BLASTX 2.0.8 [Jan-05-1999]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= 12VII-12F
(719 letters)
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
369,800 sequences; 113,023,754 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|3864|emb|CAA39699| (X56259) lysine--tRNA ligase [Saccharomyce... 226 2e-58
gi|2501024|sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (L... 224 7e-58
gi|505108|dbj|BAA06688| (D31890) similar to lysyl tRNA synthetas... 224 7e-58
gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE, CYTOPLASMI... 224 7e-58
gi|2366752|dbj|BAA22084| (D32053) Lysyl tRNA Synthetase [Homo sa... 224 7e-58
gi|2501023|sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 224 7e-58
gi|586059|sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 222 2e-57
gi|4325324|gb|AAD17333| (AF125574) lysyl-tRNA synthetase; LysRS ... 206 1e-52
gi|2501025|sp|Q43776|SYK_LYCES LYSYL-TRNA SYNTHETASE (LYSINE--TR... 199 2e-50
gi|1174526|sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 186 2e-46
gi|135135|sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TR... 183 1e-45
gi|68526|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6) - Escheric... 183 1e-45
gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna Synthetase (Lysu) (E.C... 180 1e-44
gi|68527|pir||SYECKU lysine--tRNA ligase (EC 6.1.1.6), thermoind... 180 1e-44
gi|464826|sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUC... 180 1e-44
gi|730872|sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 177 8e-44
gi|730871|sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 172 2e-42
gi|2961644 (AF052056) lysyl-tRNA synthetase [Campylobacter jejuni] 172 2e-42
gi|2983651 (AE000728) lysyl-tRNA synthetase [Aquifex aeolicus] 172 3e-42
gi|2501020|sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TR... 171 5e-42
gi|2501017|sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TR... 169 2e-41
gi|586058|sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRN... 168 3e-41
gi|4154685 (AE001455) LYSYL-TRNA SYNTHETASE [Helicobacter pylori... 167 7e-41
gi|2127598|pir||S69892 probable lysyl-tRNA synthetase - Mycoplas... 166 2e-40
gi|3329245 (AE001350) Lysyl tRNA Synthetase [Chlamydia trachomatis] 164 4e-40
gi|1174528|sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TR... 162 2e-39
gi|4377254|gb|AAD19069| (AE001673) Lysyl tRNA Synthetase [Chlamy... 161 5e-39
gi|2501021|sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TR... 160 9e-39
gi|3582260 (M27221) lysyl-tRNA synthetase [Sinorhizobium meliloti] 160 9e-39
gi|1351162|sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TR... 158 3e-38
gi|1838991|emb|CAB06635| (Z85982) lysX [Mycobacterium tuberculosis] 157 7e-38
gi|146689 (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [... 157 1e-37
gi|2501016|sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TR... 157 1e-37
gi|2501018|sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TR... 154 5e-37
gi|2501019|sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TR... 152 3e-36
gi|2501022|sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TR... 147 8e-35
gi|3122897|sp|O06284|SYK_MYCTU LYSYL-TRNA SYNTHETASE (LYSINE--TR... 143 2e-33
gi|3766370|emb|CAA21422| (AL031907) lysyl-trna synthetase [Schiz... 140 8e-33
gi|1351160|sp|P32048|SYKM_YEAST LYSYL-TRNA SYNTHETASE, MITOCHOND... 118 3e-26
gi|450763|emb|CAA40634| (X57360) lysine--tRNA ligase [Saccharomy... 105 3e-22
gi|3915067|sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTA... 76 3e-13
gi|4155111 (AE001489) ASPARTYL-TRNA SYNTHETASE [Helicobacter pyl... 73 3e-12
gi|3024680|sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTA... 72 4e-12
gi|2500967|sp|Q48979|SYD_MYCCA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 69 2e-11
gi|1174503|sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTA... 66 2e-10
gi|4378708|gb|AAD19636| (AF108665) lysyl-tRNA synthetase homolog... 66 3e-10
gi|2500973|sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTA... 64 8e-10
gi|4388836|pdb|1B8A|A Chain A, Aspartyl Trna Synthetase From Pyr... 64 8e-10
gi|1174524|sp|P43826|SYK3_HAEIN HYPOTHETICAL LYSYL-TRNA SYNTHETA... 64 1e-09
gi|1074996|pir||I64097 lysyl-tRNA synthetase analog (genX) homol... 64 1e-09
gi|2500971|sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTA... 63 2e-09
gi|3915063|sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 63 2e-09
gi|3328981 (AE001325) Aspartyl tRNA Synthetase [Chlamydia tracho... 62 3e-09
gi|135102|sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 62 5e-09
gi|3915068|sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTA... 61 9e-09
gi|3122880|sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 59 3e-08
gi|4101633 (AF005272) lysyl-tRNA synthetase homolog [Haemophilus... 59 3e-08
gi|3323310 (AE001266) aspartyl-tRNA synthetase (aspS) [Treponema... 59 3e-08
gi|3122885|sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 59 3e-08
gi|4376961|gb|AAD18801| (AE001648) Aspartyl tRNA Synthetase [Chl... 58 6e-08
gi|2500972|sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTA... 58 8e-08
gi|3257434|dbj|BAA30117| (AP000004) 438aa long hypothetical aspa... 58 8e-08
gi|2500968|sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTA... 57 1e-07
gi|549026|sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 57 1e-07
gi|3875743|emb|CAB04081| (Z81497) similar to aspartyl-tRNA synth... 57 2e-07
gi|3122882|sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTA... 56 3e-07
gi|135101|sp|P15179|SYDM_YEAST ASPARTYL-TRNA SYNTHETASE, MITOCHO... 55 4e-07
gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 55 4e-07
gi|1351148|sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTA... 55 5e-07
gi|135100|sp|P04802|SYDC_YEAST ASPARTYL-TRNA SYNTHETASE, CYTOPLA... 54 9e-07
gi|1064982|pdb|1ASY|A Saccharomyces cerevisiae >gi|1064984|pdb|1... 54 9e-07
gi|135138|sp|P03812|SYK3_ECOLI HYPOTHETICAL LYSYL-TRNA SYNTHETAS... 54 1e-06
gi|1361210|pir||S56383 lysyl-tRNA synthetase homolog protein gen... 54 1e-06
gi|3298338|dbj|BAA31457| (AB010464) aspartyl tRNA synthetase [Ha... 54 1e-06
gi|3860712|emb|CAA14613| (AJ235270) ASPARAGINYL-TRNA SYNTHETASE ... 53 2e-06
gi|4455210|emb|CAB36533| (AL035440) putative aspartate-tRNA liga... 53 2e-06
gi|78609|pir||A04437 hypothetical protein F-162 - Escherichia co... 53 3e-06
gi|551785 (J01611) gene x protein (putative); putative [Escheric... 53 3e-06
gi|3947886 (AF001831) pyruvate oxidase [Salmonella typhimurium] 52 4e-06
gi|3845470|emb|CAA19270| (AL023705) hypothetical protein [Schizo... 50 1e-05
gi|2500969|sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTA... 50 2e-05
gi|549025|sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTAT... 50 2e-05
gi|3618213|emb|CAA20876| (AL031579) ASPARTYL-TRNA SYNTHETASE [Sc... 50 2e-05
gi|4557513|oth|NP_001340|PDARS aspartyl-tRNA synthetase >gi|1350... 50 2e-05
gi|135099|sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE-... 49 3e-05
gi|1127124|pdb|1KRT| Mol_id: 1; Molecule: Lysyl-Trna Synthetas... 48 9e-05
gi|3323370 (AE001271) lysyl-tRNA synthetase (lysS-2) [Treponema ... 46 2e-04
gi|1169858|sp|P43151|GBA_LEIDO GUANINE NUCLEOTIDE-BINDING PROTEI... 41 0.009
gi|3122881|sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTA... 39 0.033
gi|2983331 (AE000706) lysyl-tRNA synthetase (genX) homolog [Aqui... 38 0.075
gi|3549678|emb|CAA20589| (AL031394) putative aspartate--tRNA lig... 37 0.13
gi|3377724 (AF079365) silent surface layer protein [Lactobacillu... 35 0.65
gi|2500990|sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHE... 34 0.85
gi|2305222 (AF012089) phenylalanyl tRNA synthetase [Drosophila m... 33 2.5
gi|2128703|pir||F64444 hypothetical protein MJ1159 - Methanococc... 33 2.5
gi|541344|pir||S42927 probable transport protein - Staphylococcu... 32 3.3
gi|1086133|pir||S42931 potential ABC transporter - Staphylococcu... 32 3.3
gi|4127381|emb|CAA09487| (AJ011104) elongation factor G [Apple p... 32 3.3
>gi|3864|emb|CAA39699| (X56259) lysine--tRNA ligase [Saccharomyces cerevisiae]
Length = 591
Score = 226 bits (569), Expect = 2e-58
Identities = 113/218 (51%), Positives = 158/218 (71%), Gaps = 6/218 (2%)
Query: 655 EEEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDI 479
EE+VS+AGR+ A R G ++ FY + DG +Q++ + D ++ K+ +KRGDI
Sbjct: 121 EEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYHDPESYEKDHDL-LKRGDI 179
Query: 478 VGFTGYPGKTKTD-----ELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXL 314
VG GY G+T+ E+S+FV + +L+PCL LP +HFG KD E +
Sbjct: 180 VGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGFKDQETRYRKRYLDLIM 239
Query: 313 NMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYL 134
N ++RNRFITRS++I Y+R FL Q++FIEVETP++N I GGA AKPFIT HN+L + Y+
Sbjct: 240 NKDARNRFITRSEIIRYIRKFLDQRKFIEVETPMMNVIAGGATAKPFITHHNDLDMDMYM 299
Query: 133 RVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
R++PEL+ +L+VGGL+RV+EIG+QFRNEGID+THNPEFT+CEF
Sbjct: 300 RIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEF 343
>gi|2501024|sp|Q22099|SYK_CAEEL PROBABLE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1086773 (U41105) coded for by C. elegans cDNA
yk124d11.3; coded for by C. elegans cDNA yk48a4.3; coded
for by C. elegans cDNA yk124d11.5; coded for by C.
elegans cDNA cm7h5; coded for by C. elegans cDNA cm7a10;
similar to class II aminoacyl-tRNA sy...
Length = 572
Score = 224 bits (564), Expect = 7e-58
Identities = 116/236 (49%), Positives = 155/236 (65%), Gaps = 1/236 (0%)
Query: 709 TIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAE 533
++ + +KY+ + EE VS+AGR+ + R G ++ FY I +G IQI+ A
Sbjct: 84 SLTDFITKYTPLEKEQVVEEIVSVAGRIHSKRESGSKLVFYDIHGEGTHIQIMANAK-FH 142
Query: 532 DGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT 353
G + + IKRGDIVGFTG +TK ELS+ ++I+ L+PCL LP HFGLKD
Sbjct: 143 TGDVDFVTLHDRIKRGDIVGFTGRATRTKAGELSLIPNEILQLTPCLHMLPHSHFGLKDK 202
Query: 352 EXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPF 173
E LN ++ F+ RSK+I +LR +L F+EVETPI+N I GGA AKPF
Sbjct: 203 ELRFRKRYLDLILNPRVKDNFVIRSKIITFLRRYLDNLGFLEVETPIMNQIAGGATAKPF 262
Query: 172 ITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
IT HN+L N +LRV+PELYH L+VGG++RV+E+G+ FRNEGIDLTHNPEFT+CEF
Sbjct: 263 ITHHNDLDMNLFLRVAPELYHKMLVVGGIDRVYEVGRLFRNEGIDLTHNPEFTTCEF 319
>gi|505108|dbj|BAA06688| (D31890) similar to lysyl tRNA synthetase. [Homo sapiens]
Length = 601
Score = 224 bits (564), Expect = 7e-58
Identities = 115/236 (48%), Positives = 160/236 (67%), Gaps = 2/236 (0%)
Query: 709 TIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNA 536
++ + KYS Q ++ + +AGR+ A R + G++ FY + +G +Q++ + N
Sbjct: 108 SLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNY 167
Query: 535 EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
+ + + + ++RGDI+G G PGKTK ELSI +I +LSPCL LP HFGLKD
Sbjct: 168 KSEEEFI-HINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKD 226
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKP 176
E LN R +FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKP
Sbjct: 227 KETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKP 286
Query: 175 FITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
FIT+HNEL N Y+R++PELYH L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 287 FITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 344
>gi|135139|sp|P15180|SYKC_YEAST LYSYL-TRNA SYNTHETASE, CYTOPLASMIC (LYSINE--TRNA LIGASE) (LYSRS)
>gi|68528|pir||SYBYKT lysine--tRNA ligase (EC 6.1.1.6) -
yeast (Saccharomyces cerevisiae) >gi|171799 (J04186)
lysyl-tRNA synthetase [Saccharomyces cerevisiae]
>gi|1122359|emb|CAA92376| (Z68196) Krs1p [Saccharomyces
cerevisiae] >gi|1431484|emb|CAA98863| (Z74333) ORF
YDR037w [Saccharomyces cerevisiae]
Length = 591
Score = 224 bits (564), Expect = 7e-58
Identities = 116/233 (49%), Positives = 163/233 (69%), Gaps = 7/233 (3%)
Query: 700 EIKSKYSTCQSNSK-SEEEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDG 527
E +KY+ + EE+VS+AGR+ A R G ++ FY + DG +Q++ + D
Sbjct: 105 EFLAKYAHLKKGETLPEEKVSIAGRIHAKRESGSKLKFYVLHGDGVEVQLMSQLQDYCDP 164
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKTKTD-----ELSIFVDDIIILSPCLRTLPVEHFGL 362
+ K+ +KRGDIVG GY G+T+ E+S+FV + +L+PCL LP +HFG
Sbjct: 165 DSYEKDHDL-LKRGDIVGVEGYVGRTQPKKGGEGEVSVFVSRVQLLTPCLHMLPADHFGF 223
Query: 361 KDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
KD E +N ++RNRFITRS++I Y+R FL Q++FIEVETP++N I GGA A
Sbjct: 224 KDQETRYRKRYLDLIMNKDARNRFITRSEIIRYIRRFLDQRKFIEVETPMMNVIAGGATA 283
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
KPFIT HN+L + Y+R++PEL+ +L+VGGL+RV+EIG+QFRNEGID+THNPEFT+CEF
Sbjct: 284 KPFITHHNDLDMDMYMRIAPELFLKQLVVGGLDRVYEIGRQFRNEGIDMTHNPEFTTCEF 343
>gi|2366752|dbj|BAA22084| (D32053) Lysyl tRNA Synthetase [Homo sapiens]
Length = 597
Score = 224 bits (564), Expect = 7e-58
Identities = 115/236 (48%), Positives = 160/236 (67%), Gaps = 2/236 (0%)
Query: 709 TIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNA 536
++ + KYS Q ++ + +AGR+ A R + G++ FY + +G +Q++ + N
Sbjct: 104 SLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNY 163
Query: 535 EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
+ + + + ++RGDI+G G PGKTK ELSI +I +LSPCL LP HFGLKD
Sbjct: 164 KSEEEFI-HINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKD 222
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKP 176
E LN R +FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKP
Sbjct: 223 KETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKP 282
Query: 175 FITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
FIT+HNEL N Y+R++PELYH L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 283 FITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|2501023|sp|Q15046|SYK_HUMAN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) (KIAA0070)
Length = 597
Score = 224 bits (564), Expect = 7e-58
Identities = 115/236 (48%), Positives = 160/236 (67%), Gaps = 2/236 (0%)
Query: 709 TIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNA 536
++ + KYS Q ++ + +AGR+ A R + G++ FY + +G +Q++ + N
Sbjct: 104 SLTDFIQKYSHLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNY 163
Query: 535 EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
+ + + + ++RGDI+G G PGKTK ELSI +I +LSPCL LP HFGLKD
Sbjct: 164 KSEEEFI-HINNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKD 222
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKP 176
E LN R +FI RSK+I Y+R+FL + F+E+ETP++N IPGGA AKP
Sbjct: 223 KETRYRQRYLDLILNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKP 282
Query: 175 FITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
FIT+HNEL N Y+R++PELYH L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 283 FITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|586059|sp|P37879|SYK_CRILO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|543180|pir||S43187 lysine--tRNA ligase (EC 6.1.1.6)
- long-tailed hamster >gi|469122|emb|CAA83505| (Z31711)
Lysyl tRNA Synthetase [Cricetulus longicaudatus]
Length = 597
Score = 222 bits (560), Expect = 2e-57
Identities = 113/236 (47%), Positives = 161/236 (67%), Gaps = 2/236 (0%)
Query: 709 TIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNA 536
++ + +YS Q ++ + +AGR+ A R + G++ FY + +G +Q++ + N
Sbjct: 104 SLTQFIQEYSQLQPGDHLTDITLKVAGRIHAKRASGGKLIFYDLRGEGVKLQVMANSRNY 163
Query: 535 EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
+ + ++ + ++RGDI+G G PGKTK ELSI +I +LSPCL LP HFGLKD
Sbjct: 164 KSEEEFVR-INNKLRRGDIIGVQGNPGKTKKGELSIIPYEITLLSPCLHMLPHLHFGLKD 222
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKP 176
E LN R +FI R+K+I Y+R+FL + F+E+ETP++N IPGGA AKP
Sbjct: 223 KETRYRQRYLDLILNDFVRQKFIVRAKIITYIRSFLDELGFLEIETPMMNIIPGGAVAKP 282
Query: 175 FITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
FIT+HNEL N Y+R++PELYH L+VGG++RV+EIG+QFRNEGIDLTHNPEFT+CEF
Sbjct: 283 FITYHNELDMNLYMRIAPELYHKMLVVGGIDRVYEIGRQFRNEGIDLTHNPEFTTCEF 340
>gi|4325324|gb|AAD17333| (AF125574) lysyl-tRNA synthetase; LysRS [Arabidopsis thaliana]
Length = 626
Score = 206 bits (519), Expect = 1e-52
Identities = 114/234 (48%), Positives = 154/234 (65%), Gaps = 22/234 (9%)
Query: 703 KEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDG 527
K I++ S + E S+AGR+++ R+ ++ FY + D +Q++ A+ +
Sbjct: 121 KYIETYGSLNNGDHVENAEESLAGRIMSKRSSSSKLFFYDLHGDDFKVQVMADASKSGLD 180
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLP----------- 380
+ ++ N KRGDIVG G+PGKTK ELSIF I+LS CL +P
Sbjct: 181 EAEFLKLHSNAKRGDIVGVIGFPGKTKRGELSIFPRSFILLSHCLHMMPRKADNVNAKKP 240
Query: 379 ----------VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFI 230
E + LKD E LN+E R F TR+K+I+Y+R FL K F+
Sbjct: 241 EIWVPGQTRNPEAYVLKDQESRYRQRHLDMILNVEVRQIFRTRAKIISYVRRFLDNKNFL 300
Query: 229 EVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRN 50
EVETP++N I GGAAA+PF+T HN+L Y+R++PELY +LIVGGL RV+EIGKQFRN
Sbjct: 301 EVETPMMNMIAGGAAARPFVTHHNDLDMRLYMRIAPELYLKQLIVGGLERVYEIGKQFRN 360
Query: 49 EGIDLTHNPEFTSCEF 2
EGIDLTHNPEFT+CEF
Sbjct: 361 EGIDLTHNPEFTTCEF 376
>gi|2501025|sp|Q43776|SYK_LYCES LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1147585|emb|CAA64223| (X94451) Lysyl-tRNA synthetase
[Lycopersicon esculentum]
Length = 588
Score = 199 bits (501), Expect = 2e-50
Identities = 109/235 (46%), Positives = 155/235 (65%), Gaps = 34/235 (14%)
Query: 709 TIKEIKSKYSTCQSNSKSEE-EVSMAGRVIATR-NIGRVNFYKILDDGEIIQIVIIANNA 536
+I E S+Y+ + E+ ++S+AGRVI+ R + ++ FY++L G +Q++ A ++
Sbjct: 85 SIPEFISRYAHLNTGEFPEDIDMSLAGRVISKRASSSKLYFYELLGGGARVQVLASARDS 144
Query: 535 EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLP-------- 380
+ +KRGDI+G GYPGK+K ELSIF I+L+PCL LP
Sbjct: 145 DVDAVQFSNYQSGVKRGDIIGVRGYPGKSKRGELSIFAKPFIVLAPCLHMLPRRLTSSIV 204
Query: 379 ------------------------VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKV 272
E + L+D E +N E R F TR+++
Sbjct: 205 DETRTQNFQGITAYDTWTPGDLRNPESYVLRDQETRYRQRYLDLMMNPEVRALFRTRARI 264
Query: 271 INYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHXKLIVG 92
I+Y+R+FL EF+EVETP +N GGA+A+PFIT HNEL + +RVSPELY KL+VG
Sbjct: 265 ISYIRSFLDNLEFLEVETPSMNLTAGGASARPFITHHNELDTELLIRVSPELYLKKLVVG 324
Query: 91 GLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
G +RV+E+GK FRNEG+DLTH+PEFT CE
Sbjct: 325 GFDRVYELGKHFRNEGMDLTHSPEFTMCE 353
>gi|1174526|sp|P43825|SYK_HAEIN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1074993|pir||D64110 lysine--tRNA ligase (EC 6.1.1.6)
- Haemophilus influenzae (strain Rd KW20) >gi|1574141
(U32800) lysyl-tRNA synthetase (lysU) [Haemophilus
influenzae Rd]
Length = 502
Score = 186 bits (467), Expect = 2e-46
Identities = 97/216 (44%), Positives = 132/216 (60%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EV +AGR++ R +G+ F I D IQ+ + +N +G K+ V GDIVG
Sbjct: 63 EVQVAGRIMTRRAMGKATFITIQDMSGKIQLYVARDNLPEGV--YKDDVGTWDLGDIVGI 120
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KTKTDEL++ ++ +L+ LR LP + GL D E N ESR F
Sbjct: 121 KGTLFKTKTDELTVKTTEVQLLTKALRPLPDKFHGLTDQEVRYRQRYLDLISNEESRRTF 180
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
I RSKV+ +R + I K F+EVETP+L IPGGA+A+PF+T HN L + YLR++PELY
Sbjct: 181 IIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYL 240
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
+L+VGG RVFE+ + FRNEG+ + HNPEFT E+
Sbjct: 241 KRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEY 276
>gi|135135|sp|P13030|SYK1_ECOLI LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|146341
(J03795) herC protein [Escherichia coli] >gi|887840
(U28375) lysyl tRNA synthetase (LysRS), constitutive
[Escherichia coli] >gi|1789256 (AE000372) lysine tRNA
synthetase, constitutive; suppressor of ColE1 mutation
in primer RNA [Escherichia coli]
Length = 505
Score = 183 bits (460), Expect = 1e-45
Identities = 96/215 (44%), Positives = 135/215 (62%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EV++AGR++ R +G+ +F + D G IQ+ + ++ +G N E GDI+G
Sbjct: 67 EVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYN--EQFKKWDLGDILGA 124
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KTKT ELSI ++ +L+ LR LP + GL+D E N ESRN F
Sbjct: 125 KGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTF 184
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
RS++++ +R F++ + F+EVETP++ IPGGAAA+PFIT HN L + YLR++PELY
Sbjct: 185 KVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYL 244
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 245 KRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|68526|pir||SYECKT lysine--tRNA ligase (EC 6.1.1.6) - Escherichia coli
Length = 505
Score = 183 bits (460), Expect = 1e-45
Identities = 96/215 (44%), Positives = 135/215 (62%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EV++AGR++ R +G+ +F + D G IQ+ + ++ +G N E GDI+G
Sbjct: 67 EVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYN--EQFKKWDLGDILGA 124
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KTKT ELSI ++ +L+ LR LP + GL+D E N ESRN F
Sbjct: 125 KGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTF 184
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
RS++++ +R F++ + F+EVETP++ IPGGAAA+PFIT HN L + YLR++PELY
Sbjct: 185 KVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAPELYL 244
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 245 KRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|1311301|pdb|1LYL|A Chain A, Lysyl-Trna Synthetase (Lysu) (E.C.6.1.1.6) Complexed With
Lysine >gi|1311303|pdb|1LYL|B Chain B, Lysyl-Trna
Synthetase (Lysu) (E.C.6.1.1.6) Complexed With Lysine
>gi|1311305|pdb|1LYL|C Chain C, Lysyl-Trna Synthetase
(Lysu) (E.C.6.1.1.6) Complexed With Lysine
Length = 504
Score = 180 bits (451), Expect = 1e-44
Identities = 93/215 (43%), Positives = 134/215 (62%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + GDI+G
Sbjct: 66 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDLGDIIGA 123
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KT+T ELSI ++ +L+ LR LP + GL+D E N +SR F
Sbjct: 124 RGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 183
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR++PELY
Sbjct: 184 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYL 243
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 244 KRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 278
>gi|68527|pir||SYECKU lysine--tRNA ligase (EC 6.1.1.6), thermoinducible - Escherichia
coli
Length = 505
Score = 180 bits (451), Expect = 1e-44
Identities = 93/215 (43%), Positives = 134/215 (62%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + GDI+G
Sbjct: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDLGDIIGA 124
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KT+T ELSI ++ +L+ LR LP + GL+D E N +SR F
Sbjct: 125 RGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 184
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR++PELY
Sbjct: 185 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYL 244
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 245 KRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|464826|sp|P14825|SYK2_ECOLI LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361209|pir||S56358 lysine--tRNA ligase (EC 6.1.1.6)
- Escherichia coli >gi|398703|emb|CAA34542| (X16542)
lysyl-tRNA synthetase (AA 1-505) [Escherichia coli]
>gi|536974 (U14003) lysyl-tRNA synthetase [Escherichia
coli] >gi|1790571 (AE000485) lysine tRNA synthetase,
inducible; heat shock protein [Escherichia coli]
Length = 505
Score = 180 bits (451), Expect = 1e-44
Identities = 93/215 (43%), Positives = 134/215 (62%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + GDI+G
Sbjct: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDLGDIIGA 124
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KT+T ELSI ++ +L+ LR LP + GL+D E N +SR F
Sbjct: 125 RGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 184
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + YLR++PELY
Sbjct: 185 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYL 244
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFEI + FRNEGI + HNPEFT E
Sbjct: 245 KRLVVGGFERVFEINRNFRNEGISVRHNPEFTMME 279
>gi|730872|sp|P41255|SYK_THETH LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1072959|pir||A55589 lysine--tRNA ligase (EC 6.1.1.6)
- Thermus aquaticus >gi|486665|emb|CAA50039| (X70708)
lysine--tRNA ligase [Thermus thermophilus]
Length = 492
Score = 177 bits (444), Expect = 8e-44
Identities = 99/231 (42%), Positives = 135/231 (57%)
Query: 697 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTN 518
+K+K + EEEV++AGR++A R +G+V F +LD+ IQ+ + T
Sbjct: 37 LKAKRGAPPESEWPEEEVAVAGRLVALRRMGKVTFAHLLDETGRIQLYF-----QRDLTP 91
Query: 517 LKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXX 338
E++ + GDI+G G+P TKT E+++ V D L L LP + GL+D E
Sbjct: 92 KYELLKKLDVGDILGVRGHPFTTKTGEVTVKVLDWTPLVKSLHPLPDKWHGLRDKEVRYR 151
Query: 337 XXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHN 158
+N E R F RS+++ Y+R F K F+EVETPIL GGA A+PF T+HN
Sbjct: 152 QRYLDLIVNPEVREVFRRRSEIVRYIRRFFEAKGFLEVETPILQPTTGGAEARPFKTYHN 211
Query: 157 ELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L FYLR+S ELY +L+VGG +VFEIG+ FRNEGID HNPEFT E
Sbjct: 212 ALDHEFYLRISLELYLKRLLVGGYEKVFEIGRNFRNEGIDHNHNPEFTMLE 262
>gi|730871|sp|P41258|SYK_CAMJE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|281472|pir||A42609 lysine--tRNA ligase (EC 6.1.1.6)
- Campylobacter jejuni >gi|144208 (M63448) transfer
RNA-Lys synthetase [Campylobacter jejuni]
Length = 501
Score = 172 bits (432), Expect = 2e-42
Identities = 100/236 (42%), Positives = 145/236 (61%), Gaps = 4/236 (1%)
Query: 709 TIKEIKSKYS-TCQSNSKSEEEVS--MAGRVIATRNIGRVNFYKILDDGEIIQIVIIANN 539
++K K K+S + K +E V+ +AGR+ R G+ F I D+ +QI ++
Sbjct: 34 SLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDS 93
Query: 538 A-EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGL 362
E+ T LK+ N++ GDIV G+P TKT E S+ ++ + + + LP ++ GL
Sbjct: 94 VGEELYTILKK---NLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGL 150
Query: 361 KDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
D E +N+E R F+ RSKV++ +R+F K F+EVETP+++ I GGA A
Sbjct: 151 TDIEQRYRKRYVDMIMNVEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANA 210
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
KPF+TFHN L +LR++PELY +LIVGG VFEI + FRNEG+DLTHNPEFT+ EF
Sbjct: 211 KPFVTFHNSLGVERFLRIAPELYLKRLIVGGFEAVFEINRCFRNEGMDLTHNPEFTTIEF 270
>gi|2961644 (AF052056) lysyl-tRNA synthetase [Campylobacter jejuni]
Length = 355
Score = 172 bits (432), Expect = 2e-42
Identities = 100/236 (42%), Positives = 145/236 (61%), Gaps = 4/236 (1%)
Query: 709 TIKEIKSKYS-TCQSNSKSEEEVS--MAGRVIATRNIGRVNFYKILDDGEIIQIVIIANN 539
++K K K+S + K +E V+ +AGR+ R G+ F I D+ +QI ++
Sbjct: 34 SLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIEDEDTNLQIYFSKDS 93
Query: 538 A-EDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGL 362
E+ T LK+ N++ GDIV G+P TKT E S+ ++ + + + LP ++ GL
Sbjct: 94 VGEELYTILKK---NLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGL 150
Query: 361 KDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
D E +N+E R F+ RSKV++ +R+F K F+EVETP+++ I GGA A
Sbjct: 151 TDIEQRYRKRYVDMIMNVEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANA 210
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
KPF+TFHN L +LR++PELY +LIVGG VFEI + FRNEG+DLTHNPEFT+ EF
Sbjct: 211 KPFVTFHNSLGVERFLRIAPELYLKRLIVGGFEAVFEINRCFRNEGMDLTHNPEFTTIEF 270
>gi|2983651 (AE000728) lysyl-tRNA synthetase [Aquifex aeolicus]
Length = 597
Score = 172 bits (431), Expect = 3e-42
Identities = 97/215 (45%), Positives = 130/215 (60%)
Query: 646 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGFT 467
VS+AGR+++ R++G+ F I D IQI + + G+ LK I GDIVG
Sbjct: 154 VSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVI--GEEKLKFFNDYIDVGDIVGVR 211
Query: 466 GYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFI 287
G +T T EL++ V++ +L+ L LP + GLKD E N E+R F+
Sbjct: 212 GKLFRTNTGELTVEVEEYQLLAKSLHPLPEKWHGLKDVEVRYRQRYLDLIANPEARRIFM 271
Query: 286 TRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHX 107
R+K+I +R F FIEVETPIL I GA A+PF+T+HN L++ YLR++PELY
Sbjct: 272 LRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIAPELYLK 331
Query: 106 KLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
+LIVGG RV+EIGK FRNE +D THNPEFT EF
Sbjct: 332 RLIVGGFPRVYEIGKNFRNESVDRTHNPEFTMVEF 366
>gi|2501020|sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|567884
(L36472) lysyl-tRNA synthetase [Staphylococcus aureus]
Length = 495
Score = 171 bits (429), Expect = 5e-42
Identities = 96/238 (40%), Positives = 139/238 (58%), Gaps = 1/238 (0%)
Query: 718 VKNTIKEIKSKYSTCQSNSK-SEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIAN 542
+ + +KE +YS + K ++ V++AGR++ R G+ F + D IQI + +
Sbjct: 36 LSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKD 95
Query: 541 NAEDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGL 362
D + +L + N GDIVG G KT T ELS+ +L+ LR LP + GL
Sbjct: 96 QVGDDEFDLWK---NADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGL 152
Query: 361 KDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
+D E N +S FI RSK+I +RN+L K F+EVETP+++ I GGAAA
Sbjct: 153 QDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAA 212
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+PF+T HN L + Y+R++ EL+ +LIVGGL +V+EIG+ FRNEG+ HNPEFT E
Sbjct: 213 RPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIE 271
>gi|2501017|sp|P56126|SYK_HELPY LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2313270|gb|AAD07251.1| (AE000538) lysyl-tRNA
synthetase (lysS) [Helicobacter pylori 26695]
Length = 501
Score = 169 bits (424), Expect = 2e-41
Identities = 92/214 (42%), Positives = 130/214 (59%)
Query: 643 SMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGFTG 464
S+ GRV R +G+ F K+ D+ I+Q+ + N D +LK+ +++ GDIV G
Sbjct: 59 SIVGRVKLLRLMGKACFIKVEDESTILQVYVSQNELNDEFKSLKK---HLEVGDIVLVKG 115
Query: 463 YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFIT 284
+P TKT ELSI + ILS + LP + GL D E +N ++ F
Sbjct: 116 FPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPSVKDVFKK 175
Query: 283 RSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHXK 104
RS +++ +R F + F+EVETP+++ IPGGA A+PFIT+HN L+ YLR++PELY +
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVERYLRIAPELYLKR 235
Query: 103 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
LIVGG VFEI + FRNEG+D +HNPEFT EF
Sbjct: 236 LIVGGFEAVFEINRNFRNEGMDHSHNPEFTMIEF 269
>gi|586058|sp|P37477|SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2127132|pir||S66111 lysyl-tRNA thynthetase -
Bacillus subtilis >gi|467470|dbj|BAA05316| (D26185)
lysyl-tRNA thynthetase [Bacillus subtilis]
>gi|2632349|emb|CAB11858| (Z99104) lysyl-tRNA synthetase
[Bacillus subtilis]
Length = 499
Score = 168 bits (422), Expect = 3e-41
Identities = 93/233 (39%), Positives = 138/233 (58%), Gaps = 2/233 (0%)
Query: 703 KEIKSKYSTCQSNSKSEE--EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 530
+E+ S Y E+ EV++AGR++ R G+ F + D IQI + ++ D
Sbjct: 44 QEVISAYQDLTKEELEEKAIEVTIAGRMMTKRGKGKAGFAHLQDLEGQIQIYVRKDSVGD 103
Query: 529 GKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 350
+ E+ + GD++G TG KT ELS+ +L+ LR LP ++ GLKD E
Sbjct: 104 DQY---EIFKSSDLGDLIGVTGKVFKTNVGELSVKATSFELLTKALRPLPDKYHGLKDVE 160
Query: 349 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 170
+N +S++ FITRSK+I +R +L ++EVETP +++IPGGA+A+PFI
Sbjct: 161 QRYRQRYLDLIVNPDSKHTFITRSKIIQAMRRYLDDHGYLEVETPTMHSIPGGASARPFI 220
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
T HN L Y+R++ EL+ +LIVGGL +V+EIG+ FRNEG+ HNPEFT E
Sbjct: 221 THHNALDIPLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIE 275
>gi|4154685 (AE001455) LYSYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 501
Score = 167 bits (419), Expect = 7e-41
Identities = 93/214 (43%), Positives = 129/214 (59%)
Query: 643 SMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGFTG 464
S+ GRV R +G+ F KI D+ I+Q + N D +LK+ +++ GDIV G
Sbjct: 59 SVVGRVKLLRLMGKACFIKIEDESAILQAYVSQNELNDEFKSLKK---HLEVGDIVLVKG 115
Query: 463 YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFIT 284
+P TKT ELSI + ILS + LP + GL D E +N ++ F
Sbjct: 116 FPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPGVKDVFKK 175
Query: 283 RSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHXK 104
RS +++ +R F + F+EVETP+++ IPGGA A+PFIT+HN L+ YLR++PELY +
Sbjct: 176 RSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKR 235
Query: 103 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
LIVGG VFEI + FRNEG+D +HNPEFT EF
Sbjct: 236 LIVGGFEAVFEINRNFRNEGMDHSHNPEFTMIEF 269
>gi|2127598|pir||S69892 probable lysyl-tRNA synthetase - Mycoplasma hominis (SGC3)
Length = 488
Score = 166 bits (416), Expect = 2e-40
Identities = 98/234 (41%), Positives = 135/234 (56%), Gaps = 2/234 (0%)
Query: 703 KEIKSKYSTCQSNSKSEEEVSMA--GRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 530
KE+ KY ++ + GR++ R + +L D Q+ I AN
Sbjct: 38 KELNEKYKNLSREDLDKQNLEFVFNGRIMTIRGP-----FIVLQDN-CGQMQIYANKKTL 91
Query: 529 GKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 350
+++ K + GDI+ G KT TD L I DI++L+ L+ LP + GL D E
Sbjct: 92 NESSAKTFSL-MDFGDILSVRGTLSKTNTDALVIKAQDIVLLTKSLKPLPDKFHGLVDPE 150
Query: 349 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 170
+N ++RN F+ R+++I +R + +IEV+TPILN I GGAAAKPFI
Sbjct: 151 ERRRQRYVDLIMNEKTRNTFVMRTQIIKGIREYFDSLNYIEVDTPILNPILGGAAAKPFI 210
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
TF+N L NFYLR++ EL KLIVGGL+RV+EIG+ FRNEG+D THNPEFTS EF
Sbjct: 211 TFYNALNRNFYLRIATELPLKKLIVGGLDRVYEIGRIFRNEGVDTTHNPEFTSIEF 266
>gi|3329245 (AE001350) Lysyl tRNA Synthetase [Chlamydia trachomatis]
Length = 526
Score = 164 bits (412), Expect = 4e-40
Identities = 91/219 (41%), Positives = 136/219 (61%), Gaps = 7/219 (3%)
Query: 661 KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVI------IANNAED-GKTNLKEMV 503
K +V AGR++ R++G+ +F +ILD+ IQ++ +A A D G + +K +
Sbjct: 62 KETPKVRFAGRLVLFRSMGKNSFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIE 121
Query: 502 XNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXX 323
+ GDI+G GY T + EL++ V+ + +L L +LP +H GL D E
Sbjct: 122 KKLDLGDILGLEGYLFFTHSGELTVLVETVTLLCKSLISLPDKHAGLADKEIRYRKRWAD 181
Query: 322 XXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSN 143
+ + R F+TRS+++ +R ++ Q+ F+EVETPIL I GGA A PF+T L +
Sbjct: 182 LISSEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTIYGGAEATPFVTTLQALHAE 241
Query: 142 FYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+LR+S E+ KL+VGG++RV+EIGK FRNEGID THNPEFT E
Sbjct: 242 MFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIE 287
>gi|1174528|sp|P46191|SYK_MYCHO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|581319|emb|CAA52877| (X74912) putative lysyl-tRNA
synthetase [Mycoplasma hominis]
Length = 488
Score = 162 bits (407), Expect = 2e-39
Identities = 96/234 (41%), Positives = 133/234 (56%), Gaps = 2/234 (0%)
Query: 703 KEIKSKYSTC--QSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 530
KE+ KY + K E GR++ R + +L D Q+ I AN
Sbjct: 38 KELNEKYKNLSREDTDKQNTEFVFNGRIMTIRGP-----FIVLQDN-CGQMQIYANKKTL 91
Query: 529 GKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 350
+++ K + GDI+ G KT TD L + D++ L+ L+ LP + GL D E
Sbjct: 92 NESSAKTFSL-MDFGDILSVRGTLSKTNTDALVMKAQDMVTLTKSLKPLPDKFHGLVDPE 150
Query: 349 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 170
+N ++RN F+ R+++I +R + +IEV+TPILN + GGAAAKPFI
Sbjct: 151 ERRRQRYVDLMMNEKTRNTFVMRTQIIKGIREYFDSLNYIEVDTPILNPMLGGAAAKPFI 210
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
TF+N NFYLR++ EL KLIVGGL+RV+EIG+ FRNEG+D THNPEFTS EF
Sbjct: 211 TFYNATNRNFYLRIATELPLKKLIVGGLDRVYEIGRMFRNEGVDTTHNPEFTSIEF 266
>gi|4377254|gb|AAD19069| (AE001673) Lysyl tRNA Synthetase [Chlamydia pneumoniae]
Length = 527
Score = 161 bits (403), Expect = 5e-39
Identities = 91/220 (41%), Positives = 131/220 (59%), Gaps = 7/220 (3%)
Query: 664 SKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVI------IANNAEDGK-TNLKEM 506
S+S V AGR++ R +G+ F +ILD + IQ++ + +ED + T +K +
Sbjct: 61 SRSTPRVRFAGRLVLFRAMGKNAFGQILDHNQTIQVMFNREFTSVHGLSEDAEITPIKFI 120
Query: 505 VXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXX 326
+ GDI+G GY T + EL++ V+ + +L L +LP +H GL D E
Sbjct: 121 EKKLDLGDILGIDGYLFFTHSGELTVLVETVTLLCKSLLSLPDKHAGLSDKEVRYRKRWL 180
Query: 325 XXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKS 146
+ E + F+ RS +I +RN++ F+EVETPIL NI GGA AKPF T L S
Sbjct: 181 DLISSREVSDTFVKRSYIIKLIRNYMDAHGFLEVETPILQNIYGGAEAKPFTTTMEALHS 240
Query: 145 NFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+LR+S E+ K++VGG R++E+GK FRNEGID THNPEFT E
Sbjct: 241 EMFLRISLEIALKKILVGGAPRIYELGKVFRNEGIDRTHNPEFTMIE 287
>gi|2501021|sp|P73443|SYK_SYNY3 LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1652562|dbj|BAA17483| (D90906) lysyl-tRNA synthetase
[Synechocystis sp.]
Length = 510
Score = 160 bits (401), Expect = 9e-39
Identities = 84/238 (35%), Positives = 138/238 (57%), Gaps = 4/238 (1%)
Query: 718 VKNTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANN 539
+ + ++++ Y + + + +V++AGR++A R +G++ F+ + D+ IQ+ +
Sbjct: 38 ITHQAQDLQETYRDLSNGEEVDLKVAIAGRILARRVMGKLAFFTLQDESGTIQLYLEKQR 97
Query: 538 AEDGKTNLKEMVXNIKR----GDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEH 371
+ L+ +K+ GDI+G TG +T+ ELS++V +L+ L LP +
Sbjct: 98 LTEHMPELENAFNLLKKITDVGDILGVTGTLKRTEKGELSVYVQTYAVLTKSLLPLPDKW 157
Query: 370 FGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGG 191
GL DTE +N R F R+++ +R +L ++ FIE+ETP+L GG
Sbjct: 158 HGLTDTEKRYRQRYVDLIVNPTVRQTFRRRAQITAAIRRYLDKQGFIEIETPVLQGESGG 217
Query: 190 AAAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTS 11
A A+PFIT HN L YLR++ EL+ +L+VGG +VFE+G+ FRNEG+ HNPEFTS
Sbjct: 218 AEARPFITHHNTLGMPLYLRIATELHLKRLVVGGFEKVFELGRIFRNEGVSTRHNPEFTS 277
Query: 10 CE 5
E
Sbjct: 278 IE 279
>gi|3582260 (M27221) lysyl-tRNA synthetase [Sinorhizobium meliloti]
Length = 498
Score = 160 bits (401), Expect = 9e-39
Identities = 96/235 (40%), Positives = 137/235 (57%), Gaps = 1/235 (0%)
Query: 709 TIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAED 530
T E+ KY+ + +++S E V++AGRV ++RN G F + D IQI + A +
Sbjct: 42 TNAELAEKYAGLEPDTESGETVTVAGRVFSSRNSGM--FMDLHDASGKIQIFSHKDTAPE 99
Query: 529 GKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 350
L M I GDI+G TG +TK EL++ +I +L L +P ++ GL D E
Sbjct: 100 EARALLPM---IDLGDIIGVTGEVRRTKRGELTVNAKEITMLCKSLLPMPEKYHGLADIE 156
Query: 349 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFI 170
+N ES+ RF RS++++ LR FL + F+EVETP+L I GGA A+PF
Sbjct: 157 TRYRKRYLDIMVNEESKLRFQQRSRIVSSLRRFLEDEGFMEVETPMLQPIYGGATAEPFK 216
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGL-NRVFEIGKQFRNEGIDLTHNPEFTSCE 5
T HN LK + YLR++ ELY ++V GL ++VFEI + FRNEG+ HNPEFT E
Sbjct: 217 THHNTLKLDMYLRIAAELYLNAILVSGLTDKVFEINRNFRNEGVSTRHNPEFTMME 272
>gi|1351162|sp|P47382|SYK_MYCGE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1361711|pir||A64215 lysine--tRNA ligase (EC 6.1.1.6)
- Mycoplasma genitalium (SGC3) >gi|3844726 (U39693)
lysyl-tRNA synthetase (lysS) [Mycoplasma genitalium]
Length = 490
Score = 158 bits (396), Expect = 3e-38
Identities = 93/233 (39%), Positives = 132/233 (55%), Gaps = 1/233 (0%)
Query: 703 KEIKSKYSTCQSNS-KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDG 527
K + ++ C K + VS+AGR+IA R F I D +Q+ I N +
Sbjct: 39 KSFQVEFEKCSEEELKKKATVSLAGRIIAIRQ----TFLIIQDFDGQVQLYI---NKKIH 91
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEX 347
+ GD + +G P TKT L++ V+++ I++ CL P + GL D E
Sbjct: 92 PKLFDYFNEFVDIGDQIVVSGKPMLTKTKVLTLAVEEMKIIAKCLLVPPEKWHGLTDIET 151
Query: 346 XXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFIT 167
N+ R+ F+ R+K+I +R+FL Q FIEVETP L + GGA AKPF T
Sbjct: 152 RARKRFLDLTYNLAMRDVFLKRTKIIKSIRSFLDQNGFIEVETPTLQAVLGGANAKPFKT 211
Query: 166 FHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+N LK++FYLR++ E+ KLI+GG N+V+E+GK FRNEG+D THNPEFTS E
Sbjct: 212 HYNALKADFYLRIANEIALKKLIIGGFNKVYEMGKMFRNEGVDTTHNPEFTSIE 265
>gi|1838991|emb|CAB06635| (Z85982) lysX [Mycobacterium tuberculosis]
Length = 1172
Score = 157 bits (393), Expect = 7e-38
Identities = 85/217 (39%), Positives = 124/217 (56%)
Query: 655 EEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIV 476
+ VS++GR++ RN G V F ++ D +Q+++ + + G ++ GD+V
Sbjct: 723 QASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDL--GDLV 780
Query: 475 GFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRN 296
TG+ G +KT S+ V ++ CLR LP + GL D E +N ESR
Sbjct: 781 EMTGHMGASKTGTPSLIVSGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRA 840
Query: 295 RFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPEL 116
RS V+ +R L K F+EVETPIL + GGA A+PF+T N + +LR++PEL
Sbjct: 841 LITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATARPFVTHINTYSMDLFLRIAPEL 900
Query: 115 YHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
Y +L VGG+ RVFE+G+ FRNEG+D +HNPEFT E
Sbjct: 901 YLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLE 937
>gi|146689 (M30630) lysyl-tRNA synthetase (lysU) (E.C. 6.1.1.6) [Escherichia
coli]
Length = 501
Score = 157 bits (392), Expect = 1e-37
Identities = 90/215 (41%), Positives = 129/215 (59%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EVS+AGR++ R +G+ +F + D G IQ+ + ++ +G N + GDI+G
Sbjct: 67 EVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDSLPEGVYN--DQFKKWDLGDIIG- 123
Query: 469 TGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRF 290
G KT+T ELSI ++ +L+ LR LP + GL+D E N +SR F
Sbjct: 124 AGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTF 183
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYH 110
+ RSK++ +R F++ + F+EVETP++ IPGGA+A+PFIT HN L + Y R++PELY
Sbjct: 184 VVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYARIAPELYL 243
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+L+VGG RVFE RNEGI HNPEFT E
Sbjct: 244 KRLVVGGFERVFE--HVTRNEGI-RRHNPEFTMME 275
>gi|2501016|sp|Q43990|SYK_ACICA LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1359473|emb|CAA86924| (Z46863) lysyl-tRNA-synthase
[Acinetobacter sp. ADP1]
Length = 509
Score = 157 bits (392), Expect = 1e-37
Identities = 86/224 (38%), Positives = 128/224 (56%)
Query: 673 QSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNI 494
Q + V +AGRV+ R +F I D IQ+ + + + + E + ++
Sbjct: 66 QIEGSDKTYVKVAGRVMLNRG----SFMVIQDMTGRIQLYV---DRKGLPADTLETIKSL 118
Query: 493 KRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXL 314
GDI+ GY G++ +L + ++ +L+ LR LP + GL DTE +
Sbjct: 119 DLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFHGLTDTEAKYRKRYLDLIV 178
Query: 313 NMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYL 134
N E+R F R++V+ +R FL + F+EVETP+++ IPGGA+A+PF+T HN L YL
Sbjct: 179 NEETRKTFEIRAQVVAGIRAFLTNQRFMEVETPMMHVIPGGASAQPFVTHHNALDMELYL 238
Query: 133 RVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
R++PELY +L+VGG RVFEI + FRNEG+ HNPEFT EF
Sbjct: 239 RIAPELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEF 282
>gi|2501018|sp|Q49158|SYK_MYCFE LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS) >gi|1263074
(U50826) lysyl-tRNA synthetase [Mycoplasma fermentans]
Length = 488
Score = 154 bits (386), Expect = 5e-37
Identities = 90/237 (37%), Positives = 134/237 (55%), Gaps = 2/237 (0%)
Query: 712 NTIKEIKSKYSTCQSNSKSEEEV--SMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANN 539
+T E+ KY ++V +++GR+I R F + D IQ+ N
Sbjct: 36 STSDELNKKYGQFAREELEAKKVKKNISGRLITARG----PFLVLKDRKGTIQVYF--NK 89
Query: 538 AEDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLK 359
E+ + L ++V GDI+ G KT T E+++ DI +L+ L+ LP + GL
Sbjct: 90 KENPE--LTKIVETFDLGDILWVRGLLMKTHTCEMTVRAQDIQLLTKALKPLPDKFHGLT 147
Query: 358 DTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAK 179
DTE N ESRN FI R+K++ ++R++ + +++E ETP L++ GAAAK
Sbjct: 148 DTEERYRHRYLDLITNPESRNTFIMRTKIVQWIRDYFNKLDYLEAETPFLHDYLSGAAAK 207
Query: 178 PFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
PF T HN L +F LR++ E+ KL+VGG RV+E+G+ FRNEG D THNPEFT+ EF
Sbjct: 208 PFTTHHNSLNQDFVLRIATEIPLKKLVVGGFERVYEMGRIFRNEGYDTTHNPEFTTIEF 266
>gi|2501019|sp|P75500|SYK_MYCPN LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2146330|pir||S73884 lysine--tRNA ligase (EC 6.1.1.6)
lysS - Mycoplasma pneumoniae (SGC3) (ATCC 29342)
>gi|1674257 (AE000055) Mycoplasma pneumoniae, lysyl-tRNA
synthetase; similar to Swiss-Prot Accession Number
P37477, from B. subtilis [Mycoplasma pneumoniae]
Length = 489
Score = 152 bits (380), Expect = 3e-36
Identities = 93/223 (41%), Positives = 132/223 (58%), Gaps = 2/223 (0%)
Query: 673 QSNSKSEE-EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXN 497
QS+++ ++ +V + GR+IA R F I D +Q+ I A + L E N
Sbjct: 48 QSDAELKQYQVILTGRIIALRQ----TFIIIQDFSGKMQLYINKKTAPE----LFEYFNN 99
Query: 496 -IKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXX 320
I GD + TG+P TKT L++ V+ + I++ CL+T P + GL D E
Sbjct: 100 YIDLGDQIVATGHPMMTKTGVLTLNVERLQIVAKCLQTPPEKWHGLTDPEARARKRYLDL 159
Query: 319 XLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF 140
N F+ R+++I +R FL + F+EVETPIL + GGA AKPF T +N LK +F
Sbjct: 160 TYNRAQVEVFLKRTQIITAIRTFLNEAGFLEVETPILQAVLGGANAKPFKTHYNALKGDF 219
Query: 139 YLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
YLR++ E+ KLIVGGL +V+E+G+ FRNEG+D THNPEFTS E
Sbjct: 220 YLRIANEIALKKLIVGGLPKVYEMGRMFRNEGVDTTHNPEFTSIE 264
>gi|2501022|sp|P95970|SYK_SULSO LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|1707804|emb|CAA69561| (Y08257) lysyl tRNA synthetase
[Sulfolobus solfataricus]
Length = 494
Score = 147 bits (367), Expect = 8e-35
Identities = 95/238 (39%), Positives = 126/238 (52%), Gaps = 3/238 (1%)
Query: 718 VKNTIKEIKSKYSTCQSNSKSEE---EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII 548
V + IK+IK + Q N E +S AGRV R G+ +F I D+GE +Q+ +
Sbjct: 30 VTHLIKDIKL-IAKSQGNKSHEPFMFNISTAGRVANIRRHGKASFVDIFDEGEKLQLYM- 87
Query: 547 ANNAEDGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHF 368
++ K + + RGDI+G G T ELS+ V D +LS L P +
Sbjct: 88 --RVDELKEKYDKFFIYVGRGDIIGVKGDLFYTMKGELSLLVKDYQLLSKALIEPP--DW 143
Query: 367 GLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGA 188
E N +R R +I +R FL K FIEVETPI+ + GGA
Sbjct: 144 SKLSPEFRYAHRYVDFLYNDNARKAMEIRYTIIREIREFLYSKGFIEVETPIVQPVYGGA 203
Query: 187 AAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSC 8
AKPF T N L ++YLR++ ELY + I+GG N+VFEIGK FRNE ID+THNPEFT
Sbjct: 204 LAKPFKTHVNYLNEDWYLRIALELYLKRYIIGGFNKVFEIGKVFRNEDIDVTHNPEFTLL 263
Query: 7 E 5
E
Sbjct: 264 E 264
>gi|3122897|sp|O06284|SYK_MYCTU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA LIGASE) (LYSRS)
>gi|2113978|emb|CAB08946| (Z95557) lysS [Mycobacterium
tuberculosis]
Length = 505
Score = 143 bits (356), Expect = 2e-33
Identities = 84/236 (35%), Positives = 133/236 (55%)
Query: 712 NTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAE 533
+T+ E+++ + ++ +E+ V +AGRVI RN G++ F L DG+ Q+ ++ + +
Sbjct: 40 HTLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCF-ATLQDGDGTQLQVMISLDK 98
Query: 532 DGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT 353
G+ L ++ GDIV G ++ ELS+ D I + LR LPV H + +
Sbjct: 99 VGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSE- 157
Query: 352 EXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPF 173
E + E+R R V+ +R L ++ F+EVETP+L + GGAAA+PF
Sbjct: 158 ESRVRQRYVDLIVRPEARAVARLRIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPF 217
Query: 172 ITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
T N L + YLR++PEL+ + IVGG ++VFE+ + FRNEG D TH+PEF+ E
Sbjct: 218 ATHSNALDIDLYLRIAPELFLKRCIVGGFDKVFELNRVFRNEGADSTHSPEFSMLE 273
>gi|3766370|emb|CAA21422| (AL031907) lysyl-trna synthetase [Schizosaccharomyces pombe]
Length = 531
Score = 140 bits (350), Expect = 8e-33
Identities = 86/221 (38%), Positives = 133/221 (59%), Gaps = 10/221 (4%)
Query: 667 NSKSEEEVSMA-----GRVIATRNIG-RVNFYKILDDGEIIQIVIIANNA---EDGKTNL 515
N ++ E++M GR+ + R G ++ F+ +L + +Q+V N E+ K
Sbjct: 72 NKITKSEIAMVRYTVCGRISSIRYSGSKLAFFDVLYGNKKLQVVFNKKNIGTEEEMKGKF 131
Query: 514 KEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDII-ILSPCLRTLPVEHFGLKDTEXXXX 338
+ +++GD + +G G++ + ELSI+ ++ +LSPCL +PV+ L + E
Sbjct: 132 IPRLKALQKGDCIQCSGNVGRSGSGELSIYATELPKLLSPCLHPIPVK---LTNYEKRFE 188
Query: 337 XXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHN 158
N +S R ++I +R F ++ F+EVETPIL++ GGA A+PFIT
Sbjct: 189 KRFVDMMSNTKSLELLEKRYRIIESIRKFFSERGFLEVETPILSHHFGGATARPFITSDI 248
Query: 157 ELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
K LR +PEL+ +L++GG+NRVFE+GK FRNEGID THNPEFTSCE
Sbjct: 249 H-KLPLTLRCAPELWLKQLVIGGMNRVFELGKNFRNEGIDATHNPEFTSCE 298
>gi|1351160|sp|P32048|SYKM_YEAST LYSYL-TRNA SYNTHETASE, MITOCHONDRIAL PRECURSOR (LYSINE--TRNA
LIGASE) (LYSRS) >gi|418811|pir||S14834 lysine--tRNA
ligase (EC 6.1.1.6) precursor, mitochondrial - yeast
(Saccharomyces cerevisiae) >gi|791113|emb|CAA60187|
(X86470) lysine--tRNA ligase [Saccharomyces cerevisiae]
>gi|1301959|emb|CAA95947| (Z71349) ORF YNL073w
[Saccharomyces cerevisiae]
Length = 576
Score = 118 bits (294), Expect = 3e-26
Identities = 82/215 (38%), Positives = 125/215 (58%), Gaps = 14/215 (6%)
Query: 646 VSMAGRVIATRNIGRVNFYKILDDGEI-------IQIVI----IANNAEDGKTNLKEMVX 500
+S+ GR+ + R G+ + L +G +Q+++ I ++ED K N E +
Sbjct: 101 LSINGRIKSIRFSGQKIVFIDLYNGSSGLKNDTQLQLIVNYNKIGGSSED-KANFSEYMN 159
Query: 499 NIKRGDIVGFTGYPG--KTKTDELSIFVDDI-IILSPCLRTLPVEHFGLKDTEXXXXXXX 329
+K+GD + GYPG +++ LS+ + + I+LS LP L D
Sbjct: 160 FLKKGDYIKALGYPGFSQSRVKMLSLICNKLPIVLSVSQLPLPSR---LNDETKIKSNRV 216
Query: 328 XXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELK 149
LN + R+++I LR FL + F+EVETPIL++ GA AKPFIT +
Sbjct: 217 VDYQLN--GTQTLLVRARIIKLLRKFLDDRNFVEVETPILSSKSNGAMAKPFITSSKDF- 273
Query: 148 SNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
+ LR++PEL+ +LI+ GL +V+EIGK FRNEGID THN EF++ EF
Sbjct: 274 DHLELRIAPELWLKRLIISGLQKVYEIGKVFRNEGIDSTHNAEFSTLEF 322
>gi|450763|emb|CAA40634| (X57360) lysine--tRNA ligase [Saccharomyces cerevisiae]
Length = 576
Score = 105 bits (260), Expect = 3e-22
Identities = 62/183 (33%), Positives = 100/183 (53%), Gaps = 3/183 (1%)
Query: 550 IANNAEDGKTNLKEMVXNIKRGDIVGFTGYPG--KTKTDELSIFVDDI-IILSPCLRTLP 380
I ++ED K N E + +K+GD + TGYPG +++ S+ + ++LS LP
Sbjct: 144 IGGSSED-KANFSEYMNFLKKGDYIKATGYPGFSQSRVKMTSLMCNKTPMVLSVSQTPLP 202
Query: 379 VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI 200
+ + + R+++I LR F + F+EVETP+ ++
Sbjct: 203 S-----RTNDETKIKSNRVVDYQLNGTQTTTVRARIIKTLRKFTDDRNFVEVETPMTSSK 257
Query: 199 PGGAAAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPE 20
GA AKPF+T + + LR++PEL+ + ++ GL +V+E+GK FRNEGID THN E
Sbjct: 258 SNGAMAKPFMTSSKDF-DHLELRIAPELWTKRTMISGLQKVYEMGKVFRNEGIDSTHNAE 316
Query: 19 FTSCEF 2
F++ EF
Sbjct: 317 FSTLEF 322
>gi|3915067|sp|O67589|SYD_AQUAE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2984003 (AE000750) aspartyl-tRNA synthetase [Aquifex
aeolicus]
Length = 603
Score = 75.7 bits (183), Expect = 3e-13
Identities = 69/231 (29%), Positives = 108/231 (45%), Gaps = 14/231 (6%)
Query: 694 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 515
++KY S +EV +AG V R+ G V F + D I+Q+V+ + KTN
Sbjct: 10 RTKYCGEVSEEDIGKEVKLAGWVHRKRHHGGVIFIDLRDREGIVQVVV------EEKTNP 63
Query: 514 K--EMVXNIKRGDIVGFTGYPGKT---------KTDELSIFVDDIIILSPC-LRTLPVEH 371
+ E+ +K ++G G K KT + + D I++ + PVE
Sbjct: 64 EAYEVADKLKSEYVIGVVGKVRKRPEGTENPKLKTGYVEVVADRILVFNTSEALPFPVEE 123
Query: 370 FGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILN-NIPG 194
+E +N I R +V RNF ++ FIE+ETP L + P
Sbjct: 124 -ETHVSEETKLKYRYIDLRRESMKNNLIFRHRVYQITRNFFTKEGFIEIETPFLTKSTPE 182
Query: 193 GAAAKPFITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEF 17
GA + F+ FY L SP+L+ L++ G +R F+I K FR+E + PEF
Sbjct: 183 GA--RDFLVPSRLHPGKFYALPQSPQLFKQILMIAGFDRYFQIVKCFRDEDLRADRQPEF 240
Query: 16 TSCEF 2
T ++
Sbjct: 241 TQIDY 245
>gi|4155111 (AE001489) ASPARTYL-TRNA SYNTHETASE [Helicobacter pylori J99]
Length = 579
Score = 72.6 bits (175), Expect = 3e-12
Identities = 60/231 (25%), Positives = 106/231 (44%), Gaps = 3/231 (1%)
Query: 697 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-ANNAEDGKT 521
++S + T S + + +AG R+ G V F + D ++Q+V ++ A +
Sbjct: 1 MRSHFCTEISEKDVGKTIKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 520 NLKEMVXNIKRGD--IVGFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEX 347
++ + +G + G K KT ++ I +++++I + T P+E E
Sbjct: 61 EVRSEFVLVAKGKARLRGAGLENPKLKTGKIEIVLEELVIENKSA-TPPIEIGNKSVNED 119
Query: 346 XXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFIT 167
++ + F RS+V RN L QK F+E+ETPIL+ A +
Sbjct: 120 LRLKYRYLDLRSLNAYEIFKLRSEVALITRNALAQKGFLEIETPILSKTTPEGARDYLVP 179
Query: 166 FHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
F L SP+L+ L+VGG++R F+I + FR+E + PEFT +
Sbjct: 180 SRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQID 233
>gi|3024680|sp|P56459|SYD_HELPY ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2313739|gb|AAD07682.1| (AE000576) aspartyl-tRNA
synthetase (aspS) [Helicobacter pylori 26695]
Length = 577
Score = 72.2 bits (174), Expect = 4e-12
Identities = 63/231 (27%), Positives = 105/231 (45%), Gaps = 3/231 (1%)
Query: 697 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-ANNAEDGKT 521
++S + T S + V +AG R+ G V F + D ++Q+V ++ A +
Sbjct: 1 MRSHFCTEISEKDVGKIVKVAGWCNTYRDHGGVVFIDLRDKSGLVQLVCDPSSKAYEKAL 60
Query: 520 NLKEMVXNIKRGDIV--GFTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEX 347
++ + +G + G K KT ++ I ++++II + T P+E E
Sbjct: 61 EVRSEFVLVAKGKVRLRGAGLENPKLKTGKIEIVLEELIIENKSA-TPPIEIGNKHVNED 119
Query: 346 XXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFIT 167
+ S F RS+V RN L QK F+E+ETPIL+ A +
Sbjct: 120 LRLKYRYLDLRSPNSYEIFKLRSEVALITRNTLAQKGFLEIETPILSKTTPEGARDYLVP 179
Query: 166 FHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
F L SP+L+ L+VGG++R F+I + FR+E + PEFT +
Sbjct: 180 SRVHEGEFFALPQSPQLFKQLLMVGGMDRYFQIARCFRDEDLRADRQPEFTQID 233
>gi|2500967|sp|Q48979|SYD_MYCCA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|530412|emb|CAA83720| (Z33048) Asp-tRNA synthetase
[Mycoplasma capricolum]
Length = 483
Score = 69.5 bits (167), Expect = 2e-11
Identities = 47/168 (27%), Positives = 85/168 (49%), Gaps = 9/168 (5%)
Query: 508 MVXNIKRGDIVGFTGYPGKTK-------TDELSIFVDDIIILSPCLRTLPVEHFGLKDTE 350
++ N+K ++ +G K K T E+ + V D+++++ T V + E
Sbjct: 16 LINNLKNEYVIEISGIVVKRKSVNKELITGEIEVIVKDLLVINKSELTPFVLENDVNVNE 75
Query: 349 XXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPF 173
+N I R+K+ + +RN+L F+EVETP + P GA + F
Sbjct: 76 DTRLTYRYLDLRRQVMQNNLIIRAKINHIIRNYLTDLNFLEVETPYFAKSTPEGA--RHF 133
Query: 172 ITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+ K+ FY L SP+L+ L++ G++R ++I + FR+E + + PEFT +
Sbjct: 134 LVPSRLNKNKFYALPQSPQLFKQLLMISGIDRYYQIVRCFRDEDLRIDRQPEFTQLD 190
>gi|1174503|sp|P43817|SYD_HAEIN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1073870|pir||E64061 aspartate--tRNA ligase (EC
6.1.1.12) - Haemophilus influenzae (strain Rd KW20)
>gi|1573287 (U32717) aspartyl-tRNA synthetase (aspS)
[Haemophilus influenzae Rd]
Length = 588
Score = 66.3 bits (159), Expect = 2e-10
Identities = 61/231 (26%), Positives = 108/231 (46%), Gaps = 8/231 (3%)
Query: 697 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVII-----ANNAE 533
+++ Y + + ++V+++G V R++G + F + D I+Q+ A A
Sbjct: 2 MRTHYCGALNRNNIGQDVTLSGWVHRRRDLGGLIFIDMRDRDGIVQVCFDPKYQDALTAA 61
Query: 532 DGKTNLKEMVXNIKRGDIVGFTGYPGKTK-TDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
G N E IK I K T E+ + ++ I + LP++ F +
Sbjct: 62 AGLRN--EFCIQIKGEVIARPDNQINKNMATGEVEVLAKELRIYNAS-DVLPLD-FNQNN 117
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI-PGGAAAK 179
TE E R TR+K+ +++R F+ F+++ETP+L P GA +
Sbjct: 118 TEEQRLKYRYLDLRRPEMAQRLKTRAKITSFVRRFMDDNGFLDIETPMLTKATPEGA--R 175
Query: 178 PFITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
++ K FY L SP+L+ L++ G +R ++I K FR+E + PEFT +
Sbjct: 176 DYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQID 234
>gi|4378708|gb|AAD19636| (AF108665) lysyl-tRNA synthetase homolog [Buchnera aphidicola]
Length = 324
Score = 66.0 bits (158), Expect = 3e-10
Identities = 38/94 (40%), Positives = 56/94 (59%), Gaps = 6/94 (6%)
Query: 283 RSKVINYLRNFLIQKEFIEVETPILNNIP-GGAAAKPFITFH-----NELKSNFYLRVSP 122
RSK+I +R+F ++K +EVETPIL+ PFIT + N K N +L SP
Sbjct: 17 RSKIIADIRSFFLKKNIMEVETPILSQSGVTDVNLMPFITNYFSFNDNIKKKNLWLITSP 76
Query: 121 ELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
E + +L+ G +++I + FRN+ HNPEFT E+
Sbjct: 77 EYHMKRLLSAGSGSIYQICRSFRNQEFGQYHNPEFTMLEW 116
>gi|2500973|sp|Q52428|SYD_PYRKO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2129413|pir||JC4352 aspartate--tRNA ligase (EC
6.1.1.12) - Pyrococcus sp >gi|1136773|dbj|BAA08115|
(D45167) aspartyl-tRNA synthetase [Pyrococcus sp.]
Length = 438
Score = 64.4 bits (154), Expect = 8e-10
Identities = 59/223 (26%), Positives = 99/223 (43%), Gaps = 5/223 (2%)
Query: 694 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 515
++ YS+ + + ++V +AG V +++G + F I D I+QI + L
Sbjct: 3 RTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDP---EL 59
Query: 514 KEMVXNIKRGDIVGFTGYPGKTKTDELS--IFVDDIIILSPCLRTLPVEHFGLKDTEXXX 341
+++ ++ D+V G T +L I + I++L+ LP++ G E
Sbjct: 60 FKLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDT 119
Query: 340 XXXXXXXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 170
L E F RS V +R+F + FIE+ TP I GG P
Sbjct: 120 RLDNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHN 26
F + +L SP+LY ++ GL+RV+EI FR E + T +
Sbjct: 180 YFEEDA----FLAQSPQLYKQIMMASGLDRVYEIAPIFRAEEHNTTRH 223
>gi|4388836|pdb|1B8A|A Chain A, Aspartyl Trna Synthetase From Pyrococcus Kodakaraensis
>gi|4388837|pdb|1B8A|B Chain B, Aspartyl Trna Synthetase
From Pyrococcus Kodakaraensis
Length = 438
Score = 64.4 bits (154), Expect = 8e-10
Identities = 59/223 (26%), Positives = 99/223 (43%), Gaps = 5/223 (2%)
Query: 694 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 515
++ YS+ + + ++V +AG V +++G + F I D I+QI + L
Sbjct: 3 RTHYSSEITEELNGQKVKVAGWVWEVKDLGGIKFLWIRDRDGIVQITAPKKKVDP---EL 59
Query: 514 KEMVXNIKRGDIVGFTGYPGKTKTDELS--IFVDDIIILSPCLRTLPVEHFGLKDTEXXX 341
+++ ++ D+V G T +L I + I++L+ LP++ G E
Sbjct: 60 FKLIPKLRSEDVVAVEGVVNFTPKAKLGFEILPEKIVVLNRAETPLPLDPTGKVKAELDT 119
Query: 340 XXXXXXXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 170
L E F RS V +R+F + FIE+ TP I GG P
Sbjct: 120 RLNNRFMDLRRPEVMAIFKIRSSVFKAVRDFFHENGFIEIHTPKIIATATEGGTELFPMK 179
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHN 26
F + +L SP+LY ++ GL+RV+EI FR E + T +
Sbjct: 180 YFEEDA----FLAESPQLYKEIMMASGLDRVYEIAPIFRAEEHNTTRH 223
>gi|1174524|sp|P43826|SYK3_HAEIN HYPOTHETICAL LYSYL-TRNA SYNTHETASE HOMOLOG (GX)
Length = 323
Score = 63.6 bits (152), Expect = 1e-09
Identities = 36/96 (37%), Positives = 53/96 (54%), Gaps = 7/96 (7%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 131
+ R+K+I +R F ++ +EVETP+L+ G TF E + F +L
Sbjct: 17 LKRAKIIAKIRQFFTERGLLEVETPVLSEF--GVTDLHLSTFSTEFLAPFGEQSKTLWLS 74
Query: 130 VSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
SPE + +L+ G +F+I K FRNE HNPEFT E+
Sbjct: 75 TSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEW 117
>gi|1074996|pir||I64097 lysyl-tRNA synthetase analog (genX) homolog - Haemophilus
influenzae (strain Rd KW20) >gi|1573850 (U32765)
lysyl-tRNA synthetase analog (genX) [Haemophilus
influenzae Rd]
Length = 333
Score = 63.6 bits (152), Expect = 1e-09
Identities = 36/96 (37%), Positives = 53/96 (54%), Gaps = 7/96 (7%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 131
+ R+K+I +R F ++ +EVETP+L+ G TF E + F +L
Sbjct: 27 LKRAKIIAKIRQFFTERGLLEVETPVLSEF--GVTDLHLSTFSTEFLAPFGEQSKTLWLS 84
Query: 130 VSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
SPE + +L+ G +F+I K FRNE HNPEFT E+
Sbjct: 85 TSPEYHMKRLLAAGSGPIFQISKVFRNEEAGNRHNPEFTMLEW 127
>gi|2500971|sp|P73851|SYD_SYNY3 ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1652993|dbj|BAA17910| (D90910) aspartyl-tRNA
synthetase [Synechocystis sp.]
Length = 599
Score = 63.2 bits (151), Expect = 2e-09
Identities = 58/216 (26%), Positives = 94/216 (42%), Gaps = 13/216 (6%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVG 473
E V++ G V R+ G V F + D I+QI ++ D + ++ +V
Sbjct: 16 ETVTLYGWVDRRRDHGGVIFLDLRDRQGIVQIA----SSPDQTPASYPVAEGLRNEYVVQ 71
Query: 472 FTGYPGKTK---------TDELSIFVDDIIILSPCLRTLPV---EHFGLKDTEXXXXXXX 329
TG K T E+ I+ D II+L+ + LP H + E
Sbjct: 72 VTGVVSKRPPESLNEKIPTGEIEIYADSIILLNGVNQQLPFVVSSHEAEQVREDVRLKYR 131
Query: 328 XXXXLNMESRNRFITRSKVINYLRNFLIQKE-FIEVETPILNNIPGGAAAKPFITFHNEL 152
R +V+ +R FL +E F+E+ETPIL A +
Sbjct: 132 YLDLRRARLSQNLQLRHQVVKAMRRFLEDQENFLEIETPILTRSTPEGARDYLVPSRVNP 191
Query: 151 KSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+ L SP+L+ L+V G++R ++I + FR+E + PEFT +
Sbjct: 192 GEWYALPQSPQLFKQLLMVAGMDRYYQIARCFRDEDLRADRQPEFTQLD 240
>gi|3915063|sp|O51402|SYD_BORBU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2688349 (AE001149) aspartyl-tRNA synthetase (aspS)
[Borrelia burgdorferi]
Length = 506
Score = 63.2 bits (151), Expect = 2e-09
Identities = 46/148 (31%), Positives = 77/148 (51%), Gaps = 6/148 (4%)
Query: 448 KTDELSIFVDDIIILSPCLRTLPVEHFGLKD----TEXXXXXXXXXXXLNMESRNRFITR 281
KT I +I I+S C LP F ++D +E +N+ I R
Sbjct: 7 KTGHFEILAKNIEIISKC-NELP---FMIEDDNNASENSKLEYRYLDLRRDSLKNKIILR 62
Query: 280 SKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYHX 107
+ + +RNFLI+++F+E+ETP + + P G A+ F+ K +FY L SP+LY
Sbjct: 63 CQATHLIRNFLIKRKFLELETPTFVKSTPEG--ARDFVIPSRIHKGSFYALPQSPQLYKQ 120
Query: 106 KLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+++ G ++ F+I + +R+E PEFT +
Sbjct: 121 LIMIAGFDKYFQIARCYRDEDSRGDRQPEFTQLD 154
>gi|3328981 (AE001325) Aspartyl tRNA Synthetase [Chlamydia trachomatis]
Length = 582
Score = 62.5 bits (149), Expect = 3e-09
Identities = 68/228 (29%), Positives = 107/228 (46%), Gaps = 20/228 (8%)
Query: 688 KYSTCQSNSKS----EEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKT 521
KY T + N S E V ++G V RN G V F + D I QIV ++
Sbjct: 2 KYRTHKCNELSLDHVGEHVRLSGWVHRYRNHGGVVFIDLRDCFGITQIVC----RQEENP 57
Query: 520 NLKEMVXNIKRGDIVGFTGYP---------GKTKTDELSIFVDDIIILSPCLRTLPVEHF 368
L +++ ++ ++ G T + + V + +LS + LP F
Sbjct: 58 ELHQLMDQVRSEWVLCVEGLVCARLEGMENPNLVTGSIEVEVSSLEVLSRA-QNLP---F 113
Query: 367 GLKDTEXXXXXXXXXXXLNMESR-----NRFITRSKVINYLRNFLIQKEFIEVETPILN- 206
+ D ++ R +R + R KV+ R +L ++ F EV TPIL
Sbjct: 114 SISDEHINVNEELRLTYRYLDMRRGDILDRLMCRHKVMLACRQYLDEQGFTEVVTPILGK 173
Query: 205 NIPGGAAAKPFITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTH 29
+ P GA + ++ NFY L SP+L+ L+VGGL+R F+I FR+E +
Sbjct: 174 STPEGA--RDYLVPSRIYPGNFYALPQSPQLFKQILMVGGLDRYFQIATCFRDEDLRADR 231
Query: 28 NPEFTSCE 5
PEFT +
Sbjct: 232 QPEFTQID 239
>gi|135102|sp|P21889|SYD_ECOLI ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68534|pir||SYECD aspartate--tRNA ligase (EC
6.1.1.12) - Escherichia coli >gi|41015|emb|CAA37856|
(X53863) aspartate-tRNA ligase [Escherichia coli]
>gi|1736513|dbj|BAA15677| (D90829) Aspartate--tRNA
ligase (EC 6.1.1.12) [Escherichia coli] >gi|1788173
(AE000280) aspartate tRNA synthetase [Escherichia coli]
Length = 590
Score = 61.7 bits (147), Expect = 5e-09
Identities = 54/216 (25%), Positives = 101/216 (46%), Gaps = 11/216 (5%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVG 473
++V++ G V R++G + F + D I+Q+ + A+ K + ++ +
Sbjct: 16 QQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALK-----LASELRNEFCIQ 70
Query: 472 FTG---------YPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXX 320
TG T E+ + + I++ LP++ + +TE
Sbjct: 71 VTGTVRARDEKNINRDMATGEIEVLASSLTIINRA-DVLPLDSNHV-NTEEARLKYRYLD 128
Query: 319 XLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPILNNI-PGGAAAKPFITFHNELKSN 143
E R TR+K+ + +R F+ F+++ETP+L P GA + ++ K
Sbjct: 129 LRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGA--RDYLVPSRVHKGK 186
Query: 142 FY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
FY L SP+L+ L++ G +R ++I K FR+E + PEFT +
Sbjct: 187 FYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQID 233
>gi|3915068|sp|P81432|SYD_BUCAP ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2947034 (L43549) aspartyl-tRNA synthetase [Buchnera
aphidicola]
Length = 584
Score = 60.9 bits (145), Expect = 9e-09
Identities = 55/216 (25%), Positives = 99/216 (45%), Gaps = 9/216 (4%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVG 473
+ V + G V RN + F + D I+Q+V N + N+K +
Sbjct: 16 KSVILCGWVHKIRNFSQFIFIDMRDWTGIVQLVFEKKN-----NKVFTKAVNLKNESCIQ 70
Query: 472 FTGYPGKTK-------TDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXL 314
G K T E+ I V+ I + + + LP+++ + +
Sbjct: 71 VIGIVKKRNANNNNLDTGEIEILVNKIKVFN-ISKNLPLDYSNNSNDDIRLKYRYLDLRR 129
Query: 313 NMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPFITFHNELKSNFY 137
+ N I R+K+ + +R F+ K F+++ETP L + P G A+ ++ NFY
Sbjct: 130 SELLENLKI-RNKITHLIRIFMENKNFLDIETPFLTKSTPEG--ARDYLVPSRNYPGNFY 186
Query: 136 -LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L SP+L+ L++ G+++ ++I K FR+E + PEFT +
Sbjct: 187 ALPQSPQLFKQILMISGIDKYYQIVKCFRDEDLRSDRQPEFTQID 231
>gi|3122880|sp|O07683|SYD_HALSA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2209068|dbj|BAA20527| (D82887) aspartyl-tRNA
synthetase [Halobacterium salinarum]
Length = 436
Score = 59.3 bits (141), Expect = 3e-08
Identities = 58/202 (28%), Positives = 92/202 (44%), Gaps = 11/202 (5%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVG 473
E+ ++AG V R++G + F + D +Q+V ED +L E + D+V
Sbjct: 17 EDTTIAGHVHELRDLGGILFVIVRDATGRLQVVA----KEDDTPDLFETAEGLSSEDVVQ 72
Query: 472 FTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGL------KDTEXXXXXXXXXXXLN 311
TG T E S + L+P T+ E + KD + L+
Sbjct: 73 VTG------TLEASDQAPGGVELAPTELTVVSEATDVPSIEISKDVDADLSTRLDERHLD 126
Query: 310 MESRNR---FITRSKVINYLRNFLIQKEFIEVETPILNNI--PGGAAAKPFITFHNELKS 146
+ + F RSK + + ++ F EV+TP L+ GGA P + + E
Sbjct: 127 VRKPSTKAVFSLRSKAMGAMTDWFYDNRFEEVDTPELSTAGAEGGADLFPVVYYDKEA-- 184
Query: 145 NFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNE 47
YL SP+LY L+ G++R+FE+G FR E
Sbjct: 185 --YLSQSPQLYKQILVASGVDRLFEVGHAFRAE 215
>gi|4101633 (AF005272) lysyl-tRNA synthetase homolog [Haemophilus
paragallinarum]
Length = 322
Score = 59.3 bits (141), Expect = 3e-08
Identities = 36/96 (37%), Positives = 54/96 (55%), Gaps = 7/96 (7%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNF-------YLR 131
++R+K+I +R F ++ +EVETPIL+ G TF +L S F +L
Sbjct: 16 LSRAKIIAEIRQFFSERGLLEVETPILSEF--GVTDVHLSTFSTKLISPFQKKEKTLWLS 73
Query: 130 VSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
SPE +L+ G +F++ K FRNE H+PEFT E+
Sbjct: 74 TSPEYPMKRLLSAGSGAIFQLCKVFRNEEAGKKHSPEFTMLEW 116
>gi|3323310 (AE001266) aspartyl-tRNA synthetase (aspS) [Treponema pallidum]
Length = 602
Score = 59.3 bits (141), Expect = 3e-08
Identities = 59/214 (27%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Query: 646 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGFT 467
V + G V R+ G V+F+ + D I+Q+++ +++ +L V I+ +
Sbjct: 35 VVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIV----SQEENASLWSTVNRIRLECCLAVE 90
Query: 466 GYPGKTK---------TDELSIFVDDIIILSPCLRTLPVEHFGLKDT----EXXXXXXXX 326
G + T E+ + + +LS LP F + D E
Sbjct: 91 GVVRERPPSMINRALHTGEVEVHARTLYVLSENA-VLP---FRVDDVVHAHEDIRLKYRY 146
Query: 325 XXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELK 149
+ + R RS+V +R FL K FIE+ETP + + P GA + F+
Sbjct: 147 LDLRSQRMQERIALRSRVALAIRQFLSMKGFIEIETPTFICSTPEGA--RDFVVPSRVCP 204
Query: 148 SNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
FY L SP+LY L+V G +R F++ + +R+E PEFT +
Sbjct: 205 GRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQPEFTQID 253
>gi|3122885|sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2635219|emb|CAB14714| (Z99118) aspartyl-tRNA
synthetase [Bacillus subtilis]
Length = 592
Score = 58.9 bits (140), Expect = 3e-08
Identities = 57/216 (26%), Positives = 103/216 (47%), Gaps = 12/216 (5%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLK----EMVXNIKRG 485
E V++ G V R++G + F + D I+Q+V + +++ + E V +I+
Sbjct: 18 ESVTLKGWVQKRRDLGGLIFIDLRDRTGIVQVVFNPDVSKEALAIAEGIRNEYVLDIQGK 77
Query: 484 DIVGFTGYPGKT-KTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNM 308
+ G KT + I D + +L+ +T P F + D +
Sbjct: 78 VVAREEGTVNPNLKTGAIEIHADGVNVLNAA-KTPP---FAISDQAEEVSEDVRLKHRYL 133
Query: 307 ESRNRFI-----TRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNELKS 146
+ R + R V +R+FL + F+++ETPIL + P GA + ++ +
Sbjct: 134 DLRRPAMFQTMQLRHNVTKAVRSFLDENGFLDIETPILTGSTPEGA--RDYLVPSRVHEG 191
Query: 145 NFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
FY L SP+L+ L+V G+ R ++I + FR+E + PEFT +
Sbjct: 192 EFYALPQSPQLFKQLLMVSGIERYYQIARCFRDEDLRADRQPEFTQID 239
>gi|4376961|gb|AAD18801| (AE001648) Aspartyl tRNA Synthetase [Chlamydia pneumoniae]
Length = 584
Score = 58.2 bits (138), Expect = 6e-08
Identities = 65/228 (28%), Positives = 103/228 (44%), Gaps = 20/228 (8%)
Query: 688 KYSTCQSNSKSE----EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKT 521
KY T + N + E V +AG V RN G V F + D I QIV ED +
Sbjct: 2 KYRTHRCNELTSNHIGENVQLAGWVHRYRNHGGVVFIDLRDRFGITQIVC----REDEQP 57
Query: 520 NLKEMVXNIKRGDIVGFTGYP---------GKTKTDELSIFVDDIIILSPCLRTLPVEHF 368
L + + ++ ++ G T + + V +LS + LP F
Sbjct: 58 ELHQRLDAVRSEWVLSVRGKVCPRLAGMENPNLATGHIEVEVASFEVLSKS-QNLP---F 113
Query: 367 GLKDTEXXXXXXXXXXXLNMESRN-----RFITRSKVINYLRNFLIQKEFIEVETPILN- 206
+ D ++ R + + R +V+ RNF+ + F E+ TP+L
Sbjct: 114 SIADDHINVNEELRLEYRYLDMRRGDIIEKLLCRHQVMLACRNFMDAQGFTEIVTPVLGK 173
Query: 205 NIPGGAAAKPFITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTH 29
+ P GA + ++ FY L SP+L+ L+VGGL+R F+I FR+E +
Sbjct: 174 STPEGA--RDYLVPSRIYPGKFYALPQSPQLFKQLLMVGGLDRYFQIATCFRDEDLRADR 231
Query: 28 NPEFTSCE 5
PEF +
Sbjct: 232 QPEFAQID 239
>gi|2500972|sp|Q58950|SYD_METJA ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2127776|pir||B64494 aspartate--tRNA ligase (EC
6.1.1.12) - Methanococcus jannaschii >gi|1592183
(U67596) aspartyl-tRNA synthetase (aspS) [Methanococcus
jannaschii]
Length = 438
Score = 57.8 bits (137), Expect = 8e-08
Identities = 61/222 (27%), Positives = 93/222 (41%), Gaps = 8/222 (3%)
Query: 712 NTIKEIKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAE 533
N +K ++ YS +EV + G V + R +G++ F + D +QIV
Sbjct: 3 NKMKWRRTHYSADIKPEMDGQEVIIMGWVHSIRALGKIIFVILRDREGTVQIVAPKQKVG 62
Query: 532 DGKTNLKEMVXNIKRGDIVGFTGYPGKTKTDE-----LSIFVDDIIILSPCLRTLPVEHF 368
D E+ IK+ GK +E I ++ +++ R LP++
Sbjct: 63 D------ELFSQIKKLGAEDVIAVKGKVIANEKAPNGFEILPLELEVINTAKRPLPLDPA 116
Query: 367 GLKDTEXXXXXXXXXXXLNMESRNR-FITRSKVINYLRNFLIQKEFIEVETP--ILNNIP 197
E L F RS+++ +RN L + FIEV TP + +
Sbjct: 117 EKVPAELDTRLENRFLDLRRPKVQAIFKIRSEMLKSVRNTLYNEGFIEVNTPKLVASCTE 176
Query: 196 GGAAAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNE 47
GG P F E +L SP+LY L+ GL+RVFEI FR E
Sbjct: 177 GGTELFPISYFEREA----FLGQSPQLYKQMLMATGLDRVFEIAPIFRAE 222
>gi|3257434|dbj|BAA30117| (AP000004) 438aa long hypothetical aspartyl-tRNA synthetase
[Pyrococcus horikoshii]
Length = 438
Score = 57.8 bits (137), Expect = 8e-08
Identities = 56/224 (25%), Positives = 96/224 (42%), Gaps = 9/224 (4%)
Query: 697 IKSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTN 518
+++ YS + + + V +AG V +++G + F I D I+Q+
Sbjct: 2 LRTHYSNEITEELNGKRVKVAGWVQEVKDLGGIKFIWIRDREGIVQVTAPKKKVSQ---E 58
Query: 517 LKEMVXNIKRGDIVGFTGYPGKTKTDELSIFV--DDIIILSPCLRTLPVEHFGLKDTEXX 344
+ +++ + D++ G T +L V + + ++S LP++ G E
Sbjct: 59 IFKLIPKLNSEDVIVVEGIVNFTPKAKLGFEVIPEKLEVISRAKTPLPLDPTGKVKAELD 118
Query: 343 XXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAA 185
M+ RN F RS V +R F + FIE+ TP I GG
Sbjct: 119 TRLDNRF----MDLRNPKVMAIFKIRSSVFRAVREFFYSEGFIEIHTPKIIATATEGGTE 174
Query: 184 AKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHN 26
P F + +L SP+LY ++ GL++VFEI FR E + T +
Sbjct: 175 LFPLKYFERDA----FLAQSPQLYKQMMMATGLDKVFEIAPIFRAEEHNTTRH 223
>gi|2500968|sp|P75068|SYD_MYCPN ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2146065|pir||S73434 aspartate--tRNA ligase (EC
6.1.1.12) aspS - Mycoplasma pneumoniae (SGC3) (ATCC
29342) >gi|1673765 (AE000013) Mycoplasma pneumoniae,
aspartyl-tRNA synthetase; similar to Swiss-Prot
Accession Number P36419, from T. aquaticus [Mycoplasma
pneumoniae]
Length = 557
Score = 57.0 bits (135), Expect = 1e-07
Identities = 61/214 (28%), Positives = 91/214 (42%), Gaps = 3/214 (1%)
Query: 646 VSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGFT 467
V++AG V + +G +NF + D IQ+ KE V + R D+V
Sbjct: 27 VTIAGWVKRIKKLGELNFVIVGDKTNTIQVTC----------KNKEQVKYLTREDLVIVK 76
Query: 466 GYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT-EXXXXXXXXXXXLNMESRNRF 290
G + + I + I L +T P+ D E + R
Sbjct: 77 GKLKRLDSVRFEI-TNPTITLFAKSKTPPLIIEDKTDALEEVRLRYRYLDLRRPVMQKRL 135
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNELKSNFY-LRVSPEL 116
R KV +RN+L Q FIEVETP L + P GA + F+ + +FY L SP++
Sbjct: 136 ALRHKVTLAVRNWLDQMGFIEVETPTLTKSTPEGA--RDFLVPARIREHSFYALPQSPQI 193
Query: 115 YHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
Y L+VGG + F+I +R+E PE T +
Sbjct: 194 YKQLLMVGGTEKYFQIAHVYRDEDSRKDRQPEHTQID 230
>gi|549026|sp|P36419|SYD_THETH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|420805|pir||S33743 aspartate--tRNA ligase (EC
6.1.1.12) - Thermus aquaticus >gi|396501|emb|CAA50282|
(X70943) aspartyl-tRNA synthetase [Thermus thermophilus]
Length = 580
Score = 57.0 bits (135), Expect = 1e-07
Identities = 30/93 (32%), Positives = 51/93 (54%)
Query: 283 RSKVINYLRNFLIQKEFIEVETPILNNIPGGAAAKPFITFHNELKSNFYLRVSPELYHXK 104
R +VI + +FL ++ F++VETP L A + + +E + L SP+L+
Sbjct: 147 RHRVIKAIWDFLDREGFVQVETPFLTKSTPEGARDFLVPYRHEPGLFYALPQSPQLFKQM 206
Query: 103 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L+V GL+R F+I + FR+E + P+FT +
Sbjct: 207 LMVAGLDRYFQIARCFRDEDLRADRQPDFTQLD 239
>gi|3875743|emb|CAB04081| (Z81497) similar to aspartyl-tRNA synthetase; cDNA EST yk250e3.3
comes from this gene [Caenorhabditis elegans]
Length = 569
Score = 56.6 bits (134), Expect = 2e-07
Identities = 50/164 (30%), Positives = 83/164 (50%), Gaps = 16/164 (9%)
Query: 496 IKRGDI-VGFTGYPGKTKTDELS----------IFVDDIIILSPCLRTLPVEHFGLKDTE 350
+K GDI V F Y K+ +E S I V+++ +L+ +P+ L D
Sbjct: 54 MKTGDIEVNFQKYYFKSGNNENSNREVFDFLILIDVEELTVLNKATSNIPM----LPDAN 109
Query: 349 XXXXXXXXXXXLNMES---RNRFITRSKVINYLRNFLIQKE-FIEVETPIL-NNIPGGAA 185
+++ S + RS+ ++ +R FL++K F++VETP L PGGAA
Sbjct: 110 ANERTRLKYRYIDLRSDKLQKSLRLRSEFVHNVRRFLVEKSGFVDVETPTLFRRTPGGAA 169
Query: 184 AKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+ L SP+ + L+VG ++R F+I + +R+EG PEFT +
Sbjct: 170 EFVVPAPSPNQGLAYSLPQSPQQFKQLLMVGAIDRYFQIARCYRDEGSKGDRQPEFTQVD 229
>gi|3122882|sp|O26328|SYD_METTH ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2621273 (AE000809) aspartyl-tRNA synthetase
[Methanobacterium thermoautotrophicum]
Length = 437
Score = 55.8 bits (132), Expect = 3e-07
Identities = 59/230 (25%), Positives = 104/230 (44%), Gaps = 6/230 (2%)
Query: 694 KSKYSTCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNL 515
++ YS +EV++ G V R++G + F + D +IQI + E +L
Sbjct: 8 RTHYSKDIEPEMDGDEVTVMGWVHEIRDLGGIIFVLLRDRDGLIQITAPSKKIEK---DL 64
Query: 514 KEMVXNIKRGDIVGFTGYPGKT--KTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXX 341
+ + +K+ +V F G ++ I + +L+ + LP++ E
Sbjct: 65 FKSIRKLKKESVVAFGGTVQESGKAPGGFEIIPSFLKVLNISKQPLPLDPTEKVKAEIDT 124
Query: 340 XXXXXXXXLNMESRNR-FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFI 170
L S + F +S++++ +R FL ++ F+E+ TP + + GG P
Sbjct: 125 RLDARFLDLRKPSVSAIFKIKSRMLHSVRVFLEEQGFLEINTPKLVASATEGGTELFPIT 184
Query: 169 TFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGID-LTHNPEFTSCE 5
F E +L SP+LY ++ GL+RV+EI FR E D L H E S +
Sbjct: 185 YFEREA----FLGQSPQLYKQIMMSTGLDRVYEIAPIFRAEEHDTLRHLNEVISID 236
>gi|135101|sp|P15179|SYDM_YEAST ASPARTYL-TRNA SYNTHETASE, MITOCHONDRIAL (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|2144551|pir||SYBYDM aspartate--tRNA ligase
(EC 6.1.1.12), mitochondrial - yeast (Saccharomyces
cerevisiae) >gi|172872 (M26020) aspartyl-tRNA synthetase
[Saccharomyces cerevisiae] >gi|173036 (M24418)
mitochondrial aspartyl-tRNA synthetase [Saccharomyces
cerevisiae] >gi|1151223 (U43281) Msd1p [Saccharomyces
cerevisiae]
Length = 658
Score = 55.4 bits (131), Expect = 4e-07
Identities = 54/204 (26%), Positives = 94/204 (45%), Gaps = 8/204 (3%)
Query: 616 RNIGRVNFYKILDD--GEIIQIVIIANNAEDGKTNLKEMVXN--IKRGDIVGFTGYPGKT 449
+ +G+ + +L D G+IIQ+V D K+ LK ++ I+
Sbjct: 61 KRVGKNLIFGLLRDSNGDIIQLV-------DNKSLLKGFTLEDVVQAVGILSLKRKLSNE 113
Query: 448 KTDELSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVI 269
DE + ++DI +L+ + P + K + N + ++ RS +
Sbjct: 114 DADEYEVQLEDITVLNASNKK-PAQMQDFKLSAIYPPEFRYLQLRNPKYQDFLKKRSSIS 172
Query: 268 NYLRNFLIQKEFIEVETPIL-NNIPGGAAA--KPFITFHNELKSNFY-LRVSPELYHXKL 101
+RN +F EVETP+L P GA P T ++ K +FY L SP+ Y L
Sbjct: 173 KEIRNSFNNFDFTEVETPMLFKATPEGAREFLVPTRTKRSDGKPSFYALDQSPQQYKQLL 232
Query: 100 IVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+ G+N+ +++ + FR+E + PEFT +
Sbjct: 233 MASGVNKYYQMARCFRDEDLRADRQPEFTQVD 264
>gi|3122883|sp|O29342|SYD_ARCFU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|2649677 (AE001040) aspartyl-tRNA synthetase (aspS)
[Archaeoglobus fulgidus]
Length = 430
Score = 55.4 bits (131), Expect = 4e-07
Identities = 56/209 (26%), Positives = 91/209 (42%), Gaps = 10/209 (4%)
Query: 652 EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVG 473
++V++ G V R++G + F + D I+QI + + ++ I+R ++
Sbjct: 15 QKVTLYGWVHEVRDLGGLVFILLRDREGIVQITLPRKFVSK---QVFKLAKKIRRESVIA 71
Query: 472 FTGYPGKTKTDE--LSIFVDDIIILSPCLRTLPVEHFGLKDTEXXXXXXXXXXXLNMESR 299
TG + + + I + I +L+ LP+E TE
Sbjct: 72 VTGEVRREEKAPGGVEIIPESIEVLNEADAPLPLEV-----TEKVPAELDTRLDHRFMDL 126
Query: 298 NR------FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNELKSN 143
R F R +V+ +R FL ++ FIEV TP + GG P F E
Sbjct: 127 RRPRVQAIFRIRHQVMQSVREFLSEEGFIEVHTPKIVSTATEGGTELFPISYFEKEA--- 183
Query: 142 FYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHN 26
+L SP+LY L+ G +VFEIG FR E + T +
Sbjct: 184 -FLNQSPQLYKQVLMAAGFEKVFEIGPIFRAEEHNTTRH 221
>gi|1351148|sp|P47282|SYD_MYCGE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1361448|pir||I64203 aspartate--tRNA ligase (EC
6.1.1.12) - Mycoplasma genitalium (SGC3) >gi|3844646
(U39683) aspartyl-tRNA synthetase (aspS) [Mycoplasma
genitalium]
Length = 550
Score = 55.0 bits (130), Expect = 5e-07
Identities = 34/100 (34%), Positives = 56/100 (56%), Gaps = 2/100 (2%)
Query: 301 RNRFITRSKVINYLRNFLIQKEFIEVETPILN-NIPGGAAAKPFITFHNELKSNFYLRV- 128
+ R + R + I +RN+ Q+ FIE+ETP L+ + P GA + F+ K FY V
Sbjct: 126 QKRLLLRHQFILAIRNWFNQQGFIEIETPTLSKSTPEGA--QDFLVPARIRKDCFYALVQ 183
Query: 127 SPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
SP++Y L++ G+ + F+I + +R+E PE T +F
Sbjct: 184 SPQIYKQLLMIAGVEKYFQIARVYRDEDSRKDRQPEHTQIDF 225
>gi|135100|sp|P04802|SYDC_YEAST ASPARTYL-TRNA SYNTHETASE, CYTOPLASMIC (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|68532|pir||SYBYDC aspartate--tRNA ligase (EC
6.1.1.12), cytosolic - yeast (Saccharomyces cerevisiae)
>gi|3370|emb|CAA27269| (X03606) AspRS (aa 1-557)
[Saccharomyces cerevisiae] >gi|3411|emb|CAA29865|
(X06665) aspartyl tRNA synthase [Saccharomyces
cerevisiae] >gi|1297012|emb|CAA66172| (X97560)
aspartyl-tRNA synthetase [Saccharomyces cerevisiae]
>gi|1360191|emb|CAA97464| (Z73123) ORF YLL018c
[Saccharomyces cerevisiae]
Length = 557
Score = 54.3 bits (128), Expect = 9e-07
Identities = 67/228 (29%), Positives = 100/228 (43%), Gaps = 26/228 (11%)
Query: 688 KYSTCQSNSKSEEEVSMAGRVIATRNIGR-VNFYKILDDGEIIQIVIIANNAEDGKTNLK 512
K+ S++EV RV TR G + F + +IQ ++ AN N+
Sbjct: 95 KFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMV 154
Query: 511 EMVXNIKRGDIVGFTGY------PGKTKT-DELSIFVDDIIILSPCLRTLPVEHFGLKDT 353
+ ++ IV G P K+ T L I + I +S LP+ L+D
Sbjct: 155 KWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPIL---LEDA 211
Query: 352 EXXXXXXXXXXX--LNMESR------------NRFITRSK--VINYLRNFLIQKEFIEVE 221
+N+++R N+ I R + V R +L K+F EV
Sbjct: 212 SRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVH 271
Query: 220 TPILNNIPGGAAAKPF-ITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEG 44
TP L P + F +T+ K YL SP+ +LIV RV+EIG FR E
Sbjct: 272 TPKLLGAPSEGGSSVFEVTY---FKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAEN 328
Query: 43 IDL-THNPEFTSCE 5
+ H EFT +
Sbjct: 329 SNTHRHMTEFTGLD 342
>gi|1064982|pdb|1ASY|A Saccharomyces cerevisiae >gi|1064984|pdb|1ASY|B Saccharomyces
cerevisiae >gi|1064986|pdb|1ASZ|A Saccharomyces
cerevisiae >gi|1064988|pdb|1ASZ|B Saccharomyces
cerevisiae
Length = 490
Score = 54.3 bits (128), Expect = 9e-07
Identities = 67/228 (29%), Positives = 100/228 (43%), Gaps = 26/228 (11%)
Query: 688 KYSTCQSNSKSEEEVSMAGRVIATRNIGR-VNFYKILDDGEIIQIVIIANNAEDGKTNLK 512
K+ S++EV RV TR G + F + +IQ ++ AN N+
Sbjct: 28 KFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMV 87
Query: 511 EMVXNIKRGDIVGFTGY------PGKTKT-DELSIFVDDIIILSPCLRTLPVEHFGLKDT 353
+ ++ IV G P K+ T L I + I +S LP+ L+D
Sbjct: 88 KWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPIL---LEDA 144
Query: 352 EXXXXXXXXXXX--LNMESR------------NRFITRSK--VINYLRNFLIQKEFIEVE 221
+N+++R N+ I R + V R +L K+F EV
Sbjct: 145 SRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVH 204
Query: 220 TPILNNIPGGAAAKPF-ITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEG 44
TP L P + F +T+ K YL SP+ +LIV RV+EIG FR E
Sbjct: 205 TPKLLGAPSEGGSSVFEVTY---FKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAEN 261
Query: 43 IDL-THNPEFTSCE 5
+ H EFT +
Sbjct: 262 SNTHRHMTEFTGLD 275
>gi|135138|sp|P03812|SYK3_ECOLI HYPOTHETICAL LYSYL-TRNA SYNTHETASE HOMOLOG (GX)
>gi|41552|emb|CAA42604| (X59988) genX [Escherichia coli]
Length = 325
Score = 53.9 bits (127), Expect = 1e-06
Identities = 31/96 (32%), Positives = 52/96 (53%), Gaps = 5/96 (5%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 125
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 17 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 76
Query: 124 PELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
PE + +L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 77 PEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 117
>gi|1361210|pir||S56383 lysyl-tRNA synthetase homolog protein genX - Escherichia coli
>gi|536999 (U14003) lysyl-tRNA synthetase analog
[Escherichia coli] >gi|1790599 (AE000488) putative
lysyl-tRNA synthetase [Escherichia coli]
Length = 335
Score = 53.9 bits (127), Expect = 1e-06
Identities = 31/96 (32%), Positives = 52/96 (53%), Gaps = 5/96 (5%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 125
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 27 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 86
Query: 124 PELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
PE + +L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 87 PEYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 127
>gi|3298338|dbj|BAA31457| (AB010464) aspartyl tRNA synthetase [Haloferax volcanii]
Length = 433
Score = 53.9 bits (127), Expect = 1e-06
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 6/226 (2%)
Query: 679 TCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVX 500
T ++++ + V++AG V R++G + F + D IQ+ + +D +L E
Sbjct: 5 TYTADAEPGDTVTVAGWVHEVRDLGGIAFLILRDTSGKIQVKFEKDEMDD---DLVETGL 61
Query: 499 NIKRGDIVGFTGYPGKTKTDELSIFV--DDIIILSPCLRTLPVEHFGLKDTEXXXXXXXX 326
+ R ++ TG + + V + + +++ LP++ G D E
Sbjct: 62 GVHRESVISVTGEVDEEPRAPTGVEVTPESLDVIAEAEAQLPLDPSGKVDAELSTRLDNR 121
Query: 325 XXXLNM-ESRNRFITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNE 155
L E + F R++V +R+ E+ TP + GG P F E
Sbjct: 122 TLDLRKDEVKAIFEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQE 181
Query: 154 LKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDL-THNPEFTSCEF 2
++ SP+L+ ++ GL RVFE+G FR E + H E TS +F
Sbjct: 182 A----FMNQSPQLFKQLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDF 229
>gi|3860712|emb|CAA14613| (AJ235270) ASPARAGINYL-TRNA SYNTHETASE (aspS) [Rickettsia
prowazekii]
Length = 605
Score = 53.5 bits (126), Expect = 2e-06
Identities = 61/222 (27%), Positives = 97/222 (43%), Gaps = 11/222 (4%)
Query: 688 KYSTCQSN----SKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAE---D 530
KY T N S +EV ++G V R+ G + F + D I QIV N + D
Sbjct: 3 KYRTHNCNELQLSNVGQEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQNQQLMYD 62
Query: 529 GKTNLKEMVXNIKRGDIVG--FTGYPGKTKTDELSIFVDDIIILSPCLRTLPVEHFGLKD 356
E V + G +V K T + + + I+ S V + +
Sbjct: 63 ASRLCYESVITVS-GTVVARSLDTINNKLPTGYVEVLAMECIVESASSPLPFVINNEKEA 121
Query: 355 TEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAK 179
E + N I RS+VI ++R+ +I + F E++TPIL ++ P GA +
Sbjct: 122 PEESRLKHRFLDLRREKLHNNIILRSQVIAHIRHLMIARGFTELQTPILTSSSPEGA--R 179
Query: 178 PFITFHNELKSNFY-LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNP 23
F+ FY L +P+ + L+V G +R F+I FR+E +P
Sbjct: 180 DFLVPSRIHPGKFYALPQAPQQFKQLLMVAGFDRYFQIAPCFRDEDARADRSP 232
>gi|4455210|emb|CAB36533| (AL035440) putative aspartate-tRNA ligase [Arabidopsis thaliana]
Length = 504
Score = 53.1 bits (125), Expect = 2e-06
Identities = 67/232 (28%), Positives = 98/232 (41%), Gaps = 21/232 (9%)
Query: 697 IKSKYSTCQSNSKSE---EEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDG 527
++ K T SN E EVS+ GR+ R +G F + + G +Q V+
Sbjct: 68 VEGKELTDVSNLVEEIVGSEVSIRGRLHKNRLVGTKLFVILRESGFTVQCVVEETRVGAN 127
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKT---KTDELSIFVDDIIILSPCLRTLP-------- 380
+ + +++G +P K T ++ I V + LS L LP
Sbjct: 128 MIKFVKQLSRESVVELIGVVSHPKKPLTGTTQQVEIHVRKMYCLSRSLPNLPLVVEDAAR 187
Query: 379 ----VEHFGLKDTEXXXXXXXXXXXLNMESRNRFITRSKVINYLRNFLIQKEFIEVETP- 215
+E G KDT N F + +V R +L K F+E+ TP
Sbjct: 188 SESDIEKSG-KDTRLNNRVLDIRTPANQAI---FRIQCQVQIAFREYLQSKGFLEIHTPK 243
Query: 214 -ILNNIPGGAAAKPFITFHNELKSN-FYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGI 41
I + GG+A F + K L SP+L+ I G + RVFE+G FR E
Sbjct: 244 LIAGSSEGGSAV-----FRLDYKGQPACLAQSPQLHKQMAICGDMRRVFEVGPVFRAED- 297
Query: 40 DLTHNPEFTSCEF 2
TH CEF
Sbjct: 298 SFTHR---HLCEF 307
>gi|78609|pir||A04437 hypothetical protein F-162 - Escherichia coli (fragment)
Length = 162
Score = 52.7 bits (124), Expect = 3e-06
Identities = 30/96 (31%), Positives = 52/96 (53%), Gaps = 5/96 (5%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 125
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 27 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 86
Query: 124 PELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
P+ + +L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 87 PQYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 127
>gi|551785 (J01611) gene x protein (putative); putative [Escherichia coli]
Length = 151
Score = 52.7 bits (124), Expect = 3e-06
Identities = 30/96 (31%), Positives = 52/96 (53%), Gaps = 5/96 (5%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 125
+ R+ ++ +R F + +EVETP ++ +I F+ + N +L S
Sbjct: 16 LKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTS 75
Query: 124 PELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
P+ + +L+V G VF++ + FRNE + HNPEFT E+
Sbjct: 76 PQYHMKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEW 116
>gi|3947886 (AF001831) pyruvate oxidase [Salmonella typhimurium]
Length = 325
Score = 51.9 bits (122), Expect = 4e-06
Identities = 31/96 (32%), Positives = 51/96 (52%), Gaps = 5/96 (5%)
Query: 289 ITRSKVINYLRNFLIQKEFIEVETPILN-----NIPGGAAAKPFITFHNELKSNFYLRVS 125
+ R+ ++ +R F + +EVETP ++ +I F+ + N YL S
Sbjct: 17 LKRAAIMAEIRRFFGDRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINLYLMTS 76
Query: 124 PELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
PE + +L+ G VF++ + FRNE + HNPEFT E+
Sbjct: 77 PEYHMKRLLEAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEW 117
>gi|3845470|emb|CAA19270| (AL023705) hypothetical protein [Schizosaccharomyces pombe]
Length = 611
Score = 50.4 bits (118), Expect = 1e-05
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 283 RSKVINYLRNFLIQKEFIEVETPIL-NNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 110
RS++ + +F +EF EVETP+L + P GA + F+ FY L SP+ Y
Sbjct: 162 RSRLAYQVHSFFNDREFCEVETPLLFKSTPEGA--REFVVPSRLNPGKFYALPQSPQQYK 219
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L+ G+ ++I + FR+E + PEFT +
Sbjct: 220 QILMASGIGNYYQIARCFRDEDLRFDRQPEFTQID 254
>gi|2500969|sp|Q50649|SYD_MYCTU ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|1478240|emb|CAB01271| (Z77724) aspS [Mycobacterium
tuberculosis]
Length = 596
Score = 50.0 bits (117), Expect = 2e-05
Identities = 32/93 (34%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 283 RSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 110
RS+V R L + +F+E+ETP I + P GA + F+ +FY L SP+L+
Sbjct: 145 RSRVNAAARAVLARHDFVEIETPTITRSTPEGA--RDFLVPARLHPGSFYALPQSPQLFK 202
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L+V G+ R ++I + +R+E PEFT +
Sbjct: 203 QLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLD 237
>gi|549025|sp|P36429|SYD_MYCLE ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS) (ANTIGEN
T5) >gi|541455|pir||S42047 aspartate--tRNA ligase (EC
6.1.1.12) - Mycobacterium leprae
>gi|581332|emb|CAA54735| (X77655) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3136016|emb|CAA19094| (AL023591) aspartyl-tRNA
synthetase [Mycobacterium leprae]
>gi|3335328|gb||S82268_1 (S82268) aspartyl-tRNA
synthetase [Mycobacterium leprae]
Length = 589
Score = 50.0 bits (117), Expect = 2e-05
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 2/93 (2%)
Query: 283 RSKVINYLRNFLIQKEFIEVETP-ILNNIPGGAAAKPFITFHNELKSNFY-LRVSPELYH 110
RSKV R L + +F+E+ETP I + P GA + F+ FY L SP+L+
Sbjct: 140 RSKVNATARAVLARHDFVEIETPTITRSTPEGA--RDFLVPARLRPGTFYALPQSPQLFK 197
Query: 109 XKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
L+V G+ R ++I +R+E PEFT +
Sbjct: 198 QLLMVAGMERYYQIAHCYRDEDFRADRQPEFTQLD 232
>gi|3618213|emb|CAA20876| (AL031579) ASPARTYL-TRNA SYNTHETASE [Schizosaccharomyces pombe]
Length = 580
Score = 50.0 bits (117), Expect = 2e-05
Identities = 60/216 (27%), Positives = 98/216 (44%), Gaps = 31/216 (14%)
Query: 652 EEVSMAGRVIATRNIG-RVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIV 476
+ V + RV +R G ++ F+ + + IQ + + N K +K +I IV
Sbjct: 105 QTVLLRARVYTSRLQGNKMCFFSLRQKYDTIQALAVVNKDTISKQMVK-WCGSISLESIV 163
Query: 475 GFTGYPGKTK-------TDELSIFVDDIIILSPCLRTLP--VEHFGLKDT------EXXX 341
G K+ + I + I ++SP + LP VE G + E
Sbjct: 164 LVEGIVKKSPEIIKSATVQDAEIHISSIYVISPIKKNLPFLVEDAGRSEEQIRESEENAA 223
Query: 340 XXXXXXXXLNMESR--NR------------FITRSKVINYLRNFLIQKEFIEVETPILNN 203
+N+++R NR F ++ + R FL+ F E+ TP ++
Sbjct: 224 EGDSKFVRVNLDTRLDNRVLDLRTPTNQAIFDIQAGICQAFREFLLSNSFNEIHTPKMSG 283
Query: 202 IPGGAAAKPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNEGID-LTHN 26
+ F + K++ +L SP+LY LI RVFEIG FR E + H
Sbjct: 284 ASSEGGSNVFKIQY--FKTDGFLSQSPQLYKQMLIAADRERVFEIGPVFRAEDSNTYRHM 341
Query: 25 PEFTSCE 5
EFT +
Sbjct: 342 TEFTGLD 348
>gi|4557513|oth|NP_001340|PDARS aspartyl-tRNA synthetase >gi|135098|sp|P14868|SYD_HUMAN
ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE)
(ASPRS) >gi|68530|pir||SYHUDT aspartate--tRNA ligase (EC
6.1.1.12) - human >gi|179102 (J05032) aspartyl-tRNA
synthetase [Homo sapiens]
Length = 500
Score = 49.6 bits (116), Expect = 2e-05
Identities = 51/205 (24%), Positives = 86/205 (41%), Gaps = 20/205 (9%)
Query: 661 KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGD 482
K++E V + RV +R G+ F + +Q ++ + + + NI +
Sbjct: 54 KADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVG--DHASKQMVKFAANINKES 111
Query: 481 IVGFTGYP-------GKTKTDELSIFVDDIIILSPCLRTLPV--------EHFGLKDTEX 347
IV G G ++ + V I ++S LP+ E G ++
Sbjct: 112 IVDVEGVVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAVRPEQEGEEEGRA 171
Query: 346 XXXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
++ R F +S + + R LI K F+E++TP + + A
Sbjct: 172 TVNQDTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGA 231
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNE 47
F + K+N YL SP+LY I +VF IG FR E
Sbjct: 232 NVFTVSY--FKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAE 274
>gi|135099|sp|P15178|SYD_RAT ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
>gi|68531|pir||SYRTDT aspartate--tRNA ligase (EC
6.1.1.12) - rat >gi|203066 (J04487) aspartyl-tRNA
synthetase [Rattus norvegicus] >gi|1773257 (U30812)
aspartyl-tRNA synthetase [Rattus norvegicus]
Length = 501
Score = 49.2 bits (115), Expect = 3e-05
Identities = 52/205 (25%), Positives = 86/205 (41%), Gaps = 20/205 (9%)
Query: 661 KSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGD 482
K++E V + RV +R G+ F + +Q ++ + + + NI +
Sbjct: 55 KADEVVWVRARVHTSRAKGKQCFLVLRQQQFNVQALVAVG--DHASKQMVKFAANINKES 112
Query: 481 IVGFTGYP-------GKTKTDELSIFVDDIIILSPCLRTLPV--------EHFGLKDTEX 347
I+ G G ++ + V I ++S LP+ E G +D
Sbjct: 113 IIDVEGIVRKVNQKIGSCTQQDVELHVQKIYVISLAEPRLPLQLDDAIRPEVEGEEDGRA 172
Query: 346 XXXXXXXXXXLNMESRNR-----FITRSKVINYLRNFLIQKEFIEVETPILNNIPGGAAA 182
++ R F +S + + R LI K F+E++TP + + A
Sbjct: 173 TVNQDTRLDNRIIDLRTSTSQAIFHLQSGICHLFRETLINKGFVEIQTPKIISAASEGGA 232
Query: 181 KPFITFHNELKSNFYLRVSPELYHXKLIVGGLNRVFEIGKQFRNE 47
F + KSN YL SP+LY I +VF IG FR E
Sbjct: 233 NVFTVSY--FKSNAYLAQSPQLYKQMCICADFEKVFCIGPVFRAE 275
>gi|1127124|pdb|1KRT| Mol_id: 1; Molecule: Lysyl-Trna Synthetase (Product Of Lyss Gene);
Chain: Null; Domain: Anticodon-Binding Domain (Residues
40 - 149); Ec: 6.1.1.6; Engineered: Yes
>gi|1127125|pdb|1KRS| Mol_id: 1; Molecule: Lysyl-Trna
Synthetase (Product Of Lyss Gene); Chain: Null; Domain:
Anticodon-Binding Domain (Residues 40 - 149); Ec:
6.1.1.6; Engineered: Yes
Length = 120
Score = 47.6 bits (111), Expect = 9e-05
Identities = 29/83 (34%), Positives = 47/83 (55%)
Query: 649 EVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLKEMVXNIKRGDIVGF 470
EV++AGR++ R +G+ +F + D G IQ+ + ++ +G N E GDI+G
Sbjct: 38 EVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYN--EQFKKWDLGDILGA 95
Query: 469 TGYPGKTKTDELSIFVDDIIILS 401
G KTKT ELSI ++ +L+
Sbjct: 96 KGKLFKTKTGELSIHCTELRLLT 118
>gi|3323370 (AE001271) lysyl-tRNA synthetase (lysS-2) [Treponema pallidum]
Length = 351
Score = 46.5 bits (108), Expect = 2e-04
Identities = 30/94 (31%), Positives = 50/94 (52%), Gaps = 7/94 (7%)
Query: 283 RSKVINYLRNFLIQKEFIEVETPILNN--IPGGAA----AKPFITFHNELKSNFYLRVSP 122
R++ + +R+F ++ +IE++TP L +P + F + H + YL SP
Sbjct: 9 RAQCLRAVRDFFLEHHYIELDTPALARALVPERCLEVFQTEYFTSVHAKDTQKLYLVPSP 68
Query: 121 ELYHXKLIVGGLNRVFEIGKQFRN-EGIDLTHNPEFTSCEF 2
E++ LI F+I K +RN E + H PEFT E+
Sbjct: 69 EVFLKPLIAQLQRSAFQISKCYRNGESMGALHRPEFTMVEY 109
>gi|1169858|sp|P43151|GBA_LEIDO GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA SUBUNIT >gi|556256
(L36832) G protein alpha subunit [Leishmania donovani]
Length = 464
Score = 41.0 bits (94), Expect = 0.009
Identities = 24/70 (34%), Positives = 40/70 (56%), Gaps = 12/70 (17%)
Query: 571 EIIQIVIIANNAEDGKTNLKEMVXNIKRGD------------IVGFTGYPGKTKTDELSI 428
E +Q++ + D ++ E+ +KRGD I+G G P +K+ E S+
Sbjct: 12 ETVQVISALTDYID-QSKFAEIHSKLKRGDGPGESGKSTIFQIIGIAGRPSLSKSSEFSL 70
Query: 427 FVDDIIILSPCLRTLPVEHFGL 362
+I +LS C LP ++FGL
Sbjct: 71 KATEITLLSTCYHMLPDDYFGL 92
>gi|3122881|sp|O24822|SYD_HALVO ASPARTYL-TRNA SYNTHETASE (ASPARTATE--TRNA LIGASE) (ASPRS)
Length = 324
Score = 39.1 bits (89), Expect = 0.033
Identities = 30/97 (30%), Positives = 45/97 (45%), Gaps = 3/97 (3%)
Query: 292 FITRSKVINYLRNFLIQKEFIEVETP--ILNNIPGGAAAKPFITFHNELKSNFYLRVSPE 119
F R++V +R+ E+ TP + GG P F E ++ SP+
Sbjct: 25 FEIRAEVQRAVRDKFRDLRATEINTPKIVATGTEGGTELFPITYFGQEA----FMNQSPQ 80
Query: 118 LYHXKLIVGGLNRVFEIGKQFRNEGIDL-THNPEFTSCEF 2
L+ ++ GL RVFE+G FR E + H E TS +F
Sbjct: 81 LFKQLMVGSGLERVFEVGPIFRAEEHNTPRHLNEATSIDF 120
>gi|2983331 (AE000706) lysyl-tRNA synthetase (genX) homolog [Aquifex aeolicus]
Length = 293
Score = 37.9 bits (86), Expect = 0.075
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 4/90 (4%)
Query: 271 INYLRNFLIQKEFIEVETPILNNIPGGAA----AKPFITFHNELKSNFYLRVSPELYHXK 104
IN +R F +K + EV TP+L + P + K + E K +L SPE K
Sbjct: 11 INEVRKFFKEKGYTEVSTPLLLDFPNLDSNVEPVKVEVLERGENKVK-WLHTSPEYSMKK 69
Query: 103 LIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCEF 2
L+ +F+I K FRN H EF E+
Sbjct: 70 LLSRYKRDIFQITKVFRNNEWGRLHRIEFHMLEW 103
>gi|3549678|emb|CAA20589| (AL031394) putative aspartate--tRNA ligase [Arabidopsis thaliana]
Length = 636
Score = 37.1 bits (84), Expect = 0.13
Identities = 35/150 (23%), Positives = 59/150 (39%), Gaps = 7/150 (4%)
Query: 454 KTKTDELSIFVDDIIILSPCLRTLPVEHFGLKDT-----EXXXXXXXXXXXLNMESRNRF 290
K KT + + + + IL+P LP + E + +N
Sbjct: 160 KMKTGFVEVVAEHVEILNPVRTKLPFLVTTADENKDLIKEEIRLRFRCLDLRRQQMKNNI 219
Query: 289 ITRSKVINYLRNFLIQKE-FIEVETPILNNIPGGAAAKPFITFHNELKSNFY-LRVSPEL 116
+ R V+ +R +L + FIE T FY L SP+L
Sbjct: 220 VLRHNVVKLIRRYLEDRHGFIESGT-------------------------FYALPQSPQL 254
Query: 115 YHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEFTSCE 5
+ L+V G ++ ++I + FR+E + PEFT +
Sbjct: 255 FKQMLMVSGFDKYYQIARCFRDEDLRADRQPEFTQLD 291
>gi|3377724 (AF079365) silent surface layer protein [Lactobacillus crispatus]
Length = 452
Score = 34.8 bits (78), Expect = 0.65
Identities = 16/56 (28%), Positives = 30/56 (53%)
Query: 679 TCQSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGKTNLK 512
T ++N+ + ++T+ IG NFY+++ DG+ + I A+N + K LK
Sbjct: 341 TTRANNDKAKRYESVTVAMSTKKIGDKNFYEVIKDGKATSMYINADNIDGTKRTLK 396
>gi|2500990|sp|Q57911|SYF_METJA PROBABLE PHENYLALANYL-TRNA SYNTHETASE (PHENYLALANINE--TRNA LIGASE)
>gi|2129182|pir||G64360 phenylalanine--tRNA ligase (EC
6.1.1.20) alpha chain - Methanococcus jannaschii
>gi|1592293 (U67499) phenylalanyl-tRNA synthetase,
subunit alpha (pheS) [Methanococcus jannaschii]
Length = 480
Score = 34.4 bits (77), Expect = 0.85
Identities = 15/27 (55%), Positives = 18/27 (66%)
Query: 85 NRVFEIGKQFRNEGIDLTHNPEFTSCE 5
++VF I + FRNE ID H PEF CE
Sbjct: 343 HKVFCIDRVFRNEAIDYKHLPEFYQCE 369
>gi|2305222 (AF012089) phenylalanyl tRNA synthetase [Drosophila melanogaster]
Length = 452
Score = 32.8 bits (73), Expect = 2.5
Identities = 15/40 (37%), Positives = 22/40 (54%)
Query: 136 LRVSPELYHXKLIVGGLNRVFEIGKQFRNEGIDLTHNPEF 17
LR + +LI GGL+ +G+ +R + ID TH P F
Sbjct: 137 LRAHTTAHQVELISGGLDNFLVVGEVYRRDEIDSTHYPVF 176
>gi|2128703|pir||F64444 hypothetical protein MJ1159 - Methanococcus jannaschii >gi|1500014
(U67558) replication factor A related protein
[Methanococcus jannaschii]
Length = 645
Score = 32.8 bits (73), Expect = 2.5
Identities = 36/88 (40%), Positives = 48/88 (53%), Gaps = 11/88 (12%)
Query: 703 KEIKSKYSTCQSNSKSE--EEVSMAGRVIATRNIGRVNFYKILDDGEI--IQIVIIANNA 536
++I+S+ + +K E E VS+ GRVIA N V+ DGEI +Q +I+ N
Sbjct: 270 EKIESEEVNIEDLTKYEDGELVSVKGRVIAISNKKSVDL-----DGEIAKVQDIILDNGT 324
Query: 535 ED-------GKTNLKEMVXNIKRGDIVGFTGYPGKTKTD 440
GKT L E NIK GD+V T KT D
Sbjct: 325 GRVRVSFWRGKTALLE---NIKEGDLVRITNCRVKTFYD 360
>gi|541344|pir||S42927 probable transport protein - Staphylococcus epidermidis
>gi|459262|emb|CAA83061| (Z30586) ABC transporter
(putative) [Staphylococcus epidermidis]
Length = 231
Score = 32.5 bits (72), Expect = 3.3
Identities = 15/35 (42%), Positives = 21/35 (59%)
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFV 422
KT LK++ N+KRG IVG G G KT + + +
Sbjct: 16 KTILKDISLNLKRGQIVGLVGANGAGKTSLMKVIL 50
>gi|1086133|pir||S42931 potential ABC transporter - Staphylococcus hominis
>gi|459265|emb|CAA83063| (Z30587) Potential ABC
transporter [Staphylococcus hominis]
Length = 231
Score = 32.5 bits (72), Expect = 3.3
Identities = 15/35 (42%), Positives = 21/35 (59%)
Query: 526 KTNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFV 422
KT LK++ N+KRG IVG G G KT + + +
Sbjct: 16 KTILKDISLNLKRGQIVGLVGANGAGKTSLMKVIL 50
>gi|4127381|emb|CAA09487| (AJ011104) elongation factor G [Apple proliferation phytoplasma]
Length = 688
Score = 32.5 bits (72), Expect = 3.3
Identities = 25/91 (27%), Positives = 44/91 (47%), Gaps = 10/91 (10%)
Query: 673 QSNSKSEEEVSMAGRVIATRNIGRVNFYKILDDGEIIQIVIIANNAEDGK---------- 524
+ S +E ++A +V+ +G++ F+++ G I + N + K
Sbjct: 299 RKTSDNEPFTALAFKVMTDPYVGKLTFFRVYA-GTIKTGSYVTNATKQVKERLGRLLQMH 357
Query: 523 TNLKEMVXNIKRGDIVGFTGYPGKTKTDELSIFVDDIIILS 401
N +E + + GDIV G T D L+ DDII+ S
Sbjct: 358 ANSREEIKEVYAGDIVAAVGLKNTTPGDTLTSINDDIILES 398
Database: Non-redundant GenBank CDS
translations+PDB+SwissProt+SPupdate+PIR
Posted date: Apr 17, 1999 5:33 AM
Number of letters in database: 113,023,754
Number of sequences in database: 369,800
Lambda K H
0.318 0.135 0.00
Gapped
Lambda K H
0.270 0.0470 4.94e-324
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106162135
Number of Sequences: 369800
Number of extensions: 1789450
Number of successful extensions: 4608
Number of sequences better than 10.0: 196
Number of HSP's better than 10.0 without gapping: 90
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 4445
Number of HSP's gapped (non-prelim): 103
length of query: 239
length of database: 113,023,754
effective HSP length: 53
effective length of query: 186
effective length of database: 93424354
effective search space: 17376929844
effective search space used: 17376929844
frameshift window, decay const: 50, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 68 (30.9 bits)