BLASTX 2.0.8 [Jan-05-1999]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 11VII22F
         (759 letters)

Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
           369,800 sequences; 113,023,754 total letters

Searching..................................................done

                                                                   Score     E
Sequences producing significant alignments:                        (bits)  Value

gi|2291181 (AF016421) strong similarity to peptidase family M16 ...    38  0.079
gi|1730966|sp|Q10040|YQA4_CAEEL HYPOTHETICAL 85.5 KD ZINC PROTEA...    38  0.10
gi|1280107 (U55372) strong similarity to insulin-degrading enzym...    33  2.0
gi|3881283|emb|CAB16537| (Z99283) predicted using Genefinder [Ca...    31  7.8


>gi|2291181 (AF016421) strong similarity to peptidase family M16 or the
            insulinase family [Caenorhabditis elegans]
            Length = 1067
            
 Score = 37.9 bits (86), Expect = 0.079
 Identities = 19/59 (32%), Positives = 33/59 (55%)

Query: 427  QLSEDIFYNQLRTNECYGYIVGCNNIMIDGNIFISFKVVGDRDVNDICNRIIKYIEELK 251
            QL  +  +N LRTNE  GYIV   + +  G + ++  V G + V+ +  RI  ++E ++
Sbjct: 855  QLIREPAFNTLRTNEALGYIVWTGSRLNCGTVALNVIVQGPKSVDHVLERIEVFLESVR 913



>gi|1730966|sp|Q10040|YQA4_CAEEL HYPOTHETICAL 85.5 KD ZINC PROTEASE C28F5.4 >gi|726434 (U23180)
           similar to insulinase [Caenorhabditis elegans]
           Length = 745
           
 Score = 37.5 bits (85), Expect = 0.10
 Identities = 19/63 (30%), Positives = 32/63 (50%)

Query: 439 KFYLQLSEDIFYNQLRTNECYGYIVGCNNIMIDGNIFISFKVVGDRDVNDICNRIIKYIE 260
           K   +L ++  Y  LRTNE  GY V   + + DGN+++   V G    + +  RI  ++E
Sbjct: 599 KLLNELIKNPAYTILRTNEALGYNVSTESRLNDGNVYLHVIVQGPESADHVLERIEVFLE 658

Query: 259 ELK 251
             +
Sbjct: 659 SAR 661



>gi|1280107 (U55372) strong similarity to insulin-degrading enzymes
           (insulinase) [Caenorhabditis elegans]
           Length = 980
           
 Score = 33.2 bits (74), Expect = 2.0
 Identities = 18/59 (30%), Positives = 32/59 (53%)

Query: 427 QLSEDIFYNQLRTNECYGYIVGCNNIMIDGNIFISFKVVGDRDVNDICNRIIKYIEELK 251
           QL ++  ++ LRTNE  GYIV        G + ++  V G + V+ +  RI  ++E ++
Sbjct: 769 QLIKEPVFDTLRTNEALGYIVWTGCRFNCGAVALNIFVQGPKSVDYVLERIEVFLESVR 827



>gi|3881283|emb|CAB16537| (Z99283) predicted using Genefinder [Caenorhabditis elegans]
           Length = 301
           
 Score = 31.3 bits (69), Expect = 7.8
 Identities = 15/52 (28%), Positives = 26/52 (49%)

Query: 406 YNQLRTNECYGYIVGCNNIMIDGNIFISFKVVGDRDVNDICNRIIKYIEELK 251
           ++ LRT E  GYIV        G + +   V G + V+ +  RI  ++E ++
Sbjct: 103 FDTLRTKESLGYIVWTRTHFNCGTVALQILVQGPKSVDHVLERIEAFLESVR 154


  Database: Non-redundant GenBank CDS
  translations+PDB+SwissProt+SPupdate+PIR
    Posted date:  Apr 17, 1999  5:33 AM
  Number of letters in database: 113,023,754
  Number of sequences in database:  369,800
  
Lambda     K      H
   0.318    0.135     0.00 

Gapped
Lambda     K      H
   0.270   0.0470 4.94e-324 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58831832
Number of Sequences: 369800
Number of extensions: 738434
Number of successful extensions: 2381
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2375
Number of HSP's gapped (non-prelim): 6
length of query: 253
length of database: 113023754
effective HSP length: 54
effective length of query: 198
effective length of database: 93054554
effective search space: 18424801692
effective search space used: 18424801692
frameshift window, decay const: 50,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 68 (30.9 bits)