BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 11VII7R
(850 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
369,800 sequences; 113,023,754 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|2366752|dbj|BAA22084| (D32053) Lysyl tRNA Synthetase [Homo sa... 249 2e-65
gi|2501023|sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 249 2e-65
gi|505108|dbj|BAA06688| (D31890) similar to lysyl tRNA synthetas... 249 2e-65
gi|586059|sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 246 1e-64
gi|3864|emb|CAA39699| (X56259) lysine--tRNA ligase [Saccharomyce... 244 6e-64
gi|2501024|sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (L... 243 9e-64
gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE, CYTOPLASMI... 243 1e-63
gi|4325324|gb|AAD17333| (AF125574) lysyl-tRNA synthetase; LysRS ... 231 6e-60
gi|2501025|sp|Q43776|SYK_LYCES LYSYL-TRNA SYNTHETASE (LYSINE--TR... 223 1e-57
gi|1174526|sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 196 2e-49
gi|135135|sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TR... 194 9e-49
gi|68526|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6) - Escheric... 194 9e-49
gi|730871|sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 191 6e-48
gi|68527|pir||SYECKU lysine--tRNA ligase (EC 6.1.1.6), thermoind... 190 8e-48
gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna Synthetase (Lysu) (E.C... 190 8e-48
gi|464826|sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUC... 190 8e-48
gi|730872|sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 189 2e-47
gi|2961644 (AF052056) lysyl-tRNA synthetase [Campylobacter jejuni] 189 2e-47
gi|2501017|sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TR... 181 5e-45
gi|4154685 (AE001455) LYSYL-TRNA SYNTHETASE [Helicobacter pylori... 179 2e-44
gi|586058|sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 178 4e-44
gi|3329245 (AE001350) Lysyl tRNA Synthetase [Chlamydia trachomatis] 177 7e-44
gi|2501020|sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TR... 176 2e-43
gi|2983651 (AE000728) lysyl-tRNA synthetase [Aquifex aeolicus] 174 6e-43
gi|2501021|sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TR... 173 2e-42
gi|4377254|gb|AAD19069| (AE001673) Lysyl tRNA Synthetase [Chlamy... 173 2e-42
gi|2501016|sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TR... 171 5e-42
gi|3582260 (M27221) lysyl-tRNA synthetase [Sinorhizobium meliloti] 169 2e-41
gi|2127598|pir||S69892 probable lysyl-tRNA synthetase - Mycoplas... 168 4e-41
gi|146689 (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [... 168 6e-41
gi|1174528|sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TR... 165 4e-40
gi|2501022|sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TR... 164 5e-40
gi|1351162|sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TR... 162 3e-39
gi|1838991|emb|CAB06635| (Z85982) lysX [Mycobacterium tuberculosis] 159 2e-38
gi|2501018|sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TR... 157 7e-38
gi|2501019|sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 157 1e-37
gi|3122897|sp|O06284|SYK_MYCTU LYSYL-TRNA SYNTHETASE (LYSINE--TR... 153 1e-36
gi|3766370|emb|CAA21422| (AL031907) lysyl-trna synthetase [Schiz... 145 4e-34
gi|1351160|sp|P32048|SYKM_YEAST LYSYL-TRNA SYNTHETASE, MITOCHOND... 121 6e-27
gi|450763|emb|CAA40634| (X57360) lysine--tRNA ligase [Saccharomy... 108 5e-23
gi|3915067|sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTA... 76 2e-13
gi|4155111 (AE001489) ASPARTYL-TRNA SYNTHETASE [Helicobacter pyl... 73 3e-12
gi|3024680|sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTA... 73 3e-12
gi|2500967|sp|Q48979|SYD_MYCCA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 71 1e-11
gi|4378708|gb|AAD19636| (AF108665) lysyl-tRNA synthetase homolog... 68 7e-11
gi|1174503|sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTA... 66 3e-10
gi|1074996|pir||I64097 lysyl-tRNA synthetase analog (genX) homol... 66 3e-10
gi|1174524|sp|P43826|SYK3_HAEIN HYPOTHETICAL LYSYL-TRNA SYNTHETA... 66 3e-10
gi|2500973|sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTA... 66 4e-10
gi|4388836|pdb|1B8A|A Chain A, Aspartyl Trna Synthetase From Pyr... 66 4e-10
gi|2500971|sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTA... 65 7e-10
gi|3915063|sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 64 1e-09
gi|3328981 (AE001325) Aspartyl tRNA Synthetase [Chlamydia tracho... 63 2e-09
gi|135102|sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 62 4e-09
gi|3915068|sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTA... 62 5e-09
gi|4101633 (AF005272) lysyl-tRNA synthetase homolog [Haemophilus... 62 6e-09
gi|3122885|sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 61 1e-08
gi|3122880|sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 61 1e-08
gi|3323310 (AE001266) aspartyl-tRNA synthetase (aspS) [Treponema... 61 1e-08
gi|2500972|sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 61 1e-08
gi|2500968|sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTA... 60 2e-08
gi|3257434|dbj|BAA30117| (AP000004) 438aa long hypothetical aspa... 59 4e-08
gi|4376961|gb|AAD18801| (AE001648) Aspartyl tRNA Synthetase [Chl... 59 4e-08
gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 59 6e-08
gi|3122882|sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTA... 58 1e-07
gi|549026|sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 58 1e-07
gi|3875743|emb|CAB04081| (Z81497) similar to aspartyl-tRNA synth... 57 1e-07
gi|1351148|sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTA... 57 2e-07
gi|135138|sp|P03812|SYK3_ECOLI HYPOTHETICAL LYSYL-TRNA SYNTHETAS... 56 3e-07
gi|1361210|pir||S56383 lysyl-tRNA synthetase homolog protein gen... 56 3e-07
gi|4455210|emb|CAB36533| (AL035440) putative aspartate-tRNA liga... 56 4e-07
gi|135101|sp|P15179|SYDM_YEAST ASPARTYL-TRNA SYNTHETASE, MITOCHO... 56 4e-07
gi|551785 (J01611) gene x protein (putative); putative [Escheric... 55 6e-07
gi|78609|pir||A04437 hypothetical protein F-162 - Escherichia co... 55 6e-07
gi|1064982|pdb|1ASY|A Saccharomyces cerevisiae >gi|1064984|pdb|1... 55 8e-07
gi|135100|sp|P04802|SYDC_YEAST ASPARTYL-TRNA SYNTHETASE, CYTOPLA... 55 8e-07
gi|3947886 (AF001831) pyruvate oxidase [Salmonella typhimurium] 54 1e-06
gi|3298338|dbj|BAA31457| (AB010464) aspartyl tRNA synthetase [Ha... 54 1e-06
gi|3860712|emb|CAA14613| (AJ235270) ASPARAGINYL-TRNA SYNTHETASE ... 53 2e-06
gi|3618213|emb|CAA20876| (AL031579) ASPARTYL-TRNA SYNTHETASE [Sc... 52 4e-06
gi|1127124|pdb|1KRT| Mol_id: 1; Molecule: Lysyl-Trna Synthetas... 52 5e-06
gi|3845470|emb|CAA19270| (AL023705) hypothetical protein [Schizo... 51 9e-06
gi|4557513|oth|NP_001340|PDARS aspartyl-tRNA synthetase >gi|1350... 51 9e-06
gi|549025|sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 51 1e-05
gi|2500969|sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 51 1e-05
gi|135099|sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE-... 51 1e-05
gi|3323370 (AE001271) lysyl-tRNA synthetase (lysS-2) [Treponema ... 49 5e-05
gi|1169858|sp|P43151|GBA_LEIDO GUANINE NUCLEOTIDE-BINDING PROTEI... 41 0.011
gi|2983331 (AE000706) lysyl-tRNA synthetase (genX) homolog [Aqui... 40 0.018
gi|3122881|sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTA... 40 0.024
gi|3549678|emb|CAA20589| (AL031394) putative aspartate--tRNA lig... 38 0.091
gi|4127381|emb|CAA09487| (AJ011104) elongation factor G [Apple p... 35 0.79
gi|3377724 (AF079365) silent surface layer protein [Lactobacillu... 35 0.79
gi|2500990|sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHE... 34 1.0
gi|2650424 (AE001091) 2-isopropylmalate synthase (leuA-2) [Archa... 34 1.4
gi|2128703|pir||F64444 hypothetical protein MJ1159 - Methanococc... 33 3.1
gi|2305222 (AF012089) phenylalanyl tRNA synthetase [Drosophila m... 32 4.0
gi|541344|pir||S42927 probable transport protein - Staphylococcu... 32 5.2
gi|1086133|pir||S42931 potential ABC transporter - Staphylococcu... 32 5.2
gi|3758843|emb|CAB11128| (Z98551) predicted using hexExon; MAL3P... 31 9.0
gi|2833489|sp|Q57242|UUP1_HAEIN ABC TRANSPORTER ATP-BINDING PROT... 31 9.0
>gi|2366752|dbj|BAA22084| (D32053) Lysyl tRNA Synthetase [Homo sapiens]
Length = 597
Score = 249 bits (629), Expect = 2e-65
Identities = 130/277 (46%), Positives = 183/277 (65%), Gaps = 2/277 (0%)
Query: 831 ETDSANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK-S 655
E +S + N+ +Y R ++I G++ YPHKFHV ++ + KYS Q +
Sbjct: 67 EEESVDPNQ----YYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLT 122
Query: 654 EEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDI 478
+ + +AGR+ A R + G++ FY + +G +Q++ + N + + + + ++RGDI
Sbjct: 123 DITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFI-HINNKLRRGDI 181
Query: 477 VGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESR 298
+G G PGKTK ELSI +I +LSPCL LP HFGLKD E LN R
Sbjct: 182 IGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVR 241
Query: 297 NRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPE 118
+FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKPFIT+HNEL N Y+R++PE
Sbjct: 242 QKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPE 301
Query: 117 LYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
LYHK L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 302 LYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|2501023|sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (KIAA0070)
Length = 597
Score = 249 bits (629), Expect = 2e-65
Identities = 130/277 (46%), Positives = 183/277 (65%), Gaps = 2/277 (0%)
Query: 831 ETDSANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK-S 655
E +S + N+ +Y R ++I G++ YPHKFHV ++ + KYS Q +
Sbjct: 67 EEESVDPNQ----YYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLT 122
Query: 654 EEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDI 478
+ + +AGR+ A R + G++ FY + +G +Q++ + N + + + + ++RGDI
Sbjct: 123 DITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFI-HINNKLRRGDI 181
Query: 477 VGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESR 298
+G G PGKTK ELSI +I +LSPCL LP HFGLKD E LN R
Sbjct: 182 IGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVR 241
Query: 297 NRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPE 118
+FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKPFIT+HNEL N Y+R++PE
Sbjct: 242 QKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPE 301
Query: 117 LYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
LYHK L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 302 LYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|505108|dbj|BAA06688| (D31890) similar to lysyl tRNA synthetase. [Homo sapiens]
Length = 601
Score = 249 bits (629), Expect = 2e-65
Identities = 130/277 (46%), Positives = 183/277 (65%), Gaps = 2/277 (0%)
Query: 831 ETDSANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK-S 655
E +S + N+ +Y R ++I G++ YPHKFHV ++ + KYS Q +
Sbjct: 71 EEESVDPNQ----YYKIRSQAIHQLKVNGEDPYPHKFHVDISLTDFIQKYSHLQPGDHLT 126
Query: 654 EEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDI 478
+ + +AGR+ A R + G++ FY + +G +Q++ + N + + + + ++RGDI
Sbjct: 127 DITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFI-HINNKLRRGDI 185
Query: 477 VGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESR 298
+G G PGKTK ELSI +I +LSPCL LP HFGLKD E LN R
Sbjct: 186 IGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVR 245
Query: 297 NRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPE 118
+FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKPFIT+HNEL N Y+R++PE
Sbjct: 246 QKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPE 305
Query: 117 LYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
LYHK L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 306 LYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 344
>gi|586059|sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|543180|pir||S43187 lysine--tRNA ligase (EC 6.1.1.6)
- long-tailed hamster >gi|469122|emb|CAA83505| (Z31711)
Lysyl tRNA Synthetase [Cricetulus longicaudatus]
Length = 597
Score = 246 bits (622), Expect = 1e-64
Identities = 125/264 (47%), Positives = 178/264 (67%), Gaps = 2/264 (0%)
Query: 792 FYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK-SEEEVSMAGRVIAT 616
+Y R ++I G++ YPHKFHV ++ + +YS Q ++ + +AGR+ A
Sbjct: 76 YYKIRSQAIHQLKVSGEDPYPHKFHVDISLTQFIQEYSQLQPGDHLTDITLKVAGRIHAK 135
Query: 615 R-NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTD 439
R + G++ FY + +G +Q++ + N + + ++ + ++RGDI+G G PGKTK
Sbjct: 136 RASGGKLIFYDLRGEGVKLQVMANSRNYKSEEEFVR-INNKLRRGDIIGVQGNPGKTKKG 194
Query: 438 ELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYL 259
ELSI +I +LSPCL LP HFGLKD E LN R +FI R+K+I Y+
Sbjct: 195 ELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLILNDFVRQKFIVRAKIITYI 254
Query: 258 RNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNR 79
R+FL + F+E+ETP++N IPGGA AKPFIT+HNEL N Y+R++PELYHK L+VGG++R
Sbjct: 255 RSFLDELGFLEIETPMMNIIPGGAVAKPFITYHNELDMNLYMRIAPELYHKMLVVGGIDR 314
Query: 78 VFEIGKQFRNEGIDLTHNPEFTSCEF 1
V+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 315 VYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|3864|emb|CAA39699| (X56259) lysine--tRNA ligase [Saccharomyces cerevisiae]
Length = 591
Score = 244 bits (616), Expect = 6e-64
Identities = 125/247 (50%), Positives = 173/247 (69%), Gaps = 7/247 (2%)
Query: 741 NVYPHKFHVKNTIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATRNIG-RVNFYKILDDGE 568
N YPHKFHV + E +KY + EE+VS+AGR+ A R G ++ FY + DG
Sbjct: 91 NPYPHKFHVSISNPEFLAKYVHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGV 150
Query: 567 IIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTD-----ELSIFVDDIIIL 403
+Q++ + D ++ K+ +KRGDIVG GY G+T+ E+S+FV + +L
Sbjct: 151 EVQLMSQLQDYHDPESYEKDH-DLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLL 209
Query: 402 SPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEV 223
+PCL LP +HFG KD E +N ++RNRFITRS++I Y+R FL Q++FIEV
Sbjct: 210 TPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRKFLDQRKFIEV 269
Query: 222 ETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEG 43
ETP++N I GGA AKPFIT HN+L + Y+R++PEL+ K+L+VGGL+RV+EIG+QFRNEG
Sbjct: 270 ETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEG 329
Query: 42 IDLTHNPEFTSCEF 1
ID+THNPEFT+CEF
Sbjct: 330 IDMTHNPEFTTCEF 343
>gi|2501024|sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1086773 (U41105) coded for by C. elegans cDNA
yk124d11.3; coded for by C. elegans cDNA yk48a4.3; coded
for by C. elegans cDNA yk124d11.5; coded for by C.
elegans cDNA cm7h5; coded for by C. elegans cDNA cm7a10;
similar to class II aminoacyl-tRNA sy...
Length = 572
Score = 243 bits (615), Expect = 9e-64
Identities = 129/277 (46%), Positives = 175/277 (62%), Gaps = 1/277 (0%)
Query: 831 ETDSANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSE 652
E D ++ E ++ R+ I G N +PHKF+V ++ + +KY+ + E
Sbjct: 47 EADPSDPQE----YFNMRVRMIEARRAAGDNPFPHKFNVTISLTDFITKYTPLEKEQVVE 102
Query: 651 EEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIV 475
E VS+AGR+ + R G ++ FY I +G IQI+ A G + + IKRGDIV
Sbjct: 103 EIVSVAGRIHSKRESGSKLVFYDIHGEGTHIQIMANAK-FHTGDVDFVTLHDRIKRGDIV 161
Query: 474 GFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRN 295
GFTG +TK ELS+ ++I+ L+PCL LP HFGLKD E LN ++
Sbjct: 162 GFTGRATRTKAGELSLIPNEILQLTPCLHMLPHSHFGLKDKELRFRKRYLDLILNPRVKD 221
Query: 294 RFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPEL 115
F+ RSK+I +LR +L F+EVETPI+N I GGA AKPFIT HN+L N +LRV+PEL
Sbjct: 222 NFVIRSKIITFLRRYLDNLGFLEVETPIMNQIAGGATAKPFITHHNDLDMNLFLRVAPEL 281
Query: 114 YHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
YHK L+VGG++RV+E+G+ FRNEGIDLTHNPEFT+CEF
Sbjct: 282 YHKMLVVGGIDRVYEVGRLFRNEGIDLTHNPEFTTCEF 319
>gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE, CYTOPLASMIC (LYSINE--TRNA LIGASE) (LYSRS)
>gi|68528|pir||SYBYKT lysine--tRNA ligase (EC 6.1.1.6) -
yeast (Saccharomyces cerevisiae) >gi|171799 (J04186)
lysyl-tRNA synthetase [Saccharomyces cerevisiae]
>gi|1122359|emb|CAA92376| (Z68196) Krs1p [Saccharomyces
cerevisiae] >gi|1431484|emb|CAA98863| (Z74333) ORF
YDR037w [Saccharomyces cerevisiae]
Length = 591
Score = 243 bits (613), Expect = 1e-63
Identities = 125/247 (50%), Positives = 173/247 (69%), Gaps = 7/247 (2%)
Query: 741 NVYPHKFHVKNTIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATRNIG-RVNFYKILDDGE 568
N YPHKFHV + E +KY+ + EE+VS+AGR+ A R G ++ FY + DG
Sbjct: 91 NPYPHKFHVSISNPEFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGV 150
Query: 567 IIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTD-----ELSIFVDDIIIL 403
+Q++ + D + K+ +KRGDIVG GY G+T+ E+S+FV + +L
Sbjct: 151 EVQLMSQLQDYCDPDSYEKDH-DLLKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLL 209
Query: 402 SPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEV 223
+PCL LP +HFG KD E +N ++RNRFITRS++I Y+R FL Q++FIEV
Sbjct: 210 TPCLHMLPADHFGFKDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEV 269
Query: 222 ETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEG 43
ETP++N I GGA AKPFIT HN+L + Y+R++PEL+ K+L+VGGL+RV+EIG+QFRNEG
Sbjct: 270 ETPMMNVIAGGATAKPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEG 329
Query: 42 IDLTHNPEFTSCEF 1
ID+THNPEFT+CEF
Sbjct: 330 IDMTHNPEFTTCEF 343
>gi|4325324|gb|AAD17333| (AF125574) lysyl-tRNA synthetase; LysRS [Arabidopsis thaliana]
Length = 626
Score = 231 bits (582), Expect = 6e-60
Identities = 130/273 (47%), Positives = 178/273 (64%), Gaps = 25/273 (9%)
Query: 819 ANTNEATDA--FYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEE- 649
A +E DA +Y RL+ ++ +G+N YPHKF V +I + Y + + E
Sbjct: 79 AADDEEMDATQYYENRLKYLAAEKAKGENPYPHKFAVSMSIPKYIETYGSLNNGDHVENA 138
Query: 648 EVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
E S+AGR+++ R+ ++ FY + D +Q++ A+ + + ++ N KRGDIVG
Sbjct: 139 EESLAGRIMSKRSSSSKLFFYDLHGDDFKVQVMADASKSGLDEAEFLKLHSNAKRGDIVG 198
Query: 471 FTGYPGKTKTDELSIFVDDIIILSPCLRTLP---------------------VEHFGLKD 355
G+PGKTK ELSIF I+LS CL +P E + LKD
Sbjct: 199 VIGFPGKTKRGELSIFPRSFILLSHCLHMMPRKADNVNAKKPEIWVPGQTRNPEAYVLKD 258
Query: 354 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKP 175
E LN+E R F TR+K+I+Y+R FL K F+EVETP++N I GGAAA+P
Sbjct: 259 QESRYRQRHLDMILNVEVRQIFRTRAKIISYVRRFLDNKNFLEVETPMMNMIAGGAAARP 318
Query: 174 FITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
F+T HN+L Y+R++PELY K+LIVGGL RV+EIGKQFRNEGIDLTHNPEFT+CEF
Sbjct: 319 FVTHHNDLDMRLYMRIAPELYLKQLIVGGLERVYEIGKQFRNEGIDLTHNPEFTTCEF 376
>gi|2501025|sp|Q43776|SYK_LYCES LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1147585|emb|CAA64223| (X94451) Lysyl-tRNA synthetase
[Lycopersicon esculentum]
Length = 588
Score = 223 bits (563), Expect = 1e-57
Identities = 124/279 (44%), Positives = 178/279 (63%), Gaps = 36/279 (12%)
Query: 840 KSMETDSANTNEATDA--FYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQS 667
+ ME + N+ D + RL +I + + G N YPHKF + +I E S+Y+ +
Sbjct: 39 RQMEQHNLPENDDLDPTQYLANRLRNIESLRESGINPYPHKFFITMSIPEFISRYAHLNT 98
Query: 666 NSKSEE-EVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNI 493
E+ ++S+AGRVI+ R + ++ FY++L G +Q++ A +++ +
Sbjct: 99 GEFPEDIDMSLAGRVISKRASSSKLYFYELLGGGARVQVLASARDSDVDAVQFSNYQSGV 158
Query: 492 KRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLP---------------------- 379
KRGDI+G GYPGK+K ELSIF I+L+PCL LP
Sbjct: 159 KRGDIIGVRGYPGKSKRGELSIFAKPFIVLAPCLHMLPRRLTSSIVDETRTQNFQGITAY 218
Query: 378 ----------VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFI 229
E + L+D E +N E R F TR+++I+Y+R+FL EF+
Sbjct: 219 DTWTPGDLRNPESYVLRDQETRYRQRYLDLMMNPEVRALFRTRARIISYIRSFLDNLEFL 278
Query: 228 EVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRN 49
EVETP +N GGA+A+PFIT HNEL + +RVSPELY KKL+VGG +RV+E+GK FRN
Sbjct: 279 EVETPSMNLTAGGASARPFITHHNELDTELLIRVSPELYLKKLVVGGFDRVYELGKHFRN 338
Query: 48 EGIDLTHNPEFTSCE 4
EG+DLTH+PEFT CE
Sbjct: 339 EGMDLTHSPEFTMCE 353
>gi|1174526|sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1074993|pir||D64110 lysine--tRNA ligase (EC 6.1.1.6)
- Haemophilus influenzae (strain Rd KW20) >gi|1574141
(U32800) lysyl-tRNA synthetase (lysU) [Haemophilus
influenzae Rd]
Length = 502
Score = 196 bits (493), Expect = 2e-49
Identities = 108/262 (41%), Positives = 155/262 (58%), Gaps = 2/262 (0%)
Query: 786 LQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEE--EVSMAGRVIATR 613
L R E ++ +L+ N +P+KF +++ ++Y E+ EV +AGR++ R
Sbjct: 16 LVRREKLA-ALRAKGNAFPNKFRRDALAQDLHNQYDAEDGEILKEKGIEVQVAGRIMTRR 74
Query: 612 NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDEL 433
+G+ F I D IQ+ + +N +G K+ V GDIVG G KTKTDEL
Sbjct: 75 AMGKATFITIQDMSGKIQLYVARDNLPEGV--YKDDVGTWDLGDIVGIKGTLFKTKTDEL 132
Query: 432 SIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRN 253
++ ++ +L+ LR LP + GL D E N ESR FI RSKV+ +R
Sbjct: 133 TVKTTEVQLLTKALRPLPDKFHGLTDQEVRYRQRYLDLISNEESRRTFIIRSKVVAGIRE 192
Query: 252 FLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVF 73
+ I K F+EVETP+L IPGGA+A+PF+T HN L + YLR++PELY K+L+VGG RVF
Sbjct: 193 YFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYLKRLVVGGFERVF 252
Query: 72 EIGKQFRNEGIDLTHNPEFTSCEF 1
E+ + FRNEG+ + HNPEFT E+
Sbjct: 253 ELNRNFRNEGVSVRHNPEFTMLEY 276
>gi|135135|sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|146341
(J03795) herC protein [Escherichia coli] >gi|887840
(U28375) lysyl tRNA synthetase (LysRS), constitutive
[Escherichia coli] >gi|1789256 (AE000372) lysine tRNA
synthetase, constitutive; suppressor of ColE1 mutation
in primer RNA [Escherichia coli]
Length = 505
Score = 194 bits (487), Expect = 9e-49
Identities = 108/259 (41%), Positives = 160/259 (61%), Gaps = 3/259 (1%)
Query: 780 RLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEE---EVSMAGRVIATRN 610
R E ++N +QG +P+ F +T ++ +++ + N + E EV++AGR++ R
Sbjct: 22 RREKLANLREQGI-AFPNDFRRDHTSDQLHAEFDG-KENEELEALNIEVAVAGRMMTRRI 79
Query: 609 IGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELS 430
+G+ +F + D G IQ+ + ++ +G N E K GDI+G G KTKT ELS
Sbjct: 80 MGKASFVTLQDVGGRIQLYVARDDLPEGVYN--EQFKKWDLGDILGAKGKLFKTKTGELS 137
Query: 429 IFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNF 250
I ++ +L+ LR LP + GL+D E N ESRN F RS++++ +R F
Sbjct: 138 IHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQF 197
Query: 249 LIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFE 70
++ + F+EVETP++ IPGGAAA+PFIT HN L + YLR++PELY K+L+VGG RVFE
Sbjct: 198 MVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFE 257
Query: 69 IGKQFRNEGIDLTHNPEFTSCE 4
I + FRNEGI + HNPEFT E
Sbjct: 258 INRNFRNEGISVRHNPEFTMME 279
>gi|68526|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6) - Escherichia coli
Length = 505
Score = 194 bits (487), Expect = 9e-49
Identities = 108/259 (41%), Positives = 160/259 (61%), Gaps = 3/259 (1%)
Query: 780 RLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEE---EVSMAGRVIATRN 610
R E ++N +QG +P+ F +T ++ +++ + N + E EV++AGR++ R
Sbjct: 22 RREKLANLREQGI-AFPNDFRRDHTSDQLHAEFDG-KENEELEALNIEVAVAGRMMTRRI 79
Query: 609 IGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELS 430
+G+ +F + D G IQ+ + ++ +G N E K GDI+G G KTKT ELS
Sbjct: 80 MGKASFVTLQDVGGRIQLYVARDDLPEGVYN--EQFKKWDLGDILGAKGKLFKTKTGELS 137
Query: 429 IFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNF 250
I ++ +L+ LR LP + GL+D E N ESRN F RS++++ +R F
Sbjct: 138 IHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQF 197
Query: 249 LIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFE 70
++ + F+EVETP++ IPGGAAA+PFIT HN L + YLR++PELY K+L+VGG RVFE
Sbjct: 198 MVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFE 257
Query: 69 IGKQFRNEGIDLTHNPEFTSCE 4
I + FRNEGI + HNPEFT E
Sbjct: 258 INRNFRNEGISVRHNPEFTMME 279
>gi|730871|sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|281472|pir||A42609 lysine--tRNA ligase (EC 6.1.1.6)
- Campylobacter jejuni >gi|144208 (M63448) transfer
RNA-Lys synthetase [Campylobacter jejuni]
Length = 501
Score = 191 bits (480), Expect = 6e-48
Identities = 111/261 (42%), Positives = 157/261 (59%), Gaps = 4/261 (1%)
Query: 783 QRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYS-TCQSNSKSEEEVS--MAGRVIATR 613
QR+E K G N YPH + ++K K K+S + K +E V+ +AGR+ R
Sbjct: 9 QRIEKAKELKKLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLR 68
Query: 612 NIGRVNFYKILDDGEIIQIVIIANNA-EDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDE 436
G+ F I D+ +QI ++ E+ T LK KN++ GDIV G+P TKT E
Sbjct: 69 IAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILK---KNLEVGDIVLVKGFPFVTKTGE 125
Query: 435 LSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLR 256
S+ ++ + + + LP ++ GL D E +N+E R F+ RSKV++ +R
Sbjct: 126 FSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKRYVDMIMNVEVRKDFLVRSKVVSLIR 185
Query: 255 NFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRV 76
+F K F+EVETP+++ I GGA AKPF+TFHN L +LR++PELY K+LIVGG V
Sbjct: 186 HFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLIVGGFEAV 245
Query: 75 FEIGKQFRNEGIDLTHNPEFTSCEF 1
FEI + FRNEG+DLTHNPEFT+ EF
Sbjct: 246 FEINRCFRNEGMDLTHNPEFTTIEF 270
>gi|68527|pir||SYECKU lysine--tRNA ligase (EC 6.1.1.6), thermoinducible - Escherichia
coli
Length = 505
Score = 190 bits (479), Expect = 8e-48
Identities = 109/276 (39%), Positives = 165/276 (59%), Gaps = 5/276 (1%)
Query: 831 ETDSANTNEATDAF--YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK 658
E ++ NEA D R E ++ +L+Q +P+ F +T ++ ++ + N +
Sbjct: 3 EQETRGANEAIDFNDELRNRREKLA-ALRQQGVAFPNDFRRDHTSDQLHEEFDA-KDNQE 60
Query: 657 SEE---EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKR 487
E EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + K
Sbjct: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDL 118
Query: 486 GDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNM 307
GDI+G G KT+T ELSI ++ +L+ LR LP + GL+D E N
Sbjct: 119 GDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAND 178
Query: 306 ESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRV 127
+SR F+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR+
Sbjct: 179 KSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRI 238
Query: 126 SPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+PELY K+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 239 APELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna Synthetase (Lysu) (E.C.6.1.1.6) Complexed With
Lysine >gi|1311303|pdb|1LYL|B Chain B, Lysyl-Trna
Synthetase (Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311305|pdb|1LYL|C Chain C, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
Length = 504
Score = 190 bits (479), Expect = 8e-48
Identities = 109/276 (39%), Positives = 165/276 (59%), Gaps = 5/276 (1%)
Query: 831 ETDSANTNEATDAF--YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK 658
E ++ NEA D R E ++ +L+Q +P+ F +T ++ ++ + N +
Sbjct: 2 EQETRGANEAIDFNDELRNRREKLA-ALRQQGVAFPNDFRRDHTSDQLHEEFDA-KDNQE 59
Query: 657 SEE---EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKR 487
E EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + K
Sbjct: 60 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDL 117
Query: 486 GDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNM 307
GDI+G G KT+T ELSI ++ +L+ LR LP + GL+D E N
Sbjct: 118 GDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAND 177
Query: 306 ESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRV 127
+SR F+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR+
Sbjct: 178 KSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRI 237
Query: 126 SPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+PELY K+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 238 APELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 278
>gi|464826|sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361209|pir||S56358 lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|398703|emb|CAA34542| (X16542)
lysyl-tRNA synthetase (AA 1-505) [Escherichia coli]
>gi|536974 (U14003) lysyl-tRNA synthetase [Escherichia
coli] >gi|1790571 (AE000485) lysine tRNA synthetase,
inducible; heat shock protein [Escherichia coli]
Length = 505
Score = 190 bits (479), Expect = 8e-48
Identities = 109/276 (39%), Positives = 165/276 (59%), Gaps = 5/276 (1%)
Query: 831 ETDSANTNEATDAF--YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK 658
E ++ NEA D R E ++ +L+Q +P+ F +T ++ ++ + N +
Sbjct: 3 EQETRGANEAIDFNDELRNRREKLA-ALRQQGVAFPNDFRRDHTSDQLHEEFDA-KDNQE 60
Query: 657 SEE---EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKR 487
E EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + K
Sbjct: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDL 118
Query: 486 GDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNM 307
GDI+G G KT+T ELSI ++ +L+ LR LP + GL+D E N
Sbjct: 119 GDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAND 178
Query: 306 ESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRV 127
+SR F+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR+
Sbjct: 179 KSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRI 238
Query: 126 SPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+PELY K+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 239 APELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|730872|sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1072959|pir||A55589 lysine--tRNA ligase (EC 6.1.1.6)
- Thermus aquaticus >gi|486665|emb|CAA50039| (X70708)
lysine--tRNA ligase [Thermus thermophilus]
Length = 492
Score = 189 bits (476), Expect = 2e-47
Identities = 109/260 (41%), Positives = 153/260 (57%), Gaps = 1/260 (0%)
Query: 783 QRLESISNSLKQGKNVYPHKFHVKNTIKEI-KSKYSTCQSNSKSEEEVSMAGRVIATRNI 607
QRL ++ ++ G YP++F ++ + I K+K + EEEV++AGR++A R +
Sbjct: 7 QRLLNLEALVEAGFAPYPYRFPKTHSAEAILKAKRGAPPESEWPEEEVAVAGRLVALRRM 66
Query: 606 GRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSI 427
G+V F +LD+ IQ+ + T E++K + GDI+G G+P TKT E+++
Sbjct: 67 GKVTFAHLLDETGRIQLYF-----QRDLTPKYELLKKLDVGDILGVRGHPFTTKTGEVTV 121
Query: 426 FVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFL 247
V D L L LP + GL+D E +N E R F RS+++ Y+R F
Sbjct: 122 KVLDWTPLVKSLHPLPDKWHGLRDKEVRYRQRYLDLIVNPEVREVFRRRSEIVRYIRRFF 181
Query: 246 IQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEI 67
K F+EVETPIL GGA A+PF T+HN L FYLR+S ELY K+L+VGG +VFEI
Sbjct: 182 EAKGFLEVETPILQPTTGGAEARPFKTYHNALDHEFYLRISLELYLKRLLVGGYEKVFEI 241
Query: 66 GKQFRNEGIDLTHNPEFTSCE 4
G+ FRNEGID HNPEFT E
Sbjct: 242 GRNFRNEGIDHNHNPEFTMLE 262
>gi|2961644 (AF052056) lysyl-tRNA synthetase [Campylobacter jejuni]
Length = 355
Score = 189 bits (475), Expect = 2e-47
Identities = 110/261 (42%), Positives = 156/261 (59%), Gaps = 4/261 (1%)
Query: 783 QRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYS-TCQSNSKSEEEVS--MAGRVIATR 613
QR+E G N YPH + ++K K K+S + K +E V+ +AGR+ R
Sbjct: 9 QRIEKAKELKNLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLR 68
Query: 612 NIGRVNFYKILDDGEIIQIVIIANNA-EDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDE 436
G+ F I D+ +QI ++ E+ T LK KN++ GDIV G+P TKT E
Sbjct: 69 IAGKSIFANIEDEDTNLQIYFSKDSVGEELYTILK---KNLEVGDIVLVKGFPFVTKTGE 125
Query: 435 LSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLR 256
S+ ++ + + + LP ++ GL D E +N+E R F+ RSKV++ +R
Sbjct: 126 FSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKRYVDMIMNVEVRKDFLVRSKVVSLIR 185
Query: 255 NFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRV 76
+F K F+EVETP+++ I GGA AKPF+TFHN L +LR++PELY K+LIVGG V
Sbjct: 186 HFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLIVGGFEAV 245
Query: 75 FEIGKQFRNEGIDLTHNPEFTSCEF 1
FEI + FRNEG+DLTHNPEFT+ EF
Sbjct: 246 FEINRCFRNEGMDLTHNPEFTTIEF 270
>gi|2501017|sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2313270|gb|AAD07251.1| (AE000538) lysyl-tRNA
synthetase (lysS) [Helicobacter pylori 26695]
Length = 501
Score = 181 bits (455), Expect = 5e-45
Identities = 105/263 (39%), Positives = 154/263 (57%), Gaps = 4/263 (1%)
Query: 789 YLQRLESISNSLKQ-GKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEV---SMAGRVI 622
Y+Q+ +NSL++ GKN Y + T KY+ + + +++ S+ GRV
Sbjct: 6 YIQQRIHKANSLREEGKNPYQNGLKRSLTNAAFLEKYAYVKGLEEPKDKEKCESIVGRVK 65
Query: 621 ATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKT 442
R +G+ F K+ D+ I+Q+ + N D K + K+++ GDIV G+P TKT
Sbjct: 66 LLRLMGKACFIKVEDESTILQVYVSQNELND---EFKSLKKHLEVGDIVLVKGFPFATKT 122
Query: 441 DELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINY 262
ELSI + ILS + LP + GL D E +N ++ F RS +++
Sbjct: 123 GELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPSVKDVFKKRSLIVSS 182
Query: 261 LRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLN 82
+R F + F+EVETP+++ IPGGA A+PFIT+HN L+ YLR++PELY K+LIVGG
Sbjct: 183 VRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVERYLRIAPELYLKRLIVGGFE 242
Query: 81 RVFEIGKQFRNEGIDLTHNPEFTSCEF 1
VFEI + FRNEG+D +HNPEFT EF
Sbjct: 243 AVFEINRNFRNEGMDHSHNPEFTMIEF 269
>gi|4154685 (AE001455) LYSYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 501
Score = 179 bits (450), Expect = 2e-44
Identities = 106/263 (40%), Positives = 153/263 (57%), Gaps = 4/263 (1%)
Query: 789 YLQRLESISNSLKQ-GKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEV---SMAGRVI 622
Y+Q+ +NSL++ GKN Y + T KY+ + + +++ S+ GRV
Sbjct: 6 YIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKGLEEPKDKEKCESVVGRVK 65
Query: 621 ATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKT 442
R +G+ F KI D+ I+Q + N D K + K+++ GDIV G+P TKT
Sbjct: 66 LLRLMGKACFIKIEDESAILQAYVSQNELND---EFKSLKKHLEVGDIVLVKGFPFATKT 122
Query: 441 DELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINY 262
ELSI + ILS + LP + GL D E +N ++ F RS +++
Sbjct: 123 GELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPGVKDVFKKRSLIVSS 182
Query: 261 LRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLN 82
+R F + F+EVETP+++ IPGGA A+PFIT+HN L+ YLR++PELY K+LIVGG
Sbjct: 183 VRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGGFE 242
Query: 81 RVFEIGKQFRNEGIDLTHNPEFTSCEF 1
VFEI + FRNEG+D +HNPEFT EF
Sbjct: 243 AVFEINRNFRNEGMDHSHNPEFTMIEF 269
>gi|586058|sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2127132|pir||S66111 lysyl-tRNA thynthetase -
Bacillus subtilis >gi|467470|dbj|BAA05316| (D26185)
lysyl-tRNA thynthetase [Bacillus subtilis]
>gi|2632349|emb|CAB11858| (Z99104) lysyl-tRNA synthetase
[Bacillus subtilis]
Length = 499
Score = 178 bits (447), Expect = 4e-44
Identities = 102/277 (36%), Positives = 157/277 (55%), Gaps = 2/277 (0%)
Query: 834 METDSANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKS 655
M + N E D ++R + ++ G + + +F + +E+ S Y
Sbjct: 1 MSQEEHNHEELNDQLQVRR-DKMNQLRDNGIDPFGARFERTHQSQEVISAYQDLTKEELE 59
Query: 654 EE--EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGD 481
E+ EV++AGR++ R G+ F + D IQI + ++ D + E+ K+ GD
Sbjct: 60 EKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRKDSVGDDQY---EIFKSSDLGD 116
Query: 480 IVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMES 301
++G TG KT ELS+ +L+ LR LP ++ GLKD E +N +S
Sbjct: 117 LIGVTGKVFKTNVGELSVKATSFELLTKALRPLPDKYHGLKDVEQRYRQRYLDLIVNPDS 176
Query: 300 RNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSP 121
++ FITRSK+I +R +L ++EVETP +++IPGGA+A+PFIT HN L Y+R++
Sbjct: 177 KHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARPFITHHNALDIPLYMRIAI 236
Query: 120 ELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
EL+ K+LIVGGL +V+EIG+ FRNEG+ HNPEFT E
Sbjct: 237 ELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIE 275
>gi|3329245 (AE001350) Lysyl tRNA Synthetase [Chlamydia trachomatis]
Length = 526
Score = 177 bits (445), Expect = 7e-44
Identities = 102/262 (38%), Positives = 158/262 (59%), Gaps = 13/262 (4%)
Query: 789 YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNS------KSEEEVSMAGR 628
YL R + G N YP+++ ++EI++++ + K +V AGR
Sbjct: 13 YLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFAGR 72
Query: 627 VIATRNIGRVNFYKILDDGEIIQIVI------IANNAED-GKTNLKEMVKNIKRGDIVGF 469
++ R++G+ +F +ILD+ IQ++ +A A D G + +K + K + GDI+G
Sbjct: 73 LVLFRSMGKNSFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDILGL 132
Query: 468 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 289
GY T + EL++ V+ + +L L +LP +H GL D E + + R F
Sbjct: 133 EGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWADLISSEDVRKTF 192
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 109
+TRS+++ +R ++ Q+ F+EVETPIL I GGA A PF+T L + +LR+S E+
Sbjct: 193 LTRSRILKLIREYMDQQSFLEVETPILQTIYGGAEATPFVTTLQALHAEMFLRISLEIAL 252
Query: 108 KKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
KKL+VGG++RV+EIGK FRNEGID THNPEFT E
Sbjct: 253 KKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIE 287
>gi|2501020|sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|567884
(L36472) lysyl-tRNA synthetase [Staphylococcus aureus]
Length = 495
Score = 176 bits (442), Expect = 2e-43
Identities = 101/261 (38%), Positives = 145/261 (54%), Gaps = 4/261 (1%)
Query: 786 LQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEE----VSMAGRVIA 619
L R + + G + + KF ++K ++ E+E V++AGR++
Sbjct: 10 LVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMT 69
Query: 618 TRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTD 439
R G+ F + D IQI + + D + +L KN GDIVG G KT T
Sbjct: 70 KRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLW---KNADLGDIVGVEGVMFKTNTG 126
Query: 438 ELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYL 259
ELS+ +L+ LR LP + GL+D E N +S FI RSK+I +
Sbjct: 127 ELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEM 186
Query: 258 RNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNR 79
RN+L K F+EVETP+++ I GGAAA+PF+T HN L + Y+R++ EL+ K+LIVGGL +
Sbjct: 187 RNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEK 246
Query: 78 VFEIGKQFRNEGIDLTHNPEFTSCE 4
V+EIG+ FRNEG+ HNPEFT E
Sbjct: 247 VYEIGRVFRNEGVSTRHNPEFTMIE 271
>gi|2983651 (AE000728) lysyl-tRNA synthetase [Aquifex aeolicus]
Length = 597
Score = 174 bits (437), Expect = 6e-43
Identities = 98/215 (45%), Positives = 131/215 (60%)
Query: 645 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFT 466
VS+AGR+++ R++G+ F I D IQI + + G+ LK I GDIVG
Sbjct: 154 VSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVI--GEEKLKFFNDYIDVGDIVGVR 211
Query: 465 GYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFI 286
G +T T EL++ V++ +L+ L LP + GLKD E N E+R F+
Sbjct: 212 GKLFRTNTGELTVEVEEYQLLAKSLHPLPEKWHGLKDVEVRYRQRYLDLIANPEARRIFM 271
Query: 285 TRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHK 106
R+K+I +R F FIEVETPIL I GA A+PF+T+HN L++ YLR++PELY K
Sbjct: 272 LRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIAPELYLK 331
Query: 105 KLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
+LIVGG RV+EIGK FRNE +D THNPEFT EF
Sbjct: 332 RLIVGGFPRVYEIGKNFRNESVDRTHNPEFTMVEF 366
>gi|2501021|sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1652562|dbj|BAA17483| (D90906) lysyl-tRNA synthetase
[Synechocystis sp.]
Length = 510
Score = 173 bits (433), Expect = 2e-42
Identities = 91/272 (33%), Positives = 154/272 (56%), Gaps = 4/272 (1%)
Query: 819 ANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEVS 640
++++ + + RLE + G N Y + + + + ++++ Y + + + +V+
Sbjct: 4 SHSHSSLEEIRATRLEKAEQLRQLGLNPYAYTWEITHQAQDLQETYRDLSNGEEVDLKVA 63
Query: 639 MAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKR----GDIVG 472
+AGR++A R +G++ F+ + D+ IQ+ + + L+ +K+ GDI+G
Sbjct: 64 IAGRILARRVMGKLAFFTLQDESGTIQLYLEKQRLTEHMPELENAFNLLKKITDVGDILG 123
Query: 471 FTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNR 292
TG +T+ ELS++V +L+ L LP + GL DTE +N R
Sbjct: 124 VTGTLKRTEKGELSVYVQTYAVLTKSLLPLPDKWHGLTDTEKRYRQRYVDLIVNPTVRQT 183
Query: 291 FITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELY 112
F R+++ +R +L ++ FIE+ETP+L GGA A+PFIT HN L YLR++ EL+
Sbjct: 184 FRRRAQITAAIRRYLDKQGFIEIETPVLQGESGGAEARPFITHHNTLGMPLYLRIATELH 243
Query: 111 HKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
K+L+VGG +VFE+G+ FRNEG+ HNPEFTS E
Sbjct: 244 LKRLVVGGFEKVFELGRIFRNEGVSTRHNPEFTSIE 279
>gi|4377254|gb|AAD19069| (AE001673) Lysyl tRNA Synthetase [Chlamydia pneumoniae]
Length = 527
Score = 173 bits (433), Expect = 2e-42
Identities = 101/262 (38%), Positives = 155/262 (58%), Gaps = 13/262 (4%)
Query: 789 YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQ------SNSKSEEEVSMAGR 628
+L R + + G +YP++F + ++IK +++ + + S+S V AGR
Sbjct: 13 FLYRSHKLQELSELGVVLYPYEFPGVFSCEDIKKTFASQELGNSEAAMSRSTPRVRFAGR 72
Query: 627 VIATRNIGRVNFYKILDDGEIIQIVI------IANNAEDGK-TNLKEMVKNIKRGDIVGF 469
++ R +G+ F +ILD + IQ++ + +ED + T +K + K + GDI+G
Sbjct: 73 LVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEITPIKFIEKKLDLGDILGI 132
Query: 468 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 289
GY T + EL++ V+ + +L L +LP +H GL D E + E + F
Sbjct: 133 DGYLFFTHSGELTVLVETVTLLCKSLLSLPDKHAGLSDKEVRYRKRWLDLISSREVSDTF 192
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 109
+ RS +I +RN++ F+EVETPIL NI GGA AKPF T L S +LR+S E+
Sbjct: 193 VKRSYIIKLIRNYMDAHGFLEVETPILQNIYGGAEAKPFTTTMEALHSEMFLRISLEIAL 252
Query: 108 KKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
KK++VGG R++E+GK FRNEGID THNPEFT E
Sbjct: 253 KKILVGGAPRIYELGKVFRNEGIDRTHNPEFTMIE 287
>gi|2501016|sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1359473|emb|CAA86924| (Z46863) lysyl-tRNA-synthase
[Acinetobacter sp. ADP1]
Length = 509
Score = 171 bits (429), Expect = 5e-42
Identities = 96/260 (36%), Positives = 152/260 (57%), Gaps = 4/260 (1%)
Query: 780 RLESISNSLKQ-GKNVYPHKFHVKNTIKEIKSKYST---CQSNSKSEEEVSMAGRVIATR 613
+L+ I + K+ GK+V+P+ F ++ +++ ++ Q + V +AGRV+ R
Sbjct: 26 KLKQIQDKAKETGKSVWPNTFKREHYAADLQEQFKDIDKAQIEGSDKTYVKVAGRVMLNR 85
Query: 612 NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDEL 433
+F I D IQ+ + + + + E +K++ GDI+ GY G++ +L
Sbjct: 86 G----SFMVIQDMTGRIQLYV---DRKGLPADTLETIKSLDLGDIIAAEGYIGRSGKGDL 138
Query: 432 SIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRN 253
+ ++ +L+ LR LP + GL DTE +N E+R F R++V+ +R
Sbjct: 139 YVHLEGFELLTKSLRPLPDKFHGLTDTEAKYRKRYLDLIVNEETRKTFEIRAQVVAGIRA 198
Query: 252 FLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVF 73
FL + F+EVETP+++ IPGGA+A+PF+T HN L YLR++PELY K+L+VGG RVF
Sbjct: 199 FLTNQRFMEVETPMMHVIPGGASAQPFVTHHNALDMELYLRIAPELYLKRLVVGGFERVF 258
Query: 72 EIGKQFRNEGIDLTHNPEFTSCEF 1
EI + FRNEG+ HNPEFT EF
Sbjct: 259 EINRNFRNEGVSTRHNPEFTMIEF 282
>gi|3582260 (M27221) lysyl-tRNA synthetase [Sinorhizobium meliloti]
Length = 498
Score = 169 bits (425), Expect = 2e-41
Identities = 101/246 (41%), Positives = 143/246 (58%), Gaps = 1/246 (0%)
Query: 741 NVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEII 562
+VYP FH T E+ KY+ + +++S E V++AGRV ++RN G F + D I
Sbjct: 31 DVYPAHFHRTLTNAELAEKYAGLEPDTESGETVTVAGRVFSSRNSGM--FMDLHDASGKI 88
Query: 561 QIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTL 382
QI + A + L M I GDI+G TG +TK EL++ +I +L L +
Sbjct: 89 QIFSHKDTAPEEARALLPM---IDLGDIIGVTGEVRRTKRGELTVNAKEITMLCKSLLPM 145
Query: 381 PVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNN 202
P ++ GL D E +N ES+ RF RS++++ LR FL + F+EVETP+L
Sbjct: 146 PEKYHGLADIETRYRKRYLDIMVNEESKLRFQQRSRIVSSLRRFLEDEGFMEVETPMLQP 205
Query: 201 IPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGL-NRVFEIGKQFRNEGIDLTHN 25
I GGA A+PF T HN LK + YLR++ ELY ++V GL ++VFEI + FRNEG+ HN
Sbjct: 206 IYGGATAEPFKTHHNTLKLDMYLRIAAELYLNAILVSGLTDKVFEINRNFRNEGVSTRHN 265
Query: 24 PEFTSCE 4
PEFT E
Sbjct: 266 PEFTMME 272
>gi|2127598|pir||S69892 probable lysyl-tRNA synthetase - Mycoplasma hominis (SGC3)
Length = 488
Score = 168 bits (422), Expect = 4e-41
Identities = 99/234 (42%), Positives = 136/234 (57%), Gaps = 2/234 (0%)
Query: 702 KEIKSKYSTCQSNSKSEEEVSMA--GRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 529
KE+ KY ++ + GR++ R + +L D Q+ I AN
Sbjct: 38 KELNEKYKNLSREDLDKQNLEFVFNGRIMTIRGP-----FIVLQDN-CGQMQIYANKKTL 91
Query: 528 GKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 349
+++ K + GDI+ G KT TD L I DI++L+ L+ LP + GL D E
Sbjct: 92 NESSAKTF-SLMDFGDILSVRGTLSKTNTDALVIKAQDIVLLTKSLKPLPDKFHGLVDPE 150
Query: 348 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 169
+N ++RN F+ R+++I +R + +IEV+TPILN I GGAAAKPFI
Sbjct: 151 ERRRQRYVDLIMNEKTRNTFVMRTQIIKGIREYFDSLNYIEVDTPILNPILGGAAAKPFI 210
Query: 168 TFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
TF+N L NFYLR++ EL KKLIVGGL+RV+EIG+ FRNEG+D THNPEFTS EF
Sbjct: 211 TFYNALNRNFYLRIATELPLKKLIVGGLDRVYEIGRIFRNEGVDTTHNPEFTSIEF 266
>gi|146689 (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [Escherichia
coli]
Length = 501
Score = 168 bits (420), Expect = 6e-41
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 5/276 (1%)
Query: 831 ETDSANTNEATDAF--YLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSK 658
E ++ NEA D R E ++ +L+Q +P+ F +T ++ ++ + N +
Sbjct: 3 EQETRGANEAIDFNDELRNRREKLA-ALRQQGVAFPNDFRRDHTSDQLHEEFDA-KDNQE 60
Query: 657 SEE---EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKR 487
E EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + K
Sbjct: 61 LESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDL 118
Query: 486 GDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNM 307
GDI+G G KT+T ELSI ++ +L+ LR LP + GL+D E N
Sbjct: 119 GDIIG-AGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIAND 177
Query: 306 ESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRV 127
+SR F+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + Y R+
Sbjct: 178 KSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYARI 237
Query: 126 SPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+PELY K+L+VGG RVFE RNEGI HNPEFT E
Sbjct: 238 APELYLKRLVVGGFERVFE--HVTRNEGI-RRHNPEFTMME 275
>gi|1174528|sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|581319|emb|CAA52877| (X74912) putative lysyl-tRNA
synthetase [Mycoplasma hominis]
Length = 488
Score = 165 bits (413), Expect = 4e-40
Identities = 97/234 (41%), Positives = 134/234 (56%), Gaps = 2/234 (0%)
Query: 702 KEIKSKYSTC--QSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 529
KE+ KY + K E GR++ R + +L D Q+ I AN
Sbjct: 38 KELNEKYKNLSREDTDKQNTEFVFNGRIMTIRGP-----FIVLQDN-CGQMQIYANKKTL 91
Query: 528 GKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 349
+++ K + GDI+ G KT TD L + D++ L+ L+ LP + GL D E
Sbjct: 92 NESSAKTF-SLMDFGDILSVRGTLSKTNTDALVMKAQDMVTLTKSLKPLPDKFHGLVDPE 150
Query: 348 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 169
+N ++RN F+ R+++I +R + +IEV+TPILN + GGAAAKPFI
Sbjct: 151 ERRRQRYVDLMMNEKTRNTFVMRTQIIKGIREYFDSLNYIEVDTPILNPMLGGAAAKPFI 210
Query: 168 TFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
TF+N NFYLR++ EL KKLIVGGL+RV+EIG+ FRNEG+D THNPEFTS EF
Sbjct: 211 TFYNATNRNFYLRIATELPLKKLIVGGLDRVYEIGRMFRNEGVDTTHNPEFTSIEF 266
>gi|2501022|sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1707804|emb|CAA69561| (Y08257) lysyl tRNA synthetase
[Sulfolobus solfataricus]
Length = 494
Score = 164 bits (412), Expect = 5e-40
Identities = 103/260 (39%), Positives = 139/260 (52%), Gaps = 3/260 (1%)
Query: 783 QRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEE---EVSMAGRVIATR 613
+R++ + K G YPHK+ V + IK+IK + Q N E +S AGRV R
Sbjct: 8 RRVKIVEELRKNGIEPYPHKYEVTHLIKDIKL-IAKSQGNKSHEPFMFNISTAGRVANIR 66
Query: 612 NIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDEL 433
G+ +F I D+GE +Q+ + ++ K + + RGDI+G G T EL
Sbjct: 67 RHGKASFVDIFDEGEKLQLYM---RVDELKEKYDKFFIYVGRGDIIGVKGDLFYTMKGEL 123
Query: 432 SIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRN 253
S+ V D +LS L P + E N +R R +I +R
Sbjct: 124 SLLVKDYQLLSKALIEPP--DWSKLSPEFRYAHRYVDFLYNDNARKAMEIRYTIIREIRE 181
Query: 252 FLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVF 73
FL K FIEVETPI+ + GGA AKPF T N L ++YLR++ ELY K+ I+GG N+VF
Sbjct: 182 FLYSKGFIEVETPIVQPVYGGALAKPFKTHVNYLNEDWYLRIALELYLKRYIIGGFNKVF 241
Query: 72 EIGKQFRNEGIDLTHNPEFTSCE 4
EIGK FRNE ID+THNPEFT E
Sbjct: 242 EIGKVFRNEDIDVTHNPEFTLLE 264
>gi|1351162|sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361711|pir||A64215 lysine--tRNA ligase (EC 6.1.1.6)
- Mycoplasma genitalium (SGC3) >gi|3844726 (U39693)
lysyl-tRNA synthetase (lysS) [Mycoplasma genitalium]
Length = 490
Score = 162 bits (406), Expect = 3e-39
Identities = 95/241 (39%), Positives = 138/241 (56%), Gaps = 1/241 (0%)
Query: 726 KFHVKNTIKEIKSKYSTCQSNS-KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVI 550
K + ++ K + ++ C K + VS+AGR+IA R F I D +Q+ I
Sbjct: 31 KTSLTHSSKSFQVEFEKCSEEELKKKATVSLAGRIIAIRQ----TFLIIQDFDGQVQLYI 86
Query: 549 IANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEH 370
N + + + GD + +G P TKT L++ V+++ I++ CL P +
Sbjct: 87 ---NKKIHPKLFDYFNEFVDIGDQIVVSGKPMLTKTKVLTLAVEEMKIIAKCLLVPPEKW 143
Query: 369 FGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGG 190
GL D E N+ R+ F+ R+K+I +R+FL Q FIEVETP L + GG
Sbjct: 144 HGLTDIETRARKRFLDLTYNLAMRDVFLKRTKIIKSIRSFLDQNGFIEVETPTLQAVLGG 203
Query: 189 AAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTS 10
A AKPF T +N LK++FYLR++ E+ KKLI+GG N+V+E+GK FRNEG+D THNPEFTS
Sbjct: 204 ANAKPFKTHYNALKADFYLRIANEIALKKLIIGGFNKVYEMGKMFRNEGVDTTHNPEFTS 263
Query: 9 CE 4
E
Sbjct: 264 IE 265
>gi|1838991|emb|CAB06635| (Z85982) lysX [Mycobacterium tuberculosis]
Length = 1172
Score = 159 bits (398), Expect = 2e-38
Identities = 86/217 (39%), Positives = 125/217 (56%)
Query: 654 EEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIV 475
+ VS++GR++ RN G V F ++ D +Q+++ + + G ++ GD+V
Sbjct: 723 QASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDL--GDLV 780
Query: 474 GFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRN 295
TG+ G +KT S+ V ++ CLR LP + GL D E +N ESR
Sbjct: 781 EMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA 840
Query: 294 RFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPEL 115
RS V+ +R L K F+EVETPIL + GGA A+PF+T N + +LR++PEL
Sbjct: 841 LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPEL 900
Query: 114 YHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
Y K+L VGG+ RVFE+G+ FRNEG+D +HNPEFT E
Sbjct: 901 YLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLE 937
>gi|2501018|sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|1263074
(U50826) lysyl-tRNA synthetase [Mycoplasma fermentans]
Length = 488
Score = 157 bits (394), Expect = 7e-38
Identities = 91/237 (38%), Positives = 136/237 (56%), Gaps = 2/237 (0%)
Query: 711 NTIKEIKSKYSTCQSNSKSEEEV--SMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANN 538
+T E+ KY ++V +++GR+I R F + D IQ+ N
Sbjct: 36 STSDELNKKYGQFAREELEAKKVKKNISGRLITARG----PFLVLKDRKGTIQVYF--NK 89
Query: 537 AEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLK 358
E+ + L ++V+ GDI+ G KT T E+++ DI +L+ L+ LP + GL
Sbjct: 90 KENPE--LTKIVETFDLGDILWVRGLLMKTHTCEMTVRAQDIQLLTKALKPLPDKFHGLT 147
Query: 357 DTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAK 178
DTE N ESRN FI R+K++ ++R++ + +++E ETP L++ GAAAK
Sbjct: 148 DTEERYRHRYLDLITNPESRNTFIMRTKIVQWIRDYFNKLDYLEAETPFLHDYLSGAAAK 207
Query: 177 PFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
PF T HN L +F LR++ E+ KKL+VGG RV+E+G+ FRNEG D THNPEFT+ EF
Sbjct: 208 PFTTHHNSLNQDFVLRIATEIPLKKLVVGGFERVYEMGRIFRNEGYDTTHNPEFTTIEF 266
>gi|2501019|sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2146330|pir||S73884 lysine--tRNA ligase (EC 6.1.1.6)
lysS - Mycoplasma pneumoniae (SGC3) (ATCC 29342)
>gi|1674257 (AE000055) Mycoplasma pneumoniae, lysyl-tRNA
synthetase; similar to Swiss-Prot Accession Number
P37477, from B. subtilis [Mycoplasma pneumoniae]
Length = 489
Score = 157 bits (392), Expect = 1e-37
Identities = 98/259 (37%), Positives = 142/259 (53%), Gaps = 2/259 (0%)
Query: 780 RLESISNSLKQGKNVYP-HKFHVKNTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIG 604
RL+ + N + G + Y K ++ + ++ + +V + GR+IA R
Sbjct: 12 RLQKLLNLKQTGNDPYLITKIENTHSAASFQKAFANQSDAELKQYQVILTGRIIALRQ-- 69
Query: 603 RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKN-IKRGDIVGFTGYPGKTKTDELSI 427
F I D +Q+ I A + L E N I GD + TG+P TKT L++
Sbjct: 70 --TFIIIQDFSGKMQLYINKKTAPE----LFEYFNNYIDLGDQIVATGHPMMTKTGVLTL 123
Query: 426 FVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFL 247
V+ + I++ CL+T P + GL D E N F+ R+++I +R FL
Sbjct: 124 NVERLQIVAKCLQTPPEKWHGLTDPEARARKRYLDLTYNRAQVEVFLKRTQIITAIRTFL 183
Query: 246 IQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEI 67
+ F+EVETPIL + GGA AKPF T +N LK +FYLR++ E+ KKLIVGGL +V+E+
Sbjct: 184 NEAGFLEVETPILQAVLGGANAKPFKTHYNALKGDFYLRIANEIALKKLIVGGLPKVYEM 243
Query: 66 GKQFRNEGIDLTHNPEFTSCE 4
G+ FRNEG+D THNPEFTS E
Sbjct: 244 GRMFRNEGVDTTHNPEFTSIE 264
>gi|3122897|sp|O06284|SYK_MYCTU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2113978|emb|CAB08946| (Z95557) lysS [Mycobacterium
tuberculosis]
Length = 505
Score = 153 bits (384), Expect = 1e-36
Identities = 94/273 (34%), Positives = 150/273 (54%)
Query: 822 SANTNEATDAFYLQRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEV 643
+A+T E + R + + L QG++ YP +T+ E+++ + ++ +E+ V
Sbjct: 3 AADTAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTHTLAEVRAAHPDLPIDTATEDIV 62
Query: 642 SMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTG 463
+AGRVI RN G++ F L DG+ Q+ ++ + + G+ L ++ GDIV G
Sbjct: 63 GVAGRVIFARNSGKLCF-ATLQDGDGTQLQVMISLDKVGQAALDAWKADVDLGDIVYVHG 121
Query: 462 YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFIT 283
++ ELS+ D I + LR LPV H + + E + E+R
Sbjct: 122 AVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSE-ESRVRQRYVDLIVRPEARAVARL 180
Query: 282 RSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKK 103
R V+ +R L ++ F+EVETP+L + GGAAA+PF T N L + YLR++PEL+ K+
Sbjct: 181 RIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR 240
Query: 102 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
IVGG ++VFE+ + FRNEG D TH+PEF+ E
Sbjct: 241 CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLE 273
>gi|3766370|emb|CAA21422| (AL031907) lysyl-trna synthetase [Schizosaccharomyces pombe]
Length = 531
Score = 145 bits (362), Expect = 4e-34
Identities = 88/221 (39%), Positives = 135/221 (60%), Gaps = 10/221 (4%)
Query: 666 NSKSEEEVSMA-----GRVIATRNIG-RVNFYKILDDGEIIQIVIIANNA---EDGKTNL 514
N ++ E++M GR+ + R G ++ F+ +L + +Q+V N E+ K
Sbjct: 72 NKITKSEIAMVRYTVCGRISSIRYSGSKLAFFDVLYGNKKLQVVFNKKNIGTEEEMKGKF 131
Query: 513 KEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDII-ILSPCLRTLPVEHFGLKDTEXXXX 337
+K +++GD + +G G++ + ELSI+ ++ +LSPCL +PV+ L + E
Sbjct: 132 IPRLKALQKGDCIQCSGNVGRSGSGELSIYATELPKLLSPCLHPIPVK---LTNYEKRFE 188
Query: 336 XXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHN 157
N +S R ++I +R F ++ F+EVETPIL++ GGA A+PFIT
Sbjct: 189 KRFVDMMSNTKSLELLEKRYRIIESIRKFFSERGFLEVETPILSHHFGGATARPFITSDI 248
Query: 156 ELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
K LR +PEL+ K+L++GG+NRVFE+GK FRNEGID THNPEFTSCE
Sbjct: 249 H-KLPLTLRCAPELWLKQLVIGGMNRVFELGKNFRNEGIDATHNPEFTSCE 298
>gi|1351160|sp|P32048|SYKM_YEAST LYSYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (LYSINE--TRNA
LIGASE) (LYSRS) >gi|418811|pir||S14834 lysine--tRNA
ligase (EC 6.1.1.6) precursor, mitochondrial - yeast
(Saccharomyces cerevisiae) >gi|791113|emb|CAA60187|
(X86470) lysine--tRNA ligase [Saccharomyces cerevisiae]
>gi|1301959|emb|CAA95947| (Z71349) ORF YNL073w
[Saccharomyces cerevisiae]
Length = 576
Score = 121 bits (301), Expect = 6e-27
Identities = 83/215 (38%), Positives = 126/215 (58%), Gaps = 14/215 (6%)
Query: 645 VSMAGRVIATRNIGRVNFYKILDDGEI-------IQIVI----IANNAEDGKTNLKEMVK 499
+S+ GR+ + R G+ + L +G +Q+++ I ++ED K N E +
Sbjct: 101 LSINGRIKSIRFSGQKIVFIDLYNGSSGLKNDTQLQLIVNYNKIGGSSED-KANFSEYMN 159
Query: 498 NIKRGDIVGFTGYPG--KTKTDELSIFVDDI-IILSPCLRTLPVEHFGLKDTEXXXXXXX 328
+K+GD + GYPG +++ LS+ + + I+LS LP L D
Sbjct: 160 FLKKGDYIKALGYPGFSQSRVKMLSLICNKLPIVLSVSQLPLPSR---LNDETKIKSNRV 216
Query: 327 XXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELK 148
LN + R+++I LR FL + F+EVETPIL++ GA AKPFIT +
Sbjct: 217 VDYQLN--GTQTLLVRARIIKLLRKFLDDRNFVEVETPILSSKSNGAMAKPFITSSKDF- 273
Query: 147 SNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
+ LR++PEL+ K+LI+ GL +V+EIGK FRNEGID THN EF++ EF
Sbjct: 274 DHLELRIAPELWLKRLIISGLQKVYEIGKVFRNEGIDSTHNAEFSTLEF 322
>gi|450763|emb|CAA40634| (X57360) lysine--tRNA ligase [Saccharomyces cerevisiae]
Length = 576
Score = 108 bits (267), Expect = 5e-23
Identities = 63/183 (34%), Positives = 101/183 (54%), Gaps = 3/183 (1%)
Query: 549 IANNAEDGKTNLKEMVKNIKRGDIVGFTGYPG--KTKTDELSIFVDDI-IILSPCLRTLP 379
I ++ED K N E + +K+GD + TGYPG +++ S+ + ++LS LP
Sbjct: 144 IGGSSED-KANFSEYMNFLKKGDYIKATGYPGFSQSRVKMTSLMCNKTPMVLSVSQTPLP 202
Query: 378 VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI 199
+ + + R+++I LR F + F+EVETP+ ++
Sbjct: 203 S-----RTNDETKIKSNRVVDYQLNGTQTTTVRARIIKTLRKFTDDRNFVEVETPMTSSK 257
Query: 198 PGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPE 19
GA AKPF+T + + LR++PEL+ K+ ++ GL +V+E+GK FRNEGID THN E
Sbjct: 258 SNGAMAKPFMTSSKDF-DHLELRIAPELWTKRTMISGLQKVYEMGKVFRNEGIDSTHNAE 316
Query: 18 FTSCEF 1
F++ EF
Sbjct: 317 FSTLEF 322
>gi|3915067|sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2984003 (AE000750) aspartyl-tRNA synthetase [Aquifex
aeolicus]
Length = 603
Score = 76.5 bits (185), Expect = 2e-13
Identities = 69/231 (29%), Positives = 109/231 (46%), Gaps = 14/231 (6%)
Query: 693 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 514
++KY S +EV +AG V R+ G V F + D I+Q+V+ + KTN
Sbjct: 10 RTKYCGEVSEEDIGKEVKLAGWVHRKRHHGGVIFIDLRDREGIVQVVV------EEKTNP 63
Query: 513 K--EMVKNIKRGDIVGFTGYPGKT---------KTDELSIFVDDIIILSPC-LRTLPVEH 370
+ E+ +K ++G G K KT + + D I++ + PVE
Sbjct: 64 EAYEVADKLKSEYVIGVVGKVRKRPEGTENPKLKTGYVEVVADRILVFNTSEALPFPVEE 123
Query: 369 FGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILN-NIPG 193
+E +N I R +V RNF ++ FIE+ETP L + P
Sbjct: 124 -ETHVSEETKLKYRYIDLRRESMKNNLIFRHRVYQITRNFFTKEGFIEIETPFLTKSTPE 182
Query: 192 GAAAKPFITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEF 16
GA + F+ FY L SP+L+ + L++ G +R F+I K FR+E + PEF
Sbjct: 183 GA--RDFLVPSRLHPGKFYALPQSPQLFKQILMIAGFDRYFQIVKCFRDEDLRADRQPEF 240
Query: 15 TSCEF 1
T ++
Sbjct: 241 TQIDY 245
>gi|4155111 (AE001489) ASPARTYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 579
Score = 73.0 bits (176), Expect = 3e-12
Identities = 60/231 (25%), Positives = 107/231 (45%), Gaps = 3/231 (1%)
Query: 696 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-ANNAEDGKT 520
++S + T S + + +AG R+ G V F + D ++Q+V ++ A +
Sbjct: 1 MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 519 NLKEMVKNIKRGD--IVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEX 346
++ + +G + G K KT ++ I +++++I + T P+E E
Sbjct: 61 EVRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSA-TPPIEIGNKSVNED 119
Query: 345 XXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFIT 166
++ + F RS+V RN L QK F+E+ETPIL+ A +
Sbjct: 120 LRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGARDYLVP 179
Query: 165 FHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
F L SP+L+ + L+VGG++R F+I + FR+E + PEFT +
Sbjct: 180 SRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQID 233
>gi|3024680|sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2313739|gb|AAD07682.1| (AE000576) aspartyl-tRNA
synthetase (aspS) [Helicobacter pylori 26695]
Length = 577
Score = 72.6 bits (175), Expect = 3e-12
Identities = 63/231 (27%), Positives = 106/231 (45%), Gaps = 3/231 (1%)
Query: 696 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-ANNAEDGKT 520
++S + T S + V +AG R+ G V F + D ++Q+V ++ A +
Sbjct: 1 MRSHFCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 519 NLKEMVKNIKRGDIV--GFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEX 346
++ + +G + G K KT ++ I ++++II + T P+E E
Sbjct: 61 EVRSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKSA-TPPIEIGNKHVNED 119
Query: 345 XXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFIT 166
+ S F RS+V RN L QK F+E+ETPIL+ A +
Sbjct: 120 LRLKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGARDYLVP 179
Query: 165 FHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
F L SP+L+ + L+VGG++R F+I + FR+E + PEFT +
Sbjct: 180 SRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQID 233
>gi|2500967|sp|Q48979|SYD_MYCCA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|530412|emb|CAA83720| (Z33048) Asp-tRNA synthetase
[Mycoplasma capricolum]
Length = 483
Score = 70.6 bits (170), Expect = 1e-11
Identities = 47/168 (27%), Positives = 86/168 (50%), Gaps = 9/168 (5%)
Query: 507 MVKNIKRGDIVGFTGYPGKTK-------TDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 349
++ N+K ++ +G K K T E+ + V D+++++ T V + E
Sbjct: 16 LINNLKNEYVIEISGIVVKRKSVNKELITGEIEVIVKDLLVINKSELTPFVLENDVNVNE 75
Query: 348 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPF 172
+N I R+K+ + +RN+L F+EVETP + P GA + F
Sbjct: 76 DTRLTYRYLDLRRQVMQNNLIIRAKINHIIRNYLTDLNFLEVETPYFAKSTPEGA--RHF 133
Query: 171 ITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ K+ FY L SP+L+ + L++ G++R ++I + FR+E + + PEFT +
Sbjct: 134 LVPSRLNKNKFYALPQSPQLFKQLLMISGIDRYYQIVRCFRDEDLRIDRQPEFTQLD 190
>gi|4378708|gb|AAD19636| (AF108665) lysyl-tRNA synthetase homolog [Buchnera aphidicola]
Length = 324
Score = 68.3 bits (164), Expect = 7e-11
Identities = 39/94 (41%), Positives = 57/94 (60%), Gaps = 6/94 (6%)
Query: 282 RSKVINYLRNFLIQKEFIEVETPILNNIP-GGAAAKPFITFH-----NELKSNFYLRVSP 121
RSK+I +R+F ++K +EVETPIL+ PFIT + N K N +L SP
Sbjct: 17 RSKIIADIRSFFLKKNIMEVETPILSQSGVTDVNLMPFITNYFSFNDNIKKKNLWLITSP 76
Query: 120 ELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
E + K+L+ G +++I + FRN+ HNPEFT E+
Sbjct: 77 EYHMKRLLSAGSGSIYQICRSFRNQEFGQYHNPEFTMLEW 116
>gi|1174503|sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1073870|pir||E64061 aspartate--tRNA ligase (EC
6.1.1.12) - Haemophilus influenzae (strain Rd KW20)
>gi|1573287 (U32717) aspartyl-tRNA synthetase (aspS)
[Haemophilus influenzae Rd]
Length = 588
Score = 66.3 bits (159), Expect = 3e-10
Identities = 61/231 (26%), Positives = 109/231 (46%), Gaps = 8/231 (3%)
Query: 696 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-----ANNAE 532
+++ Y + + ++V+++G V R++G + F + D I+Q+ A A
Sbjct: 2 MRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKYQDALTAA 61
Query: 531 DGKTNLKEMVKNIKRGDIVGFTGYPGKTK-TDELSIFVDDIIILSPCLRTLPVEHFGLKD 355
G N E IK I K T E+ + ++ I + LP++ F +
Sbjct: 62 AGLRN--EFCIQIKGEVIARPDNQINKNMATGEVEVLAKELRIYNAS-DVLPLD-FNQNN 117
Query: 354 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI-PGGAAAK 178
TE E R TR+K+ +++R F+ F+++ETP+L P GA +
Sbjct: 118 TEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGA--R 175
Query: 177 PFITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
++ K FY L SP+L+ + L++ G +R ++I K FR+E + PEFT +
Sbjct: 176 DYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQID 234
>gi|1074996|pir||I64097 lysyl-tRNA synthetase analog (genX) homolog - Haemophilus
influenzae (strain Rd KW20) >gi|1573850 (U32765)
lysyl-tRNA synthetase analog (genX) [Haemophilus
influenzae Rd]
Length = 333
Score = 66.0 bits (158), Expect = 3e-10
Identities = 37/96 (38%), Positives = 54/96 (55%), Gaps = 7/96 (7%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 130
+ R+K+I +R F ++ +EVETP+L+ G TF E + F +L
Sbjct: 27 LKRAKIIAKIRQFFTERGLLEVETPVLSEF--GVTDLHLSTFSTEFLAPFGEQSKTLWLS 84
Query: 129 VSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
SPE + K+L+ G +F+I K FRNE HNPEFT E+
Sbjct: 85 TSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEW 127
>gi|1174524|sp|P43826|SYK3_HAEIN HYPOTHETICAL LYSYL-TRNA SYNTHETASE HOMOLOG (GX)
Length = 323
Score = 66.0 bits (158), Expect = 3e-10
Identities = 37/96 (38%), Positives = 54/96 (55%), Gaps = 7/96 (7%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 130
+ R+K+I +R F ++ +EVETP+L+ G TF E + F +L
Sbjct: 17 LKRAKIIAKIRQFFTERGLLEVETPVLSEF--GVTDLHLSTFSTEFLAPFGEQSKTLWLS 74
Query: 129 VSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
SPE + K+L+ G +F+I K FRNE HNPEFT E+
Sbjct: 75 TSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEW 117
>gi|2500973|sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2129413|pir||JC4352 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus sp >gi|1136773|dbj|BAA08115|
(D45167) aspartyl-tRNA synthetase [Pyrococcus sp.]
Length = 438
Score = 65.6 bits (157), Expect = 4e-10
Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 5/223 (2%)
Query: 693 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 514
++ YS+ + + ++V +AG V +++G + F I D I+QI + L
Sbjct: 3 RTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDP---EL 59
Query: 513 KEMVKNIKRGDIVGFTGYPGKTKTDELS--IFVDDIIILSPCLRTLPVEHFGLKDTEXXX 340
+++ ++ D+V G T +L I + I++L+ LP++ G E
Sbjct: 60 FKLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDT 119
Query: 339 XXXXXXXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 169
L E F RS V +R+F + FIE+ TP I GG P
Sbjct: 120 RLDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 168 TFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHN 25
F + +L SP+LY + ++ GL+RV+EI FR E + T +
Sbjct: 180 YFEEDA----FLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRH 223
>gi|4388836|pdb|1B8A|A Chain A, Aspartyl Trna Synthetase From Pyrococcus Kodakaraensis
>gi|4388837|pdb|1B8A|B Chain B, Aspartyl Trna Synthetase
From Pyrococcus Kodakaraensis
Length = 438
Score = 65.6 bits (157), Expect = 4e-10
Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 5/223 (2%)
Query: 693 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 514
++ YS+ + + ++V +AG V +++G + F I D I+QI + L
Sbjct: 3 RTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDP---EL 59
Query: 513 KEMVKNIKRGDIVGFTGYPGKTKTDELS--IFVDDIIILSPCLRTLPVEHFGLKDTEXXX 340
+++ ++ D+V G T +L I + I++L+ LP++ G E
Sbjct: 60 FKLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDT 119
Query: 339 XXXXXXXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 169
L E F RS V +R+F + FIE+ TP I GG P
Sbjct: 120 RLNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 168 TFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHN 25
F + +L SP+LY + ++ GL+RV+EI FR E + T +
Sbjct: 180 YFEEDA----FLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRH 223
>gi|2500971|sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1652993|dbj|BAA17910| (D90910) aspartyl-tRNA
synthetase [Synechocystis sp.]
Length = 599
Score = 64.8 bits (155), Expect = 7e-10
Identities = 58/216 (26%), Positives = 96/216 (43%), Gaps = 13/216 (6%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
E V++ G V R+ G V F + D I+QI ++ D + + ++ +V
Sbjct: 16 ETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIA----SSPDQTPASYPVAEGLRNEYVVQ 71
Query: 471 FTGYPGKTK---------TDELSIFVDDIIILSPCLRTLPV---EHFGLKDTEXXXXXXX 328
TG K T E+ I+ D II+L+ + LP H + E
Sbjct: 72 VTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEAEQVREDVRLKYR 131
Query: 327 XXXXLNMESRNRFITRSKVINYLRNFLIQKE-FIEVETPILNNIPGGAAAKPFITFHNEL 151
R +V+ +R FL +E F+E+ETPIL A +
Sbjct: 132 YLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEGARDYLVPSRVNP 191
Query: 150 KSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L SP+L+ + L+V G++R ++I + FR+E + PEFT +
Sbjct: 192 GEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQPEFTQLD 240
>gi|3915063|sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2688349 (AE001149) aspartyl-tRNA synthetase (aspS)
[Borrelia burgdorferi]
Length = 506
Score = 64.0 bits (153), Expect = 1e-09
Identities = 46/148 (31%), Positives = 78/148 (52%), Gaps = 6/148 (4%)
Query: 447 KTDELSIFVDDIIILSPCLRTLPVEHFGLKD----TEXXXXXXXXXXXLNMESRNRFITR 280
KT I +I I+S C LP F ++D +E +N+ I R
Sbjct: 7 KTGHFEILAKNIEIISKC-NELP---FMIEDDNNASENSKLEYRYLDLRRDSLKNKIILR 62
Query: 279 SKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYHK 106
+ + +RNFLI+++F+E+ETP + + P G A+ F+ K +FY L SP+LY +
Sbjct: 63 CQATHLIRNFLIKRKFLELETPTFVKSTPEG--ARDFVIPSRIHKGSFYALPQSPQLYKQ 120
Query: 105 KLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+++ G ++ F+I + +R+E PEFT +
Sbjct: 121 LIMIAGFDKYFQIARCYRDEDSRGDRQPEFTQLD 154
>gi|3328981 (AE001325) Aspartyl tRNA Synthetase [Chlamydia trachomatis]
Length = 582
Score = 63.2 bits (151), Expect = 2e-09
Identities = 68/228 (29%), Positives = 108/228 (46%), Gaps = 20/228 (8%)
Query: 687 KYSTCQSNSKS----EEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKT 520
KY T + N S E V ++G V RN G V F + D I QIV ++
Sbjct: 2 KYRTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQIVC----RQEENP 57
Query: 519 NLKEMVKNIKRGDIVGFTGYP---------GKTKTDELSIFVDDIIILSPCLRTLPVEHF 367
L +++ ++ ++ G T + + V + +LS + LP F
Sbjct: 58 ELHQLMDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRA-QNLP---F 113
Query: 366 GLKDTEXXXXXXXXXXXLNMESR-----NRFITRSKVINYLRNFLIQKEFIEVETPILN- 205
+ D ++ R +R + R KV+ R +L ++ F EV TPIL
Sbjct: 114 SISDEHINVNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGK 173
Query: 204 NIPGGAAAKPFITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTH 28
+ P GA + ++ NFY L SP+L+ + L+VGGL+R F+I FR+E +
Sbjct: 174 STPEGA--RDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADR 231
Query: 27 NPEFTSCE 4
PEFT +
Sbjct: 232 QPEFTQID 239
>gi|135102|sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68534|pir||SYECD aspartate--tRNA ligase (EC
6.1.1.12) - Escherichia coli >gi|41015|emb|CAA37856|
(X53863) aspartate-tRNA ligase [Escherichia coli]
>gi|1736513|dbj|BAA15677| (D90829) Aspartate--tRNA
ligase (EC 6.1.1.12) [Escherichia coli] >gi|1788173
(AE000280) aspartate tRNA synthetase [Escherichia coli]
Length = 590
Score = 62.5 bits (149), Expect = 4e-09
Identities = 54/216 (25%), Positives = 102/216 (47%), Gaps = 11/216 (5%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
++V++ G V R++G + F + D I+Q+ + A+ K + ++ +
Sbjct: 16 QQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALK-----LASELRNEFCIQ 70
Query: 471 FTG---------YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXX 319
TG T E+ + + I++ LP++ + +TE
Sbjct: 71 VTGTVRARDEKNINRDMATGEIEVLASSLTIINRA-DVLPLDSNHV-NTEEARLKYRYLD 128
Query: 318 XLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI-PGGAAAKPFITFHNELKSN 142
E R TR+K+ + +R F+ F+++ETP+L P GA + ++ K
Sbjct: 129 LRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGA--RDYLVPSRVHKGK 186
Query: 141 FY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
FY L SP+L+ + L++ G +R ++I K FR+E + PEFT +
Sbjct: 187 FYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQID 233
>gi|3915068|sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2947034 (L43549) aspartyl-tRNA synthetase [Buchnera
aphidicola]
Length = 584
Score = 62.1 bits (148), Expect = 5e-09
Identities = 58/216 (26%), Positives = 102/216 (46%), Gaps = 11/216 (5%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVK--NIKRGDI 478
+ V + G V RN + F + D I+Q+V K N K K N+K
Sbjct: 16 KSVILCGWVHKIRNFSQFIFIDMRDWTGIVQLVF-------EKKNNKVFTKAVNLKNESC 68
Query: 477 VGFTGYPGKTK-------TDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXX 319
+ G K T E+ I V+ I + + + LP+++ + +
Sbjct: 69 IQVIGIVKKRNANNNNLDTGEIEILVNKIKVFN-ISKNLPLDYSNNSNDDIRLKYRYLDL 127
Query: 318 XLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPFITFHNELKSN 142
+ N I R+K+ + +R F+ K F+++ETP L + P G A+ ++ N
Sbjct: 128 RRSELLENLKI-RNKITHLIRIFMENKNFLDIETPFLTKSTPEG--ARDYLVPSRNYPGN 184
Query: 141 FY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
FY L SP+L+ + L++ G+++ ++I K FR+E + PEFT +
Sbjct: 185 FYALPQSPQLFKQILMISGIDKYYQIVKCFRDEDLRSDRQPEFTQID 231
>gi|4101633 (AF005272) lysyl-tRNA synthetase homolog [Haemophilus
paragallinarum]
Length = 322
Score = 61.7 bits (147), Expect = 6e-09
Identities = 37/96 (38%), Positives = 55/96 (56%), Gaps = 7/96 (7%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 130
++R+K+I +R F ++ +EVETPIL+ G TF +L S F +L
Sbjct: 16 LSRAKIIAEIRQFFSERGLLEVETPILSEF--GVTDVHLSTFSTKLISPFQKKEKTLWLS 73
Query: 129 VSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
SPE K+L+ G +F++ K FRNE H+PEFT E+
Sbjct: 74 TSPEYPMKRLLSAGSGAIFQLCKVFRNEEAGKKHSPEFTMLEW 116
>gi|3122885|sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2635219|emb|CAB14714| (Z99118) aspartyl-tRNA
synthetase [Bacillus subtilis]
Length = 592
Score = 60.9 bits (145), Expect = 1e-08
Identities = 60/216 (27%), Positives = 106/216 (48%), Gaps = 14/216 (6%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
E V++ G V R++G + F + D I+Q+V + +++ + E ++N DI G
Sbjct: 18 ESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPDVSKEALA-IAEGIRNEYVLDIQG 76
Query: 471 F-------TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXL 313
T P KT + I D + +L+ +T P F + D
Sbjct: 77 KVVAREEGTVNPN-LKTGAIEIHADGVNVLNAA-KTPP---FAISDQAEEVSEDVRLKHR 131
Query: 312 NMESRNRFI-----TRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNEL 151
++ R + R V +R+FL + F+++ETPIL + P GA + ++
Sbjct: 132 YLDLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPILTGSTPEGA--RDYLVPSRVH 189
Query: 150 KSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ FY L SP+L+ + L+V G+ R ++I + FR+E + PEFT +
Sbjct: 190 EGEFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQPEFTQID 239
>gi|3122880|sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2209068|dbj|BAA20527| (D82887) aspartyl-tRNA
synthetase [Halobacterium salinarum]
Length = 436
Score = 60.9 bits (145), Expect = 1e-08
Identities = 58/202 (28%), Positives = 94/202 (45%), Gaps = 11/202 (5%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
E+ ++AG V R++G + F + D +Q+V ED +L E + + D+V
Sbjct: 17 EDTTIAGHVHELRDLGGILFVIVRDATGRLQVVA----KEDDTPDLFETAEGLSSEDVVQ 72
Query: 471 FTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGL------KDTEXXXXXXXXXXXLN 310
TG T E S + L+P T+ E + KD + L+
Sbjct: 73 VTG------TLEASDQAPGGVELAPTELTVVSEATDVPSIEISKDVDADLSTRLDERHLD 126
Query: 309 MESRNR---FITRSKVINYLRNFLIQKEFIEVETPILNNI--PGGAAAKPFITFHNELKS 145
+ + F RSK + + ++ F EV+TP L+ GGA P + + E
Sbjct: 127 VRKPSTKAVFSLRSKAMGAMTDWFYDNRFEEVDTPELSTAGAEGGADLFPVVYYDKEA-- 184
Query: 144 NFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNE 46
YL SP+LY + L+ G++R+FE+G FR E
Sbjct: 185 --YLSQSPQLYKQILVASGVDRLFEVGHAFRAE 215
>gi|3323310 (AE001266) aspartyl-tRNA synthetase (aspS) [Treponema pallidum]
Length = 602
Score = 60.5 bits (144), Expect = 1e-08
Identities = 59/214 (27%), Positives = 99/214 (45%), Gaps = 15/214 (7%)
Query: 645 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFT 466
V + G V R+ G V+F+ + D I+Q+++ +++ +L V I+ +
Sbjct: 35 VVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIV----SQEENASLWSTVNRIRLECCLAVE 90
Query: 465 GYPGKTK---------TDELSIFVDDIIILSPCLRTLPVEHFGLKDT----EXXXXXXXX 325
G + T E+ + + +LS LP F + D E
Sbjct: 91 GVVRERPPSMINRALHTGEVEVHARTLYVLSENA-VLP---FRVDDVVHAHEDIRLKYRY 146
Query: 324 XXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELK 148
+ + R RS+V +R FL K FIE+ETP + + P GA + F+
Sbjct: 147 LDLRSQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGA--RDFVVPSRVCP 204
Query: 147 SNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
FY L SP+LY + L+V G +R F++ + +R+E PEFT +
Sbjct: 205 GRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQPEFTQID 253
>gi|2500972|sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2127776|pir||B64494 aspartate--tRNA ligase (EC
6.1.1.12) - Methanococcus jannaschii >gi|1592183
(U67596) aspartyl-tRNA synthetase (aspS) [Methanococcus
jannaschii]
Length = 438
Score = 60.5 bits (144), Expect = 1e-08
Identities = 59/222 (26%), Positives = 95/222 (42%), Gaps = 5/222 (2%)
Query: 711 NTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAE 532
N +K ++ YS +EV + G V + R +G++ F + D +QIV
Sbjct: 3 NKMKWRRTHYSADIKPEMDGQEVIIMGWVHSIRALGKIIFVILRDREGTVQIVAPKQKVG 62
Query: 531 DGKTNLKEMVKNIKRGDIVGFTG--YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLK 358
D L +K + D++ G + + I ++ +++ R LP++
Sbjct: 63 D---ELFSQIKKLGAEDVIAVKGKVIANEKAPNGFEILPLELEVINTAKRPLPLDPAEKV 119
Query: 357 DTEXXXXXXXXXXXLNMESRNR-FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGA 187
E L F RS+++ +RN L + FIEV TP + + GG
Sbjct: 120 PAELDTRLENRFLDLRRPKVQAIFKIRSEMLKSVRNTLYNEGFIEVNTPKLVASCTEGGT 179
Query: 186 AAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNE 46
P F E +L SP+LY + L+ GL+RVFEI FR E
Sbjct: 180 ELFPISYFEREA----FLGQSPQLYKQMLMATGLDRVFEIAPIFRAE 222
>gi|2500968|sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2146065|pir||S73434 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Mycoplasma pneumoniae (SGC3) (ATCC
29342) >gi|1673765 (AE000013) Mycoplasma pneumoniae,
aspartyl-tRNA synthetase; similar to Swiss-Prot
Accession Number P36419, from T. aquaticus [Mycoplasma
pneumoniae]
Length = 557
Score = 60.1 bits (143), Expect = 2e-08
Identities = 62/214 (28%), Positives = 93/214 (42%), Gaps = 3/214 (1%)
Query: 645 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFT 466
V++AG V + +G +NF + D IQ+ KE VK + R D+V
Sbjct: 27 VTIAGWVKRIKKLGELNFVIVGDKTNTIQVTC----------KNKEQVKYLTREDLVIVK 76
Query: 465 GYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT-EXXXXXXXXXXXLNMESRNRF 289
G + + I + I L +T P+ D E + R
Sbjct: 77 GKLKRLDSVRFEI-TNPTITLFAKSKTPPLIIEDKTDALEEVRLRYRYLDLRRPVMQKRL 135
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNELKSNFY-LRVSPEL 115
R KV +RN+L Q FIEVETP L + P GA + F+ + +FY L SP++
Sbjct: 136 ALRHKVTLAVRNWLDQMGFIEVETPTLTKSTPEGA--RDFLVPARIREHSFYALPQSPQI 193
Query: 114 YHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
Y + L+VGG + F+I +R+E PE T +
Sbjct: 194 YKQLLMVGGTEKYFQIAHVYRDEDSRKDRQPEHTQID 230
>gi|3257434|dbj|BAA30117| (AP000004) 438aa long hypothetical aspartyl-tRNA synthetase
[Pyrococcus horikoshii]
Length = 438
Score = 58.9 bits (140), Expect = 4e-08
Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 696 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTN 517
+++ YS + + + V +AG V +++G + F I D I+Q+
Sbjct: 2 LRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVSQ---E 58
Query: 516 LKEMVKNIKRGDIVGFTGYPGKTKTDELSIFV--DDIIILSPCLRTLPVEHFGLKDTEXX 343
+ +++ + D++ G T +L V + + ++S LP++ G E
Sbjct: 59 IFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEVIPEKLEVISRAKTPLPLDPTGKVKAELD 118
Query: 342 XXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAA 184
M+ RN F RS V +R F + FIE+ TP I GG
Sbjct: 119 TRLDNRF----MDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGGTE 174
Query: 183 AKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHN 25
P F + +L SP+LY + ++ GL++VFEI FR E + T +
Sbjct: 175 LFPLKYFERDA----FLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRH 223
>gi|4376961|gb|AAD18801| (AE001648) Aspartyl tRNA Synthetase [Chlamydia pneumoniae]
Length = 584
Score = 58.9 bits (140), Expect = 4e-08
Identities = 65/228 (28%), Positives = 104/228 (45%), Gaps = 20/228 (8%)
Query: 687 KYSTCQSNSKSE----EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKT 520
KY T + N + E V +AG V RN G V F + D I QIV ED +
Sbjct: 2 KYRTHRCNELTSNHIGENVQLAGWVHRYRNHGGVVFIDLRDRFGITQIVC----REDEQP 57
Query: 519 NLKEMVKNIKRGDIVGFTGYP---------GKTKTDELSIFVDDIIILSPCLRTLPVEHF 367
L + + ++ ++ G T + + V +LS + LP F
Sbjct: 58 ELHQRLDAVRSEWVLSVRGKVCPRLAGMENPNLATGHIEVEVASFEVLSKS-QNLP---F 113
Query: 366 GLKDTEXXXXXXXXXXXLNMESRN-----RFITRSKVINYLRNFLIQKEFIEVETPILN- 205
+ D ++ R + + R +V+ RNF+ + F E+ TP+L
Sbjct: 114 SIADDHINVNEELRLEYRYLDMRRGDIIEKLLCRHQVMLACRNFMDAQGFTEIVTPVLGK 173
Query: 204 NIPGGAAAKPFITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTH 28
+ P GA + ++ FY L SP+L+ + L+VGGL+R F+I FR+E +
Sbjct: 174 STPEGA--RDYLVPSRIYPGKFYALPQSPQLFKQLLMVGGLDRYFQIATCFRDEDLRADR 231
Query: 27 NPEFTSCE 4
PEF +
Sbjct: 232 QPEFAQID 239
>gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2649677 (AE001040) aspartyl-tRNA synthetase (aspS)
[Archaeoglobus fulgidus]
Length = 430
Score = 58.6 bits (139), Expect = 6e-08
Identities = 57/209 (27%), Positives = 93/209 (44%), Gaps = 10/209 (4%)
Query: 651 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVG 472
++V++ G V R++G + F + D I+QI + + ++ K I+R ++
Sbjct: 15 QKVTLYGWVHEVRDLGGLVFILLRDREGIVQITLPRKFVSK---QVFKLAKKIRRESVIA 71
Query: 471 FTGYPGKTKTDE--LSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESR 298
TG + + + I + I +L+ LP+E TE
Sbjct: 72 VTGEVRREEKAPGGVEIIPESIEVLNEADAPLPLEV-----TEKVPAELDTRLDHRFMDL 126
Query: 297 NR------FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNELKSN 142
R F R +V+ +R FL ++ FIEV TP + GG P F E
Sbjct: 127 RRPRVQAIFRIRHQVMQSVREFLSEEGFIEVHTPKIVSTATEGGTELFPISYFEKEA--- 183
Query: 141 FYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHN 25
+L SP+LY + L+ G +VFEIG FR E + T +
Sbjct: 184 -FLNQSPQLYKQVLMAAGFEKVFEIGPIFRAEEHNTTRH 221
>gi|3122882|sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2621273 (AE000809) aspartyl-tRNA synthetase
[Methanobacterium thermoautotrophicum]
Length = 437
Score = 57.8 bits (137), Expect = 1e-07
Identities = 59/230 (25%), Positives = 106/230 (45%), Gaps = 6/230 (2%)
Query: 693 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 514
++ YS +EV++ G V R++G + F + D +IQI + E +L
Sbjct: 8 RTHYSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEK---DL 64
Query: 513 KEMVKNIKRGDIVGFTGYPGKT--KTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXX 340
+ ++ +K+ +V F G ++ I + +L+ + LP++ E
Sbjct: 65 FKSIRKLKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLNISKQPLPLDPTEKVKAEIDT 124
Query: 339 XXXXXXXXLNMESRNR-FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 169
L S + F +S++++ +R FL ++ F+E+ TP + + GG P
Sbjct: 125 RLDARFLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPIT 184
Query: 168 TFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGID-LTHNPEFTSCE 4
F E +L SP+LY + ++ GL+RV+EI FR E D L H E S +
Sbjct: 185 YFEREA----FLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISID 236
>gi|549026|sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|420805|pir||S33743 aspartate--tRNA ligase (EC
6.1.1.12) - Thermus aquaticus >gi|396501|emb|CAA50282|
(X70943) aspartyl-tRNA synthetase [Thermus thermophilus]
Length = 580
Score = 57.8 bits (137), Expect = 1e-07
Identities = 30/93 (32%), Positives = 52/93 (55%)
Query: 282 RSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKK 103
R +VI + +FL ++ F++VETP L A + + +E + L SP+L+ +
Sbjct: 147 RHRVIKAIWDFLDREGFVQVETPFLTKSTPEGARDFLVPYRHEPGLFYALPQSPQLFKQM 206
Query: 102 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
L+V GL+R F+I + FR+E + P+FT +
Sbjct: 207 LMVAGLDRYFQIARCFRDEDLRADRQPDFTQLD 239
>gi|3875743|emb|CAB04081| (Z81497) similar to aspartyl-tRNA synthetase; cDNA EST yk250e3.3
comes from this gene [Caenorhabditis elegans]
Length = 569
Score = 57.4 bits (136), Expect = 1e-07
Identities = 50/164 (30%), Positives = 84/164 (50%), Gaps = 16/164 (9%)
Query: 495 IKRGDI-VGFTGYPGKTKTDELS----------IFVDDIIILSPCLRTLPVEHFGLKDTE 349
+K GDI V F Y K+ +E S I V+++ +L+ +P+ L D
Sbjct: 54 MKTGDIEVNFQKYYFKSGNNENSNREVFDFLILIDVEELTVLNKATSNIPM----LPDAN 109
Query: 348 XXXXXXXXXXXLNMES---RNRFITRSKVINYLRNFLIQKE-FIEVETPIL-NNIPGGAA 184
+++ S + RS+ ++ +R FL++K F++VETP L PGGAA
Sbjct: 110 ANERTRLKYRYIDLRSDKLQKSLRLRSEFVHNVRRFLVEKSGFVDVETPTLFRRTPGGAA 169
Query: 183 AKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L SP+ + + L+VG ++R F+I + +R+EG PEFT +
Sbjct: 170 EFVVPAPSPNQGLAYSLPQSPQQFKQLLMVGAIDRYFQIARCYRDEGSKGDRQPEFTQVD 229
>gi|1351148|sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1361448|pir||I64203 aspartate--tRNA ligase (EC
6.1.1.12) - Mycoplasma genitalium (SGC3) >gi|3844646
(U39683) aspartyl-tRNA synthetase (aspS) [Mycoplasma
genitalium]
Length = 550
Score = 56.6 bits (134), Expect = 2e-07
Identities = 56/223 (25%), Positives = 102/223 (45%), Gaps = 5/223 (2%)
Query: 669 SNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVKNIK 490
S + + + + G + + +G +NF + D IQ+ +D KE ++ +
Sbjct: 13 STEQLNKTIVIIGWIKRIKKLGEINFIIVGDKSGTIQVT-----CKD-----KEQIQQLT 62
Query: 489 RGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLN 310
R DIV + + + I + S +T P+ +T+ L+
Sbjct: 63 REDIVIVKAKLQRLDSVRFELINPTIKLFSKS-KTPPL--IIEDETDALEEVRLKYRYLD 119
Query: 309 MESR---NRFITRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNELKSN 142
+ R R + R + I +RN+ Q+ FIE+ETP L+ + P GA + F+ K
Sbjct: 120 LRRRLMQKRLLLRHQFILAIRNWFNQQGFIEIETPTLSKSTPEGA--QDFLVPARIRKDC 177
Query: 141 FYLRV-SPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
FY V SP++Y + L++ G+ + F+I + +R+E PE T +F
Sbjct: 178 FYALVQSPQIYKQLLMIAGVEKYFQIARVYRDEDSRKDRQPEHTQIDF 225
>gi|135138|sp|P03812|SYK3_ECOLI HYPOTHETICAL LYSYL-TRNA SYNTHETASE HOMOLOG (GX)
>gi|41552|emb|CAA42604| (X59988) genX [Escherichia coli]
Length = 325
Score = 56.2 bits (133), Expect = 3e-07
Identities = 32/96 (33%), Positives = 53/96 (54%), Gaps = 5/96 (5%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 124
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 17 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 76
Query: 123 PELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
PE + K+L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 77 PEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 117
>gi|1361210|pir||S56383 lysyl-tRNA synthetase homolog protein genX - Escherichia coli
>gi|536999 (U14003) lysyl-tRNA synthetase analog
[Escherichia coli] >gi|1790599 (AE000488) putative
lysyl-tRNA synthetase [Escherichia coli]
Length = 335
Score = 56.2 bits (133), Expect = 3e-07
Identities = 32/96 (33%), Positives = 53/96 (54%), Gaps = 5/96 (5%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 124
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 27 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 86
Query: 123 PELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
PE + K+L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 87 PEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 127
>gi|4455210|emb|CAB36533| (AL035440) putative aspartate-tRNA ligase [Arabidopsis thaliana]
Length = 504
Score = 55.8 bits (132), Expect = 4e-07
Identities = 72/232 (31%), Positives = 103/232 (44%), Gaps = 24/232 (10%)
Query: 696 IKSKYSTCQSNSKSE---EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDG 526
++ K T SN E EVS+ GR+ R +G F + + G +Q V+
Sbjct: 68 VEGKELTDVSNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRVG-- 125
Query: 525 KTNLKEMVKNIKRGDIV---GFTGYPGKT---KTDELSIFVDDIIILSPCLRTLP----- 379
N+ + VK + R +V G +P K T ++ I V + LS L LP
Sbjct: 126 -ANMIKFVKQLSRESVVELIGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVED 184
Query: 378 -------VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVE 220
+E G KDT N F + +V R +L K F+E+
Sbjct: 185 AARSESDIEKSG-KDTRLNNRVLDIRTPANQAI---FRIQCQVQIAFREYLQSKGFLEIH 240
Query: 219 TP--ILNNIPGGAAAKPFITFHNELKSN-FYLRVSPELYHKKLIVGGLNRVFEIGKQFRN 49
TP I + GG+A F + K L SP+L+ + I G + RVFE+G FR
Sbjct: 241 TPKLIAGSSEGGSAV-----FRLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRA 295
Query: 48 EGIDLTHNPEFTSCEF 1
E TH CEF
Sbjct: 296 ED-SFTHR---HLCEF 307
>gi|135101|sp|P15179|SYDM_YEAST ASPARTYL-TRNA SYNTHETASE, MITOCHONDRIAL (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|2144551|pir||SYBYDM aspartate--tRNA ligase
(EC 6.1.1.12), mitochondrial - yeast (Saccharomyces
cerevisiae) >gi|172872 (M26020) aspartyl-tRNA synthetase
[Saccharomyces cerevisiae] >gi|173036 (M24418)
mitochondrial aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1151223 (U43281) Msd1p [Saccharomyces
cerevisiae]
Length = 658
Score = 55.8 bits (132), Expect = 4e-07
Identities = 54/204 (26%), Positives = 96/204 (46%), Gaps = 12/204 (5%)
Query: 615 RNIGRVNFYKILDD--GEIIQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTK- 445
+ +G+ + +L D G+IIQ+V + K ++K D+V G +
Sbjct: 61 KRVGKNLIFGLLRDSNGDIIQLV-----------DNKSLLKGFTLEDVVQAVGILSLKRK 109
Query: 444 -----TDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITR 280
DE + ++DI +L+ + P + K + N + ++ R
Sbjct: 110 LSNEDADEYEVQLEDITVLNASNKK-PAQMQDFKLSAIYPPEFRYLQLRNPKYQDFLKKR 168
Query: 279 SKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAA--KPFITFHNELKSNFY-LRVSPELY 112
S + +RN +F EVETP+L P GA P T ++ K +FY L SP+ Y
Sbjct: 169 SSISKEIRNSFNNFDFTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQY 228
Query: 111 HKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L+ G+N+ +++ + FR+E + PEFT +
Sbjct: 229 KQLLMASGVNKYYQMARCFRDEDLRADRQPEFTQVD 264
>gi|551785 (J01611) gene x protein (putative); putative [Escherichia coli]
Length = 151
Score = 55.0 bits (130), Expect = 6e-07
Identities = 31/96 (32%), Positives = 53/96 (54%), Gaps = 5/96 (5%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 124
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 16 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 75
Query: 123 PELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
P+ + K+L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 76 PQYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 116
>gi|78609|pir||A04437 hypothetical protein F-162 - Escherichia coli (fragment)
Length = 162
Score = 55.0 bits (130), Expect = 6e-07
Identities = 31/96 (32%), Positives = 53/96 (54%), Gaps = 5/96 (5%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 124
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 27 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 86
Query: 123 PELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
P+ + K+L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 87 PQYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 127
>gi|1064982|pdb|1ASY|A Saccharomyces cerevisiae >gi|1064984|pdb|1ASY|B Saccharomyces
cerevisiae >gi|1064986|pdb|1ASZ|A Saccharomyces
cerevisiae >gi|1064988|pdb|1ASZ|B Saccharomyces
cerevisiae
Length = 490
Score = 54.7 bits (129), Expect = 8e-07
Identities = 67/228 (29%), Positives = 101/228 (43%), Gaps = 26/228 (11%)
Query: 687 KYSTCQSNSKSEEEVSMAGRVIATRNIGR-VNFYKILDDGEIIQIVIIANNAEDGKTNLK 511
K+ S++EV RV TR G + F + +IQ ++ AN N+
Sbjct: 28 KFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMV 87
Query: 510 EMVKNIKRGDIVGFTGY------PGKTKT-DELSIFVDDIIILSPCLRTLPVEHFGLKDT 352
+ ++ IV G P K+ T L I + I +S LP+ L+D
Sbjct: 88 KWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPIL---LEDA 144
Query: 351 EXXXXXXXXXXX--LNMESR------------NRFITRSK--VINYLRNFLIQKEFIEVE 220
+N+++R N+ I R + V R +L K+F EV
Sbjct: 145 SRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVH 204
Query: 219 TPILNNIPGGAAAKPF-ITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEG 43
TP L P + F +T+ K YL SP+ ++LIV RV+EIG FR E
Sbjct: 205 TPKLLGAPSEGGSSVFEVTY---FKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAEN 261
Query: 42 IDL-THNPEFTSCE 4
+ H EFT +
Sbjct: 262 SNTHRHMTEFTGLD 275
>gi|135100|sp|P04802|SYDC_YEAST ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|68532|pir||SYBYDC aspartate--tRNA ligase (EC
6.1.1.12), cytosolic - yeast (Saccharomyces cerevisiae)
>gi|3370|emb|CAA27269| (X03606) AspRS (aa 1-557)
[Saccharomyces cerevisiae] >gi|3411|emb|CAA29865|
(X06665) aspartyl tRNA synthase [Saccharomyces
cerevisiae] >gi|1297012|emb|CAA66172| (X97560)
aspartyl-tRNA synthetase [Saccharomyces cerevisiae]
>gi|1360191|emb|CAA97464| (Z73123) ORF YLL018c
[Saccharomyces cerevisiae]
Length = 557
Score = 54.7 bits (129), Expect = 8e-07
Identities = 67/228 (29%), Positives = 101/228 (43%), Gaps = 26/228 (11%)
Query: 687 KYSTCQSNSKSEEEVSMAGRVIATRNIGR-VNFYKILDDGEIIQIVIIANNAEDGKTNLK 511
K+ S++EV RV TR G + F + +IQ ++ AN N+
Sbjct: 95 KFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMV 154
Query: 510 EMVKNIKRGDIVGFTGY------PGKTKT-DELSIFVDDIIILSPCLRTLPVEHFGLKDT 352
+ ++ IV G P K+ T L I + I +S LP+ L+D
Sbjct: 155 KWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPIL---LEDA 211
Query: 351 EXXXXXXXXXXX--LNMESR------------NRFITRSK--VINYLRNFLIQKEFIEVE 220
+N+++R N+ I R + V R +L K+F EV
Sbjct: 212 SRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVH 271
Query: 219 TPILNNIPGGAAAKPF-ITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEG 43
TP L P + F +T+ K YL SP+ ++LIV RV+EIG FR E
Sbjct: 272 TPKLLGAPSEGGSSVFEVTY---FKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAEN 328
Query: 42 IDL-THNPEFTSCE 4
+ H EFT +
Sbjct: 329 SNTHRHMTEFTGLD 342
>gi|3947886 (AF001831) pyruvate oxidase [Salmonella typhimurium]
Length = 325
Score = 54.3 bits (128), Expect = 1e-06
Identities = 32/96 (33%), Positives = 52/96 (53%), Gaps = 5/96 (5%)
Query: 288 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 124
+ R+ ++ +R F + +EVETP ++ +I F+ + N YL S
Sbjct: 17 LKRAAIMAEIRRFFGDRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINLYLMTS 76
Query: 123 PELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
PE + K+L+ G VF++ + FRNE + HNPEFT E+
Sbjct: 77 PEYHMKRLLEAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEW 117
>gi|3298338|dbj|BAA31457| (AB010464) aspartyl tRNA synthetase [Haloferax volcanii]
Length = 433
Score = 54.3 bits (128), Expect = 1e-06
Identities = 55/226 (24%), Positives = 99/226 (43%), Gaps = 6/226 (2%)
Query: 678 TCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVK 499
T ++++ + V++AG V R++G + F + D IQ+ + +D +L E
Sbjct: 5 TYTADAEPGDTVTVAGWVHEVRDLGGIAFLILRDTSGKIQVKFEKDEMDD---DLVETGL 61
Query: 498 NIKRGDIVGFTGYPGKTKTDELSIFV--DDIIILSPCLRTLPVEHFGLKDTEXXXXXXXX 325
+ R ++ TG + + V + + +++ LP++ G D E
Sbjct: 62 GVHRESVISVTGEVDEEPRAPTGVEVTPESLDVIAEAEAQLPLDPSGKVDAELSTRLDNR 121
Query: 324 XXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNE 154
L E + F R++V +R+ E+ TP + GG P F E
Sbjct: 122 TLDLRKDEVKAIFEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQE 181
Query: 153 LKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDL-THNPEFTSCEF 1
++ SP+L+ + ++ GL RVFE+G FR E + H E TS +F
Sbjct: 182 A----FMNQSPQLFKQLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDF 229
>gi|3860712|emb|CAA14613| (AJ235270) ASPARAGINYL-TRNA SYNTHETASE (aspS) [Rickettsia
prowazekii]
Length = 605
Score = 53.5 bits (126), Expect = 2e-06
Identities = 61/222 (27%), Positives = 98/222 (43%), Gaps = 11/222 (4%)
Query: 687 KYSTCQSN----SKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAE---D 529
KY T N S +EV ++G V R+ G + F + D I QIV N + D
Sbjct: 3 KYRTHNCNELQLSNVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQNQQLMYD 62
Query: 528 GKTNLKEMVKNIKRGDIVG--FTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 355
E V + G +V K T + + + I+ S V + +
Sbjct: 63 ASRLCYESVITVS-GTVVARSLDTINNKLPTGYVEVLAMECIVESASSPLPFVINNEKEA 121
Query: 354 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAK 178
E + N I RS+VI ++R+ +I + F E++TPIL ++ P GA +
Sbjct: 122 PEESRLKHRFLDLRREKLHNNIILRSQVIAHIRHLMIARGFTELQTPILTSSSPEGA--R 179
Query: 177 PFITFHNELKSNFY-LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNP 22
F+ FY L +P+ + + L+V G +R F+I FR+E +P
Sbjct: 180 DFLVPSRIHPGKFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEDARADRSP 232
>gi|3618213|emb|CAA20876| (AL031579) ASPARTYL-TRNA SYNTHETASE [Schizosaccharomyces pombe]
Length = 580
Score = 52.3 bits (123), Expect = 4e-06
Identities = 63/216 (29%), Positives = 102/216 (47%), Gaps = 34/216 (15%)
Query: 651 EEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVK---NIKRG 484
+ V + RV +R G ++ F+ + + IQ + + N T K+MVK +I
Sbjct: 105 QTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNK----DTISKQMVKWCGSISLE 160
Query: 483 DIVGFTGYPGKTK-------TDELSIFVDDIIILSPCLRTLP--VEHFGLKDT------E 349
IV G K+ + I + I ++SP + LP VE G + E
Sbjct: 161 SIVLVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAGRSEEQIRESEE 220
Query: 348 XXXXXXXXXXXLNMESR--NR------------FITRSKVINYLRNFLIQKEFIEVETPI 211
+N+++R NR F ++ + R FL+ F E+ TP
Sbjct: 221 NAAEGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNEIHTPK 280
Query: 210 LNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNEGID-L 34
++ + F + K++ +L SP+LY + LI RVFEIG FR E +
Sbjct: 281 MSGASSEGGSNVFKIQY--FKTDGFLSQSPQLYKQMLIAADRERVFEIGPVFRAEDSNTY 338
Query: 33 THNPEFTSCE 4
H EFT +
Sbjct: 339 RHMTEFTGLD 348
>gi|1127124|pdb|1KRT| Mol_id: 1; Molecule: Lysyl-Trna Synthetase (Product Of Lyss Gene);
Chain: Null; Domain: Anticodon-Binding Domain (Residues
40 - 149); Ec: 6.1.1.6; Engineered: Yes
>gi|1127125|pdb|1KRS| Mol_id: 1; Molecule: Lysyl-Trna
Synthetase (Product Of Lyss Gene); Chain: Null; Domain:
Anticodon-Binding Domain (Residues 40 - 149); Ec:
6.1.1.6; Engineered: Yes
Length = 120
Score = 51.9 bits (122), Expect = 5e-06
Identities = 35/112 (31%), Positives = 63/112 (56%), Gaps = 3/112 (2%)
Query: 735 YPHKFHVKNTIKEIKSKYSTCQSNSKSEE---EVSMAGRVIATRNIGRVNFYKILDDGEI 565
+P+ F +T ++ +++ + N + E EV++AGR++ R +G+ +F + D G
Sbjct: 7 FPNDFRRDHTSDQLHAEFDG-KENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGR 65
Query: 564 IQIVIIANNAEDGKTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILS 400
IQ+ + ++ +G N E K GDI+G G KTKT ELSI ++ +L+
Sbjct: 66 IQLYVARDDLPEGVYN--EQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLT 118
>gi|3845470|emb|CAA19270| (AL023705) hypothetical protein [Schizosaccharomyces pombe]
Length = 611
Score = 51.2 bits (120), Expect = 9e-06
Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 282 RSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 109
RS++ + +F +EF EVETP+L + P GA + F+ FY L SP+ Y
Sbjct: 162 RSRLAYQVHSFFNDREFCEVETPLLFKSTPEGA--REFVVPSRLNPGKFYALPQSPQQYK 219
Query: 108 KKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L+ G+ ++I + FR+E + PEFT +
Sbjct: 220 QILMASGIGNYYQIARCFRDEDLRFDRQPEFTQID 254
>gi|4557513|oth|NP_001340|PDARS aspartyl-tRNA synthetase >gi|135098|sp|P14868|SYD_HUMAN
ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|68530|pir||SYHUDT aspartate--tRNA ligase (EC
6.1.1.12) - human >gi|179102 (J05032) aspartyl-tRNA
synthetase [Homo sapiens]
Length = 500
Score = 51.2 bits (120), Expect = 9e-06
Identities = 56/205 (27%), Positives = 90/205 (43%), Gaps = 23/205 (11%)
Query: 660 KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVK---NIK 490
K++E V + RV +R G+ F + +Q ++ G K+MVK NI
Sbjct: 54 KADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAV-----GDHASKQMVKFAANIN 108
Query: 489 RGDIVGFTGYP-------GKTKTDELSIFVDDIIILSPCLRTLPV--------EHFGLKD 355
+ IV G G ++ + V I ++S LP+ E G ++
Sbjct: 109 KESIVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEQEGEEE 168
Query: 354 TEXXXXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETPILNNIPGG 190
++ R F +S + + R LI K F+E++TP + +
Sbjct: 169 GRATVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASE 228
Query: 189 AAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNE 46
A F + K+N YL SP+LY + I +VF IG FR E
Sbjct: 229 GGANVFTVSY--FKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAE 274
>gi|549025|sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS) (ANTIGEN
T5) >gi|541455|pir||S42047 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium leprae
>gi|581332|emb|CAA54735| (X77655) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3136016|emb|CAA19094| (AL023591) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3335328|gb||S82268_1 (S82268) aspartyl-tRNA
synthetase [Mycobacterium leprae]
Length = 589
Score = 50.8 bits (119), Expect = 1e-05
Identities = 33/93 (35%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
Query: 282 RSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 109
RSKV R L + +F+E+ETP I + P GA + F+ FY L SP+L+
Sbjct: 140 RSKVNATARAVLARHDFVEIETPTITRSTPEGA--RDFLVPARLRPGTFYALPQSPQLFK 197
Query: 108 KKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L+V G+ R ++I +R+E PEFT +
Sbjct: 198 QLLMVAGMERYYQIAHCYRDEDFRADRQPEFTQLD 232
>gi|2500969|sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1478240|emb|CAB01271| (Z77724) aspS [Mycobacterium
tuberculosis]
Length = 596
Score = 50.8 bits (119), Expect = 1e-05
Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 282 RSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 109
RS+V R L + +F+E+ETP I + P GA + F+ +FY L SP+L+
Sbjct: 145 RSRVNAAARAVLARHDFVEIETPTITRSTPEGA--RDFLVPARLHPGSFYALPQSPQLFK 202
Query: 108 KKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ L+V G+ R ++I + +R+E PEFT +
Sbjct: 203 QLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLD 237
>gi|135099|sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68531|pir||SYRTDT aspartate--tRNA ligase (EC
6.1.1.12) - rat >gi|203066 (J04487) aspartyl-tRNA
synthetase [Rattus norvegicus] >gi|1773257 (U30812)
aspartyl-tRNA synthetase [Rattus norvegicus]
Length = 501
Score = 50.8 bits (119), Expect = 1e-05
Identities = 57/205 (27%), Positives = 90/205 (43%), Gaps = 23/205 (11%)
Query: 660 KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVK---NIK 490
K++E V + RV +R G+ F + +Q ++ G K+MVK NI
Sbjct: 55 KADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAV-----GDHASKQMVKFAANIN 109
Query: 489 RGDIVGFTGYP-------GKTKTDELSIFVDDIIILSPCLRTLPV--------EHFGLKD 355
+ I+ G G ++ + V I ++S LP+ E G +D
Sbjct: 110 KESIIDVEGIVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEED 169
Query: 354 TEXXXXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETPILNNIPGG 190
++ R F +S + + R LI K F+E++TP + +
Sbjct: 170 GRATVNQDTRLDNRIIDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAASE 229
Query: 189 AAAKPFITFHNELKSNFYLRVSPELYHKKLIVGGLNRVFEIGKQFRNE 46
A F + KSN YL SP+LY + I +VF IG FR E
Sbjct: 230 GGANVFTVSY--FKSNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAE 275
>gi|3323370 (AE001271) lysyl-tRNA synthetase (lysS-2) [Treponema pallidum]
Length = 351
Score = 48.8 bits (114), Expect = 5e-05
Identities = 31/94 (32%), Positives = 51/94 (53%), Gaps = 7/94 (7%)
Query: 282 RSKVINYLRNFLIQKEFIEVETPILNN--IPGGAA----AKPFITFHNELKSNFYLRVSP 121
R++ + +R+F ++ +IE++TP L +P + F + H + YL SP
Sbjct: 9 RAQCLRAVRDFFLEHHYIELDTPALARALVPERCLEVFQTEYFTSVHAKDTQKLYLVPSP 68
Query: 120 ELYHKKLIVGGLNRVFEIGKQFRN-EGIDLTHNPEFTSCEF 1
E++ K LI F+I K +RN E + H PEFT E+
Sbjct: 69 EVFLKPLIAQLQRSAFQISKCYRNGESMGALHRPEFTMVEY 109
>gi|1169858|sp|P43151|GBA_LEIDO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT >gi|556256
(L36832) G protein alpha subunit [Leishmania donovani]
Length = 464
Score = 41.0 bits (94), Expect = 0.011
Identities = 24/70 (34%), Positives = 40/70 (56%), Gaps = 12/70 (17%)
Query: 570 EIIQIVIIANNAEDGKTNLKEMVKNIKRGD------------IVGFTGYPGKTKTDELSI 427
E +Q++ + D ++ E+ +KRGD I+G G P +K+ E S+
Sbjct: 12 ETVQVISALTDYID-QSKFAEIHSKLKRGDGPGESGKSTIFQIIGIAGRPSLSKSSEFSL 70
Query: 426 FVDDIIILSPCLRTLPVEHFGL 361
+I +LS C LP ++FGL
Sbjct: 71 KATEITLLSTCYHMLPDDYFGL 92
>gi|2983331 (AE000706) lysyl-tRNA synthetase (genX) homolog [Aquifex aeolicus]
Length = 293
Score = 40.2 bits (92), Expect = 0.018
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 4/90 (4%)
Query: 270 INYLRNFLIQKEFIEVETPILNNIPGGAA----AKPFITFHNELKSNFYLRVSPELYHKK 103
IN +R F +K + EV TP+L + P + K + E K +L SPE KK
Sbjct: 11 INEVRKFFKEKGYTEVSTPLLLDFPNLDSNVEPVKVEVLERGENKVK-WLHTSPEYSMKK 69
Query: 102 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 1
L+ +F+I K FRN H EF E+
Sbjct: 70 LLSRYKRDIFQITKVFRNNEWGRLHRIEFHMLEW 103
>gi|3122881|sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 324
Score = 39.9 bits (91), Expect = 0.024
Identities = 30/97 (30%), Positives = 46/97 (46%), Gaps = 3/97 (3%)
Query: 291 FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNELKSNFYLRVSPE 118
F R++V +R+ E+ TP + GG P F E ++ SP+
Sbjct: 25 FEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQEA----FMNQSPQ 80
Query: 117 LYHKKLIVGGLNRVFEIGKQFRNEGIDL-THNPEFTSCEF 1
L+ + ++ GL RVFE+G FR E + H E TS +F
Sbjct: 81 LFKQLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDF 120
>gi|3549678|emb|CAA20589| (AL031394) putative aspartate--tRNA ligase [Arabidopsis thaliana]
Length = 636
Score = 37.9 bits (86), Expect = 0.091
Identities = 35/150 (23%), Positives = 60/150 (39%), Gaps = 7/150 (4%)
Query: 453 KTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT-----EXXXXXXXXXXXLNMESRNRF 289
K KT + + + + IL+P LP + E + +N
Sbjct: 160 KMKTGFVEVVAEHVEILNPVRTKLPFLVTTADENKDLIKEEIRLRFRCLDLRRQQMKNNI 219
Query: 288 ITRSKVINYLRNFLIQKE-FIEVETPILNNIPGGAAAKPFITFHNELKSNFY-LRVSPEL 115
+ R V+ +R +L + FIE T FY L SP+L
Sbjct: 220 VLRHNVVKLIRRYLEDRHGFIESGT-------------------------FYALPQSPQL 254
Query: 114 YHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 4
+ + L+V G ++ ++I + FR+E + PEFT +
Sbjct: 255 FKQMLMVSGFDKYYQIARCFRDEDLRADRQPEFTQLD 291
>gi|4127381|emb|CAA09487| (AJ011104) elongation factor G [Apple proliferation phytoplasma]
Length = 688
Score = 34.8 bits (78), Expect = 0.79
Identities = 26/91 (28%), Positives = 45/91 (48%), Gaps = 10/91 (10%)
Query: 672 QSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGK---------- 523
+ S +E ++A +V+ +G++ F+++ G I + N + K
Sbjct: 299 RKTSDNEPFTALAFKVMTDPYVGKLTFFRVYA-GTIKTGSYVTNATKQVKERLGRLLQMH 357
Query: 522 TNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILS 400
N +E +K + GDIV G T D L+ DDII+ S
Sbjct: 358 ANSREEIKEVYAGDIVAAVGLKNTTPGDTLTSINDDIILES 398
>gi|3377724 (AF079365) silent surface layer protein [Lactobacillus crispatus]
Length = 452
Score = 34.8 bits (78), Expect = 0.79
Identities = 16/56 (28%), Positives = 30/56 (53%)
Query: 678 TCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLK 511
T ++N+ + ++T+ IG NFY+++ DG+ + I A+N + K LK
Sbjct: 341 TTRANNDKAKRYESVTVAMSTKKIGDKNFYEVIKDGKATSMYINADNIDGTKRTLK 396
>gi|2500990|sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENYLALANINE--TRNA LIGASE)
>gi|2129182|pir||G64360 phenylalanine--tRNA ligase (EC
6.1.1.20) alpha chain - Methanococcus jannaschii
>gi|1592293 (U67499) phenylalanyl-tRNA synthetase,
subunit alpha (pheS) [Methanococcus jannaschii]
Length = 480
Score = 34.4 bits (77), Expect = 1.0
Identities = 15/27 (55%), Positives = 18/27 (66%)
Query: 84 NRVFEIGKQFRNEGIDLTHNPEFTSCE 4
++VF I + FRNE ID H PEF CE
Sbjct: 343 HKVFCIDRVFRNEAIDYKHLPEFYQCE 369
>gi|2650424 (AE001091) 2-isopropylmalate synthase (leuA-2) [Archaeoglobus
fulgidus]
Length = 503
Score = 34.0 bits (76), Expect = 1.4
Identities = 32/116 (27%), Positives = 55/116 (46%), Gaps = 11/116 (9%)
Query: 747 GKNVYPHK--FHVKNTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDD 574
G+N + H+ H +KE YST + + E V R++ ++ GR KIL++
Sbjct: 281 GENAFSHESGIHAHGVLKE----YSTFEPGVVTPEMVGHKRRIVIGKHAGRYQIKKILEE 336
Query: 573 GEIIQIVIIANNAEDGKTN-----LKEMVKNIKRGDIVGFTGYP----GKTKTDELSIFV 421
+ +D K N +KEM KR + G+ K +E +I V
Sbjct: 337 A--------GYHLDDEKLNQIFEKVKEMGDKGKRVTDLDLFAIAEVVIGELKREEKAILV 388
Query: 420 DDIIILS 400
D++ +L+
Sbjct: 389 DEVTVLT 395
>gi|2128703|pir||F64444 hypothetical protein MJ1159 - Methanococcus jannaschii >gi|1500014
(U67558) replication factor A related protein
[Methanococcus jannaschii]
Length = 645
Score = 32.8 bits (73), Expect = 3.1
Identities = 36/88 (40%), Positives = 48/88 (53%), Gaps = 11/88 (12%)
Query: 702 KEIKSKYSTCQSNSKSE--EEVSMAGRVIATRNIGRVNFYKILDDGEI--IQIVIIANNA 535
++I+S+ + +K E E VS+ GRVIA N V+ DGEI +Q +I+ N
Sbjct: 270 EKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDL-----DGEIAKVQDIILDNGT 324
Query: 534 ED-------GKTNLKEMVKNIKRGDIVGFTGYPGKTKTD 439
GKT L E NIK GD+V T KT D
Sbjct: 325 GRVRVSFWRGKTALLE---NIKEGDLVRITNCRVKTFYD 360
>gi|2305222 (AF012089) phenylalanyl tRNA synthetase [Drosophila melanogaster]
Length = 452
Score = 32.5 bits (72), Expect = 4.0
Identities = 15/40 (37%), Positives = 22/40 (54%)
Query: 135 LRVSPELYHKKLIVGGLNRVFEIGKQFRNEGIDLTHNPEF 16
LR + +LI GGL+ +G+ +R + ID TH P F
Sbjct: 137 LRAHTTAHQVELISGGLDNFLVVGEVYRRDEIDSTHYPVF 176
>gi|541344|pir||S42927 probable transport protein - Staphylococcus epidermidis
>gi|459262|emb|CAA83061| (Z30586) ABC transporter
(putative) [Staphylococcus epidermidis]
Length = 231
Score = 32.1 bits (71), Expect = 5.2
Identities = 15/35 (42%), Positives = 21/35 (59%)
Query: 525 KTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFV 421
KT LK++ N+KRG IVG G G KT + + +
Sbjct: 16 KTILKDISLNLKRGQIVGLVGANGAGKTSLMKVIL 50
>gi|1086133|pir||S42931 potential ABC transporter - Staphylococcus hominis
>gi|459265|emb|CAA83063| (Z30587) Potential ABC
transporter [Staphylococcus hominis]
Length = 231
Score = 32.1 bits (71), Expect = 5.2
Identities = 15/35 (42%), Positives = 21/35 (59%)
Query: 525 KTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFV 421
KT LK++ N+KRG IVG G G KT + + +
Sbjct: 16 KTILKDISLNLKRGQIVGLVGANGAGKTSLMKVIL 50
>gi|3758843|emb|CAB11128| (Z98551) predicted using hexExon; MAL3P6.23 (PFC0820w), Hypothetical
protein, len: 4982 aa [Plasmodium falciparum]
Length = 4981
Score = 31.3 bits (69), Expect = 9.0
Identities = 41/182 (22%), Positives = 80/182 (43%), Gaps = 9/182 (4%)
Query: 783 QRLESISNSLKQGKNVYPHKFHVKNTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIG 604
+++ +I NSL + N + + +K T+K +K C+ + SM
Sbjct: 3969 EQMLNILNSLFKNLNNTDNSYTIKETLKCLKE---LCKYDGDRWPSSSMY---------- 4015
Query: 603 RVNFYKILDDGEIIQIVIIANNAEDGKTNLK---EMVKNIKRGDIVGFTGYPGKTKTDEL 433
++F KIL D +IIQI + ++ + K E+ + ++R K KT ++
Sbjct: 4016 -LSFQKILSDNKIIQIYLNSDEVMNRVYICKIMCELYRTLRR----------EKDKTKDM 4064
Query: 432 SIFVDDIIIL----SPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRS--KV 271
+ ++D II+ + C + + +++ M +NR I +S +
Sbjct: 4065 GVILNDDIIIDGEGNKCGDIINSDILKIEEENKKKERRKTKKEKEMRGKNRKIKKSFYET 4124
Query: 270 INYLRNFLIQK 238
I YL L+ K
Sbjct: 4125 ITYLFIHLMDK 4135
>gi|2833489|sp|Q57242|UUP1_HAEIN ABC TRANSPORTER ATP-BINDING PROTEIN UUP-1 >gi|1074724|pir||E64170
hypothetical protein HI1300 - Haemophilus influenzae
(strain Rd KW20) >gi|1574757 (U32809) ABC transporter,
ATP-binding protein [Haemophilus influenzae Rd]
Length = 647
Score = 31.3 bits (69), Expect = 9.0
Identities = 37/129 (28%), Positives = 66/129 (50%), Gaps = 29/129 (22%)
Query: 798 DAFYLQRLESISNSLKQGKNV-YPHKFHVKNTIKEIKSKYSTCQSN----SKSEEEVSMA 634
D +++++ + L +G+ V YP + + T KE + Q+ ++EEV +
Sbjct: 212 DRSFIRKMATRIVDLDRGQLVSYPGNYDLYLTTKEENLRVEALQNELFDKRLAQEEVWIR 271
Query: 633 GRVIA--TRNIGRVNFYKILDD----------------------GEIIQIVIIANNAEDG 526
+ A TRN GRV K++ + G+I+ + + G
Sbjct: 272 QGIKARRTRNEGRVRALKVMREERRQRRDVMGTAKLQLDTSSRSGKIVFEMEDVSYEIAG 331
Query: 525 KTNLKEMVKNIKRGDIVGFTGYPGKTKTDELSIFVDDI 412
KT LK+ I RGD + G G KT + + + +I
Sbjct: 332 KTLLKDFSTTILRGDKIALVGPNGCGKTTFIKLLLGEI 369
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 17, 1999 5:33 AM
Number of letters in database: 113,023,754
Number of sequences in database: 369,800
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 134006404
Number of Sequences: 369800
Number of extensions: 2402067
Number of successful extensions: 6542
Number of sequences better than 10.0: 202
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 6365
Number of HSP's gapped (non-prelim): 108
length of query: 283
length of database: 113023754
effective HSP length: 54
effective length of query: 228
effective length of database: 93054554
effective search space: 21216438312
effective search space used: 21216438312
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 69 (31.3 bits)