDSVCKENISESDVEGK 1207
Query: 140 FVEVKIEELSSAKENNLKKIS-NTNE-------------NVIELFEKEVIIETKNITSL 6
+K+ KE N+ I+ N NE N IE+++KE+ KNI L
Sbjct: 1208 GGNLKMTLSLKKKERNIFSINDNKNESSELVDTIKSAYINKIEMYKKEIEDNGKNIEDL 1266
>gi|2952522 (AF051357) golgin-245 [Mus musculus]
Length = 1218
Score = 35.6 bits (80), Expect = 0.44
Identities = 40/168 (23%), Positives = 76/168 (44%), Gaps = 4/168 (2%)
Query: 767 SLQLTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
SL T K+ QQ+ T + L +R+ E K + ++ E + +
Sbjct: 538 SLNETLKNYNQQRDTEHSGLVQRLQHLEELGEEKDNKVREAEETVLRL------------ 585
Query: 587 QEDSAWYLAEPGVIKKRLDDIFNSTKY----IKALDKLKELKKTKQQDLKLIKQEIEFXX 420
+E + AE G +KK L+ + +S K +KAL+ EL+ + +LK ++ E
Sbjct: 586 REHVSSLEAELGTVKKELEHVNSSVKSRDGELKALEDKLELESAAKVELK---RKAEQKI 642
Query: 419 XXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEID 264
E K ++ N + EL+ ++ E+EK+V++ K+K ++
Sbjct: 643 AAIRKQLLSQMEEKTQRYAKDTENR-LSELSAQLKEREKQVHSLEDKLKNLE 693
>gi|2983515 (AE000718) hypothetical protein [Aquifex aeolicus]
Length = 978
Score = 34.4 bits (77), Expect = 0.98
Identities = 37/170 (21%), Positives = 75/170 (43%), Gaps = 4/170 (2%)
Query: 746 SNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITN----ISKPLIENIILCSQED 579
S + K L+ + ++ + + KI + + +E + N + K + EN+ ++
Sbjct: 507 SELKHAKELKEKEEREIDTTLKLYAQKINSLKEEMEKLRNEVEELRKEIPENL-----KE 561
Query: 578 SAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXX 399
L E + K++L+ N KY KAL+ ++ K+ Q L + E+E
Sbjct: 562 RIKKLEELRIEKEKLEHKLN--KYRKALEDRQKQKEEAQAKLHKAQTELELLKEKIREKS 619
Query: 398 XXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQY 237
V E+K + + VE L ++E+N K++EI+ E+ ++
Sbjct: 620 RLVKEFKELYR--------VERLEDYEESLKEEINYINSKLQEIEEKEKKLRKH 665
>gi|2128750|pir||E64456 hypothetical protein MJ1254 - Methanococcus jannaschii >gi|1591888
(U67566) M. jannaschii predicted coding region MJ1254
[Methanococcus jannaschii]
Length = 469
Score = 34.0 bits (76), Expect = 1.3
Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 380 KNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEID--VLEQNKN 243
K IE+ +N+ N L +K+ EKE+E+ N +KIK+++ + + NKN
Sbjct: 277 KIIERTKNIKNELTS-LKNKLKEKEEEIKNLAIKIKDLEDKLSKANKN 323
>gi|285152|pir||S28061 SCP1 protein - rat >gi|57213|emb|CAA48006| (X67805) SCP1 [Rattus
norvegicus]
Length = 946
Score = 33.6 bits (75), Expect = 1.7
Identities = 44/167 (26%), Positives = 86/167 (51%), Gaps = 38/167 (22%)
Query: 749 KSNTQQQKT-LENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSA 573
K+N ++KT L++ K +N+K + ++ ++ DI S++ + K L E++ + ++ +
Sbjct: 245 KANQLEEKTKLQDENLKELNEKKDHLTSELEDIKMSMQRSMSTQKTLEEDLQIATK--TI 302
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKALD---------KLKELKKTKQQ-------DLKLIK 441
+ L E K+ + N K +L L+EL +T+QQ LKLI
Sbjct: 303 YQLTEE---KEAQMEELNKAKTTHSLVVTELKATTCTLEELLRTEQQRLENNEDQLKLIT 359
Query: 440 QEI---------------------EFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTH 324
E+ E + E K +EK G +ELT
Sbjct: 360 MELQKKSSELEEMTKFKNNKEVELEELKTILAEDQKLLDEKKQVEKLAEELQGKEQELTF 419
Query: 323 KILEKEKEVNNFTLKIKEIDVLEQN 249
+ +EKE+++ +++ E++
Sbjct: 420 LLQTREKEIHDLEVQVTVTKTSEEH 444
>gi|2895538 (AF036485) replication protein [Plasmid pNZ4000]
Length = 401
Score = 33.6 bits (75), Expect = 1.7
Identities = 31/91 (34%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 752 QKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIE-NIILCSQEDS 576
QK N++ L LS + N +YE S K G + VEA N S P+ E +I + D
Sbjct: 159 QKLNSKYSLILYRWLSMQYN-QYEHYSVKGGRRAEQVEAYRNPSIPVKELRVITDTVNDY 217
Query: 575 AWYLA-EPGVIKKRLDDIFNSTKYIKALDKLKE 480
+ + E V+KK L++I T + DK+K+
Sbjct: 218 VRFQSLETWVLKKPLEEINAHTSFNVTYDKIKK 250
>gi|3041729|sp|Q03410|SCP1_RAT SYNAPTONEMAL COMPLEX PROTEIN 1 (SCP-1 PROTEIN)
Length = 997
Score = 33.6 bits (75), Expect = 1.7
Identities = 44/167 (26%), Positives = 86/167 (51%), Gaps = 38/167 (22%)
Query: 749 KSNTQQQKT-LENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSA 573
K+N ++KT L++ K +N+K + ++ ++ DI S++ + K L E++ + ++ +
Sbjct: 296 KANQLEEKTKLQDENLKELNEKKDHLTSELEDIKMSMQRSMSTQKTLEEDLQIATK--TI 353
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKALD---------KLKELKKTKQQ-------DLKLIK 441
+ L E K+ + N K +L L+EL +T+QQ LKLI
Sbjct: 354 YQLTEE---KEAQMEELNKAKTTHSLVVTELKATTCTLEELLRTEQQRLENNEDQLKLIT 410
Query: 440 QEI---------------------EFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTH 324
E+ E + E K +EK G +ELT
Sbjct: 411 MELQKKSSELEEMTKFKNNKEVELEELKTILAEDQKLLDEKKQVEKLAEELQGKEQELTF 470
Query: 323 KILEKEKEVNNFTLKIKEIDVLEQN 249
+ +EKE+++ +++ E++
Sbjct: 471 LLQTREKEIHDLEVQVTVTKTSEEH 495
>gi|4092846|dbj|BAA73535| (AB019987) chromosome-associated polypeptide-C [Homo sapiens]
Length = 1288
Score = 33.6 bits (75), Expect = 1.7
Identities = 45/163 (27%), Positives = 76/163 (46%), Gaps = 6/163 (3%)
Query: 740 TQQQKTLENLLSKRVNDKYESISGKIG----DIDKSVEAITNISKPLIENIILCSQEDSA 573
TQ++K E+ +K +N+K +S ++ D+ + + + I+K + EN +Q D
Sbjct: 339 TQKEKIHED--TKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLD-- 394
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXX 393
L+D+ K A K K+L+K Q+D K+++E
Sbjct: 395 ------------LEDVQVREKLKHATSKAKKLEKQLQKD----KEKVE------------ 426
Query: 392 VTEYKNIEKKQNVYNGFVEELT--HKILEKEKEVNNFTLKIKEIDVLEQ 252
E+K+I K N + E T + LEKEKE LK + +D L+Q
Sbjct: 427 --EFKSIPAKS---NNIINETTTRNNALEKEKEKEEKKLK-EVMDSLKQ 469
>gi|2498896|sp|Q60563|SCP1_MESAU SYNAPTONEMAL COMPLEX PROTEIN 1 (SCP1 PROTEIN) (MEIOTIC CHROMOSOME
SYNAPTIC PROTEIN) >gi|2137097|pir||I48176 synaptonemal
complex protein - golden hamster (fragment) >gi|598125
(L32978) synaptonemal complex protein [Mesocricetus
auratus]
Length = 845
Score = 33.2 bits (74), Expect = 2.2
Identities = 44/167 (26%), Positives = 81/167 (48%), Gaps = 35/167 (20%)
Query: 749 KSNTQQQKT-LENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSA 573
K N + KT L++ K +N K + ++ ++ D S++ N K L E++ + ++ +
Sbjct: 148 KVNQLEDKTKLQDENVKELNKKKDHLTSELEDTKMSLQRSMNTQKALEEDLQIATK--TI 205
Query: 572 WYLAEPGVI------KKRLDDIFNSTKYIKALDKLKELKKTKQQ-------DLKLIKQEI 432
+ L E K + D F T+ L+EL +T+QQ LK++ E+
Sbjct: 206 YQLTEEKEAQMEEFNKAKTDHSFMVTELKATTCTLEELLRTEQQRLVKNEDQLKILTMEL 265
Query: 431 ---------------------EFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKIL 315
E + E K +EK G +ELT +
Sbjct: 266 QKKSNELDEMTKFKNNNEVKLEELKKILAEDQKLLDEKKQVEKLAEELQGKEQELTLLLQ 325
Query: 314 EKEKEVNNFTLKIKEIDVLEQN 249
+EKEV++ ++ + +QN
Sbjct: 326 TREKEVHDLEEQLLVTKISDQN 347
>gi|2496852|sp|Q11102|YL17_CAEEL HYPOTHETICAL 131.5 KD PROTEIN C02F12.7 IN CHROMOSOME X >gi|1109896
(U41545) coded for by C. elegans cDNA yk4b2.5; coded for
by C. elegans cDNA CEESN67F; coded for by C. elegans cDNA
yk94h12.5; coded for by C. elegans cDNA CEESD93F; coded
for by C. elegans cDNA CEESG57F; coded for by C. elegans
cDNA yk4b2.3;...
Length = 1130
Score = 33.2 bits (74), Expect = 2.2
Identities = 42/229 (18%), Positives = 90/229 (38%), Gaps = 7/229 (3%)
Query: 737 QQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENI----ILCSQEDSAW 570
QQ ++ E+ + K + K + + + + +E + K + I + + +
Sbjct: 483 QQAESREHAMKKEFSCKLNELEEQYTSLKEELEESARLDKDELREASEIEIQALRTEKSI 542
Query: 569 YLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXV 390
AE V+ ++++D D ++L K + +L + E+ +
Sbjct: 543 LAAEIRVLTQKIEDEEQD-------DITEQLAKIVEDTSQLTRTLEEYRERITGKDAEIL 595
Query: 389 TEYKNIEKK---QNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQYXXXXXX 219
K +EK+ N + E T K LE KE + T+++ E ++ +Q K+ +
Sbjct: 596 NLRKQLEKEISHTEDRNRLLHENTQKELEAHKETHTETVRVLEAEI-DQFKSAFENEQEY 654
Query: 218 XXXXXXXXXXXXXXXXXXXXXXXXXKFVEVKIEELSSAKENNLKKISNTNENVIEL 51
K V +E +S K+N L+++ + N+N+ L
Sbjct: 655 GKEKSAKIRELEAQNKTLLSEMEKVKHVAENLEAFTSDKDNLLEELESKNKNIEHL 710
>gi|4503469|oth|NP_003557|PEEA1 early endosome-associated protein >gi|2135066|pir||A57013
endosome-associated protein - human >gi|1016368 (L40157)
endosome-associated protein [Homo sapiens]
Length = 1410
Score = 32.8 bits (73), Expect = 2.9
Identities = 28/109 (25%), Positives = 55/109 (49%), Gaps = 3/109 (2%)
Query: 566 LAEPGVIKKRLD-DIFNSTKYIKA--LDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXX 396
LAE IK R + +I + +K+ L+ +KE+ K LI+Q++E
Sbjct: 1126 LAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAA 1185
Query: 395 XVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQ 240
E +N + ++ EEL + +EKE ++++ +K KE+ + + +N+
Sbjct: 1186 VEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS-EIKEKEVGMKKHEENE 1236
>gi|3256959|dbj|BAA29642| (AP000002) 399aa long hypothetical protein [Pyrococcus horikoshii]
Length = 399
Score = 32.8 bits (73), Expect = 2.9
Identities = 40/154 (25%), Positives = 75/154 (47%), Gaps = 15/154 (9%)
Query: 761 QLTQKSNTQQQKTLENLLSKRVND-------KYESISGKIGDIDKSVEAITNISKPLIEN 603
+L K +T K L+ ++ KRV D KYE IS ++ ++ K + +++ L+E
Sbjct: 33 KLMAKKDTLTPKQLDEII-KRVLDAYGSQAAKYEQISKRVDELGKKLGELSSQLSRLVEA 91
Query: 602 IILCSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKAL--DKLKELKKTKQQDLKLIKQEIE 429
+ ++ A + + I ++ ++ + I+ L +K KE K + ++ I +++E
Sbjct: 92 L---EEKKFAVHEKKAESIAEKAAEVTEKVERIEELLEEKPKEEKSELAKKVEEIHKKVE 148
Query: 428 FXXXXXXXXXXXVTEYK------NIEKKQNVYNGFVEELTHKILEKEKE 300
T+ K IEK + V V EL K+ E E E
Sbjct: 149 ELEEKLTGEKLEETKKKVEELEEKIEKGEEVTAEEVGELAEKVEELEAE 197
>gi|2983243 (AE000699) chromosome assembly protein homolog [Aquifex aeolicus]
Length = 1156
Score = 32.8 bits (73), Expect = 2.9
Identities = 26/91 (28%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 536 LDDIFNSTKYIKA----LDKLKELKKTKQQ-DLKLIKQEIEFXXXXXXXXXXXVTEYKNI 372
L++I N K +K L+K KEL++ K++ + K++ +E E + E + I
Sbjct: 197 LEEISNQLKRLKEEKEKLEKFKELQRIKRETEAKILLKEKE----------KLLKERERI 246
Query: 371 EKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEID 264
+ + +E++T +I E EKE+N +KE++
Sbjct: 247 LNELSSLRESLEDITFQIQENEKELNERERLLKEVN 282
>gi|4493894|emb|CAB39003| (AL034558) predicted using hexExon; MAL3P2.16 (PF0235w), Hypothetical
protein, len: 1214 aa [Plasmodium falciparum]
Length = 1213
Score = 32.8 bits (73), Expect = 2.9
Identities = 26/127 (20%), Positives = 63/127 (49%), Gaps = 12/127 (9%)
Query: 656 IDKSVEAITNISKPLIENIILCSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALD----K 489
+++++ +I K ++ Q D +++ + ++ + T+ + D +
Sbjct: 761 VEENILFCFSIDKDKNRLLVCIKQNDDNFFVIPNCIFDEKFPGLQKKTESMIIQDIHEKE 820
Query: 488 LKELKKTKQQDLKLIKQEIE--------FXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEE 333
+ ELK + +L ++K+E E + YKNIE+K+N ++E
Sbjct: 821 ILELKNKQMNELYILKKEKEDIYKEYEEYKKKVTSLINETNYNYKNIEEKENE----IKE 876
Query: 332 LTHKILEKEKEVNNFTLKI 276
L + + + ++E+NN+ +I
Sbjct: 877 LNNTLNKYKEEMNNYKEEI 895
Score = 31.3 bits (69), Expect = 8.5
Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 16/160 (10%)
Query: 719 ENLLSKRVNDKYESISGKIGDIDKSVEAI---------------TNISKPLIENIILCSQ 585
EN+L ND + +I D+ ++E + N K L E I C
Sbjct: 535 ENILPLHTNDDVTKLLDEINDLKNTIENMKKEKINLLSKFKAYTLNNKKELEELKIKCKN 594
Query: 584 EDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXX 405
++ + E ++ + D+I N I+ D KK + +KL +E E
Sbjct: 595 KEEQIKMYE-NKLQNKEDEIMNYVNEIQNKD-----KKIESYHIKLHNKEEEI------- 641
Query: 404 XXXXVTEYKN-IEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQ 240
Y N I+ K+ +V EL + ++KEK+ ++K I+ + +N N+
Sbjct: 642 -----MNYVNEIQNKEEEIIKYVNELQNSDVQKEKK------ELKTINEVLKNTNE 686
>gi|631129|pir||S44243 endosomal protein - human >gi|475934|emb|CAA55632| (X78998) endosomal
protein [Homo sapiens]
Length = 1411
Score = 32.8 bits (73), Expect = 2.9
Identities = 28/109 (25%), Positives = 55/109 (49%), Gaps = 3/109 (2%)
Query: 566 LAEPGVIKKRLD-DIFNSTKYIKA--LDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXX 396
LAE IK R + +I + +K+ L+ +KE+ K LI+Q++E
Sbjct: 1126 LAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAA 1185
Query: 395 XVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQ 240
E +N + ++ EEL + +EKE ++++ +K KE+ + + +N+
Sbjct: 1186 VEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS-EIKEKEVGMKKHEENE 1236
>gi|3876121|emb|CAA92298| (Z68161) cDNA EST EMBL:C13248 comes from this gene [Caenorhabditis
elegans]
Length = 644
Score = 32.5 bits (72), Expect = 3.8
Identities = 36/158 (22%), Positives = 73/158 (45%), Gaps = 3/158 (1%)
Query: 737 QQQKTLENLLSKR--VND-KYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAWY 567
+Q+K ++ LL K +ND Y I + IDK + + K I +I ED+
Sbjct: 154 KQEKLMDQLLDKLKVLNDGDYYDIFHLLETIDKIIVTFSLYFKDPI--LITKKMEDNKQ- 210
Query: 566 LAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVT 387
+I+K D++ TK +++L+ + + + +D L+ +EF
Sbjct: 211 -----IIQKLEDEVDYLTKNLESLNPSQLVTSLENKDDYLLVT-VEFQKRKNILFSELKK 264
Query: 386 EYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEID 264
+ + I+ Q +N + ++ K++EK E+ + L + +D
Sbjct: 265 KNEEIKMLQESFNVYQKDSIEKVMEKFLELQHQNLTVFSVD 305
>gi|2128791|pir||A64465 hypothetical protein MJ1322 - Methanococcus jannaschii >gi|1591962
(U67572) purine NTPase [Methanococcus jannaschii]
Length = 1005
Score = 32.5 bits (72), Expect = 3.8
Identities = 42/172 (24%), Positives = 71/172 (40%), Gaps = 3/172 (1%)
Query: 752 QKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSA 573
+K+ + + LL + N ESI + +I++ + + N+ K IE
Sbjct: 425 EKNINDLETRINKLLEETKNIDIESIENSLKEIEEKKKVLENLQKEKIE----------- 473
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKA-LDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXX 396
+ K+L +I + K +K LD+LKE+ + L K I+
Sbjct: 474 --------LNKKLGEINSEIKRLKKILDELKEV----EGKCPLCKTPID---------EN 512
Query: 395 XVTEYKNIEKKQ--NVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQNKNQY 237
E N K Q N Y +EE+ KI E EK++ +I + + L+ K Y
Sbjct: 513 KKMELINQHKTQLNNKYTE-LEEINKKIREIEKDIEKLKKEIDKEENLKTLKTLY 566
>gi|2224697|dbj|BAA20832| (AB002376) KIAA0378 [Homo sapiens]
Length = 808
Score = 32.1 bits (71), Expect = 5.0
Identities = 37/167 (22%), Positives = 77/167 (45%), Gaps = 11/167 (6%)
Query: 749 KSNTQQQKT----LENLLSKRVND------KYESISGKIGDIDKSVEAITNISKPLIENI 600
KS+++ KT L+ LSK+ ++ K E++S + D + +E +++
Sbjct: 277 KSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIE--------VLKES 328
Query: 599 ILCSQEDSAWYLAEPGVIKKRLDDIFNS-TKYIKALDKLKELKKTKQQDLKLIKQEIEFX 423
+ ++ +A E ++ RL++ + K K L L E K T +++ +K +E
Sbjct: 329 LTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVK 388
Query: 422 XXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLEQN 249
E+K NV +E L ++ +K+K++ N ++K + N
Sbjct: 389 -----------------ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN 429
>gi|2649562 (AE001032) purine NTPase, putative [Archaeoglobus fulgidus]
Length = 886
Score = 32.1 bits (71), Expect = 5.0
Identities = 37/168 (22%), Positives = 86/168 (51%), Gaps = 21/168 (12%)
Query: 758 LTQKSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENII----LC 591
L+Q+ ++QK + +R++++ +SI + + V + + K L E+ L
Sbjct: 179 LSQEEQIKRQKEEKKAEIERISEEIKSIESLREKLSEEVRNLESRLKELEEHKSRLESLR 238
Query: 590 SQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXX 411
QE S L E ++++L ++ K + ++++++L+K K +++K +K + E
Sbjct: 239 KQESSV--LQEVRGLEEKLRELEKQLKEV--VERIEDLEK-KAKEVKELKPKAERYSILE 293
Query: 410 XXXXXXVTEYKNIEKKQNVY-----------------NGFVEELTHKILEKEKEVNNFTL 282
+++EK++ N +EE+T +I E E+E+ F
Sbjct: 294 KLLSEINQALRDVEKREGDLTREAAGIQAQLKKAEEDNSKLEEITKRIEELERELERFEK 353
Query: 281 KIKEIDVLE 255
+ ++ L+
Sbjct: 354 SHRLLETLK 362
>gi|4249701 (AF097907) myosin heavy chain [Rana catesbeiana]
Length = 826
Score = 32.1 bits (71), Expect = 5.0
Identities = 46/164 (28%), Positives = 77/164 (46%), Gaps = 12/164 (7%)
Query: 764 LQLTQKSNTQ---QQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIIL 594
LQL NT +K LE+ +++ N+ ES+ DK+ +AIT+ + E L
Sbjct: 604 LQLLHSQNTSLLNSKKKLESDIAQLTNEVEESVQESRNAEDKAKKAITDAALMAEE---L 660
Query: 593 CSQEDSAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKEL--KKTKQQDLKLIKQEIEFXX 420
++D++ +L +KK L+ ++ LD+ ++L K K+Q KL + E
Sbjct: 661 KKEQDTSAHLER---MKKNLEQSVKDLQH--RLDEAEQLAMKGGKKQLQKLEVRVRELES 715
Query: 419 XXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHKILEKEKE-------VNNFTLKIK 273
V K + K Y V+ELT++ E K V+ LK+K
Sbjct: 716 ELDNEQKRGVESIKGVRK----YERRVKELTYQTEEDRKNLLRLQDLVDKLQLKVK 767
>gi|4049801 (AF063866) ORF MSV198 MTG motif gene family protein [Melanoplus
sanguinipes entomopoxvirus]
Length = 399
Score = 32.1 bits (71), Expect = 5.0
Identities = 37/143 (25%), Positives = 62/143 (42%), Gaps = 11/143 (7%)
Query: 749 KSNTQQQKTLENLLSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAW 570
++NT ++ E +L+ N+K K DI + E N K IENI C+ E S W
Sbjct: 59 RNNTNLKRDFEKILN---NNKINYKKIKYNDIINN-EDYYNKVKEEIENIRPCNLEKSTW 114
Query: 569 YLAEPGVIKKRLDDIFNST-----KYIKALDKL------KELKKTKQQDLKLIKQEIEFX 423
++ K + + + +Y L+K+ K ++ +K IKQ+ E
Sbjct: 115 FILSVDEFKMLIMRLSTNVAIEVREYFILLEKILFKYSNYTNKYLIEESIKQIKQKDE-- 172
Query: 422 XXXXXXXXXXVTEYKNIEKKQNVYNGFVEELTHK 321
+ K ++ NV N FV + K
Sbjct: 173 ------------QLKILQSSNNVLNNFVNNIKQK 194
>gi|2736153 (AF021936) myotonic dystrophy kinase-related Cdc42-binding kinase
MRCK-beta [Rattus norvegicus]
Length = 1702
Score = 32.1 bits (71), Expect = 5.0
Identities = 19/84 (22%), Positives = 39/84 (45%)
Query: 521 NSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGF 342
N K IK L++ E K+K D +++++E K +EK+ +
Sbjct: 482 NRDKEIKRLNEELERMKSKMADSNRLERQLEDTVTLRQEHEDSTQRLKGLEKQYRLARQE 541
Query: 341 VEELTHKILEKEKEVNNFTLKIKE 270
EEL +++E + + + T ++K+
Sbjct: 542 KEELHKQLVEASERLKSQTKELKD 565
>gi|4506751|oth|NP_002947|PRSN restin (Reed-Steinberg cell-expressed intermediate
filament-associated protein)
>gi|266902|sp|P30622|REST_HUMAN RESTIN (CYTOPLASMIC
LINKER PROTEIN-170 ALPHA-2) (CLIP-170) (REED-STERNBERG
INTERMEDIATE FILAMENT ASSOCIATED PROTEIN)
>gi|88551|pir||S22695 restin - human
>gi|35999|emb|CAA46050| (X64838) restin [Homo sapiens]
Length = 1427
Score = 32.1 bits (71), Expect = 5.0
Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 521 NSTKYIKALDKLKELKKTKQQDLKLIKQEIEF--XXXXXXXXXXXVTEYKNIEKKQNVYN 348
N+ K ++ L+K KEL + Q ++ ++EIE + +N++ + +
Sbjct: 1118 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1177
Query: 347 GFVEELTHKILEKEKEV-NNFTLKIKE 270
E +H+ LE+E+ V NN L++K+
Sbjct: 1178 SRDEVTSHQKLEEERSVLNNQLLEMKK 1204
>gi|3660672 (AF055895) nonmuscle myosin II heavy chain A [Xenopus laevis]
Length = 1964
Score = 32.1 bits (71), Expect = 5.0
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 1/159 (0%)
Query: 734 QQKTLENL-LSKRVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQEDSAWYLAE 558
Q++T + L S ++ + +G + +++ EA N+ K + L SQ
Sbjct: 1318 QEETRQKLSFSTKLKQMEDEKNGLLEQLEEEEEAKKNLCKQIST---LQSQMTD------ 1368
Query: 557 PGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYK 378
+KK++D+ S L+ ++ELKK Q+DL+ + Q E Y
Sbjct: 1369 ---MKKKMDENVGS------LETVEELKKKLQKDLEAVNQRFE----------EKAAAYD 1409
Query: 377 NIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVL 258
+EK + +++++ + + + V+N K K+ D L
Sbjct: 1410 KLEKTKTRLQQELDDISVDLDHQRQIVSNLEKKQKKFDQL 1449
>gi|420071|pir||A43336 microtubule-vesicle linker CLIP-170 - human >gi|180622 (M97501)
cytoplasmic linker protein-170 alpha-2 [Homo sapiens]
Length = 1392
Score = 32.1 bits (71), Expect = 5.0
Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 521 NSTKYIKALDKLKELKKTKQQDLKLIKQEIEF--XXXXXXXXXXXVTEYKNIEKKQNVYN 348
N+ K ++ L+K KEL + Q ++ ++EIE + +N++ + +
Sbjct: 1083 NNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGR 1142
Query: 347 GFVEELTHKILEKEKEV-NNFTLKIKE 270
E +H+ LE+E+ V NN L++K+
Sbjct: 1143 SRDEVTSHQKLEEERSVLNNQLLEMKK 1169
>gi|3851586 (AF092564) chromosome-associated protein-C [Homo sapiens]
Length = 1202
Score = 32.1 bits (71), Expect = 5.0
Identities = 44/163 (26%), Positives = 75/163 (45%), Gaps = 6/163 (3%)
Query: 740 TQQQKTLENLLSKRVNDKYESISGKIG----DIDKSVEAITNISKPLIENIILCSQEDSA 573
TQ++K E+ +K +N+K +S ++ D+ + + + I+K + EN + D
Sbjct: 253 TQKEKIHED--TKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTHVD-- 308
Query: 572 WYLAEPGVIKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXX 393
L+D+ K A K K+L+K Q+D K+++E
Sbjct: 309 ------------LEDVQVREKLKHATSKAKKLEKQLQKD----KEKVE------------ 340
Query: 392 VTEYKNIEKKQNVYNGFVEELT--HKILEKEKEVNNFTLKIKEIDVLEQ 252
E+K+I K N + E T + LEKEKE LK + +D L+Q
Sbjct: 341 --EFKSIPAKS---NNIINETTTRNNALEKEKEKEEKKLK-EVMDSLKQ 383
>gi|1041785 (U36927) rhoptry protein [Plasmodium yoelii]
Length = 2401
Score = 31.7 bits (70), Expect = 6.5
Identities = 41/161 (25%), Positives = 73/161 (44%), Gaps = 7/161 (4%)
Query: 755 TQKSNTQQQKTLENLLSKRVNDKYESISGKI-GDIDKSVEAITNISKPLIENIILCSQED 579
T KS+ + +T N LS+ + D + I G+I +++K++E N K L I ++E+
Sbjct: 349 TVKSHLKNIET-NNKLSETILDIIKYIYGEITNELNKTLEDFKNKEKGLSNKIDEYAKEN 407
Query: 578 SAWYLAEPGV--IKKRLDDIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXXXX 405
+ + + IKK +D N +D +KE K +Q+ K+ ++
Sbjct: 408 VQLNVYKSNILEIKKHYNDQIN-------IDNIKE--KEAKQNYDQFKEHMKTIPPNEMK 458
Query: 404 XXXXVTEYKNIE----KKQNVYNGFVEELTHKILEKEKEVNNFTLKIK 273
E K ++ K N YN F + K+ + + T KIK
Sbjct: 459 YQKPSIEIKIMKDEFLSKVNKYNDFDKVYKEKVESEHNKFTELTNKIK 506
>gi|2498458|sp|P75471|HMW2_MYCPN CYTADHERENCE HIGH MOLECULAR WEIGHT PROTEIN 2 (CYTADHERENCE ACCESSORY
PROTEIN 2) >gi|2146221|pir||S73852 hypothetical protein
F10_orf1818 - Mycoplasma pneumoniae (SGC3) (ATCC 29342)
>gi|1674221 (AE000051) Mycoplasma pneumoniae, F10_orf1818
Protein [Mycoplasma pneumoniae] >gi|1945046 (U59896)
cytadherence accessory [Mycoplasma pneumoniae]
Length = 1818
Score = 31.7 bits (70), Expect = 6.5
Identities = 45/169 (26%), Positives = 72/169 (41%), Gaps = 11/169 (6%)
Query: 761 QLTQKSNTQQQKTLENLLSKRVN--DKYESISGKIGDIDKSVEAITNISKPLIENIILCS 588
QLT N +Q+ + + N + E + K+ D E NISK L E +
Sbjct: 639 QLTAAFNKEQEAVERDWKDRLANLEKQKEMLGDKVHQFD---ENSLNISKKLAERELAIK 695
Query: 587 QEDSAWYLAEPGVIKKRLDDIFNSTKYIKA-LDKLKELKKTKQQDLKLIKQEI-EFXXXX 414
++ A+ K+L N+ +K LDKL E KT++ +L+ K+ I +F
Sbjct: 696 FKEKELEAAQ-----KQLSLDNNNNAGLKLQLDKLSESLKTERLELEASKERILDFYDES 750
Query: 413 XXXXXXXVT-------EYKNIEKKQNVYNGFVEELTHKILEKEKEVNNFTLKIKEIDVLE 255
+ E K +EK Q E LEK + L+I++ +LE
Sbjct: 751 SRRIADYESDLQARLAEVKTLEKNQQETAAKSERELKVALEKLNQAKKAFLQIRKQQLLE 810
>gi|2687959 (AE001120) B. burgdorferi predicted coding region BB0075 [Borrelia
burgdorferi]
Length = 469
Score = 31.7 bits (70), Expect = 6.5
Identities = 46/155 (29%), Positives = 73/155 (46%), Gaps = 19/155 (12%)
Query: 731 QKTLENLLSKRVNDKYESISGKIG---DIDKSVEAIT-----NISKPLIENIILCSQEDS 576
Q +E S +N K E+I K G +DK + IT N K +IE+I + +D
Sbjct: 23 QSNIEYNFSYIINTKKENIDLKKGIEKQLDKIYDKITEHIVNNDDKSIIEDIYI--NQDI 80
Query: 575 AWYLAEPGVIKKRLD-----DIFNSTKYIKALDKLKELKKTKQQDLKLIKQEIEFXXXXX 411
E +KK +D +I + + K+ ELKK Q K+ E+
Sbjct: 81 IKTELEISKLKKEMDKKKLQNIITAKEKHNTKTKIDELKKNIQNINNKQKKFAEY----F 136
Query: 410 XXXXXXVTEYKNIEKKQNVYN----GFVEELTHKI--LEKEKEVNNFTLKIKEI 267
+YK IE++ N+ N F+ E I ++ +K N + L+I I
Sbjct: 137 NNLKKLKVKYKKIEEQTNISNLNKEFFIREELFFINYIDLKKIENYYLLEISNI 190
>gi|2136310|pir||A57041 transcription regulator Staf-50 - human >gi|899300|emb|CAA57684|
(X82200) gpStaf50 [Homo sapiens]
Length = 442
Score = 31.3 bits (69), Expect = 8.5
Identities = 22/92 (23%), Positives = 43/92 (45%), Gaps = 2/92 (2%)
Query: 752 QKSNTQQQKTLENLLSK--RVNDKYESISGKIGDIDKSVEAITNISKPLIENIILCSQED 579
QK + L+NL + ++ + + S I D+ + +T S +++++I +
Sbjct: 199 QKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRR---LTGSSVEMLQDVIDVMKRS 255
Query: 578 SAWYLAEPGVIKKRLDDIFNSTKYIKALDKLKEL 477
+W L +P + K+L +F L LKEL
Sbjct: 256 ESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKEL 289
>gi|3764008|emb|CAA15601| (AL008970) predicted using hexExon; MAL3P4.10 (PFC0515c),
Hypothetical protein, len: 1237 aa [Plasmodium
falciparum]
Length = 1236
Score = 31.3 bits (69), Expect = 8.5
Identities = 12/36 (33%), Positives = 21/36 (58%)
Query: 247 LFCSNTSISFIFNVKLFTSFSFSNILCVNSSTNPLY 354
L N I ++N+ ++T+F F NI+ ++TN Y
Sbjct: 1083 LLIINACIKLVYNLSIYTNFIFKNIIYDQTNTNEYY 1118
>gi|2982915 (AE000677) putative protein [Aquifex aeolicus]
Length = 400
Score = 31.3 bits (69), Expect = 8.5
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 491 KLKELKKTKQQDLKLIKQEIEFXXXXXXXXXXXVTEYKNIEKKQNVYNGFVEEL--THKI 318
K++E ++ ++++ LIK +IE + + +EKK+ N E+L K
Sbjct: 134 KVEEERERLKKEISLIKLQIEQKERELERAKEAQEKLEEVEKKEKEVNKLKEKLRELEKN 193
Query: 317 LEKEKEVNNFTLKIKEIDVLEQNKNQY 237
L+K+KE KE +LE N+ +
Sbjct: 194 LKKQKE--------KEEKLLESNRKLF 212
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 17, 1999 5:33 AM
Number of letters in database: 113,023,754
Number of sequences in database: 369,800
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89780110
Number of Sequences: 369800
Number of extensions: 1439564
Number of successful extensions: 7001
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 6939
Number of HSP's gapped (non-prelim): 102
length of query: 271
length of database: 113023754
effective HSP length: 54
effective length of query: 216
effective length of database: 93054554
effective search space: 20099783664
effective search space used: 20099783664
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 69 (31.3 bits)